High-yield production of a human monoclonal IgG by rhizosecretion in hydroponic tobacco cultures

Plant Biotechnology Journal

Volumn 14, Issue 2, 2016, Pages 615-624

  Madeira, Luisa M ^a,f   Szeto, Tim H ^a   Henquet, Maurice ^b   Raven, Nicole ^c   Runions, John ^d   Huddleston, Jon ^e   Garrard, Ian ^e   Drake, Pascal M W ^a   Ma, Julian K C ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b WAGENINGEN UNIVERSITY   (Netherlands)

^c FRAUNHOFER INSTITUTE FOR MOLECULAR BIOLOGY AND APPLIED ECOLOGY IME   (Germany)

^d OXFORD BROOKES UNIVERSITY   (United Kingdom)

^e BRUNEL UNIVERSITY   (United Kingdom)

^f UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Genetically modified plants; Monoclonal antibody; Recombinant antibody production; Rhizosecretion

Indexed keywords

IMMUNOGLOBULIN G; INDOLEACETIC ACID DERIVATIVE; MONOCLONAL ANTIBODY; NITRIC ACID DERIVATIVE; VITRONECTIN;

ANIMAL; BIOSYNTHESIS; CELL CULTURE TECHNIQUE; CHO CELL LINE; CRICETULUS; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; GLYCOSYLATION; HAMSTER; HUMAN; HYDROPONICS; METABOLISM; PHENOTYPE; PLANT ROOT; PROCEDURES; TOBACCO; TRANSGENIC PLANT;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL CULTURE TECHNIQUES; CHO CELLS; CRICETINAE; CRICETULUS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLYCOSYLATION; HUMANS; HYDROPONICS; IMMUNOGLOBULIN G; INDOLEACETIC ACIDS; NITRATES; PHENOTYPE; PLANT ROOTS; PLANTS, GENETICALLY MODIFIED; TOBACCO; VITRONECTIN;

EID: 84930526061     PISSN: 14677644     EISSN: 14677652     Source Type: Journal    
DOI: 10.1111/pbi.12407     Document Type: Article

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