MT-7716, a potent NOP receptor agonist, preferentially reduces ethanol seeking and reinforcement in post-dependent rats

Addiction Biology

Volumn 20, Issue 4, 2015, Pages 643-651

  De Guglielmo, Giordano ^a,b   Martin Fardon, Rémi ^a   Teshima, Koji ^c   Ciccocioppo, Roberto ^b   Weiss, Friedbert ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CAMERINO   (Italy)

^c MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

Addiction; alcohol; MT 7716; nociceptin orphanin FQ; reinstatement; self administration; stress

Indexed keywords

2 [7 [1 (ACENAPHTHEN 1 YL)PIPERIDIN 4 YL] 2 OXO 2,3 DIHYDRO 1H BENZIMIDAZOL 1 YL] N METHYLACETAMIDE HYDROCHLORIDE; ALCOHOL; NOCICEPTIN RECEPTOR AGONIST; UNCLASSIFIED DRUG; 2-(3-(1-(ACENAPHTHEN-1-YL)PIPERIDIN-4-YL)-2-OXO-2,3-DIHYDRO-1H-BENZIMIDAZOL-1-YL)-N-METHYLACETAMIDE; ACENAPHTHENE DERIVATIVE; BENZIMIDAZOLE DERIVATIVE; NARCOTIC ANTAGONIST; NOCICEPTIN; NOCICEPTIN RECEPTOR; OPIATE PEPTIDE; OPIATE RECEPTOR;

ALCOHOL BLOOD LEVEL; ALCOHOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REINFORCEMENT; SELF ADMINISTRATION TEST; WISTAR RAT; ANALYSIS OF VARIANCE; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; DRUG EFFECTS; DRUG SEEKING BEHAVIOR; DRUG SELF ADMINISTRATION; INSTRUMENTAL CONDITIONING; MENTAL STRESS; METABOLISM; NOCICEPTION; PSYCHOLOGY;

ACENAPHTHENES; ALCOHOLISM; ANALYSIS OF VARIANCE; ANIMALS; BENZIMIDAZOLES; CONDITIONING, OPERANT; DRUG-SEEKING BEHAVIOR; ETHANOL; MALE; NARCOTIC ANTAGONISTS; NOCICEPTION; OPIOID PEPTIDES; RATS, WISTAR; RECEPTORS, OPIOID; REINFORCEMENT (PSYCHOLOGY); SELF ADMINISTRATION; STRESS, PSYCHOLOGICAL;

EID: 84930818713     PISSN: 13556215     EISSN: 13691600     Source Type: Journal    
DOI: 10.1111/adb.12157     Document Type: Article

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