Fecal microbiota transplant to treat recurrent Clostridium difficile infections

Critical Care Nurse

Volumn 35, Issue 2, 2015, Pages 51-64

  Boyle, Miriam L ^a,b   Ruth Sahd, Lisa A ^a,c   Zhou, Zehao ^a  

^a YORK COLLEGE OF PENNSYLVANIA   (United States)

^b PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

^c LANCASTER GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; CASE REPORT; ENTEROCOLITIS, PSEUDOMEMBRANOUS; FECAL MICROBIOTA TRANSPLANTATION; FEMALE; FOLLOW UP; HOSPITAL EMERGENCY SERVICE; HUMAN; ISOLATION AND PURIFICATION; PEPTOCLOSTRIDIUM DIFFICILE; PROCEDURES; RECURRENT DISEASE; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

AGED; CLOSTRIDIUM DIFFICILE; EMERGENCY SERVICE, HOSPITAL; ENTEROCOLITIS, PSEUDOMEMBRANOUS; FECAL MICROBIOTA TRANSPLANTATION; FEMALE; FOLLOW-UP STUDIES; HUMANS; RECURRENCE; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

EID: 84930360074     PISSN: 02795442     EISSN: 19408250     Source Type: Journal    
DOI: 10.4037/ccn2015356     Document Type: Article

References (60)

1. Knight CL, Surawicz CM. Clostridium difficile infection. Med Clin North Am. 2013;97(4):523-536, ix.
2. Surawicz CM, Brandt LJ, Binion DG, et al. Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections. Am J Gastroenterol. 2013;108(4):478-498.
3. Kaseb HO, Novotne T. The changing face of Clostridium difficile in critical care. Nurs 2013 Crit Care. 2013;8(3):26-34.
4. Cohen SH, Gerding DN, Johnson S, et al; Society for Healthcare Epidemiology of America; Infectious Diseases Society of America. Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the Society for Health Epidemiology of America (SHEA) and the Infectious Diseases Society of America. Infect Control Hosp Epidemiol. 2010;31:431-455. doi:10:101086/651706.
5. Banning M. Ageing and C difficile infection-the immune and gastrointestinal impact. Gastrointest Nurs. 2011;9(4):42-47.
6. Centers for Disease Control and Prevention. CDC Vital Signs: stopping C difficile infections. http://www.cdc.gov/VitalSigns/Hai/StoppingCdifficile. Published March 2012. Accessed December 30, 2014.
7. Hessen MT. In the clinic: Clostridium difficile infection. Ann Intern Med. 2010; 153(7):ITC4-1-ITC4-15. doi:10.7326/0003-4819-153-7-201010050-01004.
8. Badger VO, Ledeboer NA, Graham MB, Edmiston CE. Clostridium difficile: epidemiology, pathogenesis, management, and prevention of a recalcitrant healthcare-associated pathogen. JPEN J Parenter Enteral Nutr. 2012; 36(6):645-662.
9. Simor AE. Diagnosis, management, and prevention of Clostridium difficile infection in long-term care facilities: a review. J Am Geriatr Soc. 2010; 58(8):1556-1564.
10. Gough E, Shaikh H, Manges AR. Systematic review of intestinal microbiota transplantation (fecal bacteriotherapy) for recurrent Clostridium difficile infection. Clin Infect Dis. 2011;53(10):994-1002.
11. Cober ED, Malani PN. Clostridium difficile infection in the "oldest" old: clinical outcomes in patients aged 80 and older. J Am Geriatr Soc. 2009; 57(4):659-662.
12. Department of Health. Clostridium difficile: guidance, data and analysis. https://www.gov.uk/government/collections/clostridium-difficile-guidance-data-and-analysis. Accessed February 2, 2015.
13. The Fecal Transplant Foundation. What is FMT? http://thefecaltransplant foundation.org/what-is-fecal-transplant/. Accessed December 30, 2014.
14. Agito MD, Atreja A, Rizk MK. Fecal microbiota transplantation for recurrent C difficile infection: ready for prime time? Cleve Clin J Med. 2014;80(2):101-108.
15. Myers F. Beyond mainstream: making the case for fecal bacteriotherapy. Nursing. 2011;41(12) 50-53.
16. Guo B, Harstall C, Louie T, Veldhuyzen van Zanten S, Dieleman LA. Systematic review: faecal transplantation for the treatment of Clostridium difficile-associated disease. Aliment Pharmacol Ther. 2012;35(8):865-875.
17. Patel NC, Griesbach CL, DiBaise JK, Orenstein R. Fecal microbiota transplant for recurrent Clostridium difficile infection: Mayo Clinic in Arizona experience. Mayo Clin Proc. 2012;88(8):799-805.
18. Lofland D, Josephat S, Partin S. Fecal transplant for recurrent Clostridium difficile infection. Clin Lab Sci. 2013;26(3):131-135.
19. Khoruts A, Dicksved J, Jansson JK, Sadowsky MJ. Changes in the composition of the human fecal microbiome after bacteriotherapy for recurrent Clostridium difficile-associated diarrhea. J Clin Gastroenterol. 2010; 44(5):354-360.
20. Shih C. The gut flora. J Lancaster Gen Hosp. 2013;8(4):114-117.
21. Khanna S, Tosh PK. A clinician's primer on the role of the microbiome in human health and disease. Mayo Clin Proc. 2014;89(1):107-114.
22. Suwantarat N, Bobak DA. Fecal bacteriotherapy for recurrent Clostridium difficile infection: what's old is new again? Curr Infect Dis Rep. 2013; 15(2):101-103.
23. Warny M, Pepin J, Fang A, et al. Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe. Lancet. 2005;366(9194):1079-1084.
24. Taggart H, Bergstrom L. An overview of the microbiome and the effects of antibiotics. J Nurse Pract. 2014;10(7):445-450.
25. National Institutes of Health. Human microbiome project. http://commonfund.nih.gov/hmp/index. Accessed February 2, 2015.
26. Shaw W. Increased urinary excretion of a 3-(3-hydroxyphenyl)-3-hydroxypropionic acid (HPHPA), an abnormal phenylalanine metabolite of Clostridia spp in the gastrointestinal tract, in urine samples from patients with autism and schizophrenia. Nutr Neurosci. 2010;13(3):135-143.
27. Kelly CR, Ihunnah C, Fischer M, et al. Fecal microbiota transplant for treatment of Clostridium difficile infection in immunocompromised patients. Am J Gastroenterol. 2014;109(7):1065-1071.
28. Li L, Somerset S. The clinical significance of the gut microbiota in cystic fibrosis and the potential for dietary therapies. Clin Nutr. 2014;33(4): 571-580.
29. Ridaura VK, Faith JJ, Rey FE, et al. Gut microbiota from twins discordant for obesity modulate metabolism in mice. Science. 2013; 341(6150):1241214.
30. Keske LA, Letizia M. Clostridium difficile infection: essential information for nurses. Medsurg Nurs. 2010;19(6):329-333.
31. Sebaihia M, Wren BW, Mullany P, et al. The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. Nature Genet. 2006;38(7):779-786.
32. Grossman S, Mager D. Clostridium difficile: implications for nursing. Medsurg Nurs. 2010;19(3):155-158.
33. Vonberg R. Infection control measures to limit the spread of Clostridium difficile. Clin Microb Infect. 2008;14(2):20-26.
34. McFarland LV. Renewed interest in a difficult disease: Clostridium difficile infections-epidemiology and current treatment strategies. Curr Opin Gastroenterol. 2009;25(1):24-35.
35. Gardner E, Meghani N, Mancuso P, Thomson A. Recognizing metronidazole resistant C difficile. Nurse Pract. 2011;36(11):8-11.
36. Brandt LJ, Reddy SS. Fecal microbiota transplant for recurrent Clostridium difficile infection. J Clin Gastroenterol. 2011;45(suppl):S159-S167.
37. Kelly CR, de Leon, L, Jasutkar N. Fecal microbiota transplantation for relapsing Clostridium difficile infection in 26 patients: methodology and results. J Clin Gastroenterol. 2012;46(2):145-149.
38. Brandt LJ, Aroniadis OC, Mellow M, et al. Long-term follow-up of colonoscopic fecal microbiota transplant for recurrent Clostridium difficile infection. Am J Gastroenterol. 2012;107(7):1079-1087.
39. Bakken J. Fecal bacteriotherapy for recurrent Clostridium difficile infection. Anaerobe. 2009;15(6):285-289.
40. Garborg K, Waagsbø B, Stallemo A, Matre J, Sundøy A. Results of faecal donor instillation therapy for recurrent Clostridium difficile-associated diarrhea. Scand J Infect Dis. 2010;42(11-12):857-861.
41. Pamer EG. Fecal microbiota transplantation: effectiveness, complexities, and lingering concerns. Mucosal Immunol. 2014;7:210-214.
42. Mitchell I, Shropshire K, Ruel J. Clostridium difficile infection and fecal bacteriotherapy. Gastroenterol Nurs. 2013:36(1):42-50.
43. Eiseman B, Silen W, Bascom GS, Kauvar AJ. Fecal enema as an adjunct in the treatment of pseudomembranous enterocolitis. Surgery. 1958;44(5): 854-859.
44. Schwan A, Sjölin S, Trottestam U, Aronsson B. Relapsing Clostridium difficile enterocolitis cured by rectal infusion of homologous faeces. Lancet. 1983;2(8354):845.
45. Louie T, Cannon K, O'grady H, Wu K, Ward L. Fecal microbiome transplantation (FMT) via oral fecal microbial capsules for recurrent Clostridium difficile infection (rCDI). Abstract 89. Presented at: IDWeek 2013; October 2-6, 2013; San Francisco, CA. https://idsa.confex.com/idsa/2013/webprogram/Paper41627.html. Accessed December 30, 2014.
46. Brandt L. Faecal microbiota transplant. Gastrointest Nurs. 2012;10(2):6-7.
47. Owens C, Broussard E, Surawicz C. Fecal microbiota transplantation and donor standardization. Trends Microbiol. 2013;21(9):443-445.
48. Hamilton MJ, Weingarden AR, Sadowsky MJ, Khoruts A. Standardized frozen preparation for transplantation of fecal microbiota for recurrent Clostridium difficile infection. Am J Gastroenterol. 2012;107(5):761-767.
49. Aas J, Gessert CE, Bakken JS. Recurrent Clostridium difficile colitis: a series involving 18 patients treated with donor stool administered via a nasogastric tube. Clin Infect Dis. 2003;36(5):580-585. 50, Silverman MS, Davis I, Pillai DR. Success of self-administered home fecal transplantation for chronic Clostridium difficile infections. Clin Gastroenterol Hepatol. 2010;8(5):471-473.
50. Silverman MS, Davis I, Pillai DR. Success of self-administered home fecal transplantation for chronic Clostridium difficile infections. Clin Gastroenterol Hepatol. 2010;8(5):471-473.
51. van Nood E, Vrieze A, Nieuwdorp M, et al. Duodenal infusion of feces for recurrent Clostridium difficile. N Engl J Med. 2013;368:407-415.
52. Mattila E, Uusitalo-Seppälä R, Wuorela M, et al. Fecal transplantation, through colonoscopy, is effective therapy for recurrent Clostridium difficile infection. Gastroenterology. 2012;142(3):490-496.
53. Avery L, Hasan M. Fecal bacteriotherapy for Clostridium difficile infections- its time has come. Clin Microbiol Newsl. 2013;35(15):119-124.
54. Orenstein R, Griesbach CL, DiBaise JK. Moving fecal microbiota transplantation into the mainstream. Nutr Clin Pract. 2013;28(5):589-598.
55. Bakken JS, Borody T, Brandt LJ, et al; Fecal Microbiota Transplantation Workgroup. Treating Clostridium difficile infections with fecal microbiota transplantation. Clin Gastroenterol Hepatol. 2011;9(12):1044-1049.
56. Schwartz M, Gluck M, Koon S. Novovirus gastroenteritis after fecal microbiota transplant for treatment of Clostridium difficile infections despite asymptomatic donors and lack of sick contacts. Am J Gastroenterol. 2013;108:1367.
57. Haugen N, Galura S. Ulrich & Canale's Nursing Care Planning Guides: Prioritization, Delegation, and Critical Thinking. 7th ed. St Louis, MO: Elsevier; 2013.
58. MacLeod-Glover N, Sadowski C. Efficacy of cleaning products for C difficile: environmental strategies to reduce the spread of Clostridium difficile-associated diarrhea in geriatric rehabilitation. Can Fam Physician. 2010;56(5):417-423.
59. Landers T, Abusalem S, Coty MB, Bingham J. Patient-centered hand hygiene: the next step in infection prevention. Am J Infect Control. 2012; 40(4)(suppl):S11-S17.
60. Johnson J. Setting up an isolation and treatment unit for C difficile. Nurs Times. 2008;104(25):30-31.