FTY720 mitigates torsion/detorsion-induced testicular injury in rats

Journal of Surgical Research

Volumn 196, Issue 2, 2015, Pages 325-331

  Shih, Hung Jen ^a,b   Yen, Jiin Cherng ^b   Chiu, Allen W ^b   Chow, Yung Chiong ^c,d   Pan, Wynn H T ^b   Wang, Tao Yeuan ^c   Huang, Chun Jen ^e,f  

^a CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c MACKAY MEMORIAL HOSPITAL   (Taiwan)

^d MACKAY MEDICAL COLLEGE   (Taiwan)

^e Taipei Ren Chi Hospital   (Taiwan)

^f TZU CHI UNIVERSITY   (Taiwan)

Author keywords

Ischemia; Reperfusion; Sphingosine 1 phosphate; Testis; Torsion

Indexed keywords

2 AMINO 2 (3 OCTYLPHENYLCARBAMOYL)ETHYL PHOSPHATE; FINGOLIMOD; INTERLEUKIN 1BETA; MALONALDEHYDE; MYELOPEROXIDASE; SODIUM CHLORIDE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; IMMUNOSUPPRESSIVE AGENT; PROPANEDIOL DERIVATIVE; SPHINGOSINE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRY WEIGHT; EDEMA; ENZYME ACTIVITY; HISTOPATHOLOGY; IMMUNOFLUORESCENCE TEST; LIQUID CHROMATOGRAPHY; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; RAT; SHAM PROCEDURE; TANDEM MASS SPECTROMETRY; TESTIS DETORSION; TESTIS INJURY; TESTIS TORSION; WET TO DRY WEIGHT RATIO; YOUNG ADULT; ANALOGS AND DERIVATIVES; ANIMAL; DRUG EFFECTS; DRUG SCREENING; INFLAMMATION; INJURIES; LIPID METABOLISM; METABOLISM; RANDOMIZATION; SPERMATIC CORD TORSION; SPRAGUE DAWLEY RAT; TESTIS;

ANIMALS; DRUG EVALUATION, PRECLINICAL; EDEMA; IMMUNOSUPPRESSIVE AGENTS; INFLAMMATION; LIPID METABOLISM; MALE; NEUTROPHIL INFILTRATION; PROPYLENE GLYCOLS; RANDOM ALLOCATION; RATS, SPRAGUE-DAWLEY; SPERMATIC CORD TORSION; SPHINGOSINE; TESTIS;

EID: 84930382758     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2015.03.014     Document Type: Article

References (36)

1. M.L. Blank, P.J. O'Neill, and C.K. Steigman Reperfusion injury following testicular torsion and detorsion in prepubertal rats Urol Res 21 1993 389
2. D.G. DaJusta, C.F. Granberg, C. Villanueva, and L.A. Baker Contemporary review of testicular torsion: new concepts, emerging technologies and potential therapeutics J Pediatr Urol 9 2013 723
3. H.K. Eltzschig, and T. Eckle Ischemia and reperfusion-from mechanism to translation Nat Med 17 2011 1391
4. T.T. Turner, H.J. Bang, and J.L. Lysiak The molecular pathology of experimental testicular torsion suggests adjunct therapy to surgical repair J Urol 172 2004 2574
5. T.T. Turner, K.S. Tung, H. Tomomasa, and L.W. Wilson Acute testicular ischemia results in germ cell-specific apoptosis in the rat Biol Reprod 57 1997 1267
6. A.J. Visser, and C.F. Heyns Testicular function after torsion of the spermatic cord BJU Int 92 2003 200
7. S. Shimizu, R. Oikawa, and P. Tsounapi Blocking of the ATP sensitive potassium channel ameliorates the ischaemia-reperfusion injury in the rat testis Andrology 2 2014 458
8. P. Tsounapi, M. Saito, and F. Dimitriadis Antioxidant treatment with edaravone or taurine ameliorates diabetes-induced testicular dysfunction in the rat Mol Cell Biochem 369 2012 195
9. P. Tsounapi, M. Saito, and F. Dimitriadis Protective effect of sivelestat, a neutrophil elastase inhibitor, on ipsilateral and contralateral testes after unilateral testicular ischaemia-reperfusion injury in rats BJU Int 107 2011 329
10. T. Kono, M. Saito, Y. Kinoshita, I. Satoh, C. Shinbori, and K. Satoh Real-time monitoring of nitric oxide and blood flow during ischemia-reperfusion in the rat testis Mol Cell Biochem 286 2006 139
11. S. Yang, H.J. Shih, and Y.C. Chow The protective role of heme oxygenase-1 induction on testicular tissues after testicular torsion and detorsion J Urol 177 2007 1928
12. S. Yang, H.J. Shih, Y.C. Chow, T.Y. Wang, P.S. Tsai, and C.J. Huang Simvastatin attenuates testicular injury induced by torsion-detorsion J Urol 184 2010 750
13. G.M. Strub, M. Maceyka, N.C. Hait, S. Milstien, and S. Spiegel Extracellular and intracellular actions of sphingosine-1-phosphate Adv Exp Med Biol 688 2010 141
14. K. Takabe, S.W. Paugh, S. Milstien, and S. Spiegel "Inside-out" signaling of sphingosine-1-phosphate: therapeutic targets Pharmacol Rev 60 2008 181
15. H. Fyrst, and J.D. Saba An update on sphingosine-1-phosphate and other sphingolipid mediators Nat Chem Biol 6 2010 489
16. S.K. Jo, A. Bajwa, A.S. Awad, K.R. Lynch, and M.D. Okusa Sphingosine-1-phosphate receptors: biology and therapeutic potential in kidney disease Kidney Int 73 2008 1220
17. C.H. Liu, and T. Hla The mouse gene for the inducible G-protein-coupled receptor edg-1 Genomics 43 1997 15
18. D. Papadopoulos, J. Rundle, and R. Patel FTY720 ameliorates MOG-induced experimental autoimmune encephalomyelitis by suppressing both cellular and humoral immune responses J Neurosci Res 88 2010 346
19. A.S. Awad, H. Ye, and L. Huang Selective sphingosine 1-phosphate 1 receptor activation reduces ischemia-reperfusion injury in mouse kidney Am J Physiol Ren Physiol 290 2006 F1516
20. G. Galicia-Rosas, N. Pikor, and J.A. Schwartz A sphingosine-1-phosphate receptor 1-directed agonist reduces central nervous system inflammation in a plasmacytoid dendritic cell-dependent manner J Immunol 189 2012 3700
21. U. Hofmann, N. Burkard, and C. Vogt Protective effects of sphingosine-1-phosphate receptor agonist treatment after myocardial ischaemia-reperfusion Cardiovasc Res 83 2009 285
22. A. Billich, F. Bornancin, P. Devay, D. Mechtcheriakova, N. Urtz, and T. Baumruker Phosphorylation of the immunomodulatory drug FTY720 by sphingosine kinases J Biol Chem 278 2003 47408
23. A. Bajwa, S.K. Jo, and H. Ye Activation of sphingosine-1-phosphate 1 receptor in the proximal tubule protects against ischemia-reperfusion injury J Am Soc Nephrol 21 2010 955
24. D. Marsolais, S. Yagi, T. Kago, N. Leaf, and H. Rosen Modulation of chemokines and allergic airway inflammation by selective local sphingosine-1-phosphate receptor 1 agonism in lungs Mol Pharmacol 79 2011 61
25. V. Natarajan, S.M. Dudek, and J.R. Jacobson Sphingosine-1-phosphate, FTY720 and sphingosine-1-phosphate receptors in the pathobiology of acute lung injury Am J Respir Cell Mol Biol 49 2013 6
26. N. Ferreiros, S. Labocha, M. Schroder, H.H. Radeke, and G. Geisslinger LC-MS/MS determination of FTY720 and FTY720-phosphate in murine intracellular compartments and human plasma J Chromatogr B Analyt Technol Biomed Life Sci 887-888 2012 122
27. M.J. Cosentino, M. Nishida, R. Rabinowitz, and A.T. Cockett Histological changes occurring in the contralateral testes of prepubertal rats subjected to various durations of unilateral spermatic cord torsion J Urol 133 1985 906
28. E. Roberts, M. Guerrero, M. Urbano, and H. Rosen Sphingosine 1-phosphate receptor agonists: a patent review (2010-2012) Expert Opin Ther Pat 23 2013 817
29. C. Gasperini, and S. Ruggieri Development of oral agent in the treatment of multiple sclerosis: how the first available oral therapy, fingolimod will change therapeutic paradigm approach Drug Des Devel Ther 6 2012 175
30. L.W. Lai, K.C. Yong, S. Igarashi, and Y.H. Lien A sphingosine-1-phosphate type 1 receptor agonist inhibits the early T-cell transient following renal ischemia-reperfusion injury Kidney Int 71 2007 1223
31. D. Marsolais, and H. Rosen Chemical modulators of sphingosine-1-phosphate receptors as barrier-oriented therapeutic molecules Nat Rev Drug Discov 8 2009 297
32. M. Kim, M. Kim, S.W. Park, S.M. Pitson, and H.T. Lee Isoflurane protects human kidney proximal tubule cells against necrosis via sphingosine kinase and sphingosine-1-phosphate generation Am J Nephrol 31 2010 353
33. S.F. Rodrigues, and D.N. Granger Role of blood cells in ischaemia-reperfusion induced endothelial barrier failure Cardiovasc Res 87 2010 291
34. A. Groves, Y. Kihara, and J. Chun Fingolimod: direct CNS effects of sphingosine 1-phosphate (S1P) receptor modulation and implications in multiple sclerosis therapy J Neurol Sci 328 2013 9
35. A. Bajwa, D.L. Rosin, and P. Chroscicki Sphingosine 1-Phosphate Receptor-1 enhances mitochondrial function and reduces cisplatin-induced tubule injury J Am Soc Nephrol 26 2015 908
36. A.M. Khalid, A. Asano, Y.Z. Hosaka, K. Ohyama, M. Ohta, and Y. Yamano Expression of a novel sphingosine 1-phosphate receptor motif protein gene in maturing rat testes Biosci Biotechnol Biochem 76 2012 1769