LC-MS/MS based assay and reference intervals in children and adolescents for oxysterols elevated in Niemann-Pick diseases

Clinical Biochemistry

Volumn 48, Issue 9, 2015, Pages 596-602

  Klinke, Glynis ^a,b   Rohrbach, Marianne ^a   Giugliani, Roberto ^c,d   Burda, Patricie ^a   Baumgartner, Matthias R ^a,b   Tran, Christel ^e   Gautschi, Matthias ^f,g   Mathis, Déborah ^a   Hersberger, Martin ^a,b  

^a UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

^d FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^e LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^f UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^g UNIVERSITY OF BERN   (Switzerland)

Author keywords

Liquid Chromatography Tandem Mass Spectrometry (LC MS MS); Niemann Pick; Oxysterols; Reference intervals; Steglich esterification

Indexed keywords

7 OXOCHOLESTEROL; CHOLESTANE 3 BETA,5 ALPHA,6 BETA TRIOL; OXYSTEROL; UNCLASSIFIED DRUG; 7-KETOCHOLESTEROL; BIOLOGICAL MARKER; CHOLESTANOL; CHOLESTEROL DERIVATIVE;

ADOLESCENT; ADULT; ARTICLE; CHILD; CHOLESTEROL ESTERIFICATION; CONTROLLED STUDY; DISEASE MARKER; HUMAN; INFANT; LIMIT OF DETECTION; LIQUID CHROMATOGRAPHY; MAJOR CLINICAL STUDY; MEASUREMENT ACCURACY; NEWBORN; NIEMANN PICK DISEASE; PRIORITY JOURNAL; REFERENCE VALUE; SENSITIVITY ANALYSIS; STEGLICH ESTERIFICATION; TANDEM MASS SPECTROMETRY; BLOOD; FEMALE; MALE; NIEMANN-PICK DISEASES; PRESCHOOL CHILD; PROCEDURES;

ADOLESCENT; BIOMARKERS; CHILD; CHILD, PRESCHOOL; CHOLESTANOLS; CHROMATOGRAPHY, LIQUID; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; KETOCHOLESTEROLS; LIMIT OF DETECTION; MALE; NIEMANN-PICK DISEASES; REFERENCE VALUES; TANDEM MASS SPECTROMETRY;

EID: 84929962069     PISSN: 00099120     EISSN: 18732933     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2015.03.007     Document Type: Article

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