In vitro recapitulation of functional microvessels for the study of endothelial shear response, nitric oxide and [Ca2+]i

PLoS ONE

Volumn 10, Issue 5, 2015, Pages

  Li, Xiang ^a   Xu, Sulei ^a   He, Pingnian ^a   Liu, Yuxin ^b  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b West Virginia University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; NITRIC OXIDE; VASCULAR ENDOTHELIAL CADHERIN; CALCIUM;

ARTICLE; CALCIUM CELL LEVEL; CELL JUNCTION; CELL STRUCTURE; CONTROLLED STUDY; FLUORESCENCE IMAGING; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; MICROFLUIDICS; MICROTECHNOLOGY; MICROVASCULATURE; SHEAR FLOW; SHEAR RATE; SHEAR STRESS; UMBILICAL VEIN ENDOTHELIAL CELL; VALIDATION PROCESS; VISCOSITY; BIOSYNTHESIS; CELL PROLIFERATION; CYTOLOGY; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PHYSIOLOGY;

CALCIUM; CELL PROLIFERATION; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MICROFLUIDICS; MICROVESSELS; NITRIC OXIDE;

EID: 84930676562     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0126797     Document Type: Article

References (48)

1. Sackmann EK, Fulton AL, Beebe DJ. The present and future role of microfluidics in biomedical research. Nature. 2014; 507(7491):181-9. doi: 10.1038/nature13118 PMID: 24622198
2. Berthier E, Young EW, Beebe D. Engineers are from PDMS-land, Biologists are from Polystyrenia. Lab on a Chip. 2012; 12(7):1224-37. doi: 10.1039/c2lc20982a PMID: 22318426
3. Li X, Mearns S, Martins-Green M, Liu Y. Procedure for the Development of Multi-depth Circular Cross-sectional Endothelialized Microchannels-on-a-chip. Journal of visualized experiments: JoVE. 2012;(80:):e50771-e. doi: 10.3791/50771 PMID: 24193102
4. Price GM, Wong KH, Truslow JG, Leung AD, Acharya C, Tien J. Effect of mechanical factors on the function of engineered human blood microvessels in microfluidic collagen gels. Biomaterials. 2010; 31(24):6182-9. doi: 10.1016/j.biomaterials.2010.04.041 PMID: 20537705
5. Zheng Y, Chen J, Craven M, Choi NW, Totorica S, Diaz-Santana A, et al. In vitro microvessels for the study of angiogenesis and thrombosis. Proceedings of the National Academy of Sciences of the United States of America. 2012; 109(24):9342-7. doi: 10.1073/pnas.1201240109 PMID: 22645376
6. Tsai M, Kita A, Leach J, Rounsevell R, Huang JN, Moake J, et al. In vitro modeling of the microvascular occlusion and thrombosis that occur in hematologic diseases using microfluidic technology. The Journal of clinical investigation. 2012; 122(1):408-18. doi: 10.1172/JCI58753 PMID: 22156199
7. Bischel LL, Young EW, Mader BR, Beebe DJ. Tubeless microfluidic angiogenesis assay with three-dimensional endothelial-lined microvessels. Biomaterials. 2013; 34(5):1471-7. doi: 10.1016/j.biomaterials.2012.11.005 PMID: 23191982
8. Lamberti G, Prabhakarpandian B, Garson C, Smith A, Pant K, Wang B, et al. Bioinspired Microfluidic Assay for In Vitro Modeling of Leukocyte-Endothelium Interactions. Analytical Chemistry. 2014; 86(16):8344-51. doi: 10.1021/ac5018716 PMID: 25135319
9. Xu S, Zhou X, Yuan D, Xu Y, He P. Caveolin-1 scaffolding domain promotes leukocyte adhesion by reduced basal endothelial nitric oxide-mediated ICAM-1 phosphorylation in rat mesenteric venules. American Journal of Physiology-Heart and Circulatory Physiology. 2013; 305(10):H1484-H93. doi: 10.1152/ajpheart.00382.2013 PMID: 24043249
10. Zhou X, He P. Endothelial [Ca2+]i and caveolin-1 antagonistically regulate eNOS activity and microvessel permeability in rat venules. Cardiovasc Res. 2010; 87(2):340-7. doi: 10.1093/cvr/cvq006 PMID: 20080986
11. Zhou X, He P. Temporal and spatial correlation of platelet-activating factor-induced increases in endothelial [Ca2+]i, nitric oxide, and gap formation in intact venules. American Journal of Physiology-Heart and Circulatory Physiology. 2011; 301(5):H1788-H97. doi: 10.1152/ajpheart.00599.2011 PMID: 21873500
12. Zhu L, He P. Platelet-activating factor increases endothelial [Ca2+]i and NO production in individually perfused intact microvessels. American Journal of Physiology-Heart and Circulatory Physiology. 2005; 288(6):H2869-H77. PMID: 15665052
13. Zadeh MH, Glass CA, Magnussen A, Hancox JC, Bates DO. VEGF-Mediated Elevated Intracellular Calcium and Angiogenesis in Human Microvascular Endothelial Cells In Vitro are Inhibited by Dominant Negative TRPC6. Microcirculation. 2008; 15(7):605-14. doi: 10.1080/10739680802220323 PMID: 18800249
14. Yuan D, He P. Vascular remodeling alters adhesion protein and cytoskeleton reactions to inflammatory stimuli resulting in enhanced permeability increases in rat venules. Journal of Applied Physiology. 2012; 113(7):1110-20. doi: 10.1152/japplphysiol.00102.2012 PMID: 22837164
15. He P, Curry FE. Depolarization modulates endothelial cell calcium influx and microvessel permeability. Am J Physiol. 1991; 261(4 Pt 2):H1246-54. PMID: 1928406
16. He P, Curry FE. Endothelial cell hyperpolarization increases [Ca2+]i and venular microvessel permeability. J Appl Physiol (1985). 1994; 76(6):2288-97. PMID: 7928849
17. He P, Pagakis SN, Curry FE. Measurement of cytoplasmic calcium in single microvessels with increased permeability. Am J Physiol. 1990; 258(5 Pt 2):H1366-74. PMID: 2337172
18. He P, Zhang X, Curry FE. Ca2+ entry through conductive pathway modulates receptor-mediated increase in microvessel permeability. Am J Physiol. 1996; 271(6 Pt 2):H2377-87. PMID: 8997296
19. Munaron L. Intracellular calcium, endothelial cells and angiogenesis. Recent patents on anti-cancer drug discovery. 2006; 1(1):105-19. PMID: 18221030
20. Lee M-J, Thangada S, Claffey KP, Ancellin N, Liu CH, Kluk M, et al. Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate. Cell. 1999; 99(3):301-12. PMID: 10555146
21. Tsai M, Kita A, Leach J, Rounsevell R, Huang JN, Moake J, et al. In vitro modeling of the microvascular occlusion and thrombosis that occur in hematologic diseases using microfluidic technology. The Journal of clinical investigation. 2012; 122(1):408-18. doi: 10.1172/JCI58753 PMID: 22156199
22. Kim S, Lee H, Chung M, Jeon NL. Engineering of functional, perfusable 3D microvascular networks on a chip. Lab Chip. 2013; 13(8):1489-500. doi: 10.1039/c3lc41320a PMID: 23440068
23. D'Amico Oblak T, Root P, Spence DM. Fluorescence monitoring of ATP-stimulated, endothelium-derived nitric oxide production in channels of a poly(dimethylsiloxane)-based microfluidic device. Analytical chemistry. 2006; 78(9):3193-7. PMID: 16643013
24. Huang Z, Li X, Martins-Green M, Liu Y. Microfabrication of cylindrical microfluidic channel networks for microvascular research. Biomedical microdevices. 2012; 14(5):873-83. doi: 10.1007/s10544-012-9667-2 PMID: 22729782
25. Keller HE. Objective Lenses for Confocal Microscopy. In: Pawley JB, editor. Handbook Of Biological Confocal Microscopy: Springer US; 2006. p. 145-61.
26. Zhou X, He P. Improved measurements of intracellular nitric oxide in intact microvessels using 4, 5-diaminofluorescein diacetate. American Journal of Physiology-Heart and Circulatory Physiology. 2011; 301(1):H108-H14. doi: 10.1152/ajpheart.00195.2011 PMID: 21536843
27. Yuan D, Xu S, He P. Enhanced permeability responses to inflammation in streptozotocin-induced diabetic rat venules: Rho-mediated alterations of actin cytoskeleton and VE-cadherin. Am J Physiol Heart Circ Physiol. 2014; 307(1):H44-53. doi: 10.1152/ajpheart.00929.2013 PMID: 24778164
28. Langille BL, Graham JJ, Kim D, Gotlieb AI. Dynamics of shear-induced redistribution of F-actin in endothelial cells in vivo. Arterioscler Thromb. 1991; 11(6):1814-20. PMID: 1931883
29. Sato M, Ohashi T. Biorheological views of endothelial cell responses to mechanical stimuli. Biorheology. 2005; 42(6):421-41. PMID: 16369082
30. Zakrzewicz A, Secomb TW, Pries AR. Angioadaptation: Keeping the Vascular System in Shape. Physiology. 2002; 17(5):197-201.
31. Lipowsky HH, Kovalcheck S, Zweifach BW. The distribution of blood rheological parameters in the microvasculature of cat mesentery. Circulation Research. 1978; 43(5):738-49. PMID: 709740
32. Zhou X, Yuan D, Wang M, He P. H2O2-induced endothelial NO production contributes to vascular cell apoptosis and increased permeability in rat venules. American Journal of Physiology-Heart and Circulatory Physiology. 2013; 304(1):H82-H93. doi: 10.1152/ajpheart.00300.2012 PMID: 23086988
33. Ukropec JA, Hollinger MK, Woolkalis MJ. Regulation of VE-cadherin linkage to the cytoskeleton in endothelial cells exposed to fluid shear stress. Experimental cell research. 2002; 273(2):240-7. PMID: 11822879
34. Tzima E, Irani-Tehrani M, Kiosses WB, Dejana E, Schultz DA, Engelhardt B, et al. A mechanosensory complex that mediates the endothelial cell response to fluid shear stress. Nature. 2005; 437(7057):426-31. PMID: 16163360
35. Nagel T, Resnick N, Atkinson WJ, Dewey CF Jr, Gimbrone MA Jr. Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cells. Journal of Clinical Investigation. 1994; 94(2):885. PMID: 7518844
36. Morawietz H, Talanow R, Szibor M, Rueckschloss U, Schubert A, Bartling B, et al. Regulation of the endothelin system by shear stress in human endothelial cells. The Journal of physiology. 2000; 525(3):761-70. PMID: 10856127
37. Feugier P, Black R, Hunt J, How T. Attachment, morphology and adherence of human endothelial cells to vascular prosthesis materials under the action of shear stress. Biomaterials. 2005; 26(13):1457-66. PMID: 15522747
38. Ando J, Nomura H, Kamiya A. The effect of fluid shear stress on the migration and proliferation of cultured endothelial cells. Microvascular research. 1987; 33(1):62-70. PMID: 3561268
39. Hobson B, Denekamp J. Endothelial proliferation in tumours and normal tissues: continuous labelling studies. British journal of cancer. 1984; 49(4):405-13. PMID: 6201181
40. Curry FE. Modulation of venular microvessel permeability by calcium influx into endothelial cells. FASEB J. 1992; 6(7):2456-66. PMID: 1563597
41. Xu T, Yue W, Li CW, Yao X, Yang M. Microfluidics study of intracellular calcium response to mechanical stimulation on single suspension cells. Lab Chip. 2013; 13(6):1060-9. doi: 10.1039/c3lc40880a PMID: 23403699
42. Kou S, Pan L, van Noort D, Meng G, Wu X, Sun H, et al. A multishear microfluidic device for quantitative analysis of calcium dynamics in osteoblasts. Biochem Biophys Res Commun. 2011; 408(2):350-5. doi: 10.1016/j.bbrc.2011.04.044 PMID: 21514277
43. Sprague RS, Olearczyk JJ, Spence DM, Stephenson AH, Sprung RW, Lonigro AJ. Extracellular ATP signaling in the rabbit lung: erythrocytes as determinants of vascular resistance. Am J Physiol Heart Circ Physiol. 2003; 285(2):H693-700. PMID: 12689860
44. Mannix RJ, Moatter T, Kelley KA, Gerritsen ME. Cellular signaling responses mediated by a novel nucleotide receptor in rabbit microvessel endothelium. Am J Physiol. 1993; 265(2 Pt 2):H675-80. PMID: 8396350
45. Dubyak GR, el-Moatassim C. Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides. Am J Physiol. 1993; 265(3 Pt 1):C577-606. PMID: 8214015
46. Carter TD, Hallam TJ, Cusack NJ, Pearson JD. Regulation of P2y-purinoceptor-mediated prostacyclin release from human endothelial cells by cytoplasmic calcium concentration. Br J Pharmacol. 1988; 95(4):1181-90. PMID: 3064854
47. He P, Curry FE. Differential actions of cAMP on endothelial [Ca2+]i and permeability in microvessels exposed to ATP. American Journal of Physiology - Heart and Circulatory Physiology. 1993; 265(3):H1019-H23.
48. Kojima H, Nakatsubo N, Kikuchi K, Kawahara S, Kirino Y, Nagoshi H, et al. Detection and imaging of nitric oxide with novel fluorescent indicators: diaminofluoresceins. Anal Chem. 1998; 70(13):2446-53. PMID: 9666719