-
1
-
-
33845338724
-
Projections of global mortality and burden of disease from 2002 to 2030
-
Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med 2006; 3: e442.
-
(2006)
PLoS Med
, vol.3
-
-
Mathers, C.D.1
Loncar, D.2
-
2
-
-
84871099014
-
Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: A systematic analysis for the Global Burden of Disease Study 2010
-
Murray CJ, Vos T, Lozano R, et al. Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012; 380: 2197-2223.
-
(2012)
Lancet
, vol.380
, pp. 2197-2223
-
-
Murray, C.J.1
Vos, T.2
Lozano, R.3
-
3
-
-
84871051576
-
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: A systematic analysis for the Global Burden of Disease Study 2010
-
Vos T, Flaxman AD, Naghavi M, et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012; 380: 2163-2196.
-
(2012)
Lancet
, vol.380
, pp. 2163-2196
-
-
Vos, T.1
Flaxman, A.D.2
Naghavi, M.3
-
4
-
-
69149102202
-
Chronic obstructive pulmonary disease in non-smokers
-
Salvi SS, Barnes PJ. Chronic obstructive pulmonary disease in non-smokers. Lancet 2009; 374: 733-743.
-
(2009)
Lancet
, vol.374
, pp. 733-743
-
-
Salvi, S.S.1
Barnes, P.J.2
-
5
-
-
33751236493
-
Developing COPD: A 25 year follow up study of the general population
-
Lokke A, Lange P, Scharling H, et al. Developing COPD: a 25 year follow up study of the general population. Thorax 2006; 61: 935-939.
-
(2006)
Thorax
, vol.61
, pp. 935-939
-
-
Lokke, A.1
Lange, P.2
Scharling, H.3
-
6
-
-
84862833519
-
Improved patient outcome with smoking cessation: When is it too late?
-
Wu J, Sin DD. Improved patient outcome with smoking cessation: when is it too late? Int J Chron Obstruct Pulmon Dis 2011; 6: 259-267.
-
(2011)
Int J Chron Obstruct Pulmon Dis
, vol.6
, pp. 259-267
-
-
Wu, J.1
Sin, D.D.2
-
7
-
-
58849113557
-
COPD-related morbidity and mortality after smoking cessation: Status of the evidence
-
Godtfredsen NS, Lam TH, Hansel TT, et al. COPD-related morbidity and mortality after smoking cessation: status of the evidence. Eur Respir J 2008; 32: 844-853.
-
(2008)
Eur Respir J
, vol.32
, pp. 844-853
-
-
Godtfredsen, N.S.1
Lam, T.H.2
Hansel, T.T.3
-
8
-
-
80155137352
-
COPD association and repeatability of blood biomarkers in the ECLIPSE cohort
-
Dickens JA, Miller BE, Edwards LD, et al. COPD association and repeatability of blood biomarkers in the ECLIPSE cohort. Respir Res 2011; 12: 146.
-
(2011)
Respir Res
, vol.12
, pp. 146
-
-
Dickens, J.A.1
Miller, B.E.2
Edwards, L.D.3
-
9
-
-
42949146028
-
Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE)
-
Vestbo J, Anderson W, Coxson HO, et al. Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE). Eur Respir J 2008; 31: 869-873.
-
(2008)
Eur Respir J
, vol.31
, pp. 869-873
-
-
Vestbo, J.1
Anderson, W.2
Coxson, H.O.3
-
10
-
-
71049160113
-
Methods for therapeutic trials in COPD: Lessons from the TORCH trial
-
Keene ON, Vestbo J, Anderson JA, et al. Methods for therapeutic trials in COPD: lessons from the TORCH trial. Eur Respir J 2009; 34: 1018-1023.
-
(2009)
Eur Respir J
, vol.34
, pp. 1018-1023
-
-
Keene, O.N.1
Vestbo, J.2
Anderson, J.A.3
-
11
-
-
44949157858
-
Randomized clinical trials and observational studies: Guidelines for assessing respective strengths and limitations
-
Hannan EL. Randomized clinical trials and observational studies: guidelines for assessing respective strengths and limitations. JACC Cardiovasc Interv 2008; 1: 211-217.
-
(2008)
JACC Cardiovasc Interv
, vol.1
, pp. 211-217
-
-
Hannan, E.L.1
-
12
-
-
38849186086
-
Premature discontinuation of patients: A potential bias in COPD clinical trials
-
Kesten S, Plautz M, Piquette CA, et al. Premature discontinuation of patients: a potential bias in COPD clinical trials. Eur Respir J 2007; 30: 898-906.
-
(2007)
Eur Respir J
, vol.30
, pp. 898-906
-
-
Kesten, S.1
Plautz, M.2
Piquette, C.A.3
-
13
-
-
57849129354
-
De testimonio: on the evidence for decisions about the use of therapeutic interventions
-
Rawlins M. De testimonio: on the evidence for decisions about the use of therapeutic interventions. Clin Med 2008; 8: 579-588.
-
(2008)
Clin Med
, vol.8
, pp. 579-588
-
-
Rawlins, M.1
-
14
-
-
84895918167
-
Randomized controlled trials and real life studies. Approaches and methodologies: A clinical point of view
-
Saturni S, Bellini F, Braido F, et al. Randomized controlled trials and real life studies. Approaches and methodologies: a clinical point of view. Pulm Pharmacol Ther 2014; 27: 129-138.
-
(2014)
Pulm Pharmacol Ther
, vol.27
, pp. 129-138
-
-
Saturni, S.1
Bellini, F.2
Braido, F.3
-
15
-
-
34548227410
-
What have we learned from large drug treatment trials in COPD?
-
Calverley PM, Rennard SI. What have we learned from large drug treatment trials in COPD? Lancet 2007; 370: 774-785.
-
(2007)
Lancet
, vol.370
, pp. 774-785
-
-
Calverley, P.M.1
Rennard, S.I.2
-
16
-
-
77956084309
-
Management of stable chronic obstructive pulmonary disease in primary and secondary care: Summary of updated NICE guidance
-
O'Reilly J, Jones MM, Parnham J, et al. Management of stable chronic obstructive pulmonary disease in primary and secondary care: summary of updated NICE guidance. BMJ 2010; 340: c3134.
-
(2010)
BMJ
, vol.340
-
-
O'Reilly, J.1
Jones, M.M.2
Parnham, J.3
-
17
-
-
33847172367
-
Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease
-
Calverley PM, Anderson JA, Celli B, et al. Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease. N Engl J Med 2007; 356: 775-789.
-
(2007)
N Engl J Med
, vol.356
, pp. 775-789
-
-
Calverley, P.M.1
Anderson, J.A.2
Celli, B.3
-
18
-
-
53749102775
-
A 4-year trial of tiotropium in chronic obstructive pulmonary disease
-
Tashkin DP, Celli B, Senn S, et al. A 4-year trial of tiotropium in chronic obstructive pulmonary disease. N Engl J Med 2008; 359: 1543-1554.
-
(2008)
N Engl J Med
, vol.359
, pp. 1543-1554
-
-
Tashkin, D.P.1
Celli, B.2
Senn, S.3
-
19
-
-
84885734407
-
Tiotropium Respimat inhaler and the risk of death in COPD
-
Wise RA, Anzueto A, Cotton D, et al. Tiotropium Respimat inhaler and the risk of death in COPD. N Engl J Med 2013; 369: 1491-1501.
-
(2013)
N Engl J Med
, vol.369
, pp. 1491-1501
-
-
Wise, R.A.1
Anzueto, A.2
Cotton, D.3
-
20
-
-
63349092855
-
Temporal clustering of exacerbations in chronic obstructive pulmonary disease
-
Hurst JR, Donaldson GC, Quint JK, et al. Temporal clustering of exacerbations in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2009; 179: 369-374.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, pp. 369-374
-
-
Hurst, J.R.1
Donaldson, G.C.2
Quint, J.K.3
-
21
-
-
52749099778
-
Statistical analysis of exacerbation rates in COPD: TRISTAN and ISOLDE revisited
-
Keene ON, Calverley PM, Jones PW, et al. Statistical analysis of exacerbation rates in COPD: TRISTAN and ISOLDE revisited. Eur Respir J 2008; 32: 17-24.
-
(2008)
Eur Respir J
, vol.32
, pp. 17-24
-
-
Keene, O.N.1
Calverley, P.M.2
Jones, P.W.3
-
22
-
-
79953166862
-
Tiotropium versus salmeterol for the prevention of exacerbations of COPD
-
Vogelmeier C, Hederer B, Glaab T, et al. Tiotropium versus salmeterol for the prevention of exacerbations of COPD. N Engl J Med 2011; 364: 1093-1103.
-
(2011)
N Engl J Med
, vol.364
, pp. 1093-1103
-
-
Vogelmeier, C.1
Hederer, B.2
Glaab, T.3
-
23
-
-
78650093203
-
Development of the EXAcerbations of Chronic Obstructive Pulmonary Disease Tool (EXACT): A patient-reported outcome (PRO) measure
-
Leidy NK, Wilcox TK, Jones PW, et al. Development of the EXAcerbations of Chronic Obstructive Pulmonary Disease Tool (EXACT): a patient-reported outcome (PRO) measure. Value Health 2010; 13: 965-975.
-
(2010)
Value Health
, vol.13
, pp. 965-975
-
-
Leidy, N.K.1
Wilcox, T.K.2
Jones, P.W.3
-
24
-
-
0041853629
-
Bronchodilator reversibility testing in chronic obstructive pulmonary disease
-
Calverley PM, Burge PS, Spencer S, et al. Bronchodilator reversibility testing in chronic obstructive pulmonary disease. Thorax 2003; 58: 659-664.
-
(2003)
Thorax
, vol.58
, pp. 659-664
-
-
Calverley, P.M.1
Burge, P.S.2
Spencer, S.3
-
25
-
-
84890316324
-
Annual rates of change in pre- vs. post-bronchodilator FEV1 and FVC over 4 years in moderate to very severe COPD
-
Tashkin DP, Li N, Halpin D, et al. Annual rates of change in pre- vs. post-bronchodilator FEV1 and FVC over 4 years in moderate to very severe COPD. Respir Med 2013; 107: 1904-1911.
-
(2013)
Respir Med
, vol.107
, pp. 1904-1911
-
-
Tashkin, D.P.1
Li, N.2
Halpin, D.3
-
26
-
-
84864015892
-
Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease
-
Albert P, Agusti A, Edwards L, et al. Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease. Thorax 2012; 67: 701-708.
-
(2012)
Thorax
, vol.67
, pp. 701-708
-
-
Albert, P.1
Agusti, A.2
Edwards, L.3
-
27
-
-
84883466304
-
Bronchodilator reversibility in chronic obstructive pulmonary disease: Use and limitations
-
Calverley PM, Albert P, Walker PP. Bronchodilator reversibility in chronic obstructive pulmonary disease: use and limitations. Lancet Respir Med 2013; 1: 564-573.
-
(2013)
Lancet Respir Med
, vol.1
, pp. 564-573
-
-
Calverley, P.M.1
Albert, P.2
Walker, P.P.3
-
28
-
-
0038075468
-
A randomized trial comparing lung-volume-reduction surgery with medical therapy for severe emphysema
-
Fishman A, Martinez F, Naunheim K, et al. A randomized trial comparing lung-volume-reduction surgery with medical therapy for severe emphysema. N Engl J Med 2003; 348: 2059-2073.
-
(2003)
N Engl J Med
, vol.348
, pp. 2059-2073
-
-
Fishman, A.1
Martinez, F.2
Naunheim, K.3
-
29
-
-
79954594717
-
Alternatives to lung transplantation: Lung volume reduction for COPD
-
Criner GJ. Alternatives to lung transplantation: lung volume reduction for COPD. Clin Chest Med 2011; 32: 379-397.
-
(2011)
Clin Chest Med
, vol.32
, pp. 379-397
-
-
Criner, G.J.1
-
30
-
-
84858799802
-
Efficacy predictors of lung volume reduction with Zephyr valves in a European cohort
-
Herth FJ, Noppen M, Valipour A, et al. Efficacy predictors of lung volume reduction with Zephyr valves in a European cohort. Eur Respir J 2012; 39: 1334-1342.
-
(2012)
Eur Respir J
, vol.39
, pp. 1334-1342
-
-
Herth, F.J.1
Noppen, M.2
Valipour, A.3
-
31
-
-
84922292304
-
Lung volume reduction coil treatment for patients with severe emphysema: A European multicentre trial
-
Deslee G, Klooster K, Hetzel M, et al. Lung volume reduction coil treatment for patients with severe emphysema: a European multicentre trial. Thorax 2014; 69: 980-986.
-
(2014)
Thorax
, vol.69
, pp. 980-986
-
-
Deslee, G.1
Klooster, K.2
Hetzel, M.3
-
32
-
-
84899055614
-
Diagnostic performance comparison of the Chartis System and high-resolution computerized tomography fissure analysis for planning endoscopic lung volume reduction
-
Gompelmann D, Eberhardt R, Slebos DJ, et al. Diagnostic performance comparison of the Chartis System and high-resolution computerized tomography fissure analysis for planning endoscopic lung volume reduction. Respirology 2014; 19: 524-530.
-
(2014)
Respirology
, vol.19
, pp. 524-530
-
-
Gompelmann, D.1
Eberhardt, R.2
Slebos, D.J.3
-
33
-
-
77957127502
-
A randomized study of endobronchial valves for advanced emphysema
-
Sciurba FC, Ernst A, Herth FJ, et al. A randomized study of endobronchial valves for advanced emphysema. N Engl J Med 2010; 363: 1233-1244.
-
(2010)
N Engl J Med
, vol.363
, pp. 1233-1244
-
-
Sciurba, F.C.1
Ernst, A.2
Herth, F.J.3
-
34
-
-
70349097551
-
Development and first validation of the COPD Assessment Test
-
Jones PW, Harding G, Berry P, et al. Development and first validation of the COPD Assessment Test. Eur Respir J 2009; 34: 648-654.
-
(2009)
Eur Respir J
, vol.34
, pp. 648-654
-
-
Jones, P.W.1
Harding, G.2
Berry, P.3
-
35
-
-
37849011194
-
The prevention of chronic obstructive pulmonary disease exacerbations by salmeterol/fluticasone propionate or tiotropium bromide
-
Wedzicha JA, Calverley PM, Seemungal TA, et al. The prevention of chronic obstructive pulmonary disease exacerbations by salmeterol/fluticasone propionate or tiotropium bromide. Am J Respir Crit Care Med 2008; 177: 19-26.
-
(2008)
Am J Respir Crit Care Med
, vol.177
, pp. 19-26
-
-
Wedzicha, J.A.1
Calverley, P.M.2
Seemungal, T.A.3
-
36
-
-
84865284777
-
Concurrent use of indacaterol plus tiotropium in patients with COPD provides superior bronchodilation compared with tiotropium alone: A randomised, double-blind comparison
-
Mahler DA, D'Urzo A, Bateman ED, et al. Concurrent use of indacaterol plus tiotropium in patients with COPD provides superior bronchodilation compared with tiotropium alone: a randomised, double-blind comparison. Thorax 2012; 67: 781-788.
-
(2012)
Thorax
, vol.67
, pp. 781-788
-
-
Mahler, D.A.1
D'Urzo, A.2
Bateman, E.D.3
-
37
-
-
77957254369
-
Indacaterol provides 24-hour bronchodilation in COPD: A placebo-controlled blinded comparison with tiotropium
-
Vogelmeier C, Ramos-Barbon D, Jack D, et al. Indacaterol provides 24-hour bronchodilation in COPD: a placebo-controlled blinded comparison with tiotropium. Respir Res 2010; 11: 135.
-
(2010)
Respir Res
, vol.11
, pp. 135
-
-
Vogelmeier, C.1
Ramos-Barbon, D.2
Jack, D.3
-
38
-
-
80053090797
-
Blinded 12-week comparison of once-daily indacaterol and tiotropium in COPD
-
Buhl R, Dunn LJ, Disdier C, et al. Blinded 12-week comparison of once-daily indacaterol and tiotropium in COPD. Eur Respir J 2011; 38: 797-803.
-
(2011)
Eur Respir J
, vol.38
, pp. 797-803
-
-
Buhl, R.1
Dunn, L.J.2
Disdier, C.3
-
39
-
-
77954800883
-
Once-daily bronchodilators for chronic obstructive pulmonary disease: Indacaterol versus tiotropium
-
Donohue JF, Fogarty C, Lotvall J, et al. Once-daily bronchodilators for chronic obstructive pulmonary disease: indacaterol versus tiotropium. Am J Respir Crit Care Med 2010; 182: 155-162.
-
(2010)
Am J Respir Crit Care Med
, vol.182
, pp. 155-162
-
-
Donohue, J.F.1
Fogarty, C.2
Lotvall, J.3
-
40
-
-
84877131237
-
Analysis of chronic obstructive pulmonary disease exacerbations with the dual bronchodilator QVA149 compared with glycopyrronium and tiotropium (SPARK): A randomised, double-blind, parallel-group study
-
Wedzicha JA, Decramer M, Ficker JH, et al. Analysis of chronic obstructive pulmonary disease exacerbations with the dual bronchodilator QVA149 compared with glycopyrronium and tiotropium (SPARK): a randomised, double-blind, parallel-group study. Lancet Respir Med 2013; 1: 199-209.
-
(2013)
Lancet Respir Med
, vol.1
, pp. 199-209
-
-
Wedzicha, J.A.1
Decramer, M.2
Ficker, J.H.3
-
41
-
-
82955248100
-
Acute effects of indacaterol on lung hyperinflation in moderate COPD: A comparison with tiotropium
-
Rossi A, Centanni S, Cerveri I, et al. Acute effects of indacaterol on lung hyperinflation in moderate COPD: a comparison with tiotropium. Respir Med 2012; 106: 84-90.
-
(2012)
Respir Med
, vol.106
, pp. 84-90
-
-
Rossi, A.1
Centanni, S.2
Cerveri, I.3
-
42
-
-
84906049219
-
Long-acting inhaled therapy (beta-agonists, anticholinergics and steroids) for COPD: A network meta-analysis
-
Kew KM, Dias S, Cates CJ. Long-acting inhaled therapy (beta-agonists, anticholinergics and steroids) for COPD: a network meta-analysis. Cochrane Database Syst Rev 2014; 3: CD010844.
-
(2014)
Cochrane Database Syst Rev
, vol.3
-
-
Kew, K.M.1
Dias, S.2
Cates, C.J.3
-
43
-
-
84901766003
-
Efficacy and safety of umeclidinium plus vilanterol versus tiotropium, vilanterol, or umeclidinium monotherapies over 24 weeks in patients with chronic obstructive pulmonary disease: Results from two multicentre, blinded, randomised controlled trials
-
Decramer M, Anzueto A, Kerwin E, et al. Efficacy and safety of umeclidinium plus vilanterol versus tiotropium, vilanterol, or umeclidinium monotherapies over 24 weeks in patients with chronic obstructive pulmonary disease: results from two multicentre, blinded, randomised controlled trials. Lancet Respir Med 2014; 2: 472-486.
-
(2014)
Lancet Respir Med
, vol.2
, pp. 472-486
-
-
Decramer, M.1
Anzueto, A.2
Kerwin, E.3
-
44
-
-
84877126115
-
Once-daily inhaled fluticasone furoate and vilanterol versus vilanterol only for prevention of exacerbations of COPD: Two replicate double-blind, parallel-group, randomised controlled trials
-
Dransfield MT, Bourbeau J, Jones PW, et al. Once-daily inhaled fluticasone furoate and vilanterol versus vilanterol only for prevention of exacerbations of COPD: two replicate double-blind, parallel-group, randomised controlled trials. Lancet Respir Med 2013; 1: 210-223.
-
(2013)
Lancet Respir Med
, vol.1
, pp. 210-223
-
-
Dransfield, M.T.1
Bourbeau, J.2
Jones, P.W.3
-
45
-
-
70349854706
-
Efficacy and tolerability of budesonide/formoterol added to tiotropium in patients with chronic obstructive pulmonary disease
-
Welte T, Miravitlles M, Hernandez P, et al. Efficacy and tolerability of budesonide/formoterol added to tiotropium in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2009; 180: 741-750.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 741-750
-
-
Welte, T.1
Miravitlles, M.2
Hernandez, P.3
-
46
-
-
84907779764
-
Withdrawal of inhaled glucocorticoids and exacerbations of COPD
-
Magnussen H, Disse B, Rodriguez-Roisin R, et al. Withdrawal of inhaled glucocorticoids and exacerbations of COPD. N Engl J Med 2014; 371: 1285-1294.
-
(2014)
N Engl J Med
, vol.371
, pp. 1285-1294
-
-
Magnussen, H.1
Disse, B.2
Rodriguez-Roisin, R.3
-
47
-
-
69149103642
-
Roflumilast in symptomatic chronic obstructive pulmonary disease: Two randomised clinical trials
-
Calverley PM, Rabe KF, Goehring UM, et al. Roflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trials. Lancet 2009; 374: 685-694.
-
(2009)
Lancet
, vol.374
, pp. 685-694
-
-
Calverley, P.M.1
Rabe, K.F.2
Goehring, U.M.3
-
48
-
-
84877589288
-
Efficacy of roflumilast in the COPD frequent exacerbator phenotype
-
Wedzicha JA, Rabe KF, Martinez FJ, et al. Efficacy of roflumilast in the COPD frequent exacerbator phenotype. Chest 2013; 143: 1302-1311.
-
(2013)
Chest
, vol.143
, pp. 1302-1311
-
-
Wedzicha, J.A.1
Rabe, K.F.2
Martinez, F.J.3
-
49
-
-
84871698675
-
Does roflumilast decrease exacerbations in severe COPD patients not controlled by inhaled combination therapy? The REACT study protocol
-
Calverley PM, Martinez FJ, Fabbri LM, et al. Does roflumilast decrease exacerbations in severe COPD patients not controlled by inhaled combination therapy? The REACT study protocol. Int J Chron Obstruct Pulmon Dis 2012; 7: 375-382.
-
(2012)
Int J Chron Obstruct Pulmon Dis
, vol.7
, pp. 375-382
-
-
Calverley, P.M.1
Martinez, F.J.2
Fabbri, L.M.3
-
50
-
-
56749157688
-
Long-term erythromycin therapy is associated with decreased chronic obstructive pulmonary disease exacerbations
-
Seemungal TA, Wilkinson TM, Hurst JR, et al. Long-term erythromycin therapy is associated with decreased chronic obstructive pulmonary disease exacerbations. Am J Respir Crit Care Med 2008; 178: 1139-1147.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 1139-1147
-
-
Seemungal, T.A.1
Wilkinson, T.M.2
Hurst, J.R.3
-
51
-
-
80052157895
-
Azithromycin for prevention of exacerbations of COPD
-
Albert RK, Connett J, Bailey WC, et al. Azithromycin for prevention of exacerbations of COPD. N Engl J Med 2011; 365: 689-698.
-
(2011)
N Engl J Med
, vol.365
, pp. 689-698
-
-
Albert, R.K.1
Connett, J.2
Bailey, W.C.3
-
52
-
-
77952490797
-
Pulsed moxifloxacin for the prevention of exacerbations of chronic obstructive pulmonary disease: A randomized controlled trial
-
Sethi S, Jones PW, Theron MS, et al. Pulsed moxifloxacin for the prevention of exacerbations of chronic obstructive pulmonary disease: a randomized controlled trial. Respir Res 2010; 11: 10.
-
(2010)
Respir Res
, vol.11
, pp. 10
-
-
Sethi, S.1
Jones, P.W.2
Theron, M.S.3
-
53
-
-
84861076083
-
Azithromycin and the risk of cardiovascular death
-
Ray WA, Murray KT, Hall K, et al. Azithromycin and the risk of cardiovascular death. N Engl J Med 2012; 366: 1881-1890.
-
(2012)
N Engl J Med
, vol.366
, pp. 1881-1890
-
-
Ray, W.A.1
Murray, K.T.2
Hall, K.3
-
54
-
-
84877120597
-
Risks of population antimicrobial resistance associated with chronic macrolide use for inflammatory airway diseases
-
Serisier DJ. Risks of population antimicrobial resistance associated with chronic macrolide use for inflammatory airway diseases. Lancet Respir Med 2013; 1: 262-274.
-
(2013)
Lancet Respir Med
, vol.1
, pp. 262-274
-
-
Serisier, D.J.1
-
55
-
-
84902665590
-
Predictors of chronic obstructive pulmonary disease exacerbation reduction in response to daily azithromycin therapy
-
Han MK, Tayob N, Murray S, et al. Predictors of chronic obstructive pulmonary disease exacerbation reduction in response to daily azithromycin therapy. Am J Respir Crit Care Med 2014; 189: 1503-1508.
-
(2014)
Am J Respir Crit Care Med
, vol.189
, pp. 1503-1508
-
-
Han, M.K.1
Tayob, N.2
Murray, S.3
-
56
-
-
72849144086
-
Mortality in the 4-year trial of tiotropium (UPLIFT) in patients with chronic obstructive pulmonary disease
-
Celli B, Decramer M, Kesten S, et al. Mortality in the 4-year trial of tiotropium (UPLIFT) in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2009; 180: 948-955.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 948-955
-
-
Celli, B.1
Decramer, M.2
Kesten, S.3
-
57
-
-
48949103222
-
Effect of pharmacotherapy on rate of decline of lung function in chronic obstructive pulmonary disease: Results from the TORCH study
-
Celli BR, Thomas NE, Anderson JA, et al. Effect of pharmacotherapy on rate of decline of lung function in chronic obstructive pulmonary disease: results from the TORCH study. Am J Respir Crit Care Med 2008; 178: 332-338.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 332-338
-
-
Celli, B.R.1
Thomas, N.E.2
Anderson, J.A.3
-
58
-
-
77954650588
-
Tiotropium as a first maintenance drug in COPD: Secondary analysis of the UPLIFT trial
-
Troosters T, Celli B, Lystig T, et al. Tiotropium as a first maintenance drug in COPD: secondary analysis of the UPLIFT trial. Eur Respir J 2010; 36: 65-73.
-
(2010)
Eur Respir J
, vol.36
, pp. 65-73
-
-
Troosters, T.1
Celli, B.2
Lystig, T.3
-
59
-
-
84862582008
-
Spirometric predictors of lung function decline and mortality in early chronic obstructive pulmonary disease
-
Drummond MB, Hansel NN, Connett JE, et al. Spirometric predictors of lung function decline and mortality in early chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2012; 185: 1301-1306.
-
(2012)
Am J Respir Crit Care Med
, vol.185
, pp. 1301-1306
-
-
Drummond, M.B.1
Hansel, N.N.2
Connett, J.E.3
-
60
-
-
84874997685
-
Seasonal distribution of COPD exacerbations in the Prevention of Exacerbations with Tiotropium in COPD trial
-
Rabe KF, Fabbri LM, Vogelmeier C, et al. Seasonal distribution of COPD exacerbations in the Prevention of Exacerbations with Tiotropium in COPD trial. Chest 2013; 143: 711-719.
-
(2013)
Chest
, vol.143
, pp. 711-719
-
-
Rabe, K.F.1
Fabbri, L.M.2
Vogelmeier, C.3
-
61
-
-
78650278281
-
Bias due to withdrawal in long-term randomised trials in COPD: Evidence from the TORCH study
-
Vestbo J, Anderson JA, Calverley PM, et al. Bias due to withdrawal in long-term randomised trials in COPD: evidence from the TORCH study. Clin Respir J 2011; 5: 44-49.
-
(2011)
Clin Respir J
, vol.5
, pp. 44-49
-
-
Vestbo, J.1
Anderson, J.A.2
Calverley, P.M.3
-
62
-
-
79957634460
-
Health status in the TORCH study of COPD: Treatment efficacy and other determinants of change
-
Jones PW, Anderson JA, Calverley PMA, et al. Health status in the TORCH study of COPD: treatment efficacy and other determinants of change. Respir Res 2011; 12: 71.
-
(2011)
Respir Res
, vol.12
, pp. 71
-
-
Jones, P.W.1
Anderson, J.A.2
Calverley, P.M.A.3
-
63
-
-
84891372240
-
Effect of ADRB2 polymorphisms on the efficacy of salmeterol and tiotropium in preventing COPD exacerbations: A prespecified substudy of the POET-COPD trial
-
Rabe KF, Fabbri LM, Israel E, et al. Effect of ADRB2 polymorphisms on the efficacy of salmeterol and tiotropium in preventing COPD exacerbations: a prespecified substudy of the POET-COPD trial. Lancet Respir Med 2014; 2: 44-53.
-
(2014)
Lancet Respir Med
, vol.2
, pp. 44-53
-
-
Rabe, K.F.1
Fabbri, L.M.2
Israel, E.3
-
64
-
-
73149110829
-
Prevalence and progression of osteoporosis in patients with COPD: Results from the TOwards a Revolution in COPD Health study
-
Ferguson GT, Calverley PM, Anderson JA, et al. Prevalence and progression of osteoporosis in patients with COPD: results from the TOwards a Revolution in COPD Health study. Chest 2009; 136: 1456-1465.
-
(2009)
Chest
, vol.136
, pp. 1456-1465
-
-
Ferguson, G.T.1
Calverley, P.M.2
Anderson, J.A.3
-
65
-
-
70349088498
-
Pneumonia risk in COPD patients receiving inhaled corticosteroids alone or in combination: TORCH study results
-
Crim C, Calverley PM, Anderson JA, et al. Pneumonia risk in COPD patients receiving inhaled corticosteroids alone or in combination: TORCH study results. Eur Respir J 2009; 34: 641-647.
-
(2009)
Eur Respir J
, vol.34
, pp. 641-647
-
-
Crim, C.1
Calverley, P.M.2
Anderson, J.A.3
-
66
-
-
77957586919
-
Reported pneumonia in patients with COPD: Findings from the INSPIRE study
-
Calverley PM, Stockley RA, Seemungal TA, et al. Reported pneumonia in patients with COPD: findings from the INSPIRE study. Chest 2011; 139: 505-512.
-
(2011)
Chest
, vol.139
, pp. 505-512
-
-
Calverley, P.M.1
Stockley, R.A.2
Seemungal, T.A.3
-
67
-
-
69149110944
-
Budesonide and the risk of pneumonia: A meta-analysis of individual patient data
-
Sin DD, Tashkin D, Zhang X, et al. Budesonide and the risk of pneumonia: a meta-analysis of individual patient data. Lancet 2009; 374: 712-719.
-
(2009)
Lancet
, vol.374
, pp. 712-719
-
-
Sin, D.D.1
Tashkin, D.2
Zhang, X.3
-
68
-
-
84879713090
-
2 agonist: Observational matched cohort study (PATHOS)
-
2 agonist: observational matched cohort study (PATHOS). BMJ 2013; 346: f3306.
-
(2013)
BMJ
, vol.346
-
-
Janson, C.1
Larsson, K.2
Lisspers, K.H.3
-
69
-
-
84900408808
-
Risk of pneumonia with inhaled corticosteroid/long-acting β2 agonist therapy in chronic obstructive pulmonary disease: A cluster analysis
-
DiSantostefano RL, Li H, Hinds D, et al. Risk of pneumonia with inhaled corticosteroid/long-acting β2 agonist therapy in chronic obstructive pulmonary disease: a cluster analysis. Int J Chron Obstruct Pulmon Dis 2014; 9: 457-468.
-
(2014)
Int J Chron Obstruct Pulmon Dis
, vol.9
, pp. 457-468
-
-
DiSantostefano, R.L.1
Li, H.2
Hinds, D.3
-
70
-
-
77956052751
-
Cardiovascular events in patients with COPD: TORCH study results
-
Calverley PM, Anderson JA, Celli B, et al. Cardiovascular events in patients with COPD: TORCH study results. Thorax 2010; 65: 719-725.
-
(2010)
Thorax
, vol.65
, pp. 719-725
-
-
Calverley, P.M.1
Anderson, J.A.2
Celli, B.3
-
71
-
-
69449088107
-
Tiotropium and risk for fatal and nonfatal cardiovascular events in patients with chronic obstructive pulmonary disease: Systematic review with meta-analysis
-
Rodrigo GJ, Castro-Rodriguez JA, Nannini LJ, et al. Tiotropium and risk for fatal and nonfatal cardiovascular events in patients with chronic obstructive pulmonary disease: systematic review with meta-analysis. Respir Med 2009; 103: 1421-1429.
-
(2009)
Respir Med
, vol.103
, pp. 1421-1429
-
-
Rodrigo, G.J.1
Castro-Rodriguez, J.A.2
Nannini, L.J.3
-
72
-
-
84859008802
-
Mortality associated with tiotropium mist inhaler in patients with chronic obstructive pulmonary disease: Systematic review and meta-analysis of randomised controlled trials
-
Singh S, Loke YK, Enright PL, et al. Mortality associated with tiotropium mist inhaler in patients with chronic obstructive pulmonary disease: systematic review and meta-analysis of randomised controlled trials. BMJ 2011; 342: d3215.
-
(2011)
BMJ
, vol.342
-
-
Singh, S.1
Loke, Y.K.2
Enright, P.L.3
-
73
-
-
69149098943
-
Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: Two randomised clinical trials
-
Fabbri LM, Calverley PM, Izquierdo-Alonso JL, et al. Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: two randomised clinical trials. Lancet 2009; 374: 695-703.
-
(2009)
Lancet
, vol.374
, pp. 695-703
-
-
Fabbri, L.M.1
Calverley, P.M.2
Izquierdo-Alonso, J.L.3
-
74
-
-
79551603829
-
Characterisation of COPD heterogeneity in the ECLIPSE cohort
-
Agusti A, Calverley PM, Celli B, et al. Characterisation of COPD heterogeneity in the ECLIPSE cohort. Respir Res 2010; 11: 122.
-
(2010)
Respir Res
, vol.11
, pp. 122
-
-
Agusti, A.1
Calverley, P.M.2
Celli, B.3
-
75
-
-
77949363490
-
Genetic epidemiology of COPD (COPDGene) study design
-
Regan EA, Hokanson JE, Murphy JR, et al. Genetic epidemiology of COPD (COPDGene) study design. COPD 2010; 7: 32-43.
-
(2010)
COPD
, vol.7
, pp. 32-43
-
-
Regan, E.A.1
Hokanson, J.E.2
Murphy, J.R.3
-
76
-
-
78650210969
-
Loci identified by genome-wide association studies influence different disease-related phenotypes in chronic obstructive pulmonary disease
-
Pillai SG, Kong X, Edwards LD, et al. Loci identified by genome-wide association studies influence different disease-related phenotypes in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2010; 182: 1498-1505.
-
(2010)
Am J Respir Crit Care Med
, vol.182
, pp. 1498-1505
-
-
Pillai, S.G.1
Kong, X.2
Edwards, L.D.3
-
77
-
-
77956689733
-
Susceptibility to exacerbation in chronic obstructive pulmonary disease
-
Hurst JR, Vestbo J, Anzueto A, et al. Susceptibility to exacerbation in chronic obstructive pulmonary disease. N Engl J Med 2010; 363: 1128-1138.
-
(2010)
N Engl J Med
, vol.363
, pp. 1128-1138
-
-
Hurst, J.R.1
Vestbo, J.2
Anzueto, A.3
-
78
-
-
84899784758
-
Should we view chronic obstructive pulmonary disease differently after ECLIPSE? A clinical perspective from the study team
-
Vestbo J, Agusti A, Wouters EF, et al. Should we view chronic obstructive pulmonary disease differently after ECLIPSE? A clinical perspective from the study team. Am J Respir Crit Care Med 2014; 189: 1022-1030.
-
(2014)
Am J Respir Crit Care Med
, vol.189
, pp. 1022-1030
-
-
Vestbo, J.1
Agusti, A.2
Wouters, E.F.3
-
79
-
-
84902164334
-
Lessons from ECLIPSE: A review of COPD biomarkers
-
Faner R, Tal-Singer R, Riley JH, et al. Lessons from ECLIPSE: a review of COPD biomarkers. Thorax 2014; 69: 666-672.
-
(2014)
Thorax
, vol.69
, pp. 666-672
-
-
Faner, R.1
Tal-Singer, R.2
Riley, J.H.3
-
80
-
-
80053350305
-
Changes in forced expiratory volume in 1 second over time in COPD
-
Vestbo J, Edwards LD, Scanlon PD, et al. Changes in forced expiratory volume in 1 second over time in COPD. N Engl J Med 2011; 365: 1184-1192.
-
(2011)
N Engl J Med
, vol.365
, pp. 1184-1192
-
-
Vestbo, J.1
Edwards, L.D.2
Scanlon, P.D.3
-
81
-
-
84878642324
-
The presence and progression of emphysema in COPD as determined by CT scanning and biomarker expression: A prospective analysis from the ECLIPSE study
-
Coxson HO, Dirksen A, Edwards LD, et al. The presence and progression of emphysema in COPD as determined by CT scanning and biomarker expression: a prospective analysis from the ECLIPSE study. Lancet Respir Med 2013; 1: 129-136.
-
(2013)
Lancet Respir Med
, vol.1
, pp. 129-136
-
-
Coxson, H.O.1
Dirksen, A.2
Edwards, L.D.3
-
82
-
-
84873956600
-
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary
-
Vestbo J, Hurd SS, Agusti AG, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 2013; 187: 347-365.
-
(2013)
Am J Respir Crit Care Med
, vol.187
, pp. 347-365
-
-
Vestbo, J.1
Hurd, S.S.2
Agusti, A.G.3
-
83
-
-
80053058518
-
Chronic obstructive pulmonary disease exacerbations in the COPDGene study: Associated radiologic phenotypes
-
Han MK, Kazerooni EA, Lynch DA, et al. Chronic obstructive pulmonary disease exacerbations in the COPDGene study: associated radiologic phenotypes. Radiology 2011; 261: 274-282.
-
(2011)
Radiology
, vol.261
, pp. 274-282
-
-
Han, M.K.1
Kazerooni, E.A.2
Lynch, D.A.3
-
84
-
-
84865683260
-
Pulmonary arterial enlargement and acute exacerbations of COPD
-
Wells JM, Washko GR, Han MK, et al. Pulmonary arterial enlargement and acute exacerbations of COPD. N Engl J Med 2012; 367: 913-921.
-
(2012)
N Engl J Med
, vol.367
, pp. 913-921
-
-
Wells, J.M.1
Washko, G.R.2
Han, M.K.3
-
85
-
-
57649120097
-
The modified BODE index: Validation with mortality in COPD
-
Cote CG, Pinto-Plata VM, Marin JM, et al. The modified BODE index: validation with mortality in COPD. Eur Respir J 2008; 32: 1269-1274.
-
(2008)
Eur Respir J
, vol.32
, pp. 1269-1274
-
-
Cote, C.G.1
Pinto-Plata, V.M.2
Marin, J.M.3
-
86
-
-
84861410475
-
Inflammatory biomarkers improve clinical prediction of mortality in chronic obstructive pulmonary disease
-
Celli BR, Locantore N, Yates J, et al. Inflammatory biomarkers improve clinical prediction of mortality in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2012; 185: 1065-1072.
-
(2012)
Am J Respir Crit Care Med
, vol.185
, pp. 1065-1072
-
-
Celli, B.R.1
Locantore, N.2
Yates, J.3
-
87
-
-
84873946521
-
Six-minute-walk test in chronic obstructive pulmonary disease: Minimal clinically important difference for death or hospitalization
-
Polkey MI, Spruit MA, Edwards LD, et al. Six-minute-walk test in chronic obstructive pulmonary disease: minimal clinically important difference for death or hospitalization. Am J Respir Crit Care Med 2013; 187: 382-386.
-
(2013)
Am J Respir Crit Care Med
, vol.187
, pp. 382-386
-
-
Polkey, M.I.1
Spruit, M.A.2
Edwards, L.D.3
-
88
-
-
58149401115
-
Interpretation of treatment changes in 6-minute walk distance in patients with COPD
-
Puhan MA, Mador MJ, Held U, et al. Interpretation of treatment changes in 6-minute walk distance in patients with COPD. Eur Respir J 2008; 32: 637-643.
-
(2008)
Eur Respir J
, vol.32
, pp. 637-643
-
-
Puhan, M.A.1
Mador, M.J.2
Held, U.3
-
89
-
-
84878867004
-
Inflammatory biomarkers and exacerbations in chronic obstructive pulmonary disease
-
Thomsen M, Ingebrigtsen TS, Marott JL, et al. Inflammatory biomarkers and exacerbations in chronic obstructive pulmonary disease. JAMA 2013; 309: 2353-2361.
-
(2013)
JAMA
, vol.309
, pp. 2353-2361
-
-
Thomsen, M.1
Ingebrigtsen, T.S.2
Marott, J.L.3
-
90
-
-
79954630909
-
Molecular mechanisms of inflammation during exacerbations of chronic obstructive pulmonary disease
-
Kersul AL, Iglesias A, Rios A, et al. Molecular mechanisms of inflammation during exacerbations of chronic obstructive pulmonary disease. Arch Bronconeumol 2011; 47: 176-183.
-
(2011)
Arch Bronconeumol
, vol.47
, pp. 176-183
-
-
Kersul, A.L.1
Iglesias, A.2
Rios, A.3
-
91
-
-
84862100999
-
Persistent systemic inflammation is associated with poor clinical outcomes in COPD: A novel phenotype
-
Agusti A, Edwards LD, Rennard SI, et al. Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype. PLoS One 2012; 7: e37483.
-
(2012)
PLoS One
, vol.7
-
-
Agusti, A.1
Edwards, L.D.2
Rennard, S.I.3
-
92
-
-
0033910486
-
The heterogeneity of chronic obstructive pulmonary disease
-
Wedzicha JA. The heterogeneity of chronic obstructive pulmonary disease. Thorax 2000; 55: 631-632.
-
(2000)
Thorax
, vol.55
, pp. 631-632
-
-
Wedzicha, J.A.1
-
93
-
-
53749083607
-
COPD and declining FEV1 - Time to divide and conquer?
-
Reilly JJ. COPD and declining FEV1 - time to divide and conquer? N Engl J Med 2008; 359: 1616-1618.
-
(2008)
N Engl J Med
, vol.359
, pp. 1616-1618
-
-
Reilly, J.J.1
-
94
-
-
69249105428
-
Time to define the disorders of the syndrome of COPD
-
Beasley R, Weatherall M, Travers J, et al. Time to define the disorders of the syndrome of COPD. Lancet 2009; 374: 670-672.
-
(2009)
Lancet
, vol.374
, pp. 670-672
-
-
Beasley, R.1
Weatherall, M.2
Travers, J.3
-
95
-
-
56249083570
-
Prevalence and outcomes of diabetes, hypertension and cardiovascular disease in COPD
-
Mannino DM, Thorn D, Swensen A, et al. Prevalence and outcomes of diabetes, hypertension and cardiovascular disease in COPD. Eur Respir J 2008; 32: 962-969.
-
(2008)
Eur Respir J
, vol.32
, pp. 962-969
-
-
Mannino, D.M.1
Thorn, D.2
Swensen, A.3
-
96
-
-
84895469127
-
Comorbidities in patients with COPD and pulmonary rehabilitation: Do they matter?
-
Franssen FM, Rochester CL. Comorbidities in patients with COPD and pulmonary rehabilitation: do they matter? Eur Respir Rev 2014; 23: 131-141.
-
(2014)
Eur Respir Rev
, vol.23
, pp. 131-141
-
-
Franssen, F.M.1
Rochester, C.L.2
-
98
-
-
84879735745
-
Characteristics, stability and outcomes of the 2011 GOLD COPD groups in the ECLIPSE cohort
-
Agusti A, Edwards LD, Celli B, et al. Characteristics, stability and outcomes of the 2011 GOLD COPD groups in the ECLIPSE cohort. Eur Respir J 2013; 42: 636-646.
-
(2013)
Eur Respir J
, vol.42
, pp. 636-646
-
-
Agusti, A.1
Edwards, L.D.2
Celli, B.3
-
99
-
-
84887311230
-
The ABCD of GOLD made clear
-
Calverley PM. The ABCD of GOLD made clear. Eur Respir J 2013; 42: 1163-1165.
-
(2013)
Eur Respir J
, vol.42
, pp. 1163-1165
-
-
Calverley, P.M.1
-
100
-
-
84887279386
-
FAQs about the GOLD 2011 assessment proposal of COPD: A comparative analysis of four different cohorts
-
Agusti A, Hurd S, Jones P, et al. FAQs about the GOLD 2011 assessment proposal of COPD: a comparative analysis of four different cohorts. Eur Respir J 2013; 42: 1391-1401.
-
(2013)
Eur Respir J
, vol.42
, pp. 1391-1401
-
-
Agusti, A.1
Hurd, S.2
Jones, P.3
-
101
-
-
84885766455
-
Inhaled corticosteroids in COPD and the risk of serious pneumonia
-
Suissa S, Patenaude V, Lapi F, et al. Inhaled corticosteroids in COPD and the risk of serious pneumonia. Thorax 2013; 68: 1029-1036.
-
(2013)
Thorax
, vol.68
, pp. 1029-1036
-
-
Suissa, S.1
Patenaude, V.2
Lapi, F.3
-
102
-
-
79960201163
-
Impact of inhaled corticosteroid use on outcome in COPD patients admitted with pneumonia
-
Singanayagam A, Chalmers JD, Akram AR, et al. Impact of inhaled corticosteroid use on outcome in COPD patients admitted with pneumonia. Eur Respir J 2011; 38: 36-41.
-
(2011)
Eur Respir J
, vol.38
, pp. 36-41
-
-
Singanayagam, A.1
Chalmers, J.D.2
Akram, A.R.3
-
103
-
-
84883495199
-
Use of tiotropium Respimat Soft Mist Inhaler versus HandiHaler and mortality in patients with COPD
-
Verhamme KM, Afonso A, Romio S, et al. Use of tiotropium Respimat Soft Mist Inhaler versus HandiHaler and mortality in patients with COPD. Eur Respir J 2013; 42: 606-615.
-
(2013)
Eur Respir J
, vol.42
, pp. 606-615
-
-
Verhamme, K.M.1
Afonso, A.2
Romio, S.3
-
104
-
-
84922394855
-
FEV1 decline in patients with chronic obstructive pulmonary disease associated with biomass exposure
-
Ramirez-Venegas A, Sansores RH, Quintana-Carrillo RH, et al. FEV1 decline in patients with chronic obstructive pulmonary disease associated with biomass exposure. Am J Respir Crit Care Med 2014; 190: 996-1002.
-
(2014)
Am J Respir Crit Care Med
, vol.190
, pp. 996-1002
-
-
Ramirez-Venegas, A.1
Sansores, R.H.2
Quintana-Carrillo, R.H.3
-
105
-
-
84907216438
-
Blood eosinophil guided prednisolone therapy for exacerbations of COPD: A further analysis
-
Bafadhel M, Davies L, Calverley PM, et al. Blood eosinophil guided prednisolone therapy for exacerbations of COPD: a further analysis. Eur Respir J 2014; 44: 789-791.
-
(2014)
Eur Respir J
, vol.44
, pp. 789-791
-
-
Bafadhel, M.1
Davies, L.2
Calverley, P.M.3
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