Long-chain acylcarnitines activate cell stress and myokine release in C2C12 myotubes: Calcium-dependent and -independent effects

American Journal of Physiology - Endocrinology and Metabolism

Volumn 308, Issue 11, 2015, Pages E990-E1000

  McCoin, Colin S ^a   Knotts, Trina A ^a,b   Ono Moore, Kikumi D ^b   Oort, Pieter J ^b   Adams, Sean H ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b AGRICULTURAL RESEARCH SERVICE   (United States)

^c UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Cell death; Interleukin 6; Skeletal muscle

Indexed keywords

ACYLCARNITINE; AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; CASPASE 3; INTERLEUKIN 6; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN C JUN; CALCIUM; CARNITINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL DAMAGE; CELL DEATH; CELL DIFFERENTIATION; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CELL STRESS; CELLULAR STRESS SIGNAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DOSE RESPONSE; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; INFLAMMATION; INSULIN SENSITIVITY; MOUSE; MYOBLAST; MYOTUBE; NONHUMAN; OXIDATION REDUCTION POTENTIAL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN UNFOLDING; SKELETAL MUSCLE; ANALOGS AND DERIVATIVES; ANIMAL; CELL LINE; CHEMISTRY; DRUG EFFECTS; METABOLISM; PHYSIOLOGICAL STRESS; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

ANIMALS; CALCIUM; CARNITINE; CELL DEATH; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM STRESS; INTERLEUKIN-6; MAP KINASE SIGNALING SYSTEM; MICE; MUSCLE FIBERS, SKELETAL; STRESS, PHYSIOLOGICAL; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84930844045     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00602.2014     Document Type: Article

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