Preparation of silica nanoparticles loaded with nootropics and their in vivo permeation through blood-brain barrier

BioMed Research International

Volumn 2015, Issue , 2015, Pages

  Jampilek, Josef ^a   Zaruba, Kamil ^b   Oravec, Michal ^c   Kunes, Martin ^a   Babula, Petr ^a   Ulbrich, Pavel ^b   Brezaniova, Ingrid ^b   Opatrilova, Radka ^a   Triska, Jan ^c   Suchy, Pavel ^a  

^a UNIVERSITY OF VETERINARY AND PHARMACEUTICAL SCIENCES   (Czech Republic)

^b INSTITUTE OF CHEMICAL TECHNOLOGY   (Czech Republic)

^c Global Change Research Centre AS CR   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG CARRIER; PENTOXIFYLLINE; PIRACETAM; PYRIDOXINE; SILICA NANOPARTICLE; NANOPARTICLE; NOOTROPIC AGENT; SILICON DIOXIDE;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN PERFUSION; BRAIN TISSUE; CARDIOVASCULAR SYSTEM; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG TRANSPORT; FEMALE; FINITE ELEMENT ANALYSIS; IN VIVO STUDY; MASS SPECTROMETRY; MEMBRANE TRANSPORT; NONHUMAN; PARTICLE SIZE; RAT; TRANSMISSION ELECTRON MICROSCOPY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRAVIOLET SPECTROSCOPY; ANIMAL; CHEMISTRY; MALE; METABOLISM; WISTAR RAT;

RATTUS;

ANIMALS; BLOOD-BRAIN BARRIER; DRUG CARRIERS; MALE; NANOPARTICLES; NOOTROPIC AGENTS; RATS; RATS, WISTAR; SILICON DIOXIDE;

EID: 84930654273     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2015/812673     Document Type: Article

References (34)

1. H. J. Roth and H. Fenner, Arzneistofe, Deutscher Apotheker, Stuttgart, Germany, 3rd edition, 2000.
2. D. J. Abraham and D. P. Rotella, Burger's Medicinal Chemistry, Drug Discovery and Development, Wiley, New York, NY, USA, 7th edition, 2010.
3. M. S. Alavijeh, M. Chishty, M. Z. Qaiser, and A. M. Palmer, "Drug metabolism and pharmacokinetics, the blood-brain barrier, and central nervous system drug discovery," NeuroRx, vol. 2, no. 4, pp. 554-571, 2005.
4. N. J. Abbott, A. A. K. Patabendige, D. E. M. Dolman, S. R. Yusof, and D. J. Begley, "Structure and function of the blood-brain barrier," Neurobiology of Disease, vol. 37, no. 1, pp. 13-25, 2010.
5. C. Passeleu-Le Bourdonnec, P.-A. Carrupt, J. M. Scherrmann, and S. Martel, "Methodologies to assess drug permeation through the blood-brain barrier for pharmaceutical research," Pharmaceutical Research, vol. 30, no. 11, pp. 2729-2756, 2013.
6. N. J. Abbott, L. Rönnbäck, and E. Hansson, "Astrocyte-endo-thelial interactions at the blood-brain barrier," Nature Reviews Neuroscience, vol. 7, no. 1, pp. 41-53, 2006.
7. C.-T. Lu, Y.-Z. Zhao, H. L. Wong, J. Cai, L. Peng, and X.-Q. Tian, "Current approaches to enhance CNS delivery of drugs across the brain barriers," International Journal of Nanomedicine, vol. 9, no. 1, pp. 2241-2257, 2014.
8. Z. Yang, Z. W. Liu, R. P. Allaker et al., "A review of nanoparticle functionality and toxicity on the central nervous system," The Journal of the Royal Society Interface, vol. 7, supplement 4, pp. S411-S422, 2010.
9. H. L. Wong, X. Y. Wu, and R. Bendayan, "Nanotechnological advances for the delivery of CNS therapeutics," Advanced Drug Delivery Reviews, vol. 64, no. 7, pp. 686-700, 2012.
10. S. Bhaskar, F. Tian, T. Stoeger et al., "Multifunctional Nanocarri-ers for diagnostics, drug delivery and targeted treatment across blood-brain barrier: Perspectives on tracking and neuroimag-ing," Particle and Fibre Toxicology, vol. 7, article 3, 25 pages, 2010.
11. M. Simko and M.-O. Mattsson, "Interactions between nano-sized materials and the brain," Current Medicinal Chemistry, vol. 21, no. 37, pp. 4200-4214, 2014.
12. A. Bitar, N. M. Ahmad, H. Fessi, and A. Elaissari, "Silica-based nanoparticles for biomedical applications," Drug Discovery Today, vol. 17, no. 19-20, pp. 1147-1154, 2012.
13. H. Nehof, N. N. Parayath, L. Domanovitch, S. Taurin, and K. Greish, "Nanomedicine for drug targeting: strategies beyond the enhanced permeability and retention efect," International Journal of Nanomedicine, vol. 9, no. 1, pp. 2539-2555, 2014.
14. Y. T. Liao, C. H. Liu, J. Yu, and K. C. W. Wu, "Liver cancer cells: targeting and prolonged-release drug carriers consisting of mesoporous silica nanoparticles and alginate microspheres," International Journal of Nanomedicine, vol. 9, pp. 2767-2778, 2014.
15. V. Marzaioli, J. A. Aguilar-Pimentel, I. Weichenmeier et al., "Surface modifcations of silica nanoparticles are crucial for their inert versus proinfammatory and immunomodulatory properties," International Journal of Nanomedicine, vol. 9, pp. 2815-2832, 2014.
16. L. Tang and J. Cheng, "Nonporous silica nanoparticles for nanomedicine application," Nano Today, vol. 8, no. 3, pp. 290-312, 2013.
17. E. Vaculikova, D. Placha, and J. Jampílek, "Toxicology of drug nanocarriers," Chemické Listy, vol. 109, no. 5, 2015.
18. L. Costantino, G. Tosi, B. Ruozi, L. Bondioli, M. A. Vandelli, and F. Forni, "Colloidal systems for CNS drug delivery," in Progress in Brain Research Nanoneuroscience and Nanoneuropharmacol-ogy, S. S. Hari, Ed., pp. 35-69, Elsevier, 2009.
19. Y. Wang, Q. Zhao, N. Han et al., "Mesoporous silica nanopar-ticles in drug delivery and biomedical applications," Nano-medicine: Nanotechnology, Biology and Medicine, vol. 11, no. 2, pp. 313-327, 2015.
20. D. Liu, B. Lin, W. Shao, Z. Zhu, T. Ji, and C. Yang, "In vitro and in vivo studies on the transport of PEGylated silica nanoparticles across the blood-brain barrier," ACS Applied Materials and Interfaces, vol. 6, no. 3, pp. 2131-2136, 2014.
21. S. Ku, F. Yan, Y. Wang, Y. Sun, N. Yang, and L. Ye, "The blood-brain barrier penetration and distribution of PEGylated fuorescein-doped magnetic silica nanoparticles in rat brain," Biochemical and Biophysical Research Communications, vol. 394, no. 4, pp. 871-876, 2010.
22. H. Xu, F. Yan, E.E. Monson, and R. Kopelman, "Room-temperature preparation and characterization of poly(ethylene glycol)-coated silica nanoparticles for biomedical applications," Journal of Biomedical Materials Research: Part A, vol. 66, no. 4, pp. 870-879, 2003.
23. W. Stöber, A. Fink, and E. Bohn, "Controlled growth of monodisperse silica spheres in the micron size range," Journal of Colloid And Interface Science, vol. 26, no. 1, pp. 62-69, 1968.
24. H. Xu, J. W. Aylott, R. Kopelman, T. J. Miller, and M. A. Philbert, "A real-time ratiometric method for the determination of molecular oxygen inside living cells using sol-gel-based spherical optical nanosensors with applications to rat C6 glioma," Analytical Chemistry, vol. 73, no. 17, pp. 4124-4133, 2001.
25. W. Tang, H. Xu, R. Kopelman, and M. A. Philbert, "Photody-namic characterization and in vitro application of methylene blue-containing nanoparticle platforms," Photochemistry and Photobiology, vol. 81, no. 2, pp. 242-249, 2005.
26. Y. Takasato, S. I. Rapoport, and Q. R. Smith, "An in situ brain perfusion technique to study cerebrovascular transport in the rat," The American Journal of Physiology, vol. 247, no. 3, pp. H484-H493, 1984.
27. D. D. Allen, J. Oki, and Q. R. Smith, "An update on the in situ brain perfusion technique: simple, faster, better," Pharmacological Research, vol. 14, p. s337, 1997.
28. R. Q. Smith and D. D. Allen, "In situ brain perfusion technique," in Methods in Molecular Medicine-The Blood-Brain Barrier: Biology and Research Protocols, S. Nag, Ed., vol. 89, pp. 209-218, Humana Press, Totowa, NJ, USA, 2003.
29. M. Kuněs, J. Květina, P. Kubant, J. Maláková, V. Herout, and Z. Svoboda, "Infuence of methotrexate and L-carnitine on transintestinal transport of model substances (the rat small intestine in situ perfusion)," Chemicke Listy, vol. 101, no. 14, pp. s209-s211, 2007.
30. M. Kuněs, J. Květina, Z. Svoboda, and V. Herout, "Study of the mechanisms of intestinal absorption of xenobiotics using in situ perfusion of rat intestine," Biologia, vol. 60, no. 17, pp. s89-s92, 2005.
31. K. Shimizu, Y. del Amo, M. A. Brzezinski, G. D. Stucky, and D. E. Morse, "A novel fuorescent silica tracer for biological silicifca-tion studies," Chemistry and Biology, vol. 8, no. 11, pp. 1051-1060, 2001.
32. S. J. Swanson, P. C. Bethke, and R. L. Jones, "Barley aleurone cells contain two types of vacuoles: characterization of lytic organelles by use of fuorescent probes," Plant Cell, vol. 10, no. 5, pp. 685-698, 1998.
33. P. Znachor, J. Nedoma, and P. Rychtecký, "Kinetics of glucose stimulatory efect on silica deposition and growth of natural populations of Fragilaria crotonensis," Phycological Research, vol. 59, no. 2, pp. 123-128, 2011.
34. V. R. Meyer, "Adsorption chromatography: normal-phase," in Chromatography Practical High-Performance Liquid Chro-matography, pp. 159-172, John Wiley & Sons, Chichester, UK, 5th edition, 2010.