-
1
-
-
0001907229
-
Pharmacology and drug therapy
-
CASSIDY JT, PETTY RE (Eds.): 4th ed., Philadelphia, WB Saunders Company
-
LAXER RM, GAZARIAN M: Pharmacology and drug therapy. In CASSIDY JT, PETTY RE (Eds.): Textbook of Pediatric Rheumatology. 4th ed., Philadelphia, WB Saunders Company, 2001: 104.
-
(2001)
Textbook of Pediatric Rheumatology
, pp. 104
-
-
Laxer, R.M.1
Gazarian, M.2
-
2
-
-
0032817678
-
Methotrexate and leflunomide: biochemical basis for combination therapy in the treatment of rheumatoid arthritis
-
KREMER JM: Methotrexate and leflunomide: biochemical basis for combination therapy in the treatment of rheumatoid arthritis. Semin Arthritis Rheum 1999; 29: 14-26.
-
(1999)
Semin Arthritis Rheum
, vol.29
, pp. 14-26
-
-
Kremer, J.M.1
-
3
-
-
3142746016
-
A randomized trial of parenteral methotrexate comparing an intermediate dose with a higher dose in children with juvenile idiopathic arthritis who failed to respond to standard doses of methotrexate
-
RUPERTO N, MURRAY KJ, GERLONI V et al.: A randomized trial of parenteral methotrexate comparing an intermediate dose with a higher dose in children with juvenile idiopathic arthritis who failed to respond to standard doses of methotrexate. Arthritis Rheum 2004; 50: 2191-201.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 2191-2201
-
-
Ruperto, N.1
Murray, K.J.2
Gerloni, V.3
-
4
-
-
0030960980
-
Preliminary definition of improvement in juvenile arthritis
-
GIANNINI EH, RUPERTO N, RAVELLI A, LOVELL DJ, FELSON DT, MARTINI A: Preliminary definition of improvement in juvenile arthritis. Arthritis Rheum 1997; 40: 1202-9.
-
(1997)
Arthritis Rheum
, vol.40
, pp. 1202-1209
-
-
Giannini, E.H.1
Ruperto, N.2
Ravelli, A.3
Lovell, D.J.4
Felson, D.T.5
Martini, A.6
-
5
-
-
79957483535
-
2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: initiation and safety monitoring of therapeutic agents for the treatment of arthritis and systemic features
-
BEUKELMAN T, PATKAR NM, SAAG KG et al.: 2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: initiation and safety monitoring of therapeutic agents for the treatment of arthritis and systemic features. Arthritis Care Res 2011; 63: 465-82.
-
(2011)
Arthritis Care Res
, vol.63
, pp. 465-482
-
-
Beukelman, T.1
Patkar, N.M.2
Saag, K.G.3
-
6
-
-
0029591467
-
The immunosuppressant leflunomide inhibits lymphocyte proliferation by inhibiting pyrimidine biosynthesis
-
CHERWINSKI HM, COHN RG, CHEUNG P et al.: The immunosuppressant leflunomide inhibits lymphocyte proliferation by inhibiting pyrimidine biosynthesis. J Pharmacol Exp Ther 1995; 275: 1043-9.
-
(1995)
J Pharmacol Exp Ther
, vol.275
, pp. 1043-1049
-
-
Cherwinski, H.M.1
Cohn, R.G.2
Cheung, P.3
-
7
-
-
0031865023
-
Mechanism of action of leflunomide in rheumatoid arthritis
-
FOX RI: Mechanism of action of leflunomide in rheumatoid arthritis. J Rheumatol 1998; 53 (Suppl.): 20-6.
-
(1998)
J Rheumatol
, vol.53
, pp. 20-26
-
-
Fox, R.I.1
-
8
-
-
0032555586
-
Leflunomide inhibits pyrimidine de novo synthesis in mitogen-stimulated T-lymphocytes from healthy humans
-
RUCKEMANN K, FAIRBANKS LD, CARREY EA et al.: Leflunomide inhibits pyrimidine de novo synthesis in mitogen-stimulated T-lymphocytes from healthy humans. J Biol Chem 1998; 273: 21682-91.
-
(1998)
J Biol Chem
, vol.273
, pp. 21682-21691
-
-
Ruckemann, K.1
Fairbanks, L.D.2
Carrey, E.A.3
-
9
-
-
0033509841
-
Pharmacokinetics, safety and efficacy of combination treatment with methotrexate and leflunomide in patients with active rheumatoid arthritis
-
WEINBLATT ME, KREMER JM, COBLYN JS et al.: Pharmacokinetics, safety and efficacy of combination treatment with methotrexate and leflunomide in patients with active rheumatoid arthritis. Arthritis Rheum 1999: 42: 1322-8.
-
(1999)
Arthritis Rheum
, vol.42
, pp. 1322-1328
-
-
Weinblatt, M.E.1
Kremer, J.M.2
Coblyn, J.S.3
-
10
-
-
0029959051
-
The rationale for combination therapy of rheumatoid arthritis based on pathophysiology
-
HARRIS ED Jr: The rationale for combination therapy of rheumatoid arthritis based on pathophysiology. J Rheumatol 1996; 44 (Suppl.): 2-4.
-
(1996)
J Rheumatol
, vol.44
, pp. 2-4
-
-
Harris, E.D.1
-
11
-
-
0037027427
-
Concomitant leflunomide therapy in patients with active rheumatoid arthritis despite stable doses of methotrexate-a randomized, double-blind, placebo-controlled trial
-
KREMER JM, GENOVESE MC, CANNON GW et al.: Concomitant leflunomide therapy in patients with active rheumatoid arthritis despite stable doses of methotrexate-a randomized, double-blind, placebo-controlled trial. Ann Intern Med 2002; 137: 726-33.
-
(2002)
Ann Intern Med
, vol.137
, pp. 726-733
-
-
Kremer, J.M.1
Genovese, M.C.2
Cannon, G.W.3
-
12
-
-
25544435304
-
Leflunomide (LEF) as initial therapy with methotrexate (MTX) added for rheumatoid arthritis patients with active disease
-
COHEN S, SCHIFF M, WEAVER A, TESSER J, BARAF H, MAESTRELLO S: Leflunomide (LEF) as initial therapy with methotrexate (MTX) added for rheumatoid arthritis patients with active disease. Arthritis Rheum 2002; 46 (Suppl.): S352.
-
(2002)
Arthritis Rheum
, vol.46
, pp. S352
-
-
Cohen, S.1
Schiff, M.2
Weaver, A.3
Tesser, J.4
Baraf, H.5
Maestrello, S.6
-
13
-
-
20244384845
-
Leflunomide or methotrexate for juvenile rheumatoid arthritis
-
SILVERMAN E, MOUY R, SPIEGEL L et al.: Leflunomide or methotrexate for juvenile rheumatoid arthritis. N Engl J Med 2005; 352: 1655-66.
-
(2005)
N Engl J Med
, vol.352
, pp. 1655-1666
-
-
Silverman, E.1
Mouy, R.2
Spiegel, L.3
-
14
-
-
13444250899
-
Long-term open-label preliminary study of the safety and efficacy of leflunomide in patients with polyarticular-course juvenile rheumatoid arthritis
-
SILVERMAN E, SPIEGEL L, HAWKINS D et al.: Long-term open-label preliminary study of the safety and efficacy of leflunomide in patients with polyarticular-course juvenile rheumatoid arthritis. Arthritis Rheum 2005; 52: 554-62.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 554-562
-
-
Silverman, E.1
Spiegel, L.2
Hawkins, D.3
-
15
-
-
77955484340
-
Effectiveness of leflunomide in patients with juvenile idio-pathic arthritis in clinical practice
-
FOELDVARI I, WIERK A: Effectiveness of leflunomide in patients with juvenile idio-pathic arthritis in clinical practice. J Rheumatol 2010; 37: 1763-7.
-
(2010)
J Rheumatol
, vol.37
, pp. 1763-1767
-
-
Foeldvari, I.1
Wierk, A.2
-
16
-
-
84939535152
-
One-year observation of leflunomide effectiveness and safety in juvenile idiopathic arthritis: a clinical practice review (preliminary data)
-
SEGARRA VT, SANTIN P, CASAS L et al.: One-year observation of leflunomide effectiveness and safety in juvenile idiopathic arthritis: a clinical practice review (preliminary data). Pediatric Rheumatology 2011; 9 (Suppl. 1): P 176.
-
(2011)
Pediatric Rheumatology
, vol.9
, pp. 176
-
-
Segarra, V.T.1
Santin, P.2
Casas, L.3
-
17
-
-
84869202259
-
Leflunomide in systemic onset juvenile idiopathic arthritis
-
JAHAN A, DEWAN V, YADAV TP: Leflunomide in systemic onset juvenile idiopathic arthritis. Indian Pediatr 2012; 49: 750-2.
-
(2012)
Indian Pediatr
, vol.49
, pp. 750-752
-
-
Jahan, A.1
Dewan, V.2
Yadav, T.P.3
-
18
-
-
7544222361
-
Preliminary criteria for clinical remission for select categories of juvenile idiopathic arthritis
-
WALLACE CA, RUPERTO N, GIANNINI EH: Preliminary criteria for clinical remission for select categories of juvenile idiopathic arthritis. J Rheumatol 2004; 31: 2290-4.
-
(2004)
J Rheumatol
, vol.31
, pp. 2290-2294
-
-
Wallace, C.A.1
Ruperto, N.2
Giannini, E.H.3
-
19
-
-
0033843584
-
Methotrexate in juvenile idiopathic arthritis: answers and questions
-
RAVELLI A, MARTINI A: Methotrexate in juvenile idiopathic arthritis: answers and questions. J Rheumatol 2000; 27: 1830-3.
-
(2000)
J Rheumatol
, vol.27
, pp. 1830-1833
-
-
Ravelli, A.1
Martini, A.2
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