-
2
-
-
14844353574
-
Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors
-
PEART MJ, SMYTH GK, VAN LAARR K, BOWTELL DD, RICHON VM et al. Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors. PNAS 2005; 102: 3697–3702. http://dx.doi.org/10.1073/pnas.0500369102
-
(2005)
PNAS
, vol.102
, pp. 3697-3702
-
-
Peart, M.J.1
Smyth, G.K.2
Van Laarr, K.3
Bowtell, D.D.4
Richon, V.M.5
-
3
-
-
0042905956
-
Gene expression profiling of multiple histone deacetylase (HDAC) inhbitors: Defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines
-
Glaser KB, Staver MJ, Waring JF, Stender J, Ulrich RG et al. Gene expression profiling of multiple histone deacetylase (HDAC) inhbitors: defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines. Mol Cancer Ther 2003; 2:151–163.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 151-163
-
-
Glaser, K.B.1
Staver, M.J.2
Waring, J.F.3
Stender, J.4
Ulrich, R.G.5
-
4
-
-
79952396960
-
Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes
-
Bantscheff M, Hopf C, Savitski MM, Dittmann A, Grandi P et al. Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes. Nat Biotechnol 2011; 29: 255–265. http://dx.doi.org/10.1038/nbt.1759
-
(2011)
Nat Biotechnol
, vol.29
, pp. 255-265
-
-
Bantscheff, M.1
Hopf, C.2
Savitski, M.M.3
Dittmann, A.4
Grandi, P.5
-
5
-
-
10344262564
-
Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes
-
SHIMIZE S, KANASEKE T, MIZUSHIMA N, MIZUTA T, Arakawa-Kobayashi S et al. Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes. Nat Cell Biol 2004; 6: 1221–1228. http://dx.doi.org/10.1038/ncb1192
-
(2004)
Nat Cell Biol
, vol.6
, pp. 1221-1228
-
-
Shimize, S.1
Kanaseke, T.2
Mizushima, N.3
Mizuta, T.4
Arakawa-Kobayashi, S.5
-
6
-
-
1542513774
-
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is required for induction of autophagy during lumen formation in vitro
-
MILLS KR, REGINATO M, DEBNATH J, QUEENAN B, BRUGGEJ S. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is required for induction of autophagy during lumen formation in vitro. PNAS 2004; 101: 3438–3443. http://dx.doi.org/10.1073/pnas.0400443101
-
(2004)
PNAS
, vol.101
, pp. 3438-3443
-
-
Mills, K.R.1
Reginato, M.2
Debnath, J.3
Queenan, B.4
Bruggej, S.5
-
7
-
-
80051668850
-
The dual role of autophagy in cancer
-
ESKELINEN EL. The dual role of autophagy in cancer. Curr Opin Pharmacol 2011; 11: 294–300. http://dx.doi.org/10.1016/j.coph.2011.03.009
-
(2011)
Curr Opin Pharmacol
, vol.11
, pp. 294-300
-
-
Eskelinen, E.L.1
-
8
-
-
80052306066
-
Autophagy protects breast cancer cells from epirubicin-induced apoptosis and facilitates epirubicin-resistance development
-
SUN W, CHEN J, WANG Y, ZHENG H. Autophagy protects breast cancer cells from epirubicin-induced apoptosis and facilitates epirubicin-resistance development. Autophagy 2011; 7: 1035–1044. http://dx.doi.org/10.4161/auto.7.9.16521
-
(2011)
Autophagy
, vol.7
, pp. 1035-1044
-
-
Sun, W.1
Chen, J.2
Wang, Y.3
Zheng, H.4
-
9
-
-
78649464206
-
Autophagy is therapeutic target in anticancer drug resistance
-
CHEN S, KEHMAN SK, ZHANG W, WEN A, YAO L et al. Autophagy is therapeutic target in anticancer drug resistance. BBA-Rev Cancer 2010; 1806: 220–229.
-
(2010)
Bba-Rev Cancer
, vol.1806
, pp. 220-229
-
-
Chen, S.1
Kehman, S.K.2
Zhang, W.3
Wen, A.4
Yao, L.5
-
10
-
-
84055190790
-
Histone deacetylase inhibitors (HDACIs). Structure-activity relationships: History and new QSARperspectives
-
PONTIKI E, Hadjipavlou-Litina D. Histone deacetylase inhibitors (HDACIs). Structure-activity relationships: history and new QSARperspectives. Med Res Rev 2012; 32: 1–165. http://dx.doi.org/10.1002/med.20200
-
(2012)
Med Res Rev
, vol.32
, pp. 1-165
-
-
Pontiki, E.1
Hadjipavlou-Litina, D.2
-
11
-
-
84896727846
-
Discovery of potent HDAC inhibitors based on Chlamydocin with inhibitory effects on cell migration
-
WANG S, LI X, WEI Y, XIU Z, NISHINO N. Discovery of potent HDAC inhibitors based on Chlamydocin with inhibitory effects on cell migration. ChemMedChem 2014; 9: 627–637. http://dx.doi.org/10.1002/cmdc.201300372
-
(2014)
Chemmedchem
, vol.9
, pp. 627-637
-
-
Wang, S.1
Li, X.2
Wei, Y.3
Xiu, Z.4
Nishino, N.5
-
13
-
-
33847255913
-
CONTEP. Primary systemic therapy for operable breast cancer: A review of clinical trials and perspectives
-
GUARNERI V, FRASSOLDATI A, GIOVANNELLI S, BORGHI F, CONTEP. Primary systemic therapy for operable breast cancer: a review of clinical trials and perspectives. Cancer Lett 2007; 248: 175–185. http://dx.doi.org/10.1016/j.canlet.2006.07.001
-
(2007)
Cancer Lett
, vol.248
, pp. 175-185
-
-
Guarneri, V.1
Frassoldati, A.2
Giovannelli, S.3
Borghi, F.4
-
14
-
-
27144475816
-
Histone deacetylases in acute myeloid leukemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors
-
BRADBURY CA, KHANIM FL, HAYDEN R, BUNCEC M, WHITED A et al. Histone deacetylases in acute myeloid leukemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors. Leukemia, 2005; 9: 1751–1759. http://dx.doi.org/10.1038/sj.leu.2403910
-
(2005)
Leukemia
, vol.9
, pp. 1751-1759
-
-
Bradbury, C.A.1
Khanim, F.L.2
Hayden, R.3
Buncec, M.4
Whited, A.5
-
15
-
-
33746298246
-
Mechanisms of cytochrome c release from mitochondria
-
GARRIDO C, GALLUZZI L, BRUNET M, PUIG PE, DIDELOT C et al. Mechanisms of cytochrome c release from mitochondria. Cell Death Differ 2006; 13: 1423–1433. http://dx.doi.org/10.1038/sj.cdd.4401950
-
(2006)
Cell Death Differ
, vol.13
, pp. 1423-1433
-
-
Garrido, C.1
Galluzzi, L.2
Brunet, M.3
Puig, P.E.4
Didelot, C.5
-
16
-
-
33947714475
-
Caspase inhibitors promote alternative cell death pathways
-
VANDENABEELE P, BERGHE TV, FESTJENS N. Caspase inhibitors promote alternative cell death pathways. Sci. STKE 2006; 358: pe44.
-
(2006)
Sci. STKE
, vol.358
-
-
Vandenabeele, P.1
Berghe, T.V.2
Festjens, N.3
-
18
-
-
79957628179
-
Autophagy inhibition promotes paclitaxel-induced apoptosis in cancer cells
-
XI G, HU X, WU B, JIANG H, YOUNG CTF, PANG Y et al. Autophagy inhibition promotes paclitaxel-induced apoptosis in cancer cells. Cancer lett 2011; 307: 141–148. http://dx.doi.org/10.1016/j.canlet.2011.03.026
-
(2011)
Cancer Lett
, vol.307
, pp. 141-148
-
-
Xi, G.1
Hu, X.2
Wu, B.3
Jiang, H.4
Young, C.5
Pang, Y.6
-
19
-
-
84898857835
-
Inhibition of autophagy induced by TSA sensitizes colon cell to radiation
-
HEG, WANG Y, PANG X, ZHANG B. Inhibition of autophagy induced by TSA sensitizes colon cell to radiation. Tumor Biol 2014; 35: 1003–1011. http://dx.doi.org/10.1007/s13277-013-1134-z
-
(2014)
Tumor Biol
, vol.35
, pp. 1003-1011
-
-
Heg, W.1
Pang, X.2
Zhang, B.3
-
20
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
KABEYA Y, MIZUSHIMA N, UENO T, YAMAMOTO A, KIRISAKO T et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 2000; 19: 5720–5728. http://dx.doi.org/10.1093/emboj/19.21.5720
-
(2000)
EMBO J
, vol.19
, pp. 5720-5728
-
-
Kabeya, Y.1
Mizushima, N.2
Ueno, T.3
Yamamoto, A.4
Kirisako, T.5
-
21
-
-
36248982150
-
Autophagy induced by suberoylanilide hydroxamic acid in Hela S3 cells involves inhibition of protein kinase B and up-regulation of Beclin 1
-
CAO Q, YU C, XUE R, HSUEH W, PAN P et al. Autophagy induced by suberoylanilide hydroxamic acid in Hela S3 cells involves inhibition of protein kinase B and up-regulation of Beclin 1. Int J Biochem Cell B 2008; 40: 272–283. http://dx.doi.org/10.1016/j.biocel.2007.07.020
-
(2008)
Int J Biochem Cell B
, vol.40
, pp. 272-283
-
-
Cao, Q.1
Yu, C.2
Xue, R.3
Hsueh, W.4
Pan, P.5
-
22
-
-
0345166111
-
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
-
YUE Z, JIN S, YANG C, LEVINEA J, HEINTZ N. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. PNAS 2003; 100: 15077–15082. http://dx.doi.org/10.1073/pnas.2436255100
-
(2003)
PNAS
, vol.100
, pp. 15077-15082
-
-
Yue, Z.1
Jin, S.2
Yang, C.3
Levinea, J.4
Heintz, N.5
-
23
-
-
78649636176
-
Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria
-
VIRAWAN E, WALLE LV, KERSSE K, CORNELIS S, CLAERHOUT S et al. Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria. Cell Death Dis. 2010; doi:10.1038/cddis.2009.16. http://dx.doi.org/10.1038/cddis.2009.16
-
(2010)
Cell Death Dis
-
-
Virawan, E.1
Walle, L.V.2
Kersse, K.3
Cornelis, S.4
Claerhout, S.5
-
24
-
-
57749089665
-
Caspase-mediated cleavage of ATG6/Beclin-1 links apoptosis to autophagy in Hela cells
-
CHO DH, JO YK, HWANG JJ, LEE YM, ROH SA et al. Caspase-mediated cleavage of ATG6/Beclin-1 links apoptosis to autophagy in Hela cells. Cancer Lett 2009; 274: 95–100. http://dx.doi.org/10.1016/j.canlet.2008.09.004
-
(2009)
Cancer Lett
, vol.274
, pp. 95-100
-
-
Cho, D.H.1
Jo, Y.K.2
Hwang, J.J.3
Lee, Y.M.4
Roh, S.A.5
-
25
-
-
33645950778
-
Histone deacetylase inhibitors: Multifunctional anticancer agents
-
LIU T, KULJACA S, TEE A, MARSHALL GM. Histone deacetylase inhibitors: multifunctional anticancer agents. Cancer Treat Rev 2006; 32: 157–165. http://dx.doi.org/10.1016/j.ctrv.2005.12.006
-
(2006)
Cancer Treat Rev
, vol.32
, pp. 157-165
-
-
Liu, T.1
Kuljaca, S.2
Tee, A.3
Marshall, G.M.4
-
26
-
-
77954874814
-
Imiquimod simultaneously induces autophagy and apoptosis in human basal cell carcinoma cells
-
HUANG SW, LIU KT, CHANG CC, CHEN YJ, WU CY et al. Imiquimod simultaneously induces autophagy and apoptosis in human basal cell carcinoma cells. Brit J Dermatol 2010; 163: 310–320. http://dx.doi.org/10.1111/j.1365-2133.2010.09827.x
-
(2010)
Brit J Dermatol
, vol.163
, pp. 310-320
-
-
Huang, S.W.1
Liu, K.T.2
Chang, C.C.3
Chen, Y.J.4
Wu, C.Y.5
-
27
-
-
84876008743
-
Vorinostat-induced autophagy switches from a death-promoting to cytoprotective signal to drive acquired resistance
-
Depere-Richer D, Kinal M, Menasche V, Nielsen TH, Rincon SD et al. Vorinostat-induced autophagy switches from a death-promoting to cytoprotective signal to drive acquired resistance. Cell Death Dis. 2013; doi:10.1038/cddis.2012.210. http://dx.doi.org/10.1038/cddis.2012.210
-
(2013)
Cell Death Dis
-
-
Depere-Richer, D.1
Kinal, M.2
Menasche, V.3
Nielsen, T.H.4
Rincon, S.D.5
-
28
-
-
77957654940
-
Autophagic degradation of active caspase-8
-
HOU W, HAN J, LU C, GOLDSTEIN LA, RABINOWICH H. Autophagic degradation of active caspase-8. Autophagy, 2010; 6: 891–900. http://dx.doi.org/10.4161/auto.6.7.13038
-
(2010)
Autophagy
, vol.6
, pp. 891-900
-
-
Hou, W.1
Han, J.2
Lu, C.3
Goldstein, L.A.4
Rabinowich, H.5
-
29
-
-
33847026354
-
Autophagy delays apoptotic death in breast cancer cells following DNA damage
-
Abedin MJ, McDonnell MA, Lehmann U, Kelekar A. Autophagy delays apoptotic death in breast cancer cells following DNA damage. Cell Death Differ 2007; 14: 500–510. http://dx.doi.org/10.1038/sj.cdd.4402039
-
(2007)
Cell Death Differ
, vol.14
, pp. 500-510
-
-
Abedin, M.J.1
McDonnell, M.A.2
Lehmann, U.3
Kelekar, A.4
-
30
-
-
79953230490
-
Beclin 1 cleavage by caspase-3 inactivates autophagy and promotes apoptosis
-
ZHU Y, ZHAO L, LIU L, GAO P, TIAN W et al. Beclin 1 cleavage by caspase-3 inactivates autophagy and promotes apoptosis. Protein Cell 2010; 1: 468–477. http://dx.doi.org/10.1007/s13238-010-0048-4
-
(2010)
Protein Cell
, vol.1
, pp. 468-477
-
-
Zhu, Y.1
Zhao, L.2
Liu, L.3
Gao, P.4
Tian, W.5
-
31
-
-
36749029400
-
Hitone deacetylase inhibitor suberoylanilide hydroxamic acid induces apoptosis through both mitochondrial and Fas (CD95) signaling in head and neck squamous carcinoma cells
-
GILLENWATER AM, ZHONG M, LOTAN R. Hitone deacetylase inhibitor suberoylanilide hydroxamic acid induces apoptosis through both mitochondrial and Fas (CD95) signaling in head and neck squamous carcinoma cells. Mol Cancer Ther 2007; 6: 2967–2975. http://dx.doi.org/10.1158/1535-7163.MCT-04-0344
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 2967-2975
-
-
Gillenwater, A.M.1
Zhong, M.2
Lotan, R.3
-
32
-
-
49349098483
-
Histone deacetylase inhibitors: Mechanisms of cell death and promise in combination cancer therapy
-
CAREW JS, GILES FJ, NAWROCKI ST. Histone deacetylase inhibitors: mechanisms of cell death and promise in combination cancer therapy. Cancer Lett 2008; 269: 7–17. http://dx.doi.org/10.1016/j.canlet.2008.03.037
-
(2008)
Cancer Lett
, vol.269
, pp. 7-17
-
-
Carew, J.S.1
Giles, F.J.2
Nawrocki, S.T.3
-
33
-
-
78349242181
-
Mechanisms of synergistic antileukemic interactions between valproic acid and cytarabine in pediatric acute myeloid leukemia
-
XIE C, EDWARDS H, XU X, ZHOU H, BUCK SA et al. Mechanisms of synergistic antileukemic interactions between valproic acid and cytarabine in pediatric acute myeloid leukemia. Clin Cancer Res 2010; 16: 5499–5510. http://dx.doi.org/10.1158/1078-0432.CCR-10-1707
-
(2010)
Clin Cancer Res
, vol.16
, pp. 5499-5510
-
-
Xie, C.1
Edwards, H.2
Xu, X.3
Zhou, H.4
Buck, S.A.5
|