Stimulation of osteogenesis and angiogenesis of hBMSCs by delivering Si ions and functional drug from mesoporous silica nanospheres

Acta Biomaterialia

Volumn 21, Issue , 2015, Pages 178-189

  Shi, Mengchao ^a   Zhou, Yinghong ^b   Shao, Jin ^b   Chen, Zetao ^b   Song, Botao ^a   Chang, Jiang ^a   Wu, Chengtie ^a   Xiao, Yin ^b  

^a SHANGHAI INSTITUTE OF CERAMICS   (China)

^b QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

Author keywords

Angiogenesis; Bone regeneration; Mesoporous silica nanospheres; Multifunction; Osteogenesis

Indexed keywords

BONE; CELL CULTURE; CONTROLLED DRUG DELIVERY; DEFECTS; GENE EXPRESSION; MESOPOROUS MATERIALS; NANOSPHERES; PROTEINS; SCAFFOLDS (BIOLOGY); SILICA; SILICON; STEM CELLS; TARGETED DRUG DELIVERY; TISSUE REGENERATION;

ANGIOGENESIS; BONE REGENERATION; HUMAN BONE MARROW STROMAL CELLS; MESOPORE; MESOPOROUS SILICAS; MESOPOROUS SILICUM NANOSPHERE; MULTI-FUNCTIONS; OSTEOGENESIS; SILICA NANOSPHERES; SILICON ION;

IONS;

ALKALINE PHOSPHATASE; DIMETHYLOXALOYLGLYCINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR PROLYL HYDROXYLASE INHIBITOR; SILICA NANOPARTICLE; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG; VASCULOTROPIN; NANOMATERIAL; SILICON DIOXIDE;

ANGIOGENESIS; ARTICLE; BONE DEVELOPMENT; BONE MARROW STROMA CELL; BONE REGENERATION; CELL DIFFERENTIATION; CELL VIABILITY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG RELEASE; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SURFACE AREA; X RAY DIFFRACTION; ZETA POTENTIAL; CHEMISTRY; CYTOLOGY; ELECTRON MICROSCOPY; MESENCHYMAL STROMA CELL;

HUMANS; MESENCHYMAL STROMAL CELLS; MICROSCOPY, ELECTRON; NANOSTRUCTURES; NEOVASCULARIZATION, PHYSIOLOGIC; OSTEOGENESIS; SILICON DIOXIDE;

EID: 84929961950     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2015.04.019     Document Type: Article

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