The longitudinal transcriptomic response of the substantia nigra to intrastriatal 6-hydroxydopamine reveals significant upregulation of regeneration-associated genes

PLoS ONE

Volumn 10, Issue 5, 2015, Pages

  Kanaan, Nicholas M ^a,b,c   Collier, Timothy J ^a,b,c   Cole Strauss, Allyson ^a,b   Grabinski, Tessa ^a   Mattingly, Zachary R ^a   Winn, Mary E ^d   Steece Collier, Kathy ^a,b,c   Sortwell, Caryl E ^a,b,c   Manfredsson, Fredric P ^a   Lipton, Jack W ^a,b,c  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c Hauenstein Neuroscience Center   (United States)

^d VAN ANDEL RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MATRIX METALLOPROTEINASE 19; OXIDOPAMINE; TRANSCRIPTION FACTOR SOX11; MESSENGER RNA; TRANSCRIPTOME;

ANIMAL CELL; ARTICLE; ATF3 GENE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; ECEL1 GENE; GADD45A GENE; GENE; GENE CLUSTER; GENE EXPRESSION; GENE IDENTIFICATION; GENETIC TRANSCRIPTION; GPNMB GENE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LIFR GENE; MALE; MMP19 GENE; NONHUMAN; POLYMERASE CHAIN REACTION; RAB15 GENE; RAT; SEMA3C GENE; SOX11 GENE; SPRR1A GENE; SRGAP1 GENE; SUBSTANTIA NIGRA; TGFB1 GENE; TRANSCRIPTOMICS; TRIB3 GENE; UPREGULATION; ANIMAL; CLUSTER ANALYSIS; CORPUS STRIATUM; GENE REGULATORY NETWORK; GENETICS; METABOLISM; NERVE REGENERATION; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REPRODUCIBILITY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

RATTUS NORVEGICUS;

ANIMALS; CLUSTER ANALYSIS; CORPUS STRIATUM; GENE REGULATORY NETWORKS; MALE; NERVE REGENERATION; OXIDOPAMINE; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; REPRODUCIBILITY OF RESULTS; RNA, MESSENGER; SIGNAL TRANSDUCTION; SUBSTANTIA NIGRA; TRANSCRIPTOME; UP-REGULATION;

EID: 84930665788     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0127768     Document Type: Article

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