Surface-engineered dendrimeric nanoconjugates for macrophage-targeted delivery of amphotericin B: Formulation development and in vitro and in vivo evaluation

Antimicrobial Agents and Chemotherapy

Volumn 59, Issue 5, 2015, Pages 2479-2487

  Jain, Keerti ^a,b   Verma, Ashwni Kumar ^c   Mishra, Prabhat Ranjan ^c   Jain, Narendra Kumar ^a,b  

^a DR H S GOUR UNIVERSITY   (India)

^b ISF COLLEGE OF PHARMACY   (India)

^c CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B; DENDRIMER; MANNOSE; NANOCONJUGATE; POLY(PROPYLENE IMINE); UNCLASSIFIED DRUG; ANTIPROTOZOAL AGENT; POLY(PROPYLENEIMINE); POLYPROPYLENE;

AMASTIGOTE; ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIPROTOZOAL ACTIVITY; AREA UNDER THE CURVE; ARTICLE; ATOMIC FORCE MICROSCOPY; BLOOD TOXICITY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG HALF LIFE; DRUG RELEASE; DRUG STABILITY; ERYTHROCYTE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROSCOPY; LEISHMANIA DONOVANI; MACROPHAGE; MAXIMUM PLASMA CONCENTRATION; MOUSE; NEPHROTOXICITY; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; VISCERAL LEISHMANIASIS; ANIMAL; BAGG ALBINO MOUSE; CELL LINE; CHEMISTRY; DRUG EFFECTS; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STANDARDS;

AMPHOTERICIN B; ANIMALS; ANTIPROTOZOAL AGENTS; CELL LINE; DRUG DELIVERY SYSTEMS; HUMANS; LEISHMANIA DONOVANI; MACROPHAGES; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, INBRED BALB C; NANOCONJUGATES; POLYPROPYLENES;

EID: 84930572489     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.04213-14     Document Type: Article

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