Loss of endothelial protein C receptors links coagulation and inflammation to parasite sequestration in cerebral malaria in African children

Blood

Volumn 122, Issue 5, 2013, Pages 842-851

  Moxon, Christopher A ^a,b,h   Wassmer, Samuel C ^c   Milner Jr , Danny A ^d   Chisala, Ngawina V ^a   Taylor, Terrie E ^a,e   Seydel, Karl B ^a,e   Molyneux, Malcolm E ^a   Faragher, Brian ^b   Esmon, Charles T ^f,g   Downey, Colin ^h   Toh, Cheng Hock ^h   Craig, Alister G ^b   Heyderman, Robert S ^a,b  

^a UNIVERSITY OF MALAWI   (Malawi)

^b LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e MICHIGAN STATE UNIVERSITY   (United States)

^f OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^g HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^h UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR; CD31 ANTIGEN; ENDOTHELIAL PROTEIN C RECEPTOR; FIBRIN; INTERCELLULAR ADHESION MOLECULE 1; THROMBOMODULIN; CELL SURFACE RECEPTOR; LEUKOCYTE ANTIGEN; PROCR PROTEIN, HUMAN; THBD PROTEIN, HUMAN;

AFRICA; ARTICLE; AUTOPSY; BLOOD CLOTTING DISORDER; BRAIN HEMORRHAGE; BRAIN MALARIA; CELL ADHESION; CEREBROSPINAL FLUID; CHILD; CONTROLLED STUDY; ERYTHROCYTE; EX VIVO STUDY; FEMALE; HUMAN; HUMAN TISSUE; INFANT; INFLAMMATION; MAJOR CLINICAL STUDY; MALARIA; MALE; MICROVASCULATURE; PHENOTYPE; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCHOOL CHILD; THROMBOSIS; BLOOD; BLOOD CLOTTING; BRAIN; CASE CONTROL STUDY; DOWN REGULATION; IMMUNOLOGY; MALAWI; METABOLISM; NEGRO; PARASITOLOGY; PATHOLOGY; PHYSIOLOGY; VASCULAR ENDOTHELIUM; VASCULARIZATION;

AFRICAN CONTINENTAL ANCESTRY GROUP; ANTIGENS, CD; BLOOD COAGULATION; BRAIN; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; DOWN-REGULATION; ENDOTHELIUM, VASCULAR; ERYTHROCYTES; FEMALE; HUMANS; INFANT; INFLAMMATION; MALARIA, CEREBRAL; MALAWI; MALE; RECEPTORS, CELL SURFACE; THROMBOMODULIN;

EID: 84885941107     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-03-490219     Document Type: Article

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