Serum concentrations of anthraquinones after intake of Folium Sennae and potential modulation on P-glycoprotein

Planta Medica

Volumn 80, Issue 15, 2014, Pages 1291-1297

  Peng, Yu Hsuan ^a   Lin, Shiuan Pey ^a   Yu, Chung Ping ^a   Tsai, Shang Yuan ^a   Chen, Min Yu ^a   Hou, Yu Chi ^a,b   Chao, Pei Dawn Lee ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

aloe emodin; Cassia angustifolia; Fabaceae; glucuronides; P glycoprotein; rhein

Indexed keywords

ALOE EMODIN; ALOE EMODIN GLUCURONIDE; ALOE EMODIN SULFATE; BETA GLUCURONIDASE; DANTRON; DRUG METABOLITE; GLYCOPROTEIN P INHIBITOR; MULTIDRUG RESISTANCE PROTEIN; RHEIN; RHEIN GLUCURONIDE; RHEIN SULFATE; SENNOSIDE A; SULFATASE; UNCLASSIFIED DRUG; VERAPAMIL; ANTHRAQUINONE DERIVATIVE; GLUCURONIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG HYDROLYSIS; DRUG METABOLISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LIMIT OF QUANTITATION; MALE; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; NONHUMAN; PLANT LEAF; PLASMA CONCENTRATION-TIME CURVE; PROTEIN FUNCTION; PROTEIN INTERACTION; RAT; SENNA; TIME TO MAXIMUM PLASMA CONCENTRATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; CHEMISTRY; DRUG EFFECTS; MEDICINAL PLANT; METABOLISM; ORAL DRUG ADMINISTRATION; SPRAGUE DAWLEY RAT; TUMOR CELL LINE;

ALOE; FABACEAE; SENNA ALEXANDRINA;

ADMINISTRATION, ORAL; ANIMALS; ANTHRAQUINONES; CELL LINE, TUMOR; GLUCURONIDES; HUMANS; MALE; P-GLYCOPROTEINS; PLANT LEAVES; PLANTS, MEDICINAL; RATS, SPRAGUE-DAWLEY; SENNA PLANT;

EID: 84930491315     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0034-1383040     Document Type: Article

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