Riboflavin in development and cell fate

Subcellular Biochemistry

Volumn 56, Issue , 2014, Pages 229-245

  Powers, Hilary J ^a   Corfe, B M ^a   Nakano, E ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Cell cycle; Cell fate; Gene expression; Riboflavin

Indexed keywords

EID: 84930197313     PISSN: 03060225     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Article

References (59)

1. Adiga PR, Murty CV (1983) Vitamin carrier proteins during embryogenic development in birds and mammals. Ciba Found Symp 98:111–136
2. Alisi A, Leoni S, Lacentani A, Dervirgillis LC (2003) Retinoic acid modulates the cell cycle in rat hepatocytes and HepG2 cells by regulating cyclin-CDK activities. Liver Int 23:179–186
3. Antozzi C, Garavaglia B, Mora M, Rimoldi M, Morandin L, Ursino E, DiDonato S (1994) Late-onset riboflavin-responsive myopathy with combined multiple acylCoA dehydrogenase and respiratory chain deficiency. Neurology 44:2153–2158
4. Bates CJ, Prentice AM, Paul AA, Prentice A, Sutcliffe BA, Whitehead RG (1982) Riboflavin status in infants born in rural Gambia and the effect of a weaning food supplement. Trans Roy Soc Trop Med 76:253–258
5. Bates CJ, Evans PH, Dardenne M, Prentice AM, Lunn PG, Northrop-Clewes CA, Hoare S, Cole TJ, Horan SJ, Longman SC (1993) A trial of zinc supplementation in young rural Gambian children. Brit J Nutr 69 243–255
6. Bohnsack BL, Hirschi KK (2004) Nutrient regulation of cell cycle progression. Ann Rev Nutr 24:433–453
7. Brady PS, Hoppel CL (1985) Hepatic peroxisomal and mitochondrial fatty acid oxidation in the riboflavin-deficient rat. Biochem J 299:717–721
8. Camporeale G, Zempleni J (2003) Oxidative folding of interleukin-2 is impaired in flavin-deficient Jurkat cells, causing intracellular accumulation of interleukin-2 and increased expression of stress response genes. J Nutr 133:668–672
9. Capo-chichi CD, Gueant JL, Feillet F, Namour F, Vidaillhet M (2000) Analysis of riboflavin and riboflavin cofactor levels in plasma by high performance liquid chromatography. J Chromatogr B Biomed Sci Appl 739(1):219–224
10. Chalmers RA, Bain MD, Zschocke J (2006) Riboflavin-responsive glutaryl dehydrogenase deficiency. Mol Genet Med 88:29–37
11. Chen TH, Chang TC, Kang JO, Choudhary, B, Makita, T, Tran C.M., Burch JB, Eid H, Sucor HM (2002) Epicardial induction of fetal cardiomyocyte proliferation via a retinoic acid-inducible trophic factor. Dev Biol 250:198–207
12. D’Souza VM, Foraker AB, Free RB, Ray. A., Shapiro PS, Swaan PW (2006) cAMP-coupled riboflavin trafficking in placental trophoblasts: A dynamic and ordered process. Biochem 45:6095–6104
13. Duerden JM, Bates CJ (1985) Effect of riboflavin deficiency on lipid metabolism of liver and brown adipose tissue of suckling rat pups. Brit J Nutr 53:107–115
14. Faron G, Drouin R, Pedneault L, Poulin LD, Laframboise R, Garrido-Russo M, Fraser WD (2001) Recurrent cleft lip and palate in siblings of a patient with malabsorption syndrome, probably caused by hypovitaminosis A associated with folic acid and vitamin (B2) deficiencies. Teratology 63:161–163
15. Fass S, Rivlin RS (1969) Regulation of riboflavin-metabolising enzymes in riboflavin deficiency. Amer J Physiol 217:988–991
16. Gianazza E, Vergani L, Wait R, Brizio C, Brambilla D, Begum S, Giancaspero TA, Conserva F, Eberini I, Bufano D, Angelini C, Pegoraro E, Tramontano A, Barile M (2006) Coordinated and reversible reduction of enzymes involved in terminal oxidative metabolism in skeletal muscle mitochondria from a riboflavin-responsive, multiple acyl CoA dehydrogenase deficiency patient. Electrophoresis 27:1182–1198
17. Goodman SI (1981) Organic aciduria in the riboflavin-deficient rat. Am J Clin Nutr 34:2434–2437
18. Harpey JP, Charpentier C, Goodman SI, Darbois Y, Lefebvre G, Sebbah J (1983) Multiple acyl CoA dehydrogenase deficiency occurring in pregnancy and caused by a defect in riboflavin metabolism in the mother. Study of a kindred with seven deaths in infancy: value of riboflavin therapy in preventing this syndrome. J Pediatr 103:394–398
19. Hoppel CL, Tandler B (1975) Riboflavin and mouse hepatic structure and function. Mitochondrial oxidative metabolism in severe deficiency states. J Nutr 105:562–570
20. Horvath C, Szony L, Mold K (1976) Preventive effect of riboflavin and ATP on the teratogenic effects of the phenathiozine derivative T-82. Teratology 14:167–170
21. Huang SN, Swaan PW (2000) Involvement of a receptor-mediated component in cellular translocation of riboflavin J Pharmacol Exp Ther 194:117–125
22. Huang SN, Phelps MA, Swaan PW (2003) Involvement of endocytic organelles in the subcellular trafficking and localisation of riboflavin. J Pharmacol Exp Ther 306:681–687
23. Hustad S, Ueland PM, Vollset SE, Zhang Y, Bjorke-Monsen AL, Schneede J (2000) Riboflavin as a determinant of plasma total homocysteine: Effect modification by the methylene tetrahydrofolate reductase C677T polymorphism. Clin Chem 46:1065–1071
24. Hustad S, McKinley MC, McNulty H, Schneede J, Strain JJ, Scott JM, Ueland PM (2002) Riboflavin, flavin mononucleotide, and flavin adenine dinucleotide in human plasma and erythrocyes at baseline and after low-dose riboflavin supplementation. Clin Chem 48:1571–1577
25. Johnson DG, Walker, CL (1999) Cyclins and cell cycle checkpoints. Ann Rev Pharmacol Toxicol 39:295–312
26. Juriloff DM, Roberts CW (1975) Genetics of cleft palate in chickens and the relationship between the occurrence of the trait and maternal riboflavin deficiency. Poult Sci 54:334–346
27. Kosaka C, Sasaguri T, Komiyama Y, Takahashi H (2001) All-trans retinoic acid inhibits vascular smooth muscle cell proliferation targeting multiple genes for cyclins and cyclin-dependent kinases. Hypertens Res 24:579–588
28. Manthey KC, Chew YC, Zempleni J (2005) Riboflavin deficiency impairs oxidative folding and secretion of apolipoprotein B-100 in HepG2 cells, triggering stress-response systems. J Nutr 135:978–982
29. Manthey KC, Rodriguez-Melendez R, Hoi JT, Zempleni J (2006) Riboflavin deficiency causes DNA damage in HepG2 cells, triggering arrest in G1 phase of the cell cycle. J Nutr Biochem. 17:250–256
30. Marshall KR, Gong M, Wodke L, Lamb JH, Jones DJL., Farmer PB, Scrutton NS, Munro AW (2005) The human apoptosis-inducing protein AMID is an oxidoreductase with a modified flavin cofactor and DNA binding activity. J Biol Chem 280:30735–30740
31. Mason CW, D’Souza VM, Bareford LM, Phelps MA, Ray A, Swaan PW (2006) Recognition, co-internalisation, and recycling of an avian riboflavin carrier protein in human placental trophoblasts. J Pharmacol Exp Ther 317:465–472
32. Miura R (2001) Versatility and specificity in flavoproteins: Control mechanisms of flavin reactivity, vol 1. The Chemical Record The Japan Chemical Journal Forum and John Wiley & Sons Inc., pp 83–94
33. Moat SJ, Ashfield-Watt PAL., Powers HJ, Newcombe RG, McDowell IFW (2003) Effect of riboflavin status on the homocysteine-lowering effect of folate in relation to the MTHFR (C677T) genotype. Clin Chem 49:295–302
34. Nakano E, Mushtaq S, Heath PR, Lee ES, Bury JP, Riley SA, Powers HJ, Corfe BM (2011) Riboflavin depletion impairs cell proliferation in adult human duodenum: identification of potential effectors. Dig Dis Sci Apr;56(4):1007–1019
35. Natraj U, George S, Kadam J (1988) Isolation and characterisation of human riboflavin carrier protein and the estimation of its levels during human pregnancy. Reprod Immunol 13:1–16
36. Nelson MM, Baird CDC, Wright V, Evans HM (1956) Multiple congenital abnormalities in the rat resulting from riboflavin deficiency induced by the antimetabolite galactoflavin. J Nutr 58:125–134
37. Noback CR, Kupperman HS (1944) Anomalous offspring and growth of Wistar rats maintained on a deficient diet. Proc Exp Biol Med 57:183–185
38. Olpin SE, Bates CJ (1982) Lipid metabolism in riboflavin-deficient rats 2. Mitochondrial fatty acid oxidation and the microsomal desaturation pathway. Br J Nutr 47:589–596
39. Pahl HL (1999) Signal transduction from the endoplasmic reticulum to the cell nucleus. Physiol Rev 79:683–700
40. Patterson BE, Bates CJ (1989) Riboflavin deficiency, metabolic rate and brown adipose tissue function in sucking and weanling rats. Br J Nutr 61:475–483
41. Patterson BE, Bates CJ, Halliday D, Lucas A (1989) 1-(13)C-octanoate metabolism, energy expenditure and vitamin B2 supplement in premature infants. Acta Paediatr Scand 78:780–781
42. Powers HJ, Hill MH, Mushtaq S, Dainty JR, Majsak-Newman G, Williams EA (2011) Correcting a marginal riboflavin deficiency improves hematologic status in young women in the United Kingdom (RIBOFEM). Am J Clin Nutr Jun;93(6):1274–1284
43. Prasad PD (1992) Isolation and characterisation of riboflavin carrier protein from human amniotic fluid. Biochem Int 2:385–395
44. Prentice AM, Bates CJ (1981) Biochemical evaluation of the erythrocyte glutathione reductase (EC 1.6.4.2) test for riboflavin status. Br J Nutr 45:37–52
45. Rao J, Seshagiri PB, Shetty G, Ramesh G, Adiga PR (2000) Active immunization against riboflavin carrier protein results in peri-implantation embryonic loss leading to pregnancy termination in rats: use of aternative adjuvants. Indian J Exp Biol 38:863–872
46. Ross NS, Hansen TP (1992) Riboflavin deficiency is associated with selective preservation of critical flavoenzyme-dependent metabolic pathways. Biofactors 3:185–190
47. Said HM, Orti A, Ma TY, McCloud E (1998) Riboflavin uptake bythe human-derived liver cells HepG2: mechanism and regulation. J Cell Physiol 176:588–594
48. Sidrauski C, Brickner JH, Walter P (2002) The unfolded protein response. In: Dalbey RE, von Heijne RE (eds) Protein targeting, transport and translocation. Academic, San Diego, CA, pp 151–179
49. Spinella MJ, Freemantle SJ, Sekula D, Chang JH, Christie AJ, Dnitrovsky E (1999) Retinoic acid promotes ubiquitination and proteolysis of cycle D1 during induced tumour differentiation. J Biol Chem 274:22013–22018
50. Stuckmann I, Evans S, Lassar AB (2003) Erythropoietin and retinoic acid, secreted from the epicardium, are required for cardiac myocyte proliferation. Dev Biol 255:334–349
51. Swami S, Raghavachari N, Muller UR, Bao YP, Fieldman D (2003) Vitamin D growth inhibition of breast cancer cells; gene expression patterns assessed by cDNA microarray. Breast Canc Res Treat 80:49–62
52. Tu BP, Ho-Schlyer SC, Travers KL, Weissman JS (2000) Biochemical basis of oxidative protein folding in the endoplasmic reticulum. Science 290:1571–1574
53. Visweswariah SS, Adiga PR (1987) Isolation of riboflavin carrier proteins from pregnant human and umbilical cord serum: Similarities with chicken egg riboflavin carrier protein. Biosci Rep 7:563–571
54. Werner R, Manthey KC, Griffin JB, Zempleni J (2005) HepG2 cells develop signs of riboflavin deficiency within 4 days of culture in riboflavin-deficient medium. J Nutr Biochem Oct;16(10):617–624
55. Williams EA, Rumsey RD, Powers HJ (1996a) An investigation into the reversibility of the morphological and cytokinetic changes seen in the small intestine of the riboflavin-deficient rat. Gut 39:220–225
56. Williams EA, Rumsey RD, Powers HJ (1996b) Cytokinetic and structural responses of the rat small intestine to riboflavin depletion. Brit J Nutr 75:315–324
57. Yates CA, Evans GS, Pearson T, Powers HJ (2003) Absence of luminal riboflavin disturbs early postnatal development of the gastrointestinal tract. Dig Dis Sci 48:1159–1164
58. Yates CA, Evans GS, Powers HJ (2001) Riboflavin deficiency: Early effects on post-weaning development of the duodenum in rats. Brit J Nutr 86:593–599
59. Zaman Z, Verwilghen RL (1975) Effect of riboflavin deficiency on oxidative phosphorylation, flavin enzymes and coenzymes in rat liver. Biochem Biophys Res Commun 67:1192–1198