Footprint-based identification of viral entry inhibitors targeting HIVgp41

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 8, 2012, Pages 3011-3016

  Holden, Patrick M ^a   Kaur, Harmeet ^b   Goyal, Rashi ^c   Gochin, Miriam ^b,d   Rizzo, Robert C ^a,e  

^a USA   (United States)

^b Touro University   (United States)

^c Stony Brook University   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e STONY BROOK UNIVERSITY   (United States)

Author keywords

DOCK; Docking; HIVgp41; Molecular footprints; Pose rescoring; Structure based drug design; Virtual screening

Indexed keywords

ANTIVIRUS AGENT; DOCKING PROTEIN; GLYCOPROTEIN GP 41;

ARTICLE; BINDING AFFINITY; CELL FUSION; CONTROLLED STUDY; CYTOTOXICITY; DRUG IDENTIFICATION; DRUG SCREENING; HUMAN IMMUNODEFICIENCY VIRUS; HYDROPHOBICITY; IC 50; NONHUMAN; PROTEIN FOOTPRINTING; VIRUS ENTRY;

COMPUTER SIMULATION; DRUG DESIGN; HIV ENVELOPE PROTEIN GP41; HIV FUSION INHIBITORS; MODELS, MOLECULAR; STRUCTURE-ACTIVITY RELATIONSHIP; VIRUS INTERNALIZATION;

EID: 84859437944     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.02.017     Document Type: Article

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