Controlled delivery of a metabolic modulator promotes regulatory T cells and restrains autoimmunity

Journal of Controlled Release

Volumn 210, Issue , 2015, Pages 169-178

  Gammon, Joshua M ^a   Tostanoski, Lisa H ^a   Adapa, Arjun R ^a   Chiu, Yu Chieh ^a   Jewell, Christopher M ^a,b,c  

^a UNIVERSITY OF MARYLAND   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MARYLAND GREENEBAUM CANCER CENTER   (United States)

Author keywords

Autoimmunity; Biomaterial; Immunology; Immunotherapy; Metabolism; Nanoparticle; Tolerance; Vaccine

Indexed keywords

BIOMATERIALS; CELL ENGINEERING; CELLS; CYTOLOGY; CYTOTOXICITY; DRUG DOSAGE; FITS AND TOLERANCES; IMMUNE SYSTEM; IMMUNOLOGY; MAMMALS; METABOLISM; MODULATORS; MOLECULES; NANOPARTICLES; PHYSIOLOGY; T-CELLS; TOXICITY; VACCINES;

ADAPTIVE IMMUNE RESPONSE; AUTOIMMUNITY; CYTOKINE SECRETIONS; DENDRITIC CELLS (DCS); ENGINEERING MATERIALS; IMMUNOTHERAPY; PRO-INFLAMMATORY CYTOKINES; THERAPEUTIC BENEFITS;

CELL SIGNALING;

CHROMENE DERIVATIVE; IMMUNOMODULATING AGENT; N PHENYL 7 (HYDROXYIMINO)CYCLOPROPA[B]CHROMEN 1A CARBOXAMIDE; NANOPARTICLE; UNCLASSIFIED DRUG; BENZOPYRAN DERIVATIVE; CYTOKINE; DELAYED RELEASE FORMULATION; LACTIC ACID; METABOTROPIC RECEPTOR; N-PHENYL-7-(HYDROXYIMINO)CYCLOPROPA(B)CHROMEN-1A-CARBOXAMIDE; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ANIMAL CELL; ARTICLE; AUTOIMMUNITY; CELL ACTIVATION; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; FEMALE; IMMUNOTHERAPY; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; TH17 CELL; ADMINISTRATION AND DOSAGE; ANIMAL; ANTAGONISTS AND INHIBITORS; ANTIGEN PRESENTATION; C57BL MOUSE; CELL PROLIFERATION; CHEMISTRY; COCULTURE; CYTOLOGY; DELAYED RELEASE FORMULATION; DRUG EFFECTS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; IMMUNOLOGY; MULTIPLE SCLEROSIS; PATHOLOGY; SPLEEN; T LYMPHOCYTE; THERAPEUTIC USE; TRANSGENIC MOUSE;

ANIMALS; ANTIGEN PRESENTATION; AUTOIMMUNITY; BENZOPYRANS; CELL PROLIFERATION; COCULTURE TECHNIQUES; CYTOKINES; DELAYED-ACTION PREPARATIONS; DENDRITIC CELLS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; LACTIC ACID; MICE, INBRED C57BL; MICE, TRANSGENIC; MULTIPLE SCLEROSIS; NANOPARTICLES; POLYGLYCOLIC ACID; RECEPTORS, METABOTROPIC GLUTAMATE; SPLEEN; T-LYMPHOCYTES;

EID: 84930202695     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.05.277     Document Type: Article

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