N-Formyl peptides drive mitochondrial damage associated molecular pattern induced neutrophil activation through ERK1/2 and P38 MAP kinase signalling pathways

Injury

Volumn 46, Issue 6, 2015, Pages 975-984

  Hazeldine, Jon ^a   Hampson, Peter ^a,b   Opoku, Francis Adusei ^b   Foster, Mark ^b   Lord, Janet M ^a  

^a UNIVERSITY DEPARTMENT OF MEDICINE   (United Kingdom)

^b QUEEN ELIZABETH HOSPITAL   (United Kingdom)

Author keywords

Mitochondrial damage associated molecular patterns; Mitogen activated protein kinases; Neutrophils; Trauma

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CYCLOSPORIN H; INTERLEUKIN 8; L SELECTIN; MITOCHONDRIAL DNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; N FORMYL PEPTIDE; PEPTIDE; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; IL8 PROTEIN, HUMAN; MITOCHONDRIAL PROTEIN; TNF PROTEIN, HUMAN; TUMOR NECROSIS FACTOR;

ARTICLE; CELL DAMAGE; CELL DENSITY; CELL ISOLATION; CELL STIMULATION; CELL SURFACE; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOKINE RELEASE; DAMAGE ASSOCIATED MOLECULAR PATTERN; DEGRANULATION; DEGRANULATION ASSAY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; LEUKOCYTE ACTIVATION; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING; COMPLICATION; IMMUNOLOGY; METABOLISM; NEUTROPHIL; PATHOLOGY; PHOSPHORYLATION; SIGNAL TRANSDUCTION; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; WOUNDS AND INJURIES;

HUMANS; INTERLEUKIN-8; L-SELECTIN; MAP KINASE SIGNALING SYSTEM; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NEUTROPHIL ACTIVATION; NEUTROPHILS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; SIGNAL TRANSDUCTION; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; TUMOR NECROSIS FACTOR-ALPHA; WOUNDS AND INJURIES;

EID: 84930377656     PISSN: 00201383     EISSN: 18790267     Source Type: Journal    
DOI: 10.1016/j.injury.2015.03.028     Document Type: Article

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