Prolyl hydroxylase inhibition during hyperoxia prevents oxygen-induced retinopathy

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 50, 2008, Pages 19898-19903

  Sears, Jonathan E ^a   Hoppe, George ^a   Ebrahem, Quteba ^a   Anand Apte, Bela ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Dimethyloxalylglycine; Erythropoeitin; Hypoxia inducible factor; Retinopathy of prematurity; Vascular endothelial growth factor

Indexed keywords

DIMETHYLOXALYLGLYCINE; ERYTHROPOIETIN; GLUTARIC ACID DERIVATIVE; HYPOXIA INDUCIBLE FACTOR 1; OXYGEN; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; UNCLASSIFIED DRUG; VASCULOTROPIN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; DICARBOXYLIC AMINO ACID; ENDOTHELIAL PAS DOMAIN CONTAINING PROTEIN 1; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; ENZYME INHIBITOR; HIF1A PROTEIN, MOUSE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; OXALYLGLYCINE; VASCULOTROPIN A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL OCCLUSION; CONTROLLED STUDY; DISEASE COURSE; DISEASE MODEL; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DOWN REGULATION; ENZYME INHIBITION; EXPERIMENTAL MOUSE; FEMALE; HUMAN; HUMAN CELL; HYPEROXIA; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RETROLENTAL FIBROPLASIA; SIMULATION; AEROBIC METABOLISM; ANIMAL; BIOSYNTHESIS; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; DRUG POTENTIATION; ENZYMOLOGY; KIDNEY; LIVER; METABOLISM; NEWBORN; RETINA;

AEROBIOSIS; AMINO ACIDS, DICARBOXYLIC; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; ERYTHROPOIETIN; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INFANT, NEWBORN; KIDNEY; LIVER; MICE; OXYGEN; PROCOLLAGEN-PROLINE DIOXYGENASE; RETINA; RETINOPATHY OF PREMATURITY; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 58149374572     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0805817105     Document Type: Article

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