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Volumn 55, Issue , 2015, Pages 471-481

Synthesis and characterization of silane coated magnetic nanoparticles/glycidylmethacrylate-grafted-maleated cyclodextrin composite hydrogel as a drug carrier for the controlled delivery of 5-fluorouracil

Author keywords

5 FU 5 Fluorouracil; Abbreviations DDS Drug delivery system; AIBN a a azobisisobutyronitrile; DLE Drug loading efficiency; DLS Diffuse light scattering; DMEM Dulbecco's modified minimal essential media; DMF Dimethyl formamide; EE Encapsulation Efficiency; EGDMA Ethyleneglycoldimethacrylate; FCS Fetal calf serum; FT IR Fourier transform infrared spectroscopy; GMA Glycidylmethacrylate; Ms< inf> Saturation magnetization values; MACD Maleated cyclodextrin; MAH Maleic anhydride; MNP Magnetic nanoparticles; MPTMS 3 methacryloxypropyltrimethoxy silane; MTT assay 3 4 5 dimethylthiazol 2 yl 2 5 diphenyl tetrazolium bromide; PBS Phosphate buffer solution; SEM Scanning electron microscopy; XRD X ray diffraction; CD cyclodextrin

Indexed keywords

BIOCOMPATIBILITY; CYCLODEXTRINS; CYTOTOXICITY; DIFFUSION IN SOLIDS; DRUG INTERACTIONS; DRUG PRODUCTS; DYNAMIC LIGHT SCATTERING; EFFICIENCY; ENCAPSULATION; FOURIER TRANSFORM INFRARED SPECTROSCOPY; LIGHT SCATTERING; MAGNETISM; NANOMAGNETICS; NANOPARTICLES; SATURATION MAGNETIZATION; SCANNING ELECTRON MICROSCOPY; SYNTHESIS (CHEMICAL); X RAY DIFFRACTION;

EID: 84930645196     PISSN: 09284931     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.msec.2015.05.068     Document Type: Article
Times cited : (49)

References (39)
  • 1
    • 55249095515 scopus 로고    scopus 로고
    • Novel strategies to improve the anticancer action of 5-fluorouracil by using drug delivery systems
    • L.A. Jose Novel strategies to improve the anticancer action of 5-fluorouracil by using drug delivery systems Molecules 13 2008 2340 2369
    • (2008) Molecules , vol.13 , pp. 2340-2369
    • Jose, L.A.1
  • 2
    • 84860911018 scopus 로고    scopus 로고
    • Release behavior and cytotoxicity of poly(vinyl alcohol)/chitosan blend microspheres containing 2,4-dihydroxy-5-fluropyrimidine
    • X. Lizhi, and H. Zegiang Release behavior and cytotoxicity of poly(vinyl alcohol)/chitosan blend microspheres containing 2,4-dihydroxy-5-fluropyrimidine Polym. Plast. Technol. Eng. 51 2012 729 733
    • (2012) Polym. Plast. Technol. Eng. , vol.51 , pp. 729-733
    • Lizhi, X.1    Zegiang, H.2
  • 3
    • 67349118457 scopus 로고    scopus 로고
    • PH-sensitive starch hydrogels via free radical graft copolymerization, synthesis and properties
    • M.R. Saboktakin, A. Maharramov, and M.A. Ramazanov pH-sensitive starch hydrogels via free radical graft copolymerization, synthesis and properties Carbohydr. Polym. 77 2009 634 638
    • (2009) Carbohydr. Polym. , vol.77 , pp. 634-638
    • Saboktakin, M.R.1    Maharramov, A.2    Ramazanov, M.A.3
  • 4
    • 0017983349 scopus 로고
    • Magnetic guidance of drug carrying microspheres
    • A. Senyei, K. Widder, and C. Czerlinski Magnetic guidance of drug carrying microspheres J. Appl. Phys. 49 1978 3578 3583
    • (1978) J. Appl. Phys. , vol.49 , pp. 3578-3583
    • Senyei, A.1    Widder, K.2    Czerlinski, C.3
  • 6
    • 34247179477 scopus 로고    scopus 로고
    • Magnetic nanoparticles: Synthesis, protection, functionalization and application
    • L. An-Hui, E.L. Salabas, and S. Ferdi Magnetic nanoparticles: synthesis, protection, functionalization and application Angew. Chem. Int. Ed. 46 2007 1222 1244
    • (2007) Angew. Chem. Int. Ed. , vol.46 , pp. 1222-1244
    • An-Hui, L.1    Salabas, E.L.2    Ferdi, S.3
  • 7
    • 64249171321 scopus 로고    scopus 로고
    • Functionalization of magnetic nanoparticles with 3-aminopropyl silane
    • C. Stanislav, M. Darko, and D. Miha Functionalization of magnetic nanoparticles with 3-aminopropyl silane J. Magn. Magn. Mater. 321 2009 1346 1350
    • (2009) J. Magn. Magn. Mater. , vol.321 , pp. 1346-1350
    • Stanislav, C.1    Darko, M.2    Miha, D.3
  • 8
    • 84904548294 scopus 로고    scopus 로고
    • Esterases immobilized on amino silane modified magnetic nanoparticles as a catalyst for biotransformation reactions
    • A. Deepthy, M. Abraham, and K.S. Rajeev Esterases immobilized on amino silane modified magnetic nanoparticles as a catalyst for biotransformation reactions Bioresour. Technol. 167 2014 547 550 10.1016/j.biortech.2014.15.110
    • (2014) Bioresour. Technol. , vol.167 , pp. 547-550
    • Deepthy, A.1    Abraham, M.2    Rajeev, K.S.3
  • 9
    • 62949238907 scopus 로고    scopus 로고
    • Chitosan-graft-β-cyclodextrin scaffolds with controlled drug release capability for tissue engineering applications
    • M. Prabaharan, and R. Jayakumar Chitosan-graft-β-cyclodextrin scaffolds with controlled drug release capability for tissue engineering applications Int. J. Biol. Macromol. 44 2009 320 325
    • (2009) Int. J. Biol. Macromol. , vol.44 , pp. 320-325
    • Prabaharan, M.1    Jayakumar, R.2
  • 10
    • 78650522223 scopus 로고    scopus 로고
    • A novel route for the preparation of thermally sensitive core-shell magnetic nanoparticles
    • S.Y. Park, O. Muhammad, and H. Sajjad A novel route for the preparation of thermally sensitive core-shell magnetic nanoparticles Polymer 52 2011 91 97
    • (2011) Polymer , vol.52 , pp. 91-97
    • Park, S.Y.1    Muhammad, O.2    Sajjad, H.3
  • 11
    • 79956201658 scopus 로고    scopus 로고
    • Synergistic performance of cyclodextrin-agar hydrogels for ciprofloxacin delivery and antimicrobial effect
    • F.B. Blanco, V.M. Lopez, A. Concheiro, and L.C. Alvarez Synergistic performance of cyclodextrin-agar hydrogels for ciprofloxacin delivery and antimicrobial effect Carbohydr. Polym. 85 2011 765 774
    • (2011) Carbohydr. Polym. , vol.85 , pp. 765-774
    • Blanco, F.B.1    Lopez, V.M.2    Concheiro, A.3    Alvarez, L.C.4
  • 12
    • 84874943447 scopus 로고    scopus 로고
    • Chitosan-graft-β-cyclodextrin nanoparticles as a carrier for controlled drug release
    • Z. Yuan, Y. Ye, F. Gao, H. Yuan, M. Lan, K. Lou, and W. Wang Chitosan-graft-β-cyclodextrin nanoparticles as a carrier for controlled drug release Int. J. Pharm. 446 2013 191 1998
    • (2013) Int. J. Pharm. , vol.446 , pp. 191-1998
    • Yuan, Z.1    Ye, Y.2    Gao, F.3    Yuan, H.4    Lan, M.5    Lou, K.6    Wang, W.7
  • 14
    • 84891601173 scopus 로고    scopus 로고
    • Cytocompatible injectable carboxymethyl chitosan/N-isopropyl acrylamide hydrogels for localized drug delivery
    • L. Zhang, L. Wang, B. Guo, and P.X. Ma Cytocompatible injectable carboxymethyl chitosan/N-isopropyl acrylamide hydrogels for localized drug delivery Carbohydr. Polym. 103 2014 110 118
    • (2014) Carbohydr. Polym. , vol.103 , pp. 110-118
    • Zhang, L.1    Wang, L.2    Guo, B.3    Ma, P.X.4
  • 15
    • 84891950382 scopus 로고    scopus 로고
    • Grafting of GMA and some comonomers onto chitosan for controlled release of diclofenac sodium
    • R.K. Sharma, Lalitha, A.P. Singh, and G.S. Chauhan Grafting of GMA and some comonomers onto chitosan for controlled release of diclofenac sodium Int. J. Biol. Macromol. 64 2014 368 376
    • (2014) Int. J. Biol. Macromol. , vol.64 , pp. 368-376
    • Sharma, R.K.1    Lalitha2    Singh, A.P.3    Chauhan, G.S.4
  • 16
  • 17
    • 78649998197 scopus 로고    scopus 로고
    • Adsorption and desorption of l-phenylalanine on nano-sized magnetic particles
    • N. Balaji, N. Anantharaman, M.S. Uddin, and M.N.K.M. Beegums Adsorption and desorption of l-phenylalanine on nano-sized magnetic particles J. Eng. Appl. Sci. 8 2009 1819 1823
    • (2009) J. Eng. Appl. Sci. , vol.8 , pp. 1819-1823
    • Balaji, N.1    Anantharaman, N.2    Uddin, M.S.3    Beegums, M.N.K.M.4
  • 19
    • 78650522223 scopus 로고    scopus 로고
    • A novel route for the preparation of thermally sensitive core-shell magnetic nano particles
    • O. Muhammad, H. Sajjad, and P. Soo-Young A novel route for the preparation of thermally sensitive core-shell magnetic nano particles Polymer 52 2011 91 97
    • (2011) Polymer , vol.52 , pp. 91-97
    • Muhammad, O.1    Sajjad, H.2    Soo-Young, P.3
  • 20
    • 65949089151 scopus 로고    scopus 로고
    • Reaction of glycidyl methacrylate at the hydroxyl and carboxylic groups of poly(vinyl alcohol) and poly(acrylic acid). Is this reaction mechanism still unclear?
    • A.V. Reis, A.R. Fajardo, I.T.A. Schuquel, M.R. Guilherme, G.J. Vidotti, A.F. Rubira, and E.C. Muniz Reaction of glycidyl methacrylate at the hydroxyl and carboxylic groups of poly(vinyl alcohol) and poly(acrylic acid). Is this reaction mechanism still unclear? J. Org. Chem. 74 2009 3750 3757
    • (2009) J. Org. Chem. , vol.74 , pp. 3750-3757
    • Reis, A.V.1    Fajardo, A.R.2    Schuquel, I.T.A.3    Guilherme, M.R.4    Vidotti, G.J.5    Rubira, A.F.6    Muniz, E.C.7
  • 21
    • 0028474187 scopus 로고
    • Influence of degree of cross-linking on 5-fluorouracil release from poly(2-hydroxyethyl methacrylate) hydrogels
    • O. Garcia, R.M.M.D. Trigo Blanco, and J.M. Teijon Influence of degree of cross-linking on 5-fluorouracil release from poly(2-hydroxyethyl methacrylate) hydrogels Biomaterials 15 1994 689 694
    • (1994) Biomaterials , vol.15 , pp. 689-694
    • Garcia, O.1    Trigo Blanco, R.M.M.D.2    Teijon, J.M.3
  • 22
    • 84867821318 scopus 로고    scopus 로고
    • Novel thermo/pH sensitive nanogels composed from poly(N-vinyl caprolactum) for controlled release of anticancer drug
    • K.M. Rao, B. Mallikarjuna, K.S.V.K. Rao, S. Siraj, K.C. Rao, and M.C.S. Subha Novel thermo/pH sensitive nanogels composed from poly(N-vinyl caprolactum) for controlled release of anticancer drug Colloids Surf. B: Biointerfaces 102 2013 891 897
    • (2013) Colloids Surf. B: Biointerfaces , vol.102 , pp. 891-897
    • Rao, K.M.1    Mallikarjuna, B.2    Rao, K.S.V.K.3    Siraj, S.4    Rao, K.C.5    Subha, M.C.S.6
  • 24
    • 73649113148 scopus 로고    scopus 로고
    • Preparation and characterization of magnetic nanoparticles coated with polyethylene glycol
    • L.T.M. Hoa, T.T. Dung, T.M. Danh, N.H. Duc, and D.M. Chien Preparation and characterization of magnetic nanoparticles coated with polyethylene glycol J. Phys. Conf. Ser. 187 2009 012048 10.1088/1742-6596/187/1/012048
    • (2009) J. Phys. Conf. Ser. , vol.187 , pp. 012048
    • Hoa, L.T.M.1    Dung, T.T.2    Danh, T.M.3    Duc, N.H.4    Chien, D.M.5
  • 25
    • 79955571364 scopus 로고    scopus 로고
    • Synthesis and characterization of multifunctional chitosan-MnFe2O4 nanoparticles for magnetic hyperthermia and drug delivery
    • D. Kin, D.T. Nikles, and C.S. Brazel Synthesis and characterization of multifunctional chitosan-MnFe2O4 nanoparticles for magnetic hyperthermia and drug delivery Materials 3 2010 4051 4065
    • (2010) Materials , vol.3 , pp. 4051-4065
    • Kin, D.1    Nikles, D.T.2    Brazel, C.S.3
  • 26
    • 67549148321 scopus 로고    scopus 로고
    • Fabrication of cyclodextrin-functionalized supermagnetic Fe3O4/amino-silane core shell nanoparticles via layer by layer method
    • H. Cao, J. He, L. Deng, and X. Gao Fabrication of cyclodextrin-functionalized supermagnetic Fe3O4/amino-silane core shell nanoparticles via layer by layer method Appl. Surf. Sci. 255 2009 7974 7980
    • (2009) Appl. Surf. Sci. , vol.255 , pp. 7974-7980
    • Cao, H.1    He, J.2    Deng, L.3    Gao, X.4
  • 27
    • 84866984651 scopus 로고    scopus 로고
    • Synthesis and characterization of maleated cyclodextrin-grafted-silylated montmorillonite for the controlled release and colon specific delivery of tetracycline hydrochloride
    • T.S. Anirudhan, S. Sandeep, and P.L. Divya Synthesis and characterization of maleated cyclodextrin-grafted-silylated montmorillonite for the controlled release and colon specific delivery of tetracycline hydrochloride RSC Adv. 2 2012 9555 9564
    • (2012) RSC Adv. , vol.2 , pp. 9555-9564
    • Anirudhan, T.S.1    Sandeep, S.2    Divya, P.L.3
  • 28
    • 84898933519 scopus 로고    scopus 로고
    • Synthesis and characterization of chitosan based multilayer and pH sensitive co-polymeric system for the targeted delivery of 5-fluorouracil, an in vitro study
    • T.S. Anirudhan, Binusreejayan, and S.R. Rejeena Synthesis and characterization of chitosan based multilayer and pH sensitive co-polymeric system for the targeted delivery of 5-fluorouracil, an in vitro study Int. J. Polym. Mater. Polym. Biomater. 63 2014 539 548
    • (2014) Int. J. Polym. Mater. Polym. Biomater. , vol.63 , pp. 539-548
    • Anirudhan, T.S.1    Binusreejayan2    Rejeena, S.R.3
  • 30
    • 84886363607 scopus 로고    scopus 로고
    • Selective recognition of 2,4,6-trichlorophenol by molecularly imprinted polymers based on magnetic halloysite-nanotubes composites
    • J. Pan, H. Yao, L. Xu, H. Ou, P. Huo, X. Li, and Y. Yang Selective recognition of 2,4,6-trichlorophenol by molecularly imprinted polymers based on magnetic halloysite-nanotubes composites J. Phys. Chem. 21 2011 183 190
    • (2011) J. Phys. Chem. , vol.21 , pp. 183-190
    • Pan, J.1    Yao, H.2    Xu, L.3    Ou, H.4    Huo, P.5    Li, X.6    Yang, Y.7
  • 31
    • 0043072751 scopus 로고    scopus 로고
    • Preparation of 5-fluorouracil-loaded poly(L-lactide-co-glycolide) wafer and evaluation of in vitro release behavior
    • J.S. Lee, G.S. Chae, T.K. An, and G. Khang Preparation of 5-fluorouracil-loaded poly(L-lactide-co-glycolide) wafer and evaluation of in vitro release behavior Macromol. Res. 11 2003 183 188
    • (2003) Macromol. Res. , vol.11 , pp. 183-188
    • Lee, J.S.1    Chae, G.S.2    An, T.K.3    Khang, G.4
  • 32
    • 63549114827 scopus 로고    scopus 로고
    • Chitosan-graft poly(p-dioxanone) copolymers: Preparation, characterization and properties
    • X.L. Wang, Y. Huang, and J. Zhu Chitosan-graft poly(p-dioxanone) copolymers: preparation, characterization and properties Carbohydr. Res. 344 2009 801 807
    • (2009) Carbohydr. Res. , vol.344 , pp. 801-807
    • Wang, X.L.1    Huang, Y.2    Zhu, J.3
  • 34
    • 84870541534 scopus 로고    scopus 로고
    • Swelling characteristics of konjac glucomannan superadsorbent synthesized by radiation-induced graft co-polymerization
    • J. Wu, X. Deng, and X. Lin Swelling characteristics of konjac glucomannan superadsorbent synthesized by radiation-induced graft co-polymerization Radiat. Phys. Chem. 83 2013 90 97
    • (2013) Radiat. Phys. Chem. , vol.83 , pp. 90-97
    • Wu, J.1    Deng, X.2    Lin, X.3
  • 35
    • 77951831519 scopus 로고    scopus 로고
    • Novel chitosan based pH sensitive micro-networks for the controlled release of 5-FU
    • K.S.V.K. Rao, K.M. Rao, and P.V.N. Kumar Novel chitosan based pH sensitive micro-networks for the controlled release of 5-FU Iran. Polym. J. 19 2010 265 276
    • (2010) Iran. Polym. J. , vol.19 , pp. 265-276
    • Rao, K.S.V.K.1    Rao, K.M.2    Kumar, P.V.N.3
  • 36
    • 15344340854 scopus 로고    scopus 로고
    • Antibiotics: Isolation and characterization
    • 8th edn Prestice-hall international Inc. New Jersey
    • M.T. Madigan, J.M. Martiko, and J. Parker Antibiotics: isolation and characterization Brook Biology of Microorganisms 8th edn 1997 Prestice-hall international Inc. New Jersey
    • (1997) Brook Biology of Microorganisms
    • Madigan, M.T.1    Martiko, J.M.2    Parker, J.3


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