Matrix stiffness-modulated proliferation and secretory function of the airway smooth muscle cells

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 308, Issue 11, 2015, Pages L1125-L1135

  Shkumatov, Artem ^a   Thompson, Michael ^b   Choi, Kyoung M ^c   Sicard, Delphine ^c   Baek, Kwanghyun ^d   Kim, Dong Hyun ^e   Tschumperlin, Daniel J ^c   Prakash, Y S ^b   Kong, Hyunjoon ^a,f  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b DEPARTMENT OF UROLOGY   (United States)

^c MAYO GRADUATE SCHOOL   (United States)

^d United States of America   (United States)

^e Korea Institute of Industrial Technology   (South Korea)

^f Department of Chemical Engineering Soongshil University   (South Korea)

Author keywords

Airways smooth muscle cells; Asthma; Hydrogel; Integrin; Matrix stiffness

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BETA1 INTEGRIN; CALCIUM; COLLAGEN; HISTAMINE; INTEGRIN LINKED KINASE; POLYACRYLAMIDE; SCLEROPROTEIN; VASCULOTROPIN; CULTURE MEDIUM; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

ACTIN FILAMENT; ACTIN POLYMERIZATION; ADHERENT CELL; AIRWAY SMOOTH MUSCLE CELL; ARTICLE; ATOMIC FORCE MICROSCOPY; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL ADHESION; CELL FUNCTION; CELL HYPERPLASIA; CELL MATRIX STIFFNESS; CELL PROLIFERATION; CELLULAR PARAMETERS; CELLULAR SECRETION; CONTROLLED STUDY; EMPHYSEMA; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; HYDROGEL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RIGIDITY; YOUNG MODULUS; AIRWAY RESISTANCE; ANIMAL; C57BL MOUSE; CELL CULTURE; CULTURE MEDIUM; LUNG; METABOLISM; PHYSIOLOGY; SECRETION (PROCESS); SMOOTH MUSCLE FIBER; ULTRASTRUCTURE;

ACTIN CYTOSKELETON; AIRWAY RESISTANCE; ANIMALS; ANTIGENS, CD29; CELL ADHESION; CELL PROLIFERATION; CELLS, CULTURED; CULTURE MEDIA; ELASTIC MODULUS; HUMANS; LUNG; MICE, INBRED C57BL; MYOCYTES, SMOOTH MUSCLE; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84930836118     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00154.2014     Document Type: Article

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