What is the optimal treatment of large brain metastases? An argument for a multidisciplinary approach

International Journal of Radiation Oncology Biology Physics

Volumn 84, Issue 3, 2012, Pages 688-693

  Choi, Clara Y H ^a   Chang, Steven D ^a   Gibbs, Iris C ^a   Adler, John R ^a   Harsh IV, Griffith R ^a   Atalar, Banu ^b   Lieberson, Robert E ^a   Soltys, Scott G ^a,c  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^b ACIBADEM UNIVERSITY   (Turkey)

^c STANFORD CANCER INSTITUTE   (United States)

Author keywords

Brain metastases; Cavity; CyberKnife; Postoperative; Stereotactic radiosurgery

Indexed keywords

BRAIN METASTASIS; CAVITY; CYBERKNIFE; POSTOPERATIVE; STEREOTACTIC RADIOSURGERY;

BRAIN; IRRADIATION; PESTICIDE EFFECTS; RADIOTHERAPY; REGRESSION ANALYSIS; SURGERY;

POPULATION STATISTICS;

ADULT; AGED; ARTICLE; BRAIN DYSFUNCTION; BRAIN METASTASIS; CANCER ADJUVANT THERAPY; CANCER CONTROL; CANCER MORTALITY; CANCER SURGERY; CANCER SURVIVAL; EDEMA; FEMALE; FOLLOW UP; HUMAN; KARNOFSKY PERFORMANCE STATUS; MAJOR CLINICAL STUDY; MALE; MULTIMODALITY CANCER THERAPY; NEUROIMAGING; OVERALL SURVIVAL; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; RADIATION NECROSIS; RETROSPECTIVE STUDY; RISK ASSESSMENT; STEREOTACTIC RADIOSURGERY; SURVIVAL TIME; TUMOR VOLUME;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BRAIN NEOPLASMS; COMBINED MODALITY THERAPY; CRANIAL IRRADIATION; FEMALE; HUMANS; KAPLAN-MEIER ESTIMATE; KARNOFSKY PERFORMANCE STATUS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; RADIOSURGERY; RADIOTHERAPY, ADJUVANT; SURVIVAL RATE; TUMOR BURDEN; YOUNG ADULT;

EID: 84866728298     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2012.01.028     Document Type: Article

References (24)

1. C. Nieder, W. Berberich, and K. Schnabel Tumor-related prognostic factors for remission of brain metastases after radiotherapy Int J Radiat Oncol Biol Phys 39 1997 25 30
2. E. Shaw, C. Scott, and L. Souhami Single dose radiosurgical treatment of recurrent previously irradiated primary brain tumors and brain metastases: Final report of RTOG protocol 90-05 Int J Radiat Oncol Biol Phys 47 2000 291 298
3. M.A. Vogelbaum, L. Angelov, and S.Y. Lee Local control of brain metastases by stereotactic radiosurgery in relation to dose to the tumor margin J Neurosurg 104 2006 907 912
4. R.A. Patchell, P.A. Tibbs, and W.F. Regine Postoperative radiotherapy in the treatment of single metastases to the brain: A randomized trial JAMA 280 1998 1485 1489
5. M. Kocher, R. Soffietti, and U. Abacioglu Adjuvant whole-brain radiotherapy versus observation after radiosurgery or surgical resection of one to three cerebral metastases: Results of the EORTC 22952-26001 study J Clin Oncol 29 2011 134 141
6. C.A. Meyers, J.A. Smith, and A. Bezjak Neurocognitive function and progression in patients with brain metastases treated with whole-brain radiation and motexafin gadolinium: Results of a randomized phase III trial J Clin Oncol 22 2004 157 165
7. E. Chow, L. Davis, and L. Holden Prospective assessment of patient-rated symptoms following whole brain radiotherapy for brain metastases J Pain Symptom manage 30 2005 18 23
8. E.L. Chang, J.S. Wefel, and K.R. Hess Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irradiation: A randomised controlled trial Lancet Oncol 10 2009 1037 1044
9. L. Gaspar, C. Scott, and M. Rotman Recursive partitioning analysis (RPA) of prognostic factors in three Radiation Therapy Oncology Group (RTOG) brain metastases trials Int J Radiat Oncol Biol Phys 37 1997 745 751
10. P.W. Sperduto, B. Berkey, and L.E. Gaspar A new prognostic index and comparison to three other indices for patients with brain metastases: An analysis of 1,960 patients in the RTOG database Int J Radiat Oncol Biol Phys 70 2008 510 514
11. E.J. Hall, and A.J. Giaccia Radiobiology for the radiologist 6th ed. 2006 Lippincott Williams & Wilkins Philadelphia
12. H.T. Kim Cumulative incidence in competing risks data and competing risks regression analysis Clin Cancer Res 13 2007 559 565
13. E. Kaplan, and P. Meier Nonparametric estimation for incomplete observation J Am Stat Assoc 53 1958 457 481
14. D. Cox Statistical significance tests Br J Clin Pharmacol 14 1982 325 331
15. R.J. Yaes Some implications of the Linear Quadratic model for tumor control probability Int J Radiat Oncol Biol Phys 14 1988 147 157
16. D.W. Andrews, C.B. Scott, and P.W. Sperduto Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: Phase III results of the RTOG 9508 randomised trial Lancet 363 2004 1665 1672
17. T. Hasegawa, D. Kondziolka, and J.C. Flickinger Brain metastases treated with radiosurgery alone: An alternative to whole brain radiotherapy? Neurosurgery 52 2003 1318 1326 discussion 1326
18. H. Aoyama, H. Shirato, and M. Tago Stereotactic radiosurgery plus whole-brain radiation therapy vs stereotactic radiosurgery alone for treatment of brain metastases: A randomized controlled trial JAMA 295 2006 2483 2491
19. A. Sun, K. Bae, and E.M. Gore Phase III trial of prophylactic cranial irradiation compared with observation in patients with locally advanced non-small-cell lung cancer: Neurocognitive and quality-of-life analysis J Clin Oncol 29 2011 279 286
20. R.A. Patchell, P.A. Tibbs, and J.W. Walsh A randomized trial of surgery in the treatment of single metastases to the brain N Engl J Med 322 1990 494 500
21. L.J. Peters, H. Goepfert, and K.K. Ang Evaluation of the dose for postoperative radiation therapy of head and neck cancer: First report of a prospective randomized trial Int J Radiat Oncol Biol Phys 26 1993 3 11
22. D. Rades, A. Pluemer, and T. Veninga A boost in addition to whole-brain radiotherapy improves patient outcome after resection of 1 or 2 brain metastases in recursive partitioning analysis class 1 and 2 patients Cancer 110 2007 1551 1559
23. D. Roberge, K. Petrecca, and M. El Refae Whole-brain radiotherapy and tumor bed radiosurgery following resection of solitary brain metastases J Neurooncol 95 2009 95 99
24. Gore EM, Bae K, Wong SJ, et al. Phase III comparison of prophylactic cranial irradiation versus observation in patients with locally advanced non-small-cell lung cancer: Primary analysis of Radiation Therapy Oncology Group Study RTOG 0214. J Clin Oncol;29:272-278.