An extract of Artemisia dracunculus L. stimulates insulin secretion from β cells, activates AMPK and suppresses inflammation

Journal of Ethnopharmacology

Volumn 170, Issue , 2015, Pages 98-105

  Aggarwal, Sita ^a   Shailendra, Giri ^b,d   Ribnicky, David M ^c   Burk, David ^a   Karki, Namrata ^a   Qingxia Wang, M S ^a  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

^b MAYO CLINIC   (United States)

^c RUTGERS UNIVERSITY   (United States)

^d HENRY FORD HOSPITAL   (United States)

Author keywords

Botanical(s); Diabetes; Inflammation; Insulin secretion; Islets; Pancreatic beta ( ) cells

Indexed keywords

ADENYLATE KINASE; ARTEMISIA DRACUNCULUS EXTRACT; CYTOKINE; GLUCOSE; INDUCIBLE NITRIC OXIDE SYNTHASE; INSULIN; INTERLEUKIN 6; METFORMIN; NITRIC OXIDE; PLANT EXTRACT; PROTEIN KINASE B; UNCLASSIFIED DRUG; ANTIINFLAMMATORY AGENT; AUTACOID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PMI-5011;

ANIMAL CELL; ARTEMISIA DRACUNCULUS; ARTICLE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY ASSAY; DIABETES MELLITUS; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HERB; HUMAN; HUMAN CELL; INFLAMMATION; INSULIN RELEASE; MACROPHAGE; MEDICINAL PLANT; MOUSE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; DRUG EFFECTS; FEMALE; METABOLISM; PATHOLOGY; SECRETION (PROCESS);

ARTEMISIA DRACUNCULUS; ASTERACEAE;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTI-INFLAMMATORY AGENTS; FEMALE; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MACROPHAGES; MICE; MICE, INBRED C57BL; NITRIC OXIDE; PLANT EXTRACTS;

EID: 84930205854     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2015.05.003     Document Type: Article

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