-
1
-
-
81255143017
-
Arterial thrombosis: Insidious, unpredictable and deadly
-
Jackson SP. Arterial thrombosis: insidious, unpredictable and deadly. Nat Med. 2011;17:1423–1436
-
(2011)
Nat Med
, vol.17
, pp. 1423-1436
-
-
Jackson, S.P.1
-
3
-
-
0034978187
-
Molecular identification and characterization of the platelet ADP receptor targeted by thienopyridine antithrombotic drugs
-
Foster CJ, Prosser DM, Agans JM, et al. Molecular identification and characterization of the platelet ADP receptor targeted by thienopyridine antithrombotic drugs. J Clin Invest. 2001;107:1591–1598
-
(2001)
J Clin Invest
, vol.107
, pp. 1591-1598
-
-
Foster, C.J.1
Prosser, D.M.2
Agans, J.M.3
-
4
-
-
0035899289
-
Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
-
Yusuf S, Zhao F, Mehta SR, Chrolavicius S, Tognoni G, Fox KK. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med. 2001;345: 494–502
-
(2001)
N Engl J Med
, vol.345
, pp. 494-502
-
-
Yusuf, S.1
Zhao, F.2
Mehta, S.R.3
Chrolavicius, S.4
Tognoni, G.5
Fox, K.K.6
-
5
-
-
36148983750
-
TRITON-TIMI 38 Investigators. Prasugrel versus clopidogrel in patients with acute coronary syndromes
-
Wiviott SD, Braunwald E, McCabe CH, et al; TRITON-TIMI 38 Investigators. Prasugrel versus clopidogrel in patients with acute coronary syndromes. N Engl J Med. 2007;357:2001–2015
-
(2007)
N Engl J Med
, vol.357
, pp. 2001-2015
-
-
Wiviott, S.D.1
Braunwald, E.2
McCabe, C.H.3
-
6
-
-
0035512676
-
Association between aspirin and upper gastrointestinal complications: Systematic review of epidemiologic studies
-
Garcia-Rodriguez LA, Hernandez-Diaz S, de Abajo FJ. Association between aspirin and upper gastrointestinal complications: systematic review of epidemiologic studies. Br J Clin Pharmacol. 2001;52:563–571
-
(2001)
Br J Clin Pharmacol
, vol.52
, pp. 563-571
-
-
Garcia-Rodriguez, L.A.1
Hernandez-Diaz, S.2
De Abajo, F.J.3
-
7
-
-
0141919739
-
Clopidogrel in Unstable Angina to Prevent Recurrent Events (CURE) Trial Investigators. Effects of aspirin dose when used alone or in combination with clopidogrel in patients with acute coronary syndromes: Observations from the clopidogrel in unstable angina to prevent recurrent events (CURE) study
-
Peters RJ, Mehta SR, Fox KA, et al; Clopidogrel in Unstable Angina to Prevent Recurrent Events (CURE) Trial Investigators. Effects of aspirin dose when used alone or in combination with clopidogrel in patients with acute coronary syndromes: observations from the clopidogrel in unstable angina to prevent recurrent events (CURE) study. Circulation. 2003;108:1682–1687
-
(2003)
Circulation
, vol.108
, pp. 1682-1687
-
-
Peters, R.J.1
Mehta, S.R.2
Fox, K.A.3
-
8
-
-
24944511514
-
Tungstate decreases weight gain and adiposity in obese rats through increased thermogenesis and lipid oxidation
-
Claret M, Corominola H, Canals I, et al. Tungstate decreases weight gain and adiposity in obese rats through increased thermogenesis and lipid oxidation. Endocrinology. 2005;146:4362–4369
-
(2005)
Endocrinology
, vol.146
, pp. 4362-4369
-
-
Claret, M.1
Corominola, H.2
Canals, I.3
-
9
-
-
39749182718
-
Integration of DIGE and bioinformatics analyses reveals a role of the antiobesity agent tungstate in redox and energy homeostasis pathways in brown adipose tissue
-
Barceló-Batllori S, Kalko SG, Esteban Y, Moreno S, Carmona MC, Gomis R. Integration of DIGE and bioinformatics analyses reveals a role of the antiobesity agent tungstate in redox and energy homeostasis pathways in brown adipose tissue. Mol Cell Proteomics. 2008;7: 378–393
-
(2008)
Mol Cell Proteomics
, vol.7
, pp. 378-393
-
-
Barceló-Batllori, S.1
Kalko, S.G.2
Esteban, Y.3
Moreno, S.4
Carmona, M.C.5
Gomis, R.6
-
10
-
-
77957269135
-
Proof-of-concept trial on the efficacy of sodium tungstate in human obesity
-
Hanzu F, Gomis R, Coves MJ, et al. Proof-of-concept trial on the efficacy of sodium tungstate in human obesity. Diabetes Obes Metab. 2010;12:1013–1018
-
(2010)
Diabetes Obes Metab
, vol.12
, pp. 1013-1018
-
-
Hanzu, F.1
Gomis, R.2
Coves, M.J.3
-
11
-
-
0028128179
-
Insulin-like actions of tungstate in diabetic rats. Normalization of hepatic glucose metabolism
-
Barbera A, Rodriguez-Gil JE, Guinovart JJ. Insulin-like actions of tungstate in diabetic rats. Normalization of hepatic glucose metabolism. J Biol Chem. 1994;269:20047–20053
-
(1994)
J Biol Chem
, vol.269
, pp. 20047-20053
-
-
Barbera, A.1
Rodriguez-Gil, J.E.2
Guinovart, J.J.3
-
12
-
-
0031022433
-
Mechanism of inhibition of protein tyrosine phosphatases by vanadate and pervanadate
-
Huyer G, Liu S, Kelly J, et al. Mechanism of inhibition of protein tyrosine phosphatases by vanadate and pervanadate. Biol Chem. 1997; 272:843–851
-
(1997)
Biol Chem
, vol.272
, pp. 843-851
-
-
Huyer, G.1
Liu, S.2
Kelly, J.3
-
13
-
-
34548258220
-
Double knockouts reveal that protein tyrosine phosphatase 1B is a physiological target of calpain-1 in platelets
-
Kuchay SM, Kim N, Grunz EA, Fay WP, Chishti AH. Double knockouts reveal that protein tyrosine phosphatase 1B is a physiological target of calpain-1 in platelets. Mol Cell Biol. 2007;27:6038–6052
-
(2007)
Mol Cell Biol
, vol.27
, pp. 6038-6052
-
-
Kuchay, S.M.1
Kim, N.2
Grunz, E.A.3
Fay, W.P.4
Chishti, A.H.5
-
14
-
-
24144482771
-
PTP1B is an essential positive regulator of platelet integrin signalling
-
Arias-Salgado EG, Haj F, Dubois C, et al. PTP1B is an essential positive regulator of platelet integrin signalling. J Cell Biol. 2005;170:837–845
-
(2005)
J Cell Biol
, vol.170
, pp. 837-845
-
-
Arias-Salgado, E.G.1
Haj, F.2
Dubois, C.3
-
15
-
-
0033942614
-
Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice
-
Klaman LD, Boss O, Peroni OD, et al. Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice. Mol Cell Biol. 2000;20:5479–5489
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5479-5489
-
-
Klaman, L.D.1
Boss, O.2
Peroni, O.D.3
-
16
-
-
77950366124
-
Inhibition of PTP1B restores IRS1-mediated hepatic insulin signaling in IRS2-deficient mice
-
Gonzalez-Rodriguez A, Mas Gutierrez JA, Sanz-Gonzalez S, Ros M, Burks DJ, Valverde AM. Inhibition of PTP1B restores IRS1-mediated hepatic insulin signaling in IRS2-deficient mice. Diabetes. 2010;59:588–599
-
(2010)
Diabetes
, vol.59
, pp. 588-599
-
-
Gonzalez-Rodriguez, A.1
Mas Gutierrez, J.A.2
Sanz-Gonzalez, S.3
Ros, M.4
Burks, D.J.5
Valverde, A.M.6
-
17
-
-
0029011142
-
Description of an in vitro platelet function analyzer-PFA-100
-
Kundu SK, Heilmann EJ, Sio R, Garcia C, Davidson RM, Ostgaard RA. Description of an in vitro platelet function analyzer-PFA-100. Semin Thromb Hemost. 1995;21:106–112
-
(1995)
Semin Thromb Hemost
, vol.21
, pp. 106-112
-
-
Kundu, S.K.1
Heilmann, E.J.2
Sio, R.3
Garcia, C.4
Davidson, R.M.5
Ostgaard, R.A.6
-
18
-
-
0034663206
-
Testing of platelet deposition on polystyrene surface under flow conditions by the cone and platelet analyzer: Role of platelet activation, fibrinogen and von Willebrand factor
-
Shenkman B, Savion N, Dardik R, Tamarin I, Varon D. Testing of platelet deposition on polystyrene surface under flow conditions by the cone and platelet analyzer: role of platelet activation, fibrinogen and von Willebrand factor. Thromb Res. 2000;99:353–361
-
(2000)
Thromb Res
, vol.99
, pp. 353-361
-
-
Shenkman, B.1
Savion, N.2
Dardik, R.3
Tamarin, I.4
Varon, D.5
-
20
-
-
70449395449
-
Serotonergic mechanisms enhance platelet-mediated thrombogenicity
-
Galan AM, Lopez-Vilchez I, Diaz-Ricart M, et al. Serotonergic mechanisms enhance platelet-mediated thrombogenicity. Thromb Haemost. 2009;102:511–519
-
(2009)
Thromb Haemost
, vol.102
, pp. 511-519
-
-
Galan, A.M.1
Lopez-Vilchez, I.2
Diaz-Ricart, M.3
-
21
-
-
0022586984
-
Development of a computer program to analyze the parameters of platelet-vessel wall interaction
-
Escolar G, Bastida E, Castillo R, Ordinas A. Development of a computer program to analyze the parameters of platelet-vessel wall interaction. Haemostasis. 1986;16:8–14
-
(1986)
Haemostasis
, vol.16
, pp. 8-14
-
-
Escolar, G.1
Bastida, E.2
Castillo, R.3
Ordinas, A.4
-
22
-
-
0346367328
-
Aggregation of blood platelets by adenosine-diphosphate and its reversal
-
Born GVR. Aggregation of blood platelets by adenosine-diphosphate and its reversal. Nature. 1962;194:927–929
-
(1962)
Nature
, vol.194
, pp. 927-929
-
-
Born, G.1
-
23
-
-
33644928315
-
An audit of red cell and blood product use after the institution of thromboelastometry in a cardiac intensive care unit
-
Anderson L, Quasim I, Soutar R, Steven M, Macfie A, Korte W. An audit of red cell and blood product use after the institution of thromboelastometry in a cardiac intensive care unit. Transfus Med. 2006;16: 31–39
-
(2006)
Transfus Med
, vol.16
, pp. 31-39
-
-
Anderson, L.1
Quasim, I.2
Soutar, R.3
Steven, M.4
Macfie, A.5
Korte, W.6
-
24
-
-
0022646192
-
Platelet adhesion and thrombus formation on subendothelium in platelets deficient in glycoproteins IIb-IIIa, Ib, and storage granules
-
Weiss HJ, Turitto VT, Baumgartner HR. Platelet adhesion and thrombus formation on subendothelium in platelets deficient in glycoproteins IIb-IIIa, Ib, and storage granules. Blood. 1986;67:322–330
-
(1986)
Blood
, vol.67
, pp. 322-330
-
-
Weiss, H.J.1
Turitto, V.T.2
Baumgartner, H.R.3
-
25
-
-
0031051447
-
Enhanced increases in cytosolic Ca2+ in ADP-stimulated platelets from patients with delta-storage pool deficiency: A possible indicator of interactions between granule-bound ADP and the membrane ADP receptor
-
Lages B, Weiss HJ. Enhanced increases in cytosolic Ca2+ in ADP-stimulated platelets from patients with delta-storage pool deficiency: a possible indicator of interactions between granule-bound ADP and the membrane ADP receptor. Thromb Haemost. 1997;77:376–382
-
(1997)
Thromb Haemost
, vol.77
, pp. 376-382
-
-
Lages, B.1
Weiss, H.J.2
-
26
-
-
0022401962
-
Adenosine diphosphate as a mediator of platelet aggregation in vivo: An editorial view
-
Born GV. Adenosine diphosphate as a mediator of platelet aggregation in vivo: an editorial view. Circulation. 1985;72:741–746
-
(1985)
Circulation
, vol.72
, pp. 741-746
-
-
Born, G.V.1
-
27
-
-
0025353068
-
Dose and shear rate-dependent effects of heparin on thrombogenesis induced by rabbit aorta subendothelium exposed to flowing human blood
-
Inauen W, Baumgartner HR, Bombeli T, Haeberli A, Straub PW. Dose and shear rate-dependent effects of heparin on thrombogenesis induced by rabbit aorta subendothelium exposed to flowing human blood. Arteriosclerosis. 1990;10:607–615
-
(1990)
Arteriosclerosis
, vol.10
, pp. 607-615
-
-
Inauen, W.1
Baumgartner, H.R.2
Bombeli, T.3
Haeberli, A.4
Straub, P.W.5
-
28
-
-
0028077004
-
Tissue factor-induced coagulation triggers platelet thrombus formation as efficiently as fibrillar collagen at arterial blood flow conditions
-
Orvim U, Roald HE, Stephens RW, Roos N, Sakariassen KS. Tissue factor-induced coagulation triggers platelet thrombus formation as efficiently as fibrillar collagen at arterial blood flow conditions. Arterioscler Thromb. 1994;14:1976–1983
-
(1994)
Arterioscler Thromb
, vol.14
, pp. 1976-1983
-
-
Orvim, U.1
Roald, H.E.2
Stephens, R.W.3
Roos, N.4
Sakariassen, K.S.5
-
29
-
-
0028092832
-
Alpha-thrombin bound to extracellular endothelial matrix induces pronounced fibrin deposition and platelet thrombus growth in flowing non-anticoagulated human blood
-
Salatti JA, Fenton J, Anton P, Sakariassen KS. Alpha-thrombin bound to extracellular endothelial matrix induces pronounced fibrin deposition and platelet thrombus growth in flowing non-anticoagulated human blood. Blood Coagul Fibrinolysis. 1994;5:561–566
-
(1994)
Blood Coagul Fibrinolysis
, vol.5
, pp. 561-566
-
-
Salatti, J.A.1
Fenton, J.2
Anton, P.3
Sakariassen, K.S.4
-
30
-
-
0014289547
-
Fine structural alterations induced in platelets by adenosine diphosphate
-
White JG. Fine structural alterations induced in platelets by adenosine diphosphate. Blood. 1968;31:604–622
-
(1968)
Blood
, vol.31
, pp. 604-622
-
-
White, J.G.1
-
31
-
-
70450199115
-
Focused updates: ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction and ACC/AHA/SCAI guidelines on percutaneous coronary intervention: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
-
Kushner FG, Hand M, Smith SC Jr, et al. Focused updates: ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction and ACC/AHA/SCAI guidelines on percutaneous coronary intervention: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2009;54:2205–2241
-
(2009)
J am Coll Cardiol
, vol.54
, pp. 2205-2241
-
-
Kushner, F.G.1
Hand, M.2
Smith, S.C.3
-
32
-
-
38049183243
-
Focused update of the ACC/AHA 2004 guidelines for the management of patients with ST-elevation myocardial infarction: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines
-
Antman EM, Hand M, Armstrong PW, et al. Focused update of the ACC/AHA 2004 guidelines for the management of patients with ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2007;117:296–329
-
(2007)
Circulation
, vol.117
, pp. 296-329
-
-
Antman, E.M.1
Hand, M.2
Armstrong, P.W.3
-
33
-
-
38049169354
-
Focused update of the ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines
-
King SB 3rd, Smith SC Jr, Hirshfeld JW Jr, et al. Focused update of the ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2007;117:261–295
-
(2007)
Circulation
, vol.117
, pp. 261-295
-
-
King, S.B.1
Smith, S.C.2
Hirshfeld, J.W.3
-
34
-
-
33646732608
-
Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin treated patients with stable coronary artery disease
-
Jernberg T, Payne CD, Winters KJ, et al. Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin treated patients with stable coronary artery disease. Eur Heart J. 2006;27:1166–1173
-
(2006)
Eur Heart J
, vol.27
, pp. 1166-1173
-
-
Jernberg, T.1
Payne, C.D.2
Winters, K.J.3
-
35
-
-
58749094444
-
Cytochrome p-450 polymorphisms and response to clopidogrel
-
Mega JL, Close SL, Wiviott SD, et al. Cytochrome p-450 polymorphisms and response to clopidogrel. N Engl J Med. 2009;360:354–362
-
(2009)
N Engl J Med
, vol.360
, pp. 354-362
-
-
Mega, J.L.1
Close, S.L.2
Wiviott, S.D.3
-
36
-
-
77953911457
-
Working Group on High on-Treatment Platelet Reactivity. Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate
-
Bonello L, Tantry US, Marcucci R, et al; Working Group on High on-Treatment Platelet Reactivity. Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate. J Am Coll Cardiol. 2010;56:919–933
-
(2010)
J am Coll Cardiol
, vol.56
, pp. 919-933
-
-
Bonello, L.1
Tantry, U.S.2
Marcucci, R.3
-
37
-
-
0029583122
-
Crystal structure of the catalytic subunit of human protein phosphatase 1 and its complex with tungstate
-
Egloff MP, Cohen PT, Reinemer P, Barford D. Crystal structure of the catalytic subunit of human protein phosphatase 1 and its complex with tungstate. J Mol Biol. 1995;254:942–959
-
(1995)
J Mol Biol
, vol.254
, pp. 942-959
-
-
Egloff, M.P.1
Cohen, P.T.2
Reinemer, P.3
Barford, D.4
-
39
-
-
0036693750
-
Vanadium and tungsten derivatives as antidiabeticagents: A review of their toxic effects
-
Domingo JL. Vanadium and tungsten derivatives as antidiabeticagents: a review of their toxic effects. Biol Trace Elem Res. 2002;88:97–112
-
(2002)
Biol Trace Elem Res
, vol.88
, pp. 97-112
-
-
Domingo, J.L.1
-
40
-
-
0035061253
-
Tungstate is an effective antidiabetic agent in streptozotocin-induced diabetic rats: A long-term study
-
Barberà A, Gomis RR, Prats N, et al. Tungstate is an effective antidiabetic agent in streptozotocin-induced diabetic rats: a long-term study. Diabetologia. 2001;44:507–513
-
(2001)
Diabetologia
, vol.44
, pp. 507-513
-
-
Barberà, A.1
Gomis, R.R.2
Prats, N.3
-
41
-
-
0031019298
-
Effects of tungstate in neonatally streptozotocin-induced diabetic rats: Mechanism leading to normalization of glycaemia
-
Barbera A, Fernandez-Alvarez J, Truc A, Gomis R, Guinovart JJ. Effects of tungstate in neonatally streptozotocin-induced diabetic rats: mechanism leading to normalization of glycaemia. Diabetologia. 1997;40:143–149
-
(1997)
Diabetologia
, vol.40
, pp. 143-149
-
-
Barbera, A.1
Fernandez-Alvarez, J.2
Truc, A.3
Gomis, R.4
Guinovart, J.J.5
-
42
-
-
0038743115
-
Modulation of glucose transporters in rat diaphragm by sodium tungstate
-
Giron MD, Caballero JJ, Vargas AM, Suarez MD, Guinovart JJ, Salto R. Modulation of glucose transporters in rat diaphragm by sodium tungstate. FEBS Lett. 2003;542:84–88
-
(2003)
FEBS Lett
, vol.542
, pp. 84-88
-
-
Giron, M.D.1
Caballero, J.J.2
Vargas, A.M.3
Suarez, M.D.4
Guinovart, J.J.5
Salto, R.6
-
43
-
-
0343090412
-
Effects of sodium tungstate on insulin and glucagon secretion in the perfused rat pancreas
-
Rodriguez-Gallardo J, Silvestre RA, Egido EM, Marco J. Effects of sodium tungstate on insulin and glucagon secretion in the perfused rat pancreas. Eur J Pharmacol. 2000;402:199–204
-
(2000)
Eur J Pharmacol
, vol.402
, pp. 199-204
-
-
Rodriguez-Gallardo, J.1
Silvestre, R.A.2
Egido, E.M.3
Marco, J.4
-
44
-
-
84872919211
-
Sodium tungstate activates glycogen synthesis through a non-canonical mechanism involving G-proteins
-
Zafra D, Nocito L, Domínguez J, Guinovart JJ. Sodium tungstate activates glycogen synthesis through a non-canonical mechanism involving G-proteins. FEBS Lett. 2013;587:291–296
-
(2013)
FEBS Lett
, vol.587
, pp. 291-296
-
-
Zafra, D.1
Nocito, L.2
Domínguez, J.3
Guinovart, J.J.4
-
45
-
-
79251575575
-
Von Willebrand factor-mediated platelet adhesion is critical for deep vein thrombosis in mouse models
-
Brill A, Fuchs TA, Chauhan AK, et al. von Willebrand factor-mediated platelet adhesion is critical for deep vein thrombosis in mouse models. Blood. 2011;117:1400–1407
-
(2011)
Blood
, vol.117
, pp. 1400-1407
-
-
Brill, A.1
Fuchs, T.A.2
Chauhan, A.K.3
-
46
-
-
84861750668
-
Monocytes, neutrophils and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo
-
von Brühl ML, Stark K, Steinhart A, et al. Monocytes, neutrophils and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo. J Exp Med. 2012;209:819–835.
-
(2012)
J Exp Med
, vol.209
, pp. 819-835
-
-
Von Brühl, M.L.1
Stark, K.2
Steinhart, A.3
|