The c-Myc–LDHA axis positively regulates aerobic glycolysis and promotes tumor progression in pancreatic cancer

Medical Oncology

Volumn 32, Issue 7, 2015, Pages

  He, Tian Lin ^a   Zhang, Yi Jie ^a   Jiang, Hui ^a   Li, Xiao hui ^b   Zhu, Hai ^c   Zheng, Kai Lian ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b Department of Oncological Surgery Jiaozuo People s Hospital   (China)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

c Myc; LDHA; Tumor progression; Warburg effect

Indexed keywords

DEOXYGLUCOSE; LACTATE DEHYDROGENASE; LACTATE DEHYDROGENASE A; LACTIC ACID; MYC PROTEIN; UNCLASSIFIED DRUG; GLUCOSE; ISOENZYME; LACTATE DEHYDROGENASE 5;

ADULT; AEROBIC GLYCOLYSIS; ANAEROBIC GLYCOLYSIS; ARTICLE; CANCER GROWTH; CANCER PROGNOSIS; CANCER SIZE; CANCER STAGING; CELL MIGRATION; FEMALE; GENE OVEREXPRESSION; GENE SILENCING; GLUCOSE INTAKE; GLYCOLYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; METASTASIS; PANCREAS CANCER; PANCREATIC CANCER CELL LINE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; DISEASE COURSE; GENETICS; MIDDLE AGED; PANCREAS TUMOR; PATHOLOGY; TUMOR CELL LINE; UPREGULATION;

CELL LINE, TUMOR; DISEASE PROGRESSION; FEMALE; GLUCOSE; GLYCOLYSIS; HUMANS; ISOENZYMES; L-LACTATE DEHYDROGENASE; MALE; MIDDLE AGED; PANCREATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-MYC; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84930221860     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-015-0633-8     Document Type: Article

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