Lineage Tracing Using Cux2-Cre and Cux2-CreERT2 Mice

Neuron

Volumn 86, Issue 4, 2015, Pages 1091-1099

  Gil Sanz, Cristina ^a   Espinosa, Ana ^a   Fregoso, Santiago P ^b   Bluske, Krista K ^a   Cunningham, Christopher L ^a   Martinez Garay, Isabel ^c   Zeng, Hongkui ^d   Franco, Santos J ^b,e,f   Müller, Ulrich ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d ALLEN INSTITUTE FOR BRAIN SCIENCE   (United States)

^e Children's Hospital Colorado   (United States)

^f CHILDREN S HOSPITAL COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BREEDING; CELL FATE; CELL LINEAGE; CELL POPULATION; CONTROLLED STUDY; CUX2 CRE MICE; CUX2 CREERT2 MICE; EMBRYO; GENE EXPRESSION; GENE LOCUS; GENE MAPPING; GENETIC RECOMBINATION; IN SITU HYBRIDIZATION; INBRED MOUSE STRAIN; MACROGLIA; MOUSE; NEOCORTEX; NEOCORTICAL VENTRICULAR ZONE; NONHUMAN; PRIORITY JOURNAL; TRANSGENE; ANIMAL; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NERVE CELL; PHYSIOLOGY; TRANSGENIC MOUSE;

CUTL2 PROTEIN, MOUSE; HOMEODOMAIN PROTEIN; INTEGRASE;

ANIMALS; CELL LINEAGE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; INTEGRASES; MICE, TRANSGENIC; NEURONS; TRANSGENES;

EID: 84930260560     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2015.04.019     Document Type: Article

References (28)

1. Alcamo E.A., Chirivella L., Dautzenberg M., Dobreva G., Fariñas I., Grosschedl R., McConnell S.K. Satb2 regulates callosal projection neuron identity in the developing cerebral cortex. Neuron 2008, 57:364-377.
2. Arlotta P., Molyneaux B.J., Chen J., Inoue J., Kominami R., Macklis J.D. Neuronal subtype-specific genes that control corticospinal motor neuron development invivo. Neuron 2005, 45:207-221.
3. Belvindrah R., Graus-Porta D., Goebbels S., Nave K.-A., Müller U. Beta1 integrins in radial glia but not in migrating neurons are essential for the formation of cell layers in the cerebral cortex. J.Neurosci. 2007, 27:13854-13865.
4. Belvindrah R., Hankel S., Walker J., Patton B.L., Müller U. Beta1 integrins control the formation of cell chains in the adult rostral migratory stream. J.Neurosci. 2007, 27:2704-2717.
5. Britanova O., de Juan Romero C., Cheung A., Kwan K.Y., Schwark M., Gyorgy A., Vogel T., Akopov S., Mitkovski M., Agoston D., et al. Satb2 is a postmitotic determinant for upper-layer neuron specification in the neocortex. Neuron 2008, 57:378-392.
6. Cubelos B., Sebastián-Serrano A., Kim S., Moreno-Ortiz C., Redondo J.M., Walsh C.A., Nieto M. Cux-2 controls the proliferation of neuronal intermediate precursors of the cortical subventricular zone. Cereb. Cortex 2008, 18:1758-1770.
7. Eckler M.J., Nguyen T.D., McKenna W.L., Fastow B.L., Guo C., Rubenstein J.L.R., Chen B. Cux2-positive radial glial cells generate diverse subtypes of neocortical projection neurons and macroglia. Neuron 2015, 86:1100-1108. this issue.
8. Fame R.M., MacDonald J.L., Macklis J.D. Development, specification, and diversity of callosal projection neurons. Trends Neurosci. 2011, 34:41-50.
9. Franco S.J., Martinez-Garay I., Gil-Sanz C., Harkins-Perry S.R., Müller U. Reelin regulates cadherin function via Dab1/Rap1 to control neuronal migration and lamination in the neocortex. Neuron 2011, 69:482-497.
10. Franco S.J., Gil-Sanz C., Martinez-Garay I., Espinosa A., Harkins-Perry S.R., Ramos C., Müller U. Fate-restricted neural progenitors in the mammalian cerebral cortex. Science 2012, 337:746-749.
11. Gao P., Postiglione M.P., Krieger T.G., Hernandez L., Wang C., Han Z., Streicher C., Papusheva E., Insolera R., Chugh K., et al. Deterministic progenitor behavior and unitary production of neurons in the neocortex. Cell 2014, 159:775-788.
12. Ge W.-P., Miyawaki A., Gage F.H., Jan Y.-N., Jan L.Y. Local generation of glia is a major astrocyte source in postnatal cortex. Nature 2012, 484:376-380.
13. Gorski J.A., Talley T., Qiu M., Puelles L., Rubenstein J.L.R., Jones K.R. Cortical excitatory neurons and glia, but not GABAergic neurons, are produced in the Emx1-expressing lineage. J.Neurosci. 2002, 22:6309-6314.
14. Guenthner C.J., Miyamichi K., Yang H.H., Heller H.C., Luo L. Permanent genetic access to transiently active neurons via TRAP: targeted recombination in active populations. Neuron 2013, 78:773-784.
15. Guo C., Eckler M.J., McKenna W.L., McKinsey G.L., Rubenstein J.L.R., Chen B. Fezf2 expression identifies a multipotent progenitor for neocortical projection neurons, astrocytes, and oligodendrocytes. Neuron 2013, 80:1167-1174.
16. Hayashi S., McMahon A.P. Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse. Dev. Biol. 2002, 244:305-318.
17. Koop K.E., MacDonald L.M., Lobe C.G. Transcripts of Grg4, a murine groucho-related gene, are detected in adjacent tissues to other murine neurogenic gene homologues during embryonic development. Mech. Dev. 1996, 59:73-87.
18. Madisen L., Zwingman T.A., Sunkin S.M., Oh S.W., Zariwala H.A., Gu H., Ng L.L., Palmiter R.D., Hawrylycz M.J., Jones A.R., et al. A robust and high-throughput Cre reporting and characterization system for the whole mouse brain. Nat. Neurosci. 2010, 13:133-140.
19. Miyata T., Kawaguchi A., Saito K., Kawano M., Muto T., Ogawa M. Asymmetric production of surface-dividing and non-surface-dividing cortical progenitor cells. Development 2004, 131:3133-3145.
20. Molyneaux B.J., Arlotta P., Fame R.M., MacDonald J.L., MacQuarrie K.L., Macklis J.D. Novel subtype-specific genes identify distinct subpopulations of callosal projection neurons. J.Neurosci. 2009, 29:12343-12354.
21. Nieto M., Monuki E.S., Tang H., Imitola J., Haubst N., Khoury S.J., Cunningham J., Götz M., Walsh C.A. Expression of Cux-1 and Cux-2 in the subventricular zone and upper layers II-IV of the cerebral cortex. J.Comp. Neurol. 2004, 479:168-180.
22. Noctor S.C., Martínez-Cerdeño V., Ivic L., Kriegstein A.R. Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phases. Nat. Neurosci. 2004, 7:136-144.
23. Sohur U.S., Padmanabhan H.K., Kotchetkov I.S., Menezes J.R.L., Macklis J.D. Anatomic and molecular development of corticostriatal projection neurons in mice. Cereb. Cortex 2014, 24:293-303.
24. Vasistha N.A., García-Moreno F., Arora S., Cheung A.F.P., Arnold S.J., Robertson E.J., Molnár Z. Cortical and clonal contribution of Tbr2 expressing progenitors in the developing mouse brain. Cereb. Cortex 2014, Published online June 13, 2014. 10.1093/cercor/bhu125.
25. Wu S.-X., Goebbels S., Nakamura K., Nakamura K., Kometani K., Minato N., Kaneko T., Nave K.-A., Tamamaki N. Pyramidal neurons of upper cortical layers generated by NEX-positive progenitor cells in the subventricular zone. Proc. Natl. Acad. Sci. USA 2005, 102:17172-17177.
26. Yang G., Smibert C.A., Kaplan D.R., Miller F.D. An eIF4E1/4E-T complex determines the genesis of neurons from precursors by translationally repressing a proneurogenic transcription program. Neuron 2014, 84:723-739.
27. Zervas M., Millet S., Ahn S., Joyner A.L. Cell behaviors and genetic lineages of the mesencephalon and rhombomere 1. Neuron 2004, 43:345-357.
28. Zimmer C., Tiveron M.-C., Bodmer R., Cremer H. Dynamics of Cux2 expression suggests that an early pool of SVZ precursors is fated to become upper cortical layer neurons. Cereb. Cortex 2004, 14:1408-1420.