The effect of cognitive-motor dual-task training on cognitive function and plasma amyloid β peptide 42/40 ratio in healthy elderly persons: A randomized controlled trial

BMC Geriatrics

Volumn 15, Issue 1, 2015, Pages

  Yokoyama, Hisayo ^a   Okazaki, Kazunobu ^a   Imai, Daiki ^a   Yamashina, Yoshihiro ^a   Takeda, Ryosuke ^a   Naghavi, Nooshin ^a   Ota, Akemi ^a   Hirasawa, Yoshikazu ^a   Miyagawa, Toshiaki ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Amyloid peptide; Attention; Executive function; Exercise

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (40-42); PEPTIDE FRAGMENT;

AGED; ATTENTION; BLOOD; COGNITION; CONTROLLED STUDY; EXECUTIVE FUNCTION; EXERCISE; FEMALE; HUMAN; MALE; PHYSIOLOGY; PSYCHOLOGY; PSYCHOMOTOR PERFORMANCE; RANDOMIZED CONTROLLED TRIAL; RECALL; TRAIL MAKING TEST;

AGED; AMYLOID BETA-PEPTIDES; ATTENTION; COGNITION; EXECUTIVE FUNCTION; EXERCISE; FEMALE; HUMANS; MALE; MENTAL RECALL; PEPTIDE FRAGMENTS; PSYCHOMOTOR PERFORMANCE; TRAIL MAKING TEST;

EID: 84930199266     PISSN: None     EISSN: 14712318     Source Type: Journal    
DOI: 10.1186/s12877-015-0058-4     Document Type: Article

References (32)

1. Tinetti ME, Kumar C. The patient who falls: "It's always a trade-off". J American Med Assoc. 2010;303(3):258-66.
2. Lundin-Olsson L, Nyberg L, Gustafson Y. "Stops walking when talking" as a predictor of falls in elderly people. Lancet. 1997;349(9052):617.
3. Yaffe K, Barnes D, Nevitt M, Lui LY, Covinsky K. A prospective study of physical activity and cognitive decline in elderly women: women who walk. Arch Intern Med. 2001;161(14):1703-8.
4. Etgen T, Sander D, Huntgeburth U, Poppert H, Forstl H, Bickel H. Physical activity and incident cognitive impairment in elderly persons: the INVADE study. Arch Intern Med. 2010;170(2):186-93.
5. Lautenschlager NT, Cox KL, Flicker L, Foster JK, van Bockxmeer FM, Xiao J, Greenop KR, Almeida OP. Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease: a randomized trial. JAMA. 2008;300(9):1027-37.
6. Kemoun G, Thibaud M, Roumagne N, Carette P, Albinet C, Toussaint L, Paccalin M, Dugue B. Effects of a physical training programme on cognitive function and walking efficiency in elderly persons with dementia. Dement Geriatr Cogn Disord. 2010;29(2):109-14.
7. Jensen M, Schroder J, Blomberg M, Engvall B, Pantel J, Ida N, Basun H, Wahlund LO, Werle E, Jauss M, et al. Cerebrospinal fluid A beta42 is increased early in sporadic Alzheimer's disease and declines with disease progression. Ann Neurol. 1999;45(4):504-11.
8. Gravina SA, Ho L, Eckman CB, Long KE, Otvos Jr L, Younkin LH, Suzuki N, Younkin SG. Amyloid beta protein (A beta) in Alzheimer's disease brain. Biochemical and immunocytochemical analysis with antibodies specific for forms ending at A beta 40 or A beta 42(43). J Biol Chem. 1995;270(13):7013-6.
9. Graff-Radford NR, Crook JE, Lucas J, Boeve BF, Knopman DS, Ivnik RJ, Smith GE, Younkin LH, Petersen RC, Younkin SG. Association of low plasma Abeta42/Abeta40 ratios with increased imminent risk for mild cognitive impairment and Alzheimer disease. Arch Neurol. 2007;64(3):354-62.
10. Malito E, Hulse RE, Tang WJ. Amyloid beta-degrading cryptidases: insulin degrading enzyme, presequence peptidase, and neprilysin. Cellular Molecular Life Sci. 2008;65(16):2574-85.
11. Teng EL, Chui HC. The Modified Mini-Mental State (3MS) examination. J Clin Psychiatry. 1987;48(8):314-8.
12. Yokoyama H, Emoto M, Fujiwara S, Motoyama K, Morioka T, Komatsu M, Tahara H, Shoji T, Okuno Y, Nishizawa Y. Quantitative insulin sensitivity check index and the reciprocal index of homeostasis model assessment in normal range weight and moderately obese type 2 diabetic patients. Diabetes Care. 2003;26(8):2426-32.
13. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28(7):412-9.
14. Carvalho A, Rea IM, Parimon T, Cusack BJ. Physical activity and cognitive function in individuals over 60 years of age: a systematic review. Clin Interv Aging. 2014;9:661-82.
15. Erickson KI, Voss MW, Prakash RS, Basak C, Szabo A, Chaddock L, Kim JS, Heo S, Alves H, White SM, et al. Exercise training increases size of hippocampus and improves memory. Proc Natl Acad Sci U S A. 2011;108(7):3017-22.
16. Ruitenberg A, den Heijer T, Bakker SL, van Swieten JC, Koudstaal PJ, Hofman A, Breteler MM. Cerebral hypoperfusion and clinical onset of dementia: the Rotterdam Study. Ann Neurol. 2005;57(6):789-94.
17. Rhyu IJ, Bytheway JA, Kohler SJ, Lange H, Lee KJ, Boklewski J, McCormick K, Williams NI, Stanton GB, Greenough WT, et al. Effects of aerobic exercise training on cognitive function and cortical vascularity in monkeys. Neuroscience. 2010;167(4):1239-48.
18. Radak Z, Chung HY, Goto S. Exercise and hormesis: oxidative stress-related adaptation for successful aging. Biogerontology. 2005;6(1):71-5.
19. Stranahan AM, Zhou Y, Martin B, Maudsley S. Pharmacomimetics of exercise: novel approaches for hippocampally-targeted neuroprotective agents. Curr Med Chem. 2009;16(35):4668-78.
20. Voss MW, Erickson KI, Prakash RS, Chaddock L, Malkowski E, Alves H, Kim JS, Morris KS, White SM, Wojcicki TR, et al. Functional connectivity: a source of variance in the association between cardiorespiratory fitness and cognition? Neuropsychologia. 2010;48(5):1394-406.
21. Hawkins HL, Kramer AF, Capaldi D. Aging, exercise, and attention. Psychol Aging. 1992;7(4):643-53.
22. Smith PJ, Blumenthal JA, Hoffman BM, Cooper H, Strauman TA, Welsh-Bohmer K, Browndyke JN, Sherwood A. Aerobic exercise and neurocognitive performance: a meta-analytic review of randomized controlled trials. Psychosom Med. 2010;72(3):239-52.
23. Cooper C, Li R, Lyketsos C, Livingston G. Treatment for mild cognitive impairment: systematic review. British J Psychiatry. 2013;203(3):255-64.
24. Broadbent NJ, Squire LR, Clark RE. Spatial memory, recognition memory, and the hippocampus. Proc Natl Acad Sci U S A. 2004;101(40):14515-20.
25. Rosano C, Venkatraman VK, Guralnik J, Newman AB, Glynn NW, Launer L, Taylor CA, Williamson J, Studenski S, Pahor M, et al. Psychomotor speed and functional brain MRI 2 years after completing a physical activity treatment. J Gerontol A Biol Sci Med Sci. 2010;65(6):639-47.
26. de la Monte SM. Insulin resistance and Alzheimer's disease. BMB Rep. 2009;42(8):475-81.
27. Karczewska-Kupczewska M, Lelental N, Adamska A, Nikolajuk A, Kowalska I, Gorska M, Zimmermann R, Kornhuber J, Straczkowski M, Lewczuk P. The influence of insulin infusion on the metabolism of amyloid beta peptides in plasma. J Alzheimer's Assoc. 2013;9(4):400-5.
28. Baker LD, Frank LL, Foster-Schubert K, Green PS, Wilkinson CW, McTiernan A, Cholerton BA, Plymate SR, Fishel MA, Watson GS, et al. Aerobic exercise improves cognition for older adults with glucose intolerance, a risk factor for Alzheimer's disease. J Alzheimer's Dis. 2010;22(2):569-79.
29. Hamel FG, Upward JL, Bennett RG. In vitro inhibition of insulin-degrading enzyme by long-chain fatty acids and their coenzyme A thioesters. Endocrinology. 2003;144(6):2404-8.
30. Adlard PA, Perreau VM, Pop V, Cotman CW. Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer's disease. J Neurosci. 2005;25(17):4217-21.
31. Moritani T, de Vries HA. Potential for gross muscle hypertrophy in older men. J Gerontol. 1980;35(5):672-82.
32. Yoshii Y, Tominaga D, Sugimoto K, Tsuchida Y, Hyodo A, Yonaha H, Kushi S. Cognitive function of patients with brain tumor in pre- and postoperative stage. Surg Neurol. 2008;69(1):51-61. discussion 61.