Mesenchymal Stem Cells Reduce Colitis in Mice via Release of TSG6, Independently of Their Localization to the Intestine

Gastroenterology

Volumn 149, Issue 1, 2015, Pages 163-176.e20

  Sala, Emanuela ^a   Genua, Marco ^a   Petti, Luciana ^a   Anselmo, Achille ^a   Arena, Vincenzo ^b   Cibella, Javier ^a   Zanotti, Lucia ^a   D'Alessio, Silvia ^a   Scaldaferri, Franco ^b   Luca, Giovanni ^c   Arato, Iva ^c   Calafiore, Riccardo ^c   Sgambato, Alessandro ^b   Rutella, Sergio ^d   Locati, Massimo ^e   Danese, Silvio ^a   Vetrano, Stefania ^a,f  

^a HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^b CATHOLIC UNIVERSITY   (Italy)

^c UNIVERSITY OF PERUGIA   (Italy)

^d SIDRA MEDICAL AND RESEARCH CENTER   (Qatar)

^e UNIVERSITY OF MILAN   (Italy)

^f HUMANITAS UNIVERSITY   (Italy)

Author keywords

Experimental Models of Colitis; IBD; Immune Regulation; Mesenchymal Stem Cell Based Therapy

Indexed keywords

AGENTS USED IN INFLAMMATORY BOWEL DISEASE; ARGINASE; ARGINASE TYPE II; CD45 ANTIGEN; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR3; CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CCR6; CHEMOKINE RECEPTOR CCR7; CHEMOKINE RECEPTOR CCR8; CHEMOKINE RECEPTOR CCR9; DEXTRAN SULFATE; GAMMA INTERFERON; GELATINASE B; GREEN FLUORESCENT PROTEIN; HEME OXYGENASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 6; MACROPHAGE DERIVED CHEMOKINE; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; RECOMBINANT TUMOR NECROSIS FACTOR INDUCED PROTEIN 6; SODIUM CHLORIDE; STROMELYSIN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; TRINITROBENZENESULFONIC ACID; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; CELL ADHESION MOLECULE; CYTOKINE; TNFAIP6 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BLOOD SAMPLING; BODY WEIGHT; BONE MARROW DERIVED MESENCHYMAL STEM CELL; CELL AGGREGATION; CELLULAR DISTRIBUTION; COLON MUCOSA; CONTROLLED STUDY; CYTOKINE RELEASE; DEXTRAN SODIUM SULFATE-INDUCED COLITIS; DISEASE SEVERITY; ENTERITIS; EXPERIMENTAL COLITIS; FEMALE; HISTOPATHOLOGY; IMMUNOREGULATION; INTESTINE; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MOUSE; NEUTROPHIL; NONHUMAN; PARACRINE SIGNALING; PERITONEAL CAVITY; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; SINGLE DRUG DOSE; STEM CELL EXPANSION; T LYMPHOCYTE; ANIMAL; C57BL MOUSE; COLITIS; CYTOLOGY; DISEASE MODEL; IMMUNOLOGY; MESENCHYMAL STROMA CELL; METABOLISM; PROCEDURES; TREATMENT OUTCOME;

ANIMALS; CELL ADHESION MOLECULES; COLITIS; CYTOKINES; DEXTRAN SULFATE; DISEASE MODELS, ANIMAL; INTESTINES; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED C57BL; TREATMENT OUTCOME;

EID: 84930822030     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2015.03.013     Document Type: Article

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