Vascular remodeling alters adhesion protein and cytoskeleton reactions to inflammatory stimuli resulting in enhanced permeability increases in rat venules

Journal of Applied Physiology

Volumn 113, Issue 7, 2012, Pages 1110-1120

  Yuan, Dong ^a   He, Pingnian ^a  

^a WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CADHERIN; CALCIUM; FURA 2; LEUKOCYTE ANTIGEN; THROMBOCYTE ACTIVATING FACTOR; VASCULAR ENDOTHELIAL CADHERIN;

ANIMAL; ARTICLE; CAPILLARY PERMEABILITY; CELL ADHESION; CELL PROLIFERATION; FEMALE; INFLAMMATION; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT; STRESS FIBER; VASCULAR ENDOTHELIUM; VENULE;

ACTINS; ANIMALS; ANTIGENS, CD; CADHERINS; CALCIUM; CAPILLARY PERMEABILITY; CELL ADHESION; CELL PROLIFERATION; ENDOTHELIUM, VASCULAR; FEMALE; FURA-2; INFLAMMATION; PLATELET ACTIVATING FACTOR; RATS; RATS, SPRAGUE-DAWLEY; STRESS FIBERS; VENULES;

EID: 84866995253     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00102.2012     Document Type: Article

References (40)

1. Adamson RH, Curry FE, Adamson G, Liu B, Jiang Y, Aktories K, Barth H, Daigeler A, Golenhofen N, Ness W, Drenckhahn D. Rho and rho kinase modulation of barrier properties: cultured endothelial cells and intact microvessels of rats and mice. J Physiol 539: 295-308, 2002.
2. Adamson RH, Ly JC, Sarai RK, Lenz JF, Altangerel A, Drenckhahn D, Curry FE. Epac/Rap1 pathway regulates microvascular hyperpermeability induced by PAF in rat mesentery. Am J Physiol Heart Circ Physiol 294: H1188-H1196, 2008.
3. Adamson RH, Zeng M, Adamson GN, Lenz JF, Curry FE. PAF-and bradykinin-induced hyperpermeability of rat venules is independent of actin-myosin contraction. Am J Physiol Heart Circ Physiol 285: H406-H417, 2003.
4. Baldwin AL, Thurston G. Changes in endothelial actin cytoskeleton in venules with time after histamine treatment. Am J Physiol Heart Circ Physiol 269: H1528-H1537, 1995.
5. Baluk P, Bowden JJ, Lefevre PM, McDonald DM. Upregulation of substance P receptors in angiogenesis associated with chronic airway inflammation in rats. Am J Physiol Lung Cell Mol Physiol 273: L565-L571, 1997.
6. Canfield AE, Doherty MJ, Wood AC, Farrington C, Ashton B, Begum N, Harvey B, Poole A, Grant ME, Boot-Handford RP. Role of pericytes in vascular calcification: a review. Z Kardiol 89 Suppl 2: 20-27, 2000.
7. Clough G, Michel CC. Quantitative comparisons of hydraulic permeability and endothelial intercellular cleft dimensions in single frog capillaries. J Physiol 405: 563-576, 1988.
8. Curry FE, Zeng M, Adamson RH. Thrombin increases permeability only in venules exposed to inflammatory conditions. Am J Physiol Heart Circ Physiol 285: H2446-H2453, 2003.
9. Curry FR, Adamson RH. Vascular permeability modulation at the cell, microvessel, or whole organ level: towards closing gaps in our knowledge. Cardiovasc Res 87: 218-229, 2010.
10. Curry PE, Huxley VH, Sarelius IH. Techniques in microcirculation: measurement of permeability, pressure and flow. In: Cardiovascular Physiology. Techniques in the Life Sciences. New York: Elsevier, 1983, p. 1-34.
11. Diaz-Flores L, Gutierrez R, Madrid JF, Varela H, Valladares F, Acosta E, Martin-Vasallo P, Diaz-Flores L Jr. Pericytes morphofunction, interactions and pathology in a quiescent and activated mesenchymal cell niche. Histol Histopathol 24: 909-969, 2009.
12. Eyden B. The myofibroblast: an assessment of controversial issues and a definition useful in diagnosis and research. Ultrastruct Pathol 25: 39-50, 2001.
13. Ezaki T, Baluk P, Thurston G, La Barbara A, Woo C, McDonald DM. Time course of endothelial cell proliferation and microvascular remodeling in chronic inflammation. Am J Pathol 158: 2043-2055, 2001.
14. Galis ZS, Khatri JJ. Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly. Circ Res 90: 251-262, 2002.
15. Gandorfer A, Rohleder M, Charteris D, Kampik A, Luthert P. Ultrastructure of vitreomacular traction syndrome associated with persistent hyaloid artery. Eye (Lond) 19: 333-336, 2005.
16. He P. Leucocyte/endothelium interactions and microvessel permeability: coupled or uncoupled? Cardiovasc Res 87: 281-290, 2010.
17. He P, Curry FE. Depolarization modulates endothelial cell calcium influx and microvessel permeability. Am J Physiol Heart Circ Physiol 261: H1246-H1254, 1991.
18. He P, Curry FE. Endothelial cell hyperpolarization increases [Ca2-]i and venular microvessel permeability. J Appl Physiol 76: 2288-2297, 1994.
19. He P, Zhang X, Curry FE. Ca2-entry through conductive pathway modulates receptor-mediated increase in microvessel permeability. Am J Physiol Heart Circ Physiol 271: H2377-H2387, 1996.
20. Hurley JV. Acute inflammation: The effect of concurrent leucocytic emigration and increased vascular permeability on particle retention by the vascular wall. Br J Exp Pathol 45: 627-633, 1964.
21. Jiang Y, Wen K, Zhou X, Schwegler-Berry D, Castranova V, He P. Three-dimensional localization and quantification of PAF-induced gap formation in intact venular microvessels. Am J Physiol Heart Circ Physiol 295: H898-H906, 2008.
22. Kelley C, D'Amore P, Hechtman HB, Shepro D. Vasoactive hormones and cAMP affect pericyte contraction and stress fibres in vitro. J Muscle Res Cell Motil 9: 184-194, 1988.
23. Kendall S, Michel CC. The measurement of permeability in single rat venules using the red cell microperfusion technique. Exp Physiol 80: 359-372, 1995.
24. Khoury J, Langleben D. Platelet-activating factor stimulates lung pericyte growth in vitro. Am J Physiol Lung Cell Mol Physiol 270: L298-L304, 1996.
25. Kim MH, Curry FR, Simon SI. Dynamics of neutrophil extravasation and vascular permeability are uncoupled during aseptic cutaneous wounding. Am J Physiol Cell Physiol 296: C848-C856, 2009.
26. McDonald DM. Endothelial gaps and permeability of venules in rat tracheas exposed to inflammatory stimuli. Am J Physiol Lung Cell Mol Physiol 266: L61-L83, 1994.
27. Michel CC, Curry FE. Microvascular permeability. Physiol Rev 79: 703-761, 1999.
28. Shen Q, Rigor RR, Pivetti CD, Wu MH, Yuan SY. Myosin light chain kinase in microvascular endothelial barrier function. Cardiovasc Res 87: 272-280, 2010.
29. Sims DE, Miller FN, Donald A, Perricone MA. Ultrastructure of pericytes in early stages of histamine-induced inflammation. J Morphol 206: 333-342, 1990.
30. Steed MM, Tyagi SC. Mechanisms of cardiovascular remodeling in hyperhomocysteinemia. Antioxid Redox Signal 15: 1927-1943, 2011.
31. Thurston G, Murphy TJ, Baluk P, Lindsey JR, McDonald DM. Angiogenesis in mice with chronic airway inflammation: strain-dependent differences. Am J Pathol 153: 1099-1112, 1998.
32. Tomasek JJ, Gabbiani G, Hinz B, Chaponnier C, Brown RA. Myofibroblasts and mechano-regulation of connective tissue remodelling. Nat Rev Mol Cell Biol 3: 349-363, 2002.
33. Valeski JE, Baldwin AL. Role of the actin cytoskeleton in regulating endothelial permeability in venules. Microcirculation 10: 411-420, 2003.
34. Waschke J, Drenckhahn D, Adamson RH, Curry FE. Role of adhesion and contraction in Rac 1-regulated endothelial barrier function in vivo and in vitro. Am J Physiol Heart Circ Physiol 287: H704-H711, 2004.
35. Wysolmerski RB, Lagunoff D. Involvement of myosin light-chain kinase in endothelial cell retraction. Proc Natl Acad Sci USA 87: 16-20, 1990.
36. Yuan SY, Wu MH, Ustinova EE, Guo M, Tinsley JH, De Lanerolle P, Xu W. Myosin light chain phosphorylation in neutrophil-stimulated coronary microvascular leakage. Circ Res 90: 1214-1221, 2002.
37. Yuan Y, Huang Q, Wu HM. Myosin light chain phosphorylation: modulation of basal and agonist-stimulated venular permeability. Am J Physiol Heart Circ Physiol 272: H1437-H1443, 1997.
38. Zeng M, Zhang H, Lowell C, He P. Tumor necrosis factor-alpha-induced leukocyte adhesion and microvessel permeability. Am J Physiol Heart Circ Physiol 283: H2420-H2430, 2002.
39. Zhu L, He P. fMLP-stimulated release of reactive oxygen species from adherent leukocytes increases microvessel permeability. Am J Physiol Heart Circ Physiol 290: H365-H372, 2006.
40. Zhu L, He P. Platelet-activating factor increases endothelial [Ca2-]i and NO production in individually perfused intact microvessels. Am J Physiol Heart Circ Physiol 288: H2869-H2877, 2005.