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Volumn 109, Issue 1, 2015, Pages 206-212

Polymorphisms of rs174616 in the FADS1-FADS2 gene cluster is associated with a reduced risk of type 2 diabetes mellitus in northern Han Chinese people

Author keywords

Arachidonic acid; Desaturase; FADS1 FADS2 gene cluster; PUFA; Type 2 diabetes mellitus

Indexed keywords

ACYL COENZYME A DESATURASE; ACYL COENZYME A DESATURASE 1; ARACHIDONIC ACID; ICOSAPENTAENOIC ACID; LINOLEIC ACID; LINOLENIC ACID; LINOLEOYL COENZYME A DESATURASE; PROTEIN FADS2; THYMINE; UNCLASSIFIED DRUG; DELTA-5 FATTY ACID DESATURASE; FADS2 PROTEIN, HUMAN;

EID: 84930818508     PISSN: 01688227     EISSN: 18728227     Source Type: Journal    
DOI: 10.1016/j.diabres.2015.03.009     Document Type: Article
Times cited : (19)

References (30)
  • 1
    • 84866268783 scopus 로고    scopus 로고
    • Management of hyperglycemia in type 2 diabetes: a patient-centered approach: position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
    • Inzucchi S.E., Bergenstal R.M., Buse J.B., Diamant M., Ferrannini E., Nauck M., et al. Management of hyperglycemia in type 2 diabetes: a patient-centered approach: position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care 2012, 35:1364-1379.
    • (2012) Diabetes Care , vol.35 , pp. 1364-1379
    • Inzucchi, S.E.1    Bergenstal, R.M.2    Buse, J.B.3    Diamant, M.4    Ferrannini, E.5    Nauck, M.6
  • 2
    • 84876793274 scopus 로고    scopus 로고
    • Metabolic inflexibility of white and brown adipose tissues in abnormal fatty acid partitioning of type 2 diabetes
    • Grenier-Larouche T., Labbé S.M., Noll C., et al. Metabolic inflexibility of white and brown adipose tissues in abnormal fatty acid partitioning of type 2 diabetes. Int J Obesity Suppl 2012, 2:S37-S42. 10.1038/ijosup.2012.21.
    • (2012) Int J Obesity Suppl , vol.2 , pp. S37-S42
    • Grenier-Larouche, T.1    Labbé, S.M.2    Noll, C.3
  • 3
    • 84859219589 scopus 로고    scopus 로고
    • Lower serum paraoxonase-1 activity is related to linoleic and docosahexanoic fatty acids in type 2 diabetic patients
    • Rasic-Milutinovic Z., Popovic T., Perunicic-Pekovic G., Arsic A., Borozan S., Glibetic M. Lower serum paraoxonase-1 activity is related to linoleic and docosahexanoic fatty acids in type 2 diabetic patients. Arch Med Res 2012, 43:75-82.
    • (2012) Arch Med Res , vol.43 , pp. 75-82
    • Rasic-Milutinovic, Z.1    Popovic, T.2    Perunicic-Pekovic, G.3    Arsic, A.4    Borozan, S.5    Glibetic, M.6
  • 4
    • 84903378556 scopus 로고    scopus 로고
    • Genetic variants in desaturase gene, erythrocyte fatty acids, and risk for type 2 diabetes in Chinese Hans
    • Huang T., Sun J., Chen Y., Xie H., Xu D., Huang J., et al. Genetic variants in desaturase gene, erythrocyte fatty acids, and risk for type 2 diabetes in Chinese Hans. Nutrition 2014, 30:897-902.
    • (2014) Nutrition , vol.30 , pp. 897-902
    • Huang, T.1    Sun, J.2    Chen, Y.3    Xie, H.4    Xu, D.5    Huang, J.6
  • 5
    • 78651287448 scopus 로고    scopus 로고
    • Erythrocyte membrane phospholipid fatty acids, desaturase activity, and dietary fatty acids in relation to risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study
    • Kroger J., Zietemann V., Enzenbach C., Weikert C., Jansen E.H., Doring F., et al. Erythrocyte membrane phospholipid fatty acids, desaturase activity, and dietary fatty acids in relation to risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study. Am J Clin Nutr 2011, 93:127-142.
    • (2011) Am J Clin Nutr , vol.93 , pp. 127-142
    • Kroger, J.1    Zietemann, V.2    Enzenbach, C.3    Weikert, C.4    Jansen, E.H.5    Doring, F.6
  • 6
    • 84908015542 scopus 로고    scopus 로고
    • Plasma polyunsaturated fatty acid profile and delta-5 desaturase activity are altered in patients with type 2 diabetes
    • Imamura S., Morioka T., Yamazaki Y., Numaguchi R., Urata H., Motoyama K., et al. Plasma polyunsaturated fatty acid profile and delta-5 desaturase activity are altered in patients with type 2 diabetes. Metabolism 2014, 63:1432-1438.
    • (2014) Metabolism , vol.63 , pp. 1432-1438
    • Imamura, S.1    Morioka, T.2    Yamazaki, Y.3    Numaguchi, R.4    Urata, H.5    Motoyama, K.6
  • 7
    • 84872041909 scopus 로고    scopus 로고
    • Models of plasma membrane organization can be applied to mitochondrial membranes to target human health and disease with polyunsaturated fatty acids
    • Raza Shaikh S., Brown D.A. Models of plasma membrane organization can be applied to mitochondrial membranes to target human health and disease with polyunsaturated fatty acids. Prostaglandins Leukot Essent Fatty Acids 2013, 88:21-25.
    • (2013) Prostaglandins Leukot Essent Fatty Acids , vol.88 , pp. 21-25
    • Raza Shaikh, S.1    Brown, D.A.2
  • 8
    • 84922553466 scopus 로고    scopus 로고
    • Marine omega-3 fatty acids and inflammatory processes: effects, mechanisms and clinical relevance
    • Calder P.C. Marine omega-3 fatty acids and inflammatory processes: effects, mechanisms and clinical relevance. Biochim Biophys Acta 2015, 185(4):469-484.
    • (2015) Biochim Biophys Acta , vol.185 , Issue.4 , pp. 469-484
    • Calder, P.C.1
  • 9
    • 80054121197 scopus 로고    scopus 로고
    • Fatty acids as biocompounds: their role in human metabolism, health and disease: a review. Part 2: fatty acid physiological roles and applications in human health and disease
    • Kremmyda L.S., Tvrzicka E., Stankova B., Zak A. Fatty acids as biocompounds: their role in human metabolism, health and disease: a review. Part 2: fatty acid physiological roles and applications in human health and disease. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2011, 155(3):195-218.
    • (2011) Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub , vol.155 , Issue.3 , pp. 195-218
    • Kremmyda, L.S.1    Tvrzicka, E.2    Stankova, B.3    Zak, A.4
  • 10
    • 84872106164 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids omega-3 as modulators of intracellular signaling pathways
    • Duda M.K. Polyunsaturated fatty acids omega-3 as modulators of intracellular signaling pathways. Postepy Biochem 2012, 58:149-154.
    • (2012) Postepy Biochem , vol.58 , pp. 149-154
    • Duda, M.K.1
  • 11
    • 3142753961 scopus 로고    scopus 로고
    • Structure, function, and dietary regulation of delta6, delta5, and delta9 desaturases
    • Nakamura M.T., Nara T.Y. Structure, function, and dietary regulation of delta6, delta5, and delta9 desaturases. Annu Rev Nutr 2004, 24:345-376.
    • (2004) Annu Rev Nutr , vol.24 , pp. 345-376
    • Nakamura, M.T.1    Nara, T.Y.2
  • 12
    • 55949102407 scopus 로고    scopus 로고
    • Genetic variants of the FADS1 FADS2 gene cluster are associated with altered (n-6) and (n-3) essential fatty acids in plasma and erythrocyte phospholipids in women during pregnancy and in breast milk during lactation
    • Xie L., Innis S.M. Genetic variants of the FADS1 FADS2 gene cluster are associated with altered (n-6) and (n-3) essential fatty acids in plasma and erythrocyte phospholipids in women during pregnancy and in breast milk during lactation. J Nutr 2008, 138:2222-2228.
    • (2008) J Nutr , vol.138 , pp. 2222-2228
    • Xie, L.1    Innis, S.M.2
  • 13
    • 84876791563 scopus 로고    scopus 로고
    • Interaction between a common variant in FADS1 and erythrocyte polyunsaturated fatty acids on lipid profile in Chinese Hans
    • Zhu J., Sun Q., Zong G., Si Y., Liu C., Qi Q., et al. Interaction between a common variant in FADS1 and erythrocyte polyunsaturated fatty acids on lipid profile in Chinese Hans. J Lipid Res 2013, 54:1477-1483.
    • (2013) J Lipid Res , vol.54 , pp. 1477-1483
    • Zhu, J.1    Sun, Q.2    Zong, G.3    Si, Y.4    Liu, C.5    Qi, Q.6
  • 14
    • 77955425717 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in the FADS gene cluster are associated with delta-5 and delta-6 desaturase activities estimated by serum fatty acid ratios
    • Bokor S., Dumont J., Spinneker A., Gonzalez-Gross M., Nova E., Widhalm K., et al. Single nucleotide polymorphisms in the FADS gene cluster are associated with delta-5 and delta-6 desaturase activities estimated by serum fatty acid ratios. J Lipid Res 2010, 51:2325-2333.
    • (2010) J Lipid Res , vol.51 , pp. 2325-2333
    • Bokor, S.1    Dumont, J.2    Spinneker, A.3    Gonzalez-Gross, M.4    Nova, E.5    Widhalm, K.6
  • 15
    • 78651301789 scopus 로고    scopus 로고
    • Genetic variants of the fatty acid desaturase gene cluster predict amounts of red blood cell docosahexaenoic and other polyunsaturated fatty acids in pregnant women: findings from the Avon Longitudinal Study of Parents and Children
    • Koletzko B., Lattka E., Zeilinger S., Illig T., Steer C. Genetic variants of the fatty acid desaturase gene cluster predict amounts of red blood cell docosahexaenoic and other polyunsaturated fatty acids in pregnant women: findings from the Avon Longitudinal Study of Parents and Children. Am J Clin Nutr 2011, 93:211-219.
    • (2011) Am J Clin Nutr , vol.93 , pp. 211-219
    • Koletzko, B.1    Lattka, E.2    Zeilinger, S.3    Illig, T.4    Steer, C.5
  • 16
    • 59249096217 scopus 로고    scopus 로고
    • Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study
    • Tanaka T., Shen J., Abecasis G.R., Kisialiou A., Ordovas J.M., Guralnik J.M., et al. Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study. PLoS Genet 2009, 5:e1000338.
    • (2009) PLoS Genet , vol.5 , pp. e1000338
    • Tanaka, T.1    Shen, J.2    Abecasis, G.R.3    Kisialiou, A.4    Ordovas, J.M.5    Guralnik, J.M.6
  • 17
    • 79956263594 scopus 로고    scopus 로고
    • Polymorphisms in FADS1 and FADS2 alter desaturase activity in young Caucasian and Asian adults
    • Merino D.M., Johnston H., Clarke S., Roke K., Nielsen D., et al. Polymorphisms in FADS1 and FADS2 alter desaturase activity in young Caucasian and Asian adults. Mol Genet Metab 2011, 103:171-178.
    • (2011) Mol Genet Metab , vol.103 , pp. 171-178
    • Merino, D.M.1    Johnston, H.2    Clarke, S.3    Roke, K.4    Nielsen, D.5
  • 18
    • 84873192744 scopus 로고    scopus 로고
    • FADS gene polymorphisms confer the risk of coronary artery disease in a Chinese Han population through the altered desaturase activities: based on high-resolution melting analysis
    • Li S.W., Lin K., Ma P., Zhang Z.L., Zhou Y.D., Lu S.Y., et al. FADS gene polymorphisms confer the risk of coronary artery disease in a Chinese Han population through the altered desaturase activities: based on high-resolution melting analysis. PLOS ONE 2013, 8:e55869.
    • (2013) PLOS ONE , vol.8 , pp. e55869
    • Li, S.W.1    Lin, K.2    Ma, P.3    Zhang, Z.L.4    Zhou, Y.D.5    Lu, S.Y.6
  • 19
    • 78650842083 scopus 로고    scopus 로고
    • FADS gene polymorphisms in Koreans: association with omega6 polyunsaturated fatty acids in serum phospholipids, lipid peroxides, and coronary artery disease
    • Kwak J.H., Paik J.K., Kim O.Y., Jang Y., Lee S.H., Ordovas J.M., Lee J.H. FADS gene polymorphisms in Koreans: association with omega6 polyunsaturated fatty acids in serum phospholipids, lipid peroxides, and coronary artery disease. Atherosclerosis 2011, 214:94-100.
    • (2011) Atherosclerosis , vol.214 , pp. 94-100
    • Kwak, J.H.1    Paik, J.K.2    Kim, O.Y.3    Jang, Y.4    Lee, S.H.5    Ordovas, J.M.6    Lee, J.H.7
  • 20
    • 53849097341 scopus 로고    scopus 로고
    • FADS genotypes and desaturase activity estimated by the ratio of arachidonic acid to linoleic acid are associated with inflammation and coronary artery disease
    • Martinelli N., Girelli D., Malerba G., Guarini P., Illig T., Trabetti E., et al. FADS genotypes and desaturase activity estimated by the ratio of arachidonic acid to linoleic acid are associated with inflammation and coronary artery disease. Am J Clin Nutr 2008, 88:941-949.
    • (2008) Am J Clin Nutr , vol.88 , pp. 941-949
    • Martinelli, N.1    Girelli, D.2    Malerba, G.3    Guarini, P.4    Illig, T.5    Trabetti, E.6
  • 21
    • 78149273926 scopus 로고    scopus 로고
    • Fatty acids measured in plasma and erythrocyte-membrane phospholipids and derived by food-frequency questionnaire and the risk of new-onset type 2 diabetes: a pilot study in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk cohort
    • Patel P.S., Sharp S.J., Jansen E., Luben R.N., Khaw K.T., Wareham N.J., Forouhi N.G. Fatty acids measured in plasma and erythrocyte-membrane phospholipids and derived by food-frequency questionnaire and the risk of new-onset type 2 diabetes: a pilot study in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk cohort. Am J Clin Nutr 2010, 92:1214-1222.
    • (2010) Am J Clin Nutr , vol.92 , pp. 1214-1222
    • Patel, P.S.1    Sharp, S.J.2    Jansen, E.3    Luben, R.N.4    Khaw, K.T.5    Wareham, N.J.6    Forouhi, N.G.7
  • 22
    • 84867234920 scopus 로고    scopus 로고
    • Reduction of n-3 PUFAs, specifically DHA and EPA, and enhancement of peroxisomal beta-oxidation in type 2 diabetic rat heart
    • Hou L., Lian K., Yao M., Shi Y., Lu X., Fang L., et al. Reduction of n-3 PUFAs, specifically DHA and EPA, and enhancement of peroxisomal beta-oxidation in type 2 diabetic rat heart. Cardiovasc Diabetol 2012, 11:126.
    • (2012) Cardiovasc Diabetol , vol.11 , pp. 126
    • Hou, L.1    Lian, K.2    Yao, M.3    Shi, Y.4    Lu, X.5    Fang, L.6
  • 23
    • 84891462249 scopus 로고    scopus 로고
    • Association of erythrocyte membrane fatty acids with changes in glycemia and risk of type 2 diabetes
    • Mahendran Y., Agren J., Uusitupa M., Cederberg H., Vangipurapu J., Stancakova A., et al. Association of erythrocyte membrane fatty acids with changes in glycemia and risk of type 2 diabetes. Am J Clin Nutr 2014, 99:79-85.
    • (2014) Am J Clin Nutr , vol.99 , pp. 79-85
    • Mahendran, Y.1    Agren, J.2    Uusitupa, M.3    Cederberg, H.4    Vangipurapu, J.5    Stancakova, A.6
  • 24
    • 79151478555 scopus 로고    scopus 로고
    • Type 2 diabetes as an inflammatory disease
    • Donath M.Y., Shoelson S.E. Type 2 diabetes as an inflammatory disease. Nat Rev Immunol 2011, 11:98-107.
    • (2011) Nat Rev Immunol , vol.11 , pp. 98-107
    • Donath, M.Y.1    Shoelson, S.E.2
  • 25
    • 84856752552 scopus 로고    scopus 로고
    • Differences in arachidonic acid levels and fatty acid desaturase (FADS) gene variants in African Americans and European Americans with diabetes or the metabolic syndrome
    • Sergeant S., Hugenschmidt C.E., Rudock M.E., Ziegler J.T., Ivester P., Ainsworth H.C., et al. Differences in arachidonic acid levels and fatty acid desaturase (FADS) gene variants in African Americans and European Americans with diabetes or the metabolic syndrome. Br J Nutr 2012, 107:547-555.
    • (2012) Br J Nutr , vol.107 , pp. 547-555
    • Sergeant, S.1    Hugenschmidt, C.E.2    Rudock, M.E.3    Ziegler, J.T.4    Ivester, P.5    Ainsworth, H.C.6
  • 26
    • 84855833330 scopus 로고    scopus 로고
    • Recent insights into the relation of Delta5 desaturase and Delta6 desaturase activity to the development of type 2 diabetes
    • Kroger J., Schulze M.B. Recent insights into the relation of Delta5 desaturase and Delta6 desaturase activity to the development of type 2 diabetes. Curr Opin Lipidol 2012, 23:4-10.
    • (2012) Curr Opin Lipidol , vol.23 , pp. 4-10
    • Kroger, J.1    Schulze, M.B.2
  • 28
    • 77956165390 scopus 로고    scopus 로고
    • GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects
    • Oh D.Y., Talukdar S., Bae E.J., Imamura T., Morinaga H., Fan W., et al. GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects. Cell 2010, 142:687-698.
    • (2010) Cell , vol.142 , pp. 687-698
    • Oh, D.Y.1    Talukdar, S.2    Bae, E.J.3    Imamura, T.4    Morinaga, H.5    Fan, W.6
  • 29
    • 82955188750 scopus 로고    scopus 로고
    • N-3 PUFA supplementation triggers PPAR-alpha activation and PPAR-alpha/NF-kappaB interaction: anti-inflammatory implications in liver ischemia-reperfusion injury
    • Zuniga J., Cancino M., Medina F., Varela P., Vargas R., Tapia G., et al. n-3 PUFA supplementation triggers PPAR-alpha activation and PPAR-alpha/NF-kappaB interaction: anti-inflammatory implications in liver ischemia-reperfusion injury. PLoS ONE 2011, 6:e28502.
    • (2011) PLoS ONE , vol.6 , pp. e28502
    • Zuniga, J.1    Cancino, M.2    Medina, F.3    Varela, P.4    Vargas, R.5    Tapia, G.6


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