Fatty acid-binding proteins 1 and 2 differentially modulate the activation of peroxisome proliferator-activated receptor α in a ligand-selective manner

Journal of Biological Chemistry

Volumn 290, Issue 22, 2015, Pages 13895-13906

  Hughes, Maria L R ^a   Liu, Bonan ^a   Halls, Michelle L ^a,c   Wagstaff, Kylie M ^a,c   Patil, Rahul ^a   Velkov, Tony ^a   Jans, David A ^a   Bunnett, Nigel W ^a,b   Scanlon, Martin J ^a   Porter, Christopher J H ^a  

^a MONASH UNIVERSITY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c NATIONAL HEALTH AND MEDICAL RESEARCH COUNCIL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROLIFERATION; CHEMICAL ACTIVATION; CYTOLOGY; FATTY ACIDS; FLUORESCENCE IMAGING; LIGANDS; METABOLISM; PROTEINS; TISSUE;

FATTY ACID-BINDING PROTEINS; LIPID-BINDING PROTEINS; NUCLEAR ACCUMULATION; NUCLEAR HORMONE RECEPTOR; NUCLEAR LOCALIZATION; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; PHYSIOLOGICAL PROCESS; THERAPEUTIC TARGETS;

BIOACTIVITY;

2 [4 [2 [3 CYCLOHEXYL 1 (4 CYCLOHEXYLBUTYL)UREIDO]ETHYL]PHENYLTHIO] 2 METHYLPROPIONIC ACID; FATTY ACID BINDING PROTEIN; FATTY ACID BINDING PROTEIN 1; FATTY ACID BINDING PROTEIN 2; FENOFIBRATE; KARYOPHERIN ALPHA; KARYOPHERIN BETA; LUCIFERASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; UNCLASSIFIED DRUG; FABP1 PROTEIN, HUMAN; FABP2 PROTEIN, HUMAN; KARYOPHERIN; LIGAND; LIPID; PROTEIN BINDING;

ARTICLE; BINDING AFFINITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG PROTEIN BINDING; ENZYME ACTIVITY; IN VITRO STUDY; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; TRANSCRIPTION INITIATION; ANIMAL; CALORIMETRY; CELL NUCLEUS; CHEMISTRY; CHLOROCEBUS AETHIOPS; COS 1 CELL LINE; DRUG DELIVERY SYSTEM; DRUG DESIGN; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE EXPRESSION REGULATION; HUMAN; METABOLISM; PLASMID; PROTEIN ANALYSIS; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BIOLOGICAL TRANSPORT; CALORIMETRY; CELL NUCLEUS; CERCOPITHECUS AETHIOPS; COS CELLS; DRUG DELIVERY SYSTEMS; DRUG DESIGN; FATTY ACID-BINDING PROTEINS; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE EXPRESSION REGULATION; HUMANS; KARYOPHERINS; LIGANDS; LIPIDS; PLASMIDS; PPAR ALPHA; PROTEIN BINDING; PROTEIN INTERACTION MAPPING;

EID: 84930623331     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.605998     Document Type: Article

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