Tumor bed radiosurgery: an emerging treatment for brain metastases

Journal of Neuro-Oncology

Volumn 123, Issue 2, 2015, Pages 197-203

  Amsbaugh, Mark J ^a   Boling, Warren ^a   Woo, Shiao ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

Brain metastases; Post operative radiosurgery; Radiosurgery

Indexed keywords

ANTICONVULSIVE AGENT; STEROID;

ADJUVANT CHEMOTHERAPY; BRAIN FUNCTION; BRAIN METASTASIS; CANCER MORTALITY; CANCER RADIOTHERAPY; COGNITION; COMPARATIVE EFFECTIVENESS; DISEASE COURSE; DRUG TOLERABILITY; FRACTIONATED STEREOTACTIC RADIOSURGERY; HEALTH CARE QUALITY; HUMAN; MARGIN; MEDICAL INFORMATION; MORBIDITY; NEUROLOGIC DISEASE; ONCOLOGICAL PARAMETERS; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); POSTOPERATIVE PERIOD; QUALITY OF LIFE; RADIATION DOSE; RADIATION DOSE FRACTIONATION; RADIATION NECROSIS; REVIEW; STEREOTACTIC BODY RADIATION THERAPY; STEREOTACTIC RADIOSURGERY; SURGICAL TECHNIQUE; TREATMENT FAILURE; TUMOR BED RADIOSURGERY; TUMOR VOLUME; WHOLE BRAIN RADIATION THERAPY; BRAIN NEOPLASMS; RADIOSURGERY; SECONDARY;

BRAIN NEOPLASMS; HUMANS; RADIOSURGERY;

EID: 84930377020     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-015-1789-y     Document Type: Review

References (46)

1. Nayak L, Lee EQ, Wen PY (2012) Epidemiology of brain metastases. Curr Oncol Rep 14(1):48–54. doi:10.1007/s11912-011-0203-y
2. Takakura K (1982) Metastatic tumors of the central nervous system. Igaku-Shoin, Tokyo
3. Andrews DW, Scott CB, Sperduto PW, Flanders AE, Gaspar LE, Schell MC, Werner-Wasik M, Demas W, Ryu J, Bahary J-P, Souhami L, Rotman M, Mehta MP, Curran WJ (2004) Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: phase III results of the RTOG 9508 randomised trial. Lancet 363(9422):1665–1672. doi:10.1016/s0140-6736(04)16250-8
4. Noordijk EM, Vecht CJ, Haaxma-Reiche H, Padberg GW, Voormolen JH, Hoekstra FH, Tans JT, Lambooij N, Metsaars JA, Wattendorff AR et al (1994) The choice of treatment of single brain metastasis should be based on extracranial tumor activity and age. Int J Radiat Oncol Biol Phys 29(4):711–717
5. Patchell RA, Tibbs PA, Walsh JW, Dempsey RJ, Maruyama Y, Kryscio RJ, Markesbery WR, Macdonald JS, Young B (1990) A randomized trial of surgery in the treatment of single metastases to the brain. N Engl J Med 322(8):494–500. doi:10.1056/nejm199002223220802
6. Fabi A, Felici A, Metro G, Mirri A, Bria E, Telera S, Moscetti L, Russillo M, Lanzetta G, Mansueto G, Pace A, Maschio M, Vidiri A, Sperduti I, Cognetti F, Carapella CM (2011) Brain metastases from solid tumors: disease outcome according to type of treatment and therapeutic resources of the treating center. J Exp Clin Cancer Res 30:10. doi:10.1186/1756-9966-30-10
7. Nussbaum ES, Djalilian HR, Cho KH, Hall WA (1996) Brain metastases. Histology, multiplicity, surgery, and survival. Cancer 78(8):1781–1788
8. Aoyama H, Shirato H, Tago M, Nakagawa K, Toyoda T, Hatano K, Kenjyo M, Oya N, Hirota S, Shioura H, Kunieda E, Inomata T, Hayakawa K, Katoh N, Kobashi G (2006) Stereotactic radiosurgery plus whole-brain radiation therapy vs stereotactic radiosurgery alone for treatment of brain metastases: a randomized controlled trial. JAMA, J Am Med Assoc 295(21):2483–2491. doi:10.1001/jama.295.21.2483
9. Chang EL, Wefel JS, Hess KR, Allen PK, Lang FF, Kornguth DG, Arbuckle RB, Swint JM, Shiu AS, Maor MH, Meyers CA (2009) Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irradiation: a randomised controlled trial. Lancet Oncol 10(11):1037–1044. doi:10.1016/s1470-2045(09)70263-3
10. Kocher M, Soffietti R, Abacioglu U, Villa S, Fauchon F, Baumert BG, Fariselli L, Tzuk-Shina T, Kortmann RD, Carrie C, Ben Hassel M, Kouri M, Valeinis E, van den Berge D, Collette S, Collette L, Mueller RP (2011) Adjuvant whole-brain radiotherapy versus observation after radiosurgery or surgical resection of one to three cerebral metastases: results of the EORTC 22952-26001 study. J Clin Oncol: Off J Am Soc Clin Oncol 29(2):134–141. doi:10.1200/JCO.2010.30.1655
11. O’Neill BP, Iturria NJ, Link MJ, Pollock BE, Ballman KV, O’Fallon JR (2003) A comparison of surgical resection and stereotactic radiosurgery in the treatment of solitary brain metastases. Int J Radiat Oncol Biol Phys 55(5):1169–1176. doi:10.1016/s0360-3016(02)04379-1
12. Patchell RA, Tibbs PA, Regine WF, Dempsey RJ, Mohiuddin M, Kryscio RJ, Markesbery WR, Foon KA, Young B (1998) Postoperative radiotherapy in the treatment of single metastases to the brain: a randomized trial. JAMA, J Am Med Assoc 280(17):1485–1489
13. Gans JH, Raper DM, Shah AH, Bregy A, Heros D, Lally BE, Morcos JJ, Heros RC, Komotar RJ (2013) The role of radiosurgery to the tumor bed after resection of brain metastases. Neurosurgery 72(3):317–325. doi:10.1227/NEU.0b013e31827fcd60. discussion 325–316
14. Kelly PJ, Lin YB, Yu AY, Alexander BM, Hacker F, Marcus KJ, Weiss SE (2012) Stereotactic irradiation of the postoperative resection cavity for brain metastasis: a frameless linear accelerator-based case series and review of the technique. Int J Radiat Oncol Biol Phys 82(1):95–101. doi:10.1016/j.ijrobp.2010.10.043
15. Roberge D, Parney I, Brown PD (2012) Radiosurgery to the postoperative surgical cavity: who needs evidence? Int J Radiat Oncol Biol Phys 83(2):486–493. doi:10.1016/j.ijrobp.2011.09.032
16. Roberge D, Souhami L (2010) Tumor bed radiosurgery following resection of brain metastases: a review. Technol Cancer Res Treat 9(6):597–602
17. Minniti G, Esposito V, Clarke E, Scaringi C, Lanzetta G, Salvati M, Raco A, Bozzao A, Enrici RM (2013) Multidose stereotactic radiosurgery (9 Gy × 3) of the postoperative resection cavity for treatment of large brain metastases. Int J Radiat Oncol Biol Phys 86(4):623–629. doi:10.1016/j.ijrobp.2013.03.037
18. Steinmann D, Maertens B, Janssen S, Werner M, Fruhauf J, Nakamura M, Christiansen H, Bremer M (2012) Hypofractionated stereotactic radiotherapy (hfSRT) after tumour resection of a single brain metastasis: report of a single-centre individualized treatment approach. J Cancer Res Clin Oncol 138(9):1523–1529. doi:10.1007/s00432-012-1227-x
19. Wang CC, Floyd SR, Chang CH, Warnke PC, Chio CC, Kasper EM, Mahadevan A, Wong ET, Chen CC (2012) Cyberknife hypofractionated stereotactic radiosurgery (HSRS) of resection cavity after excision of large cerebral metastasis: efficacy and safety of an 800 cGy × 3 daily fractions regimen. J Neurooncol 106(3):601–610. doi:10.1007/s11060-011-0697-z
20. Asher AL, Burri SH, Wiggins WF, Kelly RP, Boltes MO, Mehrlich M, Norton HJ, Fraser RW (2014) A new treatment paradigm: neoadjuvant radiosurgery before surgical resection of brain metastases with analysis of local tumor recurrence. Int J Radiat Oncol Biol Phys 88(4):899–906. doi:10.1016/j.ijrobp.2013.12.013
21. Choi CY, Chang SD, Gibbs IC, Adler JR, Harsh GRt, Atalar B, Lieberson RE, Soltys SG (2012) What is the optimal treatment of large brain metastases? An argument for a multidisciplinary approach. Int J Radiat Oncol Biol Phys 84(3):688–693. doi:10.1016/j.ijrobp.2012.01.028
22. Choi CY, Chang SD, Gibbs IC, Adler JR, Harsh GRt, Lieberson RE, Soltys SG (2012) Stereotactic radiosurgery of the postoperative resection cavity for brain metastases: prospective evaluation of target margin on tumor control. Int J Radiat Oncol Biol Phys 84(2):336–342. doi:10.1016/j.ijrobp.2011.12.009
23. Do L, Pezner R, Radany E, Liu A, Staud C, Badie B (2009) Resection followed by stereotactic radiosurgery to resection cavity for intracranial metastases. Int J Radiat Oncol Biol Phys 73(2):486–491. doi:10.1016/j.ijrobp.2008.04.070
24. Hartford AC, Paravati AJ, Spire WJ, Li Z, Jarvis LA, Fadul CE, Rhodes CH, Erkmen K, Friedman J, Gladstone DJ, Hug EB, Roberts DW, Simmons NE (2013) Postoperative stereotactic radiosurgery without whole-brain radiation therapy for brain metastases: potential role of preoperative tumor size. Int J Radiat Oncol Biol Phys 85(3):650–655. doi:10.1016/j.ijrobp.2012.05.027
25. Hwang SW, Abozed MM, Hale A, Eisenberg RL, Dvorak T, Yao K, Pfannl R, Mignano J, Zhu JJ, Price LL, Strauss GM, Wu JK (2010) Adjuvant Gamma Knife radiosurgery following surgical resection of brain metastases: a 9-year retrospective cohort study. J Neurooncol 98(1):77–82. doi:10.1007/s11060-009-0051-x
26. Iwai Y, Yamanaka K, Yasui T (2008) Boost radiosurgery for treatment of brain metastases after surgical resections. Surg Neurol 69(2):181–186. doi:10.1016/j.surneu.2007.07.008. discussion 186
27. Jagannathan J, Yen CP, Ray DK, Schlesinger D, Oskouian RJ, Pouratian N, Shaffrey ME, Larner J, Sheehan JP (2009) Gamma Knife radiosurgery to the surgical cavity following resection of brain metastases. J Neurosurg 111(3):431–438. doi:10.3171/2008.11.jns08818
28. Jensen CA, Chan MD, McCoy TP, Bourland JD, deGuzman AF, Ellis TL, Ekstrand KE, McMullen KP, Munley MT, Shaw EG, Urbanic JJ, Tatter SB (2011) Cavity-directed radiosurgery as adjuvant therapy after resection of a brain metastasis. J Neurosurg 114(6):1585–1591. doi:10.3171/2010.11.jns10939
29. Karlovits BJ, Quigley MR, Karlovits SM, Miller L, Johnson M, Gayou O, Fuhrer R (2009) Stereotactic radiosurgery boost to the resection bed for oligometastatic brain disease: challenging the tradition of adjuvant whole-brain radiotherapy. Neurosurg Focus 27(6):E7. doi:10.3171/2009.9.focus09191
30. Limbrick DD Jr, Lusis EA, Chicoine MR, Rich KM, Dacey RG, Dowling JL, Grubb RL, Filiput EA, Drzymala RE, Mansur DB, Simpson JR (2009) Combined surgical resection and stereotactic radiosurgery for treatment of cerebral metastases. Surg Neurol 71(3):280–288. doi:10.1016/j.surneu.2007.12.019. disucssion 288–289
31. Luther N, Kondziolka D, Kano H, Mousavi SH, Engh JA, Niranjan A, Flickinger JC, Lunsford LD (2013) Predicting tumor control after resection bed radiosurgery of brain metastases. Neurosurgery 73(6):1001–1006. doi:10.1227/neu.0000000000000148. discussion 1006
32. Mathieu D, Kondziolka D, Flickinger JC, Fortin D, Kenny B, Michaud K, Mongia S, Niranjan A, Lunsford LD (2008) Tumor bed radiosurgery after resection of cerebral metastases. Neurosurgery 62(4):817–823. doi:10.1227/01.neu.0000316899.55501.8b. discussion 823–814
33. Ogiwara H, Kalakota K, Rakhra SS, Helenowski IB, Marymont MH, Kalapurakal JA, Mehta MP, Levy RB, Chandler JP (2012) Intracranial relapse rates and patterns, and survival trends following post-resection cavity radiosurgery for patients with single intracranial metastases. J Neurooncol 108(1):141–146. doi:10.1007/s11060-012-0808-5
34. Prabhu R, Shu HK, Hadjipanayis C, Dhabaan A, Hall W, Raore B, Olson J, Curran W, Oyesiku N, Crocker I (2012) Current dosing paradigm for stereotactic radiosurgery alone after surgical resection of brain metastases needs to be optimized for improved local control. Int J Radiat Oncol Biol Phys 83(1):e61–e66. doi:10.1016/j.ijrobp.2011.12.017
35. Quigley MR, Fuhrer R, Karlovits S, Karlovits B, Johnson M (2008) Single session stereotactic radiosurgery boost to the post-operative site in lieu of whole brain radiation in metastatic brain disease. J Neurooncol 87(3):327–332. doi:10.1007/s11060-007-9515-z
36. Robbins JR, Ryu S, Kalkanis S, Cogan C, Rock J, Movsas B, Kim JH, Rosenblum M (2012) Radiosurgery to the surgical cavity as adjuvant therapy for resected brain metastasis. Neurosurgery 71(5):937–943. doi:10.1227/NEU.0b013e31826909f2
37. Soltys SG, Adler JR, Lipani JD, Jackson PS, Choi CY, Puataweepong P, White S, Gibbs IC, Chang SD (2008) Stereotactic radiosurgery of the postoperative resection cavity for brain metastases. Int J Radiat Oncol Biol Phys 70(1):187–193. doi:10.1016/j.ijrobp.2007.06.068
38. Roberge D, Petrecca K, El Refae M, Souhami L (2009) Whole-brain radiotherapy and tumor bed radiosurgery following resection of solitary brain metastases. J Neurooncol 95(1):95–99. doi:10.1007/s11060-009-9899-z
39. Kim PK, Ellis TL, Stieber VW, McMullen KP, Shaw EG, McCoy TP, D’Agostino RB, Bourland JD, DeGuzman AF, Ekstrand KE, Raber MR, Tatter SB (2006) Gamma Knife surgery targeting the resection cavity of brain metastasis that has progressed after whole-brain radiotherapy. J Neurosurg 105(Suppl):75–78. doi:10.3171/sup.2006.105.7.75
40. Brennan C, Yang TJ, Hilden P, Zhang Z, Chan K, Yamada Y, Chan TA, Lymberis SC, Narayana A, Tabar V, Gutin PH, Ballangrud A, Lis E, Beal K (2014) A phase 2 trial of stereotactic radiosurgery boost after surgical resection for brain metastases. Int J Radiat Oncol Biol Phys 88(1):130–136. doi:10.1016/j.ijrobp.2013.09.051
41. Shaw E, Scott C, Souhami L, Dinapoli R, Kline R, Loeffler J, Farnan N (2000) Single dose radiosurgical treatment of recurrent previously irradiated primary brain tumors and brain metastases: final report of RTOG protocol 90-05. Int J Radiat Oncol Biol Phys 47(2):291–298
42. Atalar B, Choi CY, Harsh GRt, Chang SD, Gibbs IC, Adler JR, Soltys SG (2013) Cavity volume dynamics after resection of brain metastases and timing of postresection cavity stereotactic radiosurgery. Neurosurgery 72(2):180–185. doi:10.1227/NEU.0b013e31827b99f3. discussion 185
43. Jarvis LA, Simmons NE, Bellerive M, Erkmen K, Eskey CJ, Gladstone DJ, Hug EB, Roberts DW, Hartford AC (2012) Tumor bed dynamics after surgical resection of brain metastases: implications for postoperative radiosurgery. Int J Radiat Oncol Biol Phys 84(4):943–948. doi:10.1016/j.ijrobp.2012.01.067
44. Berghoff AS, Rajky O, Winkler F, Bartsch R, Furtner J, Hainfellner JA, Goodman SL, Weller M, Schittenhelm J, Preusser M (2013) Invasion patterns in brain metastases of solid cancers. Neuro-oncology 15(12):1664–1672. doi:10.1093/neuonc/not112
45. Rogers LR, Rock JP, Sills AK, Vogelbaum MA, Suh JH, Ellis TL, Stieber VW, Asher AL, Fraser RW, Billingsley JS, Lewis P, Schellingerhout D, Shaw EG (2006) Results of a phase II trial of the GliaSite radiation therapy system for the treatment of newly diagnosed, resected single brain metastases. J Neurosurg 105(3):375–384. doi:10.3171/jns.2006.105.3.375
46. Ma L, Sahgal A, Larson DA, Pinnaduwage D, Fogh S, Barani I, Nakamura J, McDermott M, Sneed P (2014) Impact of millimeter-level margins on peripheral normal brain sparing for gamma knife radiosurgery. Int J Radiat Oncol Biol Phys 89(1):206–213. doi:10.1016/j.ijrobp.2014.01.011