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Volumn 39, Issue 7, 2015, Pages 779-785

Hypoxia regulates proliferation of acute myeloid leukemia and sensitivity against chemotherapy

Author keywords

Acute myeloid leukemia; Bone marrow; Cell cycle; Chemotherapy; Hypoxia

Indexed keywords

CYTARABINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P27; VASCULOTROPIN; X LINKED INHIBITOR OF APOPTOSIS; ANTINEOPLASTIC AGENT;

EID: 84930382597     PISSN: 01452126     EISSN: 18735835     Source Type: Journal    
DOI: 10.1016/j.leukres.2015.04.019     Document Type: Article
Times cited : (43)

References (24)
  • 1
    • 84878372012 scopus 로고    scopus 로고
    • Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia
    • May (22)
    • Cancer Genome Atlas Research N. Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. N Engl J Med 2013, 368(May (22)):2059-2074.
    • (2013) N Engl J Med , vol.368 , pp. 2059-2074
    • Cancer Genome Atlas Research, N.1
  • 2
    • 0035885955 scopus 로고    scopus 로고
    • The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials
    • September (6)
    • Kottaridis P.D., Gale R.E., Frew M.E., Harrison G., Langabeer S.E., Belton A.A., et al. The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials. Blood 2001, 98(September (6)):1752-1759.
    • (2001) Blood , vol.98 , pp. 1752-1759
    • Kottaridis, P.D.1    Gale, R.E.2    Frew, M.E.3    Harrison, G.4    Langabeer, S.E.5    Belton, A.A.6
  • 3
    • 77449159028 scopus 로고    scopus 로고
    • Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet
    • January (3)
    • Dohner H., Estey E.H., Amadori S., Appelbaum F.R., Buchner T., Burnett A.K., et al. Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet. Blood 2010, 115(January (3)):453-474.
    • (2010) Blood , vol.115 , pp. 453-474
    • Dohner, H.1    Estey, E.H.2    Amadori, S.3    Appelbaum, F.R.4    Buchner, T.5    Burnett, A.K.6
  • 4
    • 0036659931 scopus 로고    scopus 로고
    • Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease
    • July (1)
    • Schnittger S., Schoch C., Dugas M., Kern W., Staib P., Wuchter C., et al. Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease. Blood 2002, 100(July (1)):59-66.
    • (2002) Blood , vol.100 , pp. 59-66
    • Schnittger, S.1    Schoch, C.2    Dugas, M.3    Kern, W.4    Staib, P.5    Wuchter, C.6
  • 5
    • 84886534519 scopus 로고    scopus 로고
    • Sorafenib in combination with intensive chemotherapy in elderly patients with acute myeloid leukemia: results from a randomized, placebo-controlled trial
    • September (25)
    • Serve H., Krug U., Wagner R., Sauerland M.C., Heinecke A., Brunnberg U., et al. Sorafenib in combination with intensive chemotherapy in elderly patients with acute myeloid leukemia: results from a randomized, placebo-controlled trial. J Clin Oncol 2013, 31(September (25)):3110-3118.
    • (2013) J Clin Oncol , vol.31 , pp. 3110-3118
    • Serve, H.1    Krug, U.2    Wagner, R.3    Sauerland, M.C.4    Heinecke, A.5    Brunnberg, U.6
  • 6
    • 74949089659 scopus 로고    scopus 로고
    • Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction
    • January (1)
    • Samudio I., Harmancey R., Fiegl M., Kantarjian H., Konopleva M., Korchin B., et al. Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction. J Clin Investig 2010, 120(January (1)):142-156.
    • (2010) J Clin Investig , vol.120 , pp. 142-156
    • Samudio, I.1    Harmancey, R.2    Fiegl, M.3    Kantarjian, H.4    Konopleva, M.5    Korchin, B.6
  • 7
    • 0036738149 scopus 로고    scopus 로고
    • Stromal cells prevent apoptosis of AML cells by up-regulation of anti-apoptotic proteins
    • September (9)
    • Konopleva M., Konoplev S., Hu W., Zaritskey A.Y., Afanasiev B.V., Andreeff M. Stromal cells prevent apoptosis of AML cells by up-regulation of anti-apoptotic proteins. Leukemia 2002, 16(September (9)):1713-1724.
    • (2002) Leukemia , vol.16 , pp. 1713-1724
    • Konopleva, M.1    Konoplev, S.2    Hu, W.3    Zaritskey, A.Y.4    Afanasiev, B.V.5    Andreeff, M.6
  • 8
    • 77951040369 scopus 로고    scopus 로고
    • Metabolism and the leukemic stem cell
    • April (4)
    • Abdel-Wahab O., Levine R.L. Metabolism and the leukemic stem cell. J Exp Med 2010, 207(April (4)):677-680.
    • (2010) J Exp Med , vol.207 , pp. 677-680
    • Abdel-Wahab, O.1    Levine, R.L.2
  • 9
    • 34248359065 scopus 로고    scopus 로고
    • Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia
    • March (13)
    • Parmar K., Mauch P., Vergilio J.A., Sackstein R., Down J.D. Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia. Proc Natl Acad Sci U S A 2007, 104(March (13)):5431-5436.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 5431-5436
    • Parmar, K.1    Mauch, P.2    Vergilio, J.A.3    Sackstein, R.4    Down, J.D.5
  • 10
    • 61849173436 scopus 로고    scopus 로고
    • CXCR4 expression and biologic activity in acute myeloid leukemia are dependent on oxygen partial pressure
    • February (7)
    • Fiegl M., Samudio I., Clise-Dwyer K., Burks J.K., Mnjoyan Z., Andreeff M. CXCR4 expression and biologic activity in acute myeloid leukemia are dependent on oxygen partial pressure. Blood 2009, 113(February (7)):1504-1512.
    • (2009) Blood , vol.113 , pp. 1504-1512
    • Fiegl, M.1    Samudio, I.2    Clise-Dwyer, K.3    Burks, J.K.4    Mnjoyan, Z.5    Andreeff, M.6
  • 11
    • 5044230101 scopus 로고    scopus 로고
    • CD25 indicates the neoplastic phenotype of mast cells: a novel immunohistochemical marker for the diagnosis of systemic mastocytosis (SM) in routinely processed bone marrow biopsy specimens
    • October (10)
    • Sotlar K., Horny H.P., Simonitsch I., Krokowski M., Aichberger K.J., Mayerhofer M., et al. CD25 indicates the neoplastic phenotype of mast cells: a novel immunohistochemical marker for the diagnosis of systemic mastocytosis (SM) in routinely processed bone marrow biopsy specimens. Am J Surg Pathol 2004, 28(October (10)):1319-1325.
    • (2004) Am J Surg Pathol , vol.28 , pp. 1319-1325
    • Sotlar, K.1    Horny, H.P.2    Simonitsch, I.3    Krokowski, M.4    Aichberger, K.J.5    Mayerhofer, M.6
  • 12
    • 84907303242 scopus 로고    scopus 로고
    • Isolated trisomy 13 defines a genetically homogenous AML subgroup with high frequency of mutations in spliceosome genes and poor prognosis
    • June
    • Herold T., Metzeler K.H., Vosberg S., Hartmann L., Rollig C., Stolzel F., et al. Isolated trisomy 13 defines a genetically homogenous AML subgroup with high frequency of mutations in spliceosome genes and poor prognosis. Blood 2014, 12(June).
    • (2014) Blood , vol.12
    • Herold, T.1    Metzeler, K.H.2    Vosberg, S.3    Hartmann, L.4    Rollig, C.5    Stolzel, F.6
  • 13
    • 84875999131 scopus 로고    scopus 로고
    • Identification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study
    • March (9)
    • Li Z., Herold T., He C., Valk P.J., Chen P., Jurinovic V., et al. Identification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study. J Clin Oncol 2013, 31(March (9)):1172-1181.
    • (2013) J Clin Oncol , vol.31 , pp. 1172-1181
    • Li, Z.1    Herold, T.2    He, C.3    Valk, P.J.4    Chen, P.5    Jurinovic, V.6
  • 14
    • 33745003472 scopus 로고    scopus 로고
    • Double induction containing either two courses or one course of high-dose cytarabine plus mitoxantrone and postremission therapy by either autologous stem-cell transplantation or by prolonged maintenance for acute myeloid leukemia
    • June (16)
    • Buchner T., Berdel W.E., Schoch C., Haferlach T., Serve H.L., Kienast J., et al. Double induction containing either two courses or one course of high-dose cytarabine plus mitoxantrone and postremission therapy by either autologous stem-cell transplantation or by prolonged maintenance for acute myeloid leukemia. J Clin Oncol 2006, 24(June (16)):2480-2489.
    • (2006) J Clin Oncol , vol.24 , pp. 2480-2489
    • Buchner, T.1    Berdel, W.E.2    Schoch, C.3    Haferlach, T.4    Serve, H.L.5    Kienast, J.6
  • 15
    • 79954591044 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1alpha protein expression is associated with poor survival in normal karyotype adult acute myeloid leukemia
    • Deeb G., Vaughan M.M., McInnis I., Ford L.A., Sait S.N., Starostik P., et al. Hypoxia-inducible factor-1alpha protein expression is associated with poor survival in normal karyotype adult acute myeloid leukemia. Leuk Res 2011, 35(5):579-584.
    • (2011) Leuk Res , vol.35 , Issue.5 , pp. 579-584
    • Deeb, G.1    Vaughan, M.M.2    McInnis, I.3    Ford, L.A.4    Sait, S.N.5    Starostik, P.6
  • 16
    • 79954625804 scopus 로고    scopus 로고
    • Hypoxia and expression of hypoxia-related proteins in acute myeloid leukemia
    • Fiegl M., Spiekermann K. Hypoxia and expression of hypoxia-related proteins in acute myeloid leukemia. Leuk Res 2011, 35(5):573-574.
    • (2011) Leuk Res , vol.35 , Issue.5 , pp. 573-574
    • Fiegl, M.1    Spiekermann, K.2
  • 17
    • 84915733840 scopus 로고    scopus 로고
    • HIF-1alpha can act as a tumor suppressor gene in murine acute myeloid leukemia
    • December (24)
    • Velasco-Hernandez T., Hyrenius-Wittsten A., Rehn M., Bryder D., Cammenga J. HIF-1alpha can act as a tumor suppressor gene in murine acute myeloid leukemia. Blood 2014, 124(December (24)):3597-3607.
    • (2014) Blood , vol.124 , pp. 3597-3607
    • Velasco-Hernandez, T.1    Hyrenius-Wittsten, A.2    Rehn, M.3    Bryder, D.4    Cammenga, J.5
  • 18
    • 34447616779 scopus 로고    scopus 로고
    • Oxygen saturation in the bone marrow of healthy volunteers
    • January (1)
    • Harrison J.S., Rameshwar P., Chang V., Bandari P. Oxygen saturation in the bone marrow of healthy volunteers. Blood 2002, 99(January (1)):394.
    • (2002) Blood , vol.99 , pp. 394
    • Harrison, J.S.1    Rameshwar, P.2    Chang, V.3    Bandari, P.4
  • 19
    • 80053916176 scopus 로고    scopus 로고
    • Metabolic regulation of hematopoietic stem cells in the hypoxic niche
    • October (4)
    • Suda T., Takubo K., Semenza G.L. Metabolic regulation of hematopoietic stem cells in the hypoxic niche. Cell Stem Cell 2011, 9(October (4)):298-310.
    • (2011) Cell Stem Cell , vol.9 , pp. 298-310
    • Suda, T.1    Takubo, K.2    Semenza, G.L.3
  • 20
    • 77954661120 scopus 로고    scopus 로고
    • Physiological hypoxia promotes lipid raft and PI3K-dependent activation of MAPK 42/44 in leukemia cells
    • July (7)
    • Fiegl M., Samudio I., Mnjoyan Z., Korchin B., Fritsche H., Andreeff M. Physiological hypoxia promotes lipid raft and PI3K-dependent activation of MAPK 42/44 in leukemia cells. Leukemia 2010, 24(July (7)):1364-1367.
    • (2010) Leukemia , vol.24 , pp. 1364-1367
    • Fiegl, M.1    Samudio, I.2    Mnjoyan, Z.3    Korchin, B.4    Fritsche, H.5    Andreeff, M.6
  • 21
    • 0032587495 scopus 로고    scopus 로고
    • P27kip1: a multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers
    • Lloyd R.V., Erickson L.A., Jin L., Kulig E., Qian X., Cheville J.C., et al. p27kip1: a multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers. Am J Pathol 1999, 154(2):313-323.
    • (1999) Am J Pathol , vol.154 , Issue.2 , pp. 313-323
    • Lloyd, R.V.1    Erickson, L.A.2    Jin, L.3    Kulig, E.4    Qian, X.5    Cheville, J.C.6
  • 22
    • 0033900808 scopus 로고    scopus 로고
    • The pharmacodynamic basis for the increased antileukaemic efficacy of cytosine arabinoside-based treatment regimens in acute myeloid leukaemia with a high proliferative activity
    • July (1)
    • Braess J., Voss S., Jahns-Streubel G., Schoch C., Haferlach T., Kern W., et al. The pharmacodynamic basis for the increased antileukaemic efficacy of cytosine arabinoside-based treatment regimens in acute myeloid leukaemia with a high proliferative activity. Br J Haematol 2000, 110(July (1)):170-179.
    • (2000) Br J Haematol , vol.110 , pp. 170-179
    • Braess, J.1    Voss, S.2    Jahns-Streubel, G.3    Schoch, C.4    Haferlach, T.5    Kern, W.6
  • 23
    • 0042967809 scopus 로고    scopus 로고
    • Effect of priming with granulocyte colony-stimulating factor on the outcome of chemotherapy for acute myeloid leukemia
    • August (8)
    • Lowenberg B., van Putten W., Theobald M., Gmur J., Verdonck L., Sonneveld P., et al. Effect of priming with granulocyte colony-stimulating factor on the outcome of chemotherapy for acute myeloid leukemia. N Engl J Med 2003, 349(August (8)):743-752.
    • (2003) N Engl J Med , vol.349 , pp. 743-752
    • Lowenberg, B.1    van Putten, W.2    Theobald, M.3    Gmur, J.4    Verdonck, L.5    Sonneveld, P.6
  • 24
    • 84890312785 scopus 로고    scopus 로고
    • PI3K inhibitor GDC-0941 enhances apoptotic effects of BH-3 mimetic ABT-737 in AML cells in the hypoxic bone marrow microenvironment
    • December (12)
    • Jin L., Tabe Y., Kojima K., Shikami M., Benito J., Ruvolo V., et al. PI3K inhibitor GDC-0941 enhances apoptotic effects of BH-3 mimetic ABT-737 in AML cells in the hypoxic bone marrow microenvironment. J Mol Med 2013, 91(December (12)):1383-1397.
    • (2013) J Mol Med , vol.91 , pp. 1383-1397
    • Jin, L.1    Tabe, Y.2    Kojima, K.3    Shikami, M.4    Benito, J.5    Ruvolo, V.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.