Nitrofen increases total retinol levels in placenta during lung morphogenesis in the nitrofen model of congenital diaphragmatic hernia

Pediatric Surgery International

Volumn 30, Issue 10, 2014, Pages 1017-1022

  Kutasy, Balazs ^a   Pes, Lara ^b   Friedmacher, Florian ^a   Paradisi, Francesca ^b   Puri, Prem ^a,c  

^a OUR LADY S CHILDREN S HOSPITAL   (Ireland)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

^c National Children s Hospital   (Ireland)

Author keywords

Congenital diaphragmatic hernia; Nitrofen; Placenta; Retinol

Indexed keywords

DIPHENYL ETHER DERIVATIVE; NITROFEN; OLIVE OIL; RETINOL; RETINOL BINDING PROTEIN; VEGETABLE OIL;

ANIMAL; BIOSYNTHESIS; CONGENITAL DIAPHRAGM HERNIA; DISEASE MODEL; EMBRYOLOGY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LUNG; METABOLISM; MORPHOGENESIS; PLACENTA; PREGNANCY; PROCEDURES; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DISEASE MODELS, ANIMAL; FEMALE; HERNIAS, DIAPHRAGMATIC, CONGENITAL; LUNG; MORPHOGENESIS; PHENYL ETHERS; PLACENTA; PLANT OILS; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; RETINOL-BINDING PROTEINS; VITAMIN A;

EID: 84930693626     PISSN: 01790358     EISSN: 14379813     Source Type: Journal    
DOI: 10.1007/s00383-014-3525-7     Document Type: Article

References (42)

1. Colvin J, Bower C, Dickinson JE, Sokol J (2005) Outcomes of congenital diaphragmatic hernia: a population-based study in Western Australia. Pediatrics 116(3):e356–e363
2. Stege G, Fenton A, Jaffray B (2003) Nihilism in the 1990s: the true mortality of congenital diaphragmatic hernia. Pediatrics 112(3 Pt 1):532–535
3. Gosche JR, Islam S, Boulanger SC (2005) Congenital diaphragmatic hernia: searching for answers. Am J Surg 190(2):324–332
4. Robinson PD, Fitzgerald DA (2007) Congenital diaphragmatic hernia. Paediatr Respir Rev 8(4):323–334 (quiz 334–325)
5. Montedonico S, Nakazawa N, Puri P (2008) Congenital diaphragmatic hernia and retinoids: searching for an etiology. Pediatr Surg Int 24(7):755–761
6. Noble BR, Babiuk RP, Clugston RD, Underhill TM, Sun H, Kawaguchi R, Walfish PG, Blomhoff R, Gundersen TE, Greer JJ (2007) Mechanisms of action of the congenital diaphragmatic hernia-inducing teratogen nitrofen. Am J Physiol Lung Cell Mol Physiol 293(4):L1079–L1087
7. Clagett-Dame M, DeLuca HF (2002) The role of vitamin A in mammalian reproduction and embryonic development. Annu Rev Nutr 22:347–381
8. Wassef L, Quadro L (2011) Uptake of dietary retinoids at the maternal-fetal barrier: in vivo evidence for the role of lipoprotein lipase and alternative pathways. J Biol Chem 286(37):32198–32207
9. Spiegler E, Kim YK, Wassef L, Shete V, Quadro L (2012) Maternal-fetal transfer and metabolism of vitamin A and its precursor beta-carotene in the developing tissues. Biochim Biophys Acta 1821(1):88–98
10. Sapin V, Chaib S, Blanchon L, Alexandre-Gouabau MC, Lemery D, Charbonne F, Gallot D, Jacquetin B, Dastugue B, Azais-Braesco V (2000) Esterification of vitamin A by the human placenta involves villous mesenchymal fibroblasts. Pediatr Res 48(4):565–572
11. Monaco HL, Rizzi M, Coda A (1995) Structure of a complex of two plasma proteins: transthyretin and retinol-binding protein. Science 268(5213):1039–1041
12. Quadro L, Hamberger L, Colantuoni V, Gottesman ME, Blaner WS (2003) Understanding the physiological role of retinol-binding protein in vitamin A metabolism using transgenic and knockout mouse models. Mol Asp Med 24(6):421–430
13. Quadro L, Hamberger L, Gottesman ME, Colantuoni V, Ramakrishnan R, Blaner WS (2004) Transplacental delivery of retinoid: the role of retinol-binding protein and lipoprotein retinyl ester. Am J Physiol Endocrinol Metab 286(5):E844–E851
14. Morriss-Kay GM, Ward SJ (1999) Retinoids and mammalian development. Int Rev Cytol 188:73–131
15. Sapin V, Ward SJ, Bronner S, Chambon P, Dolle P (1997) Differential expression of transcripts encoding retinoid binding proteins and retinoic acid receptors during placentation of the mouse. Dev Dyn 208(2):199–210
16. Kam RK, Deng Y, Chen Y, Zhao H (2012) Retinoic acid synthesis and functions in early embryonic development. Cell Biosci 2(1):11
17. Nakazawa N, Montedonico S, Takayasu H, Paradisi F, Puri P (2007) Disturbance of retinol transportation causes nitrofen-induced hypoplastic lung. J Pediatr Surg 42(2):345–349
18. Paik J, Vogel S, Quadro L, Piantedosi R, Gottesman M, Lai K, Hamberger L, Vieira Mde M, Vieira Mde M, Blaner WS (2004) Vitamin A: overlapping delivery pathways to tissues from the circulation. J Nutr 134(1):276S–280S
19. Kato Y, Braunstein GD (1991) Retinoic acid stimulates placental hormone secretion by choriocarcinoma cell lines in vitro. Endocrinology 128(1):401–407
20. Nakazawa N, Takayasu H, Montedonico S, Puri P (2007) Altered regulation of retinoic acid synthesis in nitrofen-induced hypoplastic lung. Pediatr Surg Int 23(5):391–396
21. O’Byrne SM, Wongsiriroj N, Libien J, Vogel S, Goldberg IJ, Baehr W, Palczewski K, Blaner WS (2005) Retinoid absorption and storage is impaired in mice lacking lecithin:retinol acyltransferase (LRAT). J Biol Chem 280(42):35647–35657
22. Gallot D, Marceau G, Coste K, Hadden H, Robert-Gnansia E, Laurichesse H, Dechelotte PJ, Labbe A, Dastugue B, Lemery D et al (2005) Congenital diaphragmatic hernia: a retinoid-signaling pathway disruption during lung development? Birth Defects Res A Clin Mol Teratol 73(8):523–531
23. Beurskens LW, Tibboel D, Lindemans J, Duvekot JJ, Cohen-Overbeek TE, Veenma DC, de Klein A, Greer JJ, Steegers-Theunissen RP (2010) Retinol status of newborn infants is associated with congenital diaphragmatic hernia. Pediatrics 126(4):712–720
24. Kutasy B, Gosemann JH, Doi T, Fujiwara N, Friedmacher F, Puri P (2012) Nitrofen interferes with trophoblastic expression of retinol-binding protein and transthyretin during lung morphogenesis in the nitrofen-induced congenital diaphragmatic hernia model. Pediatr Surg Int 28(2):143–148
25. Hosotani K, Kitagawa M (2003) Improved simultaneous determination method of beta-carotene and retinol with saponification in human serum and rat liver. J Chromatogr B Anal Technol Biomed Life Sci 791(1–2):305–313
26. Moulas ANZI, Taitzoglou IA, Tsantarliotou MP, Botsoglou NA (2003) Simultaneous determination of retinoic acid, retinol, and retinyl palmitate in ram plasma by liquid chromatography. J Liq Chromatogr 26:559–572
27. Kutasy B, Gosemann JH, Duess JW, Puri P (2013) Increased trophoblastic apoptosis mediated by neutrophil gelatinase-associated lipocalin (NGAL) activation in the nitrofen model of congenital diaphragmatic hernia. Pediatr Surg Int 29(1):25–31
28. Furukawa S, Hayashi S, Usuda K, Abe M, Hagio S, Ogawa I (2011) Toxicological pathology in the rat placenta. J Toxicol Pathol 24(2):95–111
29. Quadro L, Hamberger L, Gottesman ME, Wang F, Colantuoni V, Blaner WS, Mendelsohn CL (2005) Pathways of vitamin A delivery to the embryo: insights from a new tunable model of embryonic vitamin A deficiency. Endocrinology 146(10):4479–4490
30. Ismadi SD, Olson JA (1982) Dynamics of the fetal distribution and transfer of vitamin A between rat fetuses and their mother. Int J Vitam Nutr Res 52(2):112–119
31. Kim YK, Wassef L, Hamberger L, Piantedosi R, Palczewski K, Blaner WS, Quadro L (2008) Retinyl ester formation by lecithin: retinol acyltransferase is a key regulator of retinoid homeostasis in mouse embryogenesis. J Biol Chem 283(9):5611–5621
32. Wendling O, Chambon P, Mark M (1999) Retinoid X receptors are essential for early mouse development and placentogenesis. Proc Natl Acad Sci USA 96(2):547–551
33. Guilbert TW, Gebb SA, Shannon JM (2000) Lung hypoplasia in the nitrofen model of congenital diaphragmatic hernia occurs early in development. Am J Physiol Lung Cell Mol Physiol 279(6):L1159–L1171
34. Jay PY, Bielinska M, Erlich JM, Mannisto S, Pu WT, Heikinheimo M, Wilson DB (2007) Impaired mesenchymal cell function in Gata4 mutant mice leads to diaphragmatic hernias and primary lung defects. Dev Biol 301(2):602–614
35. Doi T, Hajduk P, Puri P (2009) Upregulation of Slit-2 and Slit-3 gene expressions in the nitrofen-induced hypoplastic lung. J Pediatr Surg 44(11):2092–2095
36. Doi T, Puri P (2009) Up-regulation of Wnt5a gene expression in the nitrofen-induced hypoplastic lung. J Pediatr Surg 44(12):2302–2306
37. Ruttenstock E, Doi T, Dingemann J, Puri P (2011) Prenatal administration of retinoic acid upregulates insulin-like growth factor receptors in the nitrofen-induced hypoplastic lung. Birth Defects Res B Dev Reprod Toxicol 92(2):148–151
38. Kling DE, Cavicchio AJ, Sollinger CA, Schnitzer JJ, Kinane TB, Newburg DS (2010) Nitrofen induces apoptosis independently of retinaldehyde dehydrogenase (RALDH) inhibition. Birth Defects Res B Dev Reprod Toxicol 89(3):223–232
39. Manson JM (1986) Mechanism of nitrofen teratogenesis. Environ Health Perspect 70:137–147
40. Brown TJ, Manson JM (1986) Further characterization of the distribution and metabolism of nitrofen in the pregnant rat. Teratology 34(2):129–139
41. Clugston RD, Zhang W, Greer JJ (2010) Early development of the primordial mammalian diaphragm and cellular mechanisms of nitrofen-induced congenital diaphragmatic hernia. Birth Defects Res A Clin Mol Teratol 88(1):15–24
42. Kutasy B, Friedmacher F, Duess JW, Puri P (2014) Prenatal administration of retinoic acid increases the trophoblastic insulin-like growth factor 2 protein expression in the nitrofen model of congenital diaphragmatic hernia. Pediatr Surg Int 30(2):137–142