Loss of ATP-dependent lysine uptake in the vacuolar membrane vesicles of Saccharomyces cerevisiae ypq1Δ mutant

Bioscience, Biotechnology and Biochemistry

Volumn 78, Issue 7, 2014, Pages 1199-1202

  Sekito, Takayuki ^a   Nakamura, Kyosuke ^a   Manabe, Kunio ^a   Tone, Junichi ^a   Sato, Yumika ^a   Murao, Nami ^a   Kawano Kawada, Miyuki ^a   Kakinuma, Yoshimi Kakinuma ^a  

^a EHIME UNIVERSITY   (Japan)

Author keywords

Lysine; PQ loop; Transport; Vacuole

Indexed keywords

BIOLOGICAL MEMBRANES; PROTEINS; YEAST;

LYSINE; PQ-LOOP; PROTEIN FAMILY; TRANSPORT; VACUOLAR MEMBRANES; VACUOLE;

AMINO ACIDS;

SACCHAROMYCES CEREVISIAE;

ADENOSINE TRIPHOSPHATE; LYSINE; MEMBRANE PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; YPQ1 PROTEIN, S CEREVISIAE;

CELL VACUOLE; CYTOLOGY; GENETICS; INTRACELLULAR MEMBRANE; METABOLISM; MUTATION; SACCHAROMYCES CEREVISIAE; TRANSPORT AT THE CELLULAR LEVEL;

ADENOSINE TRIPHOSPHATE; BIOLOGICAL TRANSPORT; INTRACELLULAR MEMBRANES; LYSINE; MEMBRANE PROTEINS; MUTATION; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; VACUOLES;

EID: 84930733719     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1080/09168451.2014.918489     Document Type: Article

References (20)

1. Yee DC, Shlykov MA, Vastermark A, Reddy VS, Arora S, Sun EI, Saier MH Jr. Characterization of amino acid pools in the vacuolar compartment of Saccharomyces cerevisiae. FEBS J. 2013;280:5780-5800.
2. Cherqui S, Kalatzis V, Trugnan G, Antignac C. The targeting of cystinosin to the lysosomal membrane requires a tyrosine-based signal and a novel sorting motif. J. Biol. Chem. 2001;276:13314-13321.
3. Ruivo R, Bellenchi GC, Chen X, Zifarelli G, Sagne C, Debacker C, Pusch M, Supplisson S, Gasnier B. Mechanism of proton/substrate coupling in the heptahelical lysosomal transporter cystinosin. Proc. Nat. Acad. Sci. USA. 2012;109:210-217.
4. + encoding a seven-transmembrane loop protein that may couple with the heterotrimeric Gα2 protein, Gpa2. J. Biol. Chem. 2001;276:40190-40201.
5. Jézégou A, Llinares E, Anne C, Kieffer-Jaquinod S, O'Regan S, Aupetit J, Chabli A, Sagne C, Debacker C, Chadefaux-Vekemans B, Journet A, Andre B, Gasnier B. Heptahelical protein PQLC2 is a lysosomal cationic amino acid exporter underlying the action of cysteamine in cystinosis therapy. Proc. Nat. Acad. Sci. 2012;109:3434-3443.
6. Sekito T, Chardwiriyapreecha S, Sugimoto N, Ishimoto M, Kawano-Kawada M, Kakinuma Y. Vacuolar transporter Avt4 is involved in excretion of basic amino acids from the vacuoles of Saccharomyces cerevisiae. Biosci. Biotechnol. Biochem. Forthcoming.
7. Mumberg D, Muller R, Funk M. Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds. Gene. 1995;156:119-122.
8. Ohsumi Y, Anraku Y. Active transport of basic amino acids driven by a proton motive force in vacuolar membrane vesicles of Saccharomyces cerevisiae. J. Biol. Chem. 1981;256:2079-2082.
9. Ohsumi Y, Anraku Y. Calcium transport driven by a proton motive force in vacuolar membrane vesicles of Saccharomyces cerevisiae. J. Biol. Chem. 1983;258:5614-5617.
10. Nishimura K, Igarashi K, Kakinuma Y. Proton gradient-driven nickel uptake by vacuolar membrane vesicles of Saccharomyces cerevisiae. J. Bacteriol. 1998;180:1962-1964.
11. Russnak R, Konczal D, McIntire SL. A family of yeast proteins mediating bidirectional vacuolar amino acid transport. J. Biol. Chem. 2001;276:23849-23857.
12. Shimazu M, Sekito T, Akiyama K, Ohsumi Y, Kakinuma Y. A family of basic amino acid transporters of the vacuolar membrane from Saccharomyces cerevisiae. J. Biol. Chem. 2005;280:4851-4857.
13. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 1951;193:265-275.
14. +-translocating adenosine triphosphatase in vacuolar membranes of Saccharomyces cerevisiae. J. Biol. Chem. 1981;256:10859-10863.
15. + genes for vacuolar amino acid transporters in Schizosaccharomyces pombe. FEBS Lett. 2008;582:2225-2230.
16. Chahomchuen T, Hondo K, Ohsaki M, Sekito T, Kakinuma Y. Evidence for Avt6 as a vacuolar exporter of acidic amino acids in Saccharomyces cerevisiae cells. J. Gen. Appl. Microbiol. 2009;55:409-417.
17. Stanbrough M, Magasanik B. Transcriptional and posttranslational regulation of the general amino acid permease of Saccharomyces cerevisiae. J. Bacteriol. 1995;177:94-102.
18. Merhi A, Andre B. Internal amino acids promote Gap1 permease ubiquitylation via TORC1/Npr1/14-3-3-dependent control of the Bul arrestin-like adaptors. Mol. Cell. Biol. 2012;32:4510-4522.
19. Cox KH, Rai R, Distler M, Daugherty JR, Coffman JA, Cooper TG. Saccharomyces cerevisiae GATA sequences function as TATA elements during nitrogen catabolite repression and when Gln3p is excluded from the nucleus by overproduction of Ure2p. J. Biol. Chem. 2000;275:17611-17618.
20. Lin CH, MacGurn JA, Chu T, Stefan CJ, Emr SD. Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface. Cell. 2008;135:714-725.