The N-glycan on Asn54 affects the atypical N-glycan composition of plant-produced interleukin-22, but does not influence its activity

Plant Biotechnology Journal

Volumn 14, Issue 2, 2016, Pages 670-681

  Wilbers, Ruud H P ^a   Westerhof, Lotte B ^a   Reuter, Lauri J ^b   Castilho, Alexandra ^c   van Raaij, Debbie R ^a   Nguyen, Dieu Linh ^d   Lozano Torres, Jose L ^a   Smant, Geert ^a   Hokke, Cornelis H ^d   Bakker, Jaap ^a   Schots, Arjen ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b VTT TECHNICAL RESEARCH CENTRE OF FINLAND   (Finland)

^c UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

^d LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Core 1,6 fucose; Glyco engineering; Interleukin 22; Lewis A; N glycosylation; Nicotiana

Indexed keywords

ASPARAGINE; INTERLEUKIN DERIVATIVE; INTERLEUKIN-22; POLYSACCHARIDE;

ANIMAL; BIOSYNTHESIS; DROSOPHILA MELANOGASTER; GENETICS; GLYCOSYLATION; HEK293 CELL LINE; HUMAN; ISOLATION AND PURIFICATION; METABOLIC ENGINEERING; METABOLISM; PLANT LEAF; TOBACCO; TRANSGENIC PLANT;

ANIMALS; ASPARAGINE; DROSOPHILA MELANOGASTER; GLYCOSYLATION; HEK293 CELLS; HUMANS; INTERLEUKINS; METABOLIC ENGINEERING; PLANT LEAVES; PLANTS, GENETICALLY MODIFIED; POLYSACCHARIDES; TOBACCO;

EID: 84930713458     PISSN: 14677644     EISSN: 14677652     Source Type: Journal    
DOI: 10.1111/pbi.12414     Document Type: Article

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