Neuroprotective effects of safranal in a rat model of traumatic injury to the spinal cord by anti-apoptotic, anti-inflammatory and edema-attenuating

Tissue and Cell

Volumn 47, Issue 3, 2015, Pages 291-300

  Zhang, Chen ^a   Ma, Jun ^a   Fan, Lihong ^a   Zou, Yulong ^a   Dang, Xiaoqian ^a   Wang, Kunzheng ^a   Song, Jinhui ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

Neuronal protection; Rat; Safranal; Spinal cord injury; Traditional Chinese medicine

Indexed keywords

AQUAPORIN 4; INTERLEUKIN 10; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE P38; NATURAL PRODUCT; PROTEIN BAX; SAFRANAL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CYCLOHEXENE DERIVATIVE; IL10 PROTEIN, HUMAN; NEUROPROTECTIVE AGENT; TERPENE; TNF PROTEIN, HUMAN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIAPOPTOSIS ACTIVITY; ANTIEDEMA ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BASSO BEATTIE AND BRESNAHAN LOCOMOTOR RATING SCALE; BAX GENE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RESPONSE; DOWN REGULATION; DRUG ACTIVITY; DRUG DOSE COMPARISON; ELECTRON MICROSCOPY; GENE EXPRESSION REGULATION; HISTOPATHOLOGY; IMMUNOREACTIVITY; MALE; NEUROPROTECTION; NONHUMAN; PROTEIN EXPRESSION; PROTO ONCOGENE; RAT; RATING SCALE; SPINAL CORD INJURY; TUNEL ASSAY; UPREGULATION; ANIMAL; APOPTOSIS; BIOSYNTHESIS; DISEASE MODEL; DRUG EFFECTS; EDEMA; HUMAN; INFLAMMATION; NERVE CELL; PATHOLOGY; SPINAL CORD INJURIES;

RATTUS;

ANIMALS; APOPTOSIS; CYCLOHEXENES; DISEASE MODELS, ANIMAL; EDEMA; HUMANS; INFLAMMATION; INTERLEUKIN-10; MALE; NEURONS; NEUROPROTECTIVE AGENTS; RATS; SPINAL CORD INJURIES; TERPENES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84930091023     PISSN: 00408166     EISSN: 15323072     Source Type: Journal    
DOI: 10.1016/j.tice.2015.03.007     Document Type: Article

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