Small molecule inhibitors of HIVgp41 N-heptad repeat trimer formation

Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 14, 2015, Pages 2853-2859

  Allen, William J ^a   Yi, Hyun Ah ^b   Gochin, Miriam ^c,d   Jacobs, Amy ^b   Rizzo, Robert C ^a,e  

^a Stony Brook University   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

^c Touro University California   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e STONY BROOK UNIVERSITY   (United States)

Author keywords

DOCK; Docking; Footprint similarity; gp41; HIV; Virtual screening

Indexed keywords

GLYCOPROTEIN GP 41; HUMAN IMMUNODEFICIENCY VIRUS FUSION INHIBITOR; MOLECULAR LIBRARY;

ANTIVIRAL ACTIVITY; ARTICLE; CHEMICAL FUSION (CELL); CONTROLLED STUDY; DRUG DESIGN; DRUG IDENTIFICATION; DRUG INHIBITION; DRUG SCREENING; DRUG STRUCTURE; MOLECULAR DYNAMICS; NONHUMAN; ANTAGONISTS AND INHIBITORS; BINDING SITE; CELL LINE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; METABOLISM; MOLECULAR DOCKING; MOLECULAR LIBRARY; PHARMACOLOGY; PROTEIN MULTIMERIZATION; PROTEIN TERTIARY STRUCTURE; VIRUS ENTRY;

BINDING SITES; CELL LINE; CELL SURVIVAL; DRUG DESIGN; HIV ENVELOPE PROTEIN GP41; HIV FUSION INHIBITORS; HIV-1; HUMANS; MOLECULAR DOCKING SIMULATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; SMALL MOLECULE LIBRARIES; VIRUS INTERNALIZATION;

EID: 84930272167     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2015.04.067     Document Type: Article

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