5-HT1B receptor imaging and cognition: A positron emission tomography study in control subjects and parkinson's disease patients

Synapse

Volumn 69, Issue 7, 2015, Pages 365-374

  Varrone, Andrea ^a,b   Svenningsson, Per ^a,b   Marklund, Petter ^b,c   Fatouros Bergman, Helena ^a   Forsberg, Anton ^a   Halldin, Christer ^a,b   Nilsson, Lars Göran ^b,c   Farde, Lars ^a,b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b Stockholm Brain Institute   (Sweden)

^c STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

Cognition; Creativity; PET; Semantic memory; Serotonin

Indexed keywords

AZ10419369 C 11; RADIOLIGAND; SEROTONIN 1B RECEPTOR; UNCLASSIFIED DRUG; 5-METHYL-8-(4-METHYL-PIPERAZIN-1-YL)-4-OXO-4H-CHROMENE-2-CARBOXYLIC ACID (4-MORPHOLIN-4-YL-PHENYL)AMIDE; BENZOPYRAN DERIVATIVE; MORPHOLINE DERIVATIVE; PIPERAZINE DERIVATIVE; PROTEIN BINDING;

AGED; ARTICLE; BECK DEPRESSION INVENTORY; BRAIN; BRAIN SIZE; CLINICAL ARTICLE; CLINICAL EVALUATION; COGNITION; CONTROLLED STUDY; DEPRESSION; DISEASE DURATION; EPISODIC MEMORY; FATIGUE; FEMALE; GRAY MATTER; HUMAN; MALE; MINI MENTAL STATE EXAMINATION; MONTGOMERY ASBERG DEPRESSION RATING SCALE; PARKINSON DISEASE; PERCEPTIVE THRESHOLD; POSITRON EMISSION TOMOGRAPHY; PREVALENCE; PRIORITY JOURNAL; RESPONSE TIME; SEMANTIC MEMORY; UNIFIED PARKINSON DISEASE RATING SCALE; VOXEL BASED MORPHOMETRY; WORKING MEMORY; ANALYSIS OF VARIANCE; COGNITION DISORDERS; COMPLICATION; DRUG EFFECTS; METABOLISM; MIDDLE AGED; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; SCINTISCANNING; SEVERITY OF ILLNESS INDEX;

AGED; ANALYSIS OF VARIANCE; BENZOPYRANS; BRAIN; COGNITION DISORDERS; FEMALE; GRAY MATTER; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MORPHOLINES; NEUROPSYCHOLOGICAL TESTS; PARKINSON DISEASE; PIPERAZINES; POSITRON-EMISSION TOMOGRAPHY; PROTEIN BINDING; RECEPTOR, SEROTONIN, 5-HT1B; SEVERITY OF ILLNESS INDEX;

EID: 84929919379     PISSN: 08874476     EISSN: 10982396     Source Type: Journal    
DOI: 10.1002/syn.21823     Document Type: Article

References (46)

1. Andersson JD, Pierson ME, Finnema SJ, Gulyas B, Heys R, Elmore CS, Farde L, Halldin C. 2011. Development of a PET radioligand for the central 5-HT1B receptor: Radiosynthesis and characterization in cynomolgus monkeys of eight radiolabeled compounds. Nucl Med Biol 38:261-272.
2. Barone P, Aarsland D, Burn D, Emre M, Kulisevsky J, Weintraub D. 2011. Cognitive impairment in nondemented parkinson's disease. Mov Disord 26:2483-2495.
3. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. 1961. An inventory for measuring depression. Arch Gen Psychiatry 4:561-571.
4. Benedek M, Jauk E, Sommer M, Arendasy M, Neubauer AC. 2014. Intelligence, creativity, and cognitive control: The common and differential involvement of executive functions in intelligence and creativity. Intelligence 46:73-83.
5. Bodis-Wollner I. 2003. Neuropsychological and perceptual defects in Parkinson's disease. Parkinsonism Relat Disord 9 Suppl 2:S83-89.
6. Bublak P, Redel P, Finke K. 2006. Spatial and non-spatial attention deficits in neurodegenerative diseases: Assessment based on bundesen's theory of visual attention (TVA). Restor Neurol Neurosci 24:287-301.
7. Buhot MC, Martin S, Segu L. 2000. Role of serotonin in memory impairment. Ann Med 32:210-221.
8. Bundesen C. 1990. A theory of visual attention. Psychol Rev 97:523-547.
9. Cselenyi Z, Olsson H, Halldin C, Gulyas B, Farde L. 2006. A comparison of recent parametric neuroreceptor mapping approaches based on measurements with the high affinity PET radioligands [11C]FLB 457 and [11C]WAY 100635. Neuroimage 32:1690-1708.
10. de Manzano O, Cervenka S, Karabanov A, Farde L, Ullen F. 2010. Thinking outside a less intact box: thalamic dopamine d2 receptor densities are negatively related to psychometric creativity in healthy individuals. PLoS One 5:e10670-
11. DeMoss K, Milich R, DeMers S. 1993. Gender, creativity, depression, and attributional style in adolescents with high academic ability. J Abnorm Child Psychol 21:455-467.
12. Desikan RS, Segonne F, Fischl B, Quinn BT, Dickerson BC, Blacker D, Buckner RL, Dale AM, Maguire RP, Hyman BT, Albert MS, Killiany RJ. 2006. An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest. Neuroimage 31:968-980.
13. Dietrich A, Kanso R. 2010. A review of EEG, ERP, and neuroimaging studies of creativity and insight. Psychol Bull 136:822-848.
14. Drago V, Foster PS, Skidmore FM, Heilman KM. 2009. Creativity in parkinson's disease as a function of right versus left hemibody onset. J Neurol Sci 276:179-183.
15. Dujardin K, Leentjens AF, Langlois C, Moonen AJ, Duits AA, Carette AS, Duhamel A. 2013. The spectrum of cognitive disorders in parkinson's disease: a data-driven approach. Mov Disord 28:183-189.
16. Fischl B, Salat DH, Busa E, Albert M, Dieterich M, Haselgrove C, van der Kouwe A, Killiany R, Kennedy D, Klaveness S, Montillo A, Makris N, Rosen B, Dale AM. 2002. Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain. Neuron 33:341-355.
17. Fischl B, Salat DH, van der Kouwe AJ, Makris N, Segonne F, Quinn BT, Dale AM. 2004a. Sequence-independent segmentation of magnetic resonance images. Neuroimage 23 Suppl 1:S69-84.
18. Fischl B, van der Kouwe A, Destrieux C, Halgren E, Segonne F, Salat DH, Busa E, Seidman LJ, Goldstein J, Kennedy D, Caviness V, Makris N, Rosen B, Dale AM. 2004b. Automatically parcellating the human cerebral cortex. Cereb Cortex 14:11-22.
19. Gibb WR, Lees AJ. 1988. The relevance of the lewy body to the pathogenesis of idiopathic parkinson's disease. J Neurol Neurosurg Psychiatry 51:745-752.
20. Guilford JP. 1967. The Nature of Human Intelligence. New York: McGraw-Hill.
21. Higginson CI, King DS, Levine D, Wheelock VL, Khamphay NO, Sigvardt KA. 2003. The relationship between executive function and verbal memory in parkinson's disease. Brain Cogn 52:343-352.
22. Inzelberg R. 2013. The awakening of artistic creativity and parkinson's disease. Behav Neurosci 127:256-261.
23. Jacobs BL, Fornal CA. 1999. Activity of serotonergic neurons in behaving animals. Neuropsychopharmacology 21(2 Suppl):9S-15S.
24. Jäger AO, Süß HM, Beauducel A. 1997. Berliner Intelligenzstruktur-Test (BIS-Test): Form 4. Göttingen: Hogrefe.
25. Johnson SL, Murray G, Fredrickson B, Youngstrom EA, Hinshaw S, Bass JM, Deckersbach T, Schooler J, Salloum I. 2012. Creativity and bipolar disorder: touched by fire or burning with questions? Clin Psychol Rev 32:1-12.
26. Joutsa J, Martikainen K, Kaasinen V. 2012. Parallel appearance of compulsive behaviors and artistic creativity in parkinson's disease. Case Rep Neurol 4:77-83.
27. Kemps E, Szmalec A, Vandierendonck A, Crevits L. 2005. Visuo-spatial processing in parkinson's disease: evidence for diminished visuo-spatial sketch pad and central executive resources. Parkinsonism Relat Disord 11:181-186.
28. Kirchner WK. 1958. Age differences in short-term retention of rapidly changing information. J Exp Psychol 55:352-358.
29. Ludwig AM. 1994. Mental illness and creative activity in female writers. Am J Psychiatry 151:1650-1656.
30. McElree B. 2001. Working memory and focal attention. J Exp Psychol Learn Mem Cogn 27:817-835.
31. Miyake A, Friedman NP, Rettinger DA, Shah P, Hegarty M. 2001. How are visuospatial working memory, executive functioning, and spatial abilities related? A latent variable analysis. J Exp Psychol 130:621-640.
32. Montgomery SA, Asberg M. 1979. A new depression scale designed to be sensitive to change. Br J Psychiatry 134:382-389.
33. Nilsson LG, Adolfsson R, Bäckman L, de Frias C, Molander B, Nyberg L. 2004. Betula: A prospective cohort study on memory, health and aging. Aging Neuropsychol Cogn 11:134-148.
34. Nord M, Cselenyi Z, Forsberg A, Rosenqvist G, Tiger M, Lundberg J, Varrone A, Farde L. 2014. Distinct regional age effects on [11C]az10419369 binding to 5-HT1B receptors in the human brain. Neuroimage 103:303-308.
35. Poewe W. 2008. Non-motor symptoms in Parkinson's disease. Eur J Neurol 15 Suppl 1:14-20.
36. Reuter M, Roth S, Holve K, Hennig J. 2006. Identification of first candidate genes for creativity: A pilot study. Brain Res 1069:190-197.
37. Schain M, Toth M, Cselenyi Z, Stenkrona P, Halldin C, Farde L, Varrone A. 2011. quantification of serotonin transporter availability with [(11)C]MADAM - a comparison between the ECAT HRRT and HR systems. Neuroimage 60:800-807.
38. Schlagenhauf F, Rapp MA, Huys QJ, Beck A, Wustenberg T, Deserno L, Buchholz HG, Kalbitzer J, Buchert R, Bauer M, Kienast T, Cumming P, Plotkin M, Kumakura Y, Grace AA, Dolan RJ, Heinz A. 2013. Ventral striatal prediction error signaling is associated with dopamine synthesis capacity and fluid intelligence. Hum Brain Mapp 34:1490-1499.
39. Schuldberg D. 2001. Six subclinical spectrum traits in normal creativity. Creat Res J 13:5-16.
40. Shohamy D, Myers CE, Grossman S, Sage J, Gluck MA. 2005. The role of dopamine in cognitive sequence learning: Evidence from parkinson's disease. Behav Brain Res 156:191-199.
41. Takeuchi H, Taki Y, Hashizume H, Sassa Y, Nagase T, Nouchi R, Kawashima R. 2012. The association between resting functional connectivity and creativity. Cereb Cortex 22:2921-2929.
42. Ukkola-Vuoti L, Kanduri C, Oikkonen J, Buck G, Blancher C, Raijas P, Karma K, Lahdesmaki H, Jarvela I. 2013. Genome-wide copy number variation analysis in extended families and unrelated individuals characterized for musical aptitude and creativity in music. PLoS One 8:e56356-
43. Varnas K, Halldin C, Hall H. 2004. Autoradiographic distribution of serotonin transporters and receptor subtypes in human brain. Hum Brain Mapp 22:246-260.
44. Varrone A, Sjoholm N, Eriksson L, Gulyas B, Halldin C, Farde L. 2009. Advancement in PET quantification using 3D-OP-OSEM point spread function reconstruction with the HRRT. Eur J Nucl Med Mol Imaging 36:1639-1650.
45. Varrone A, Svenningsson P, Forsberg A, Varnas K, Tiger M, Nakao R, Halldin C, Nilsson LG, Farde L. 2014. Positron emission tomography imaging of 5-hydroxytryptamine1B receptors in parkinson's disease. Neurobiol Aging 35:867-875.
46. Volf NV, Kulikov AV, Bortsov CU, Popova NK. 2009. Association of verbal and figural creative achievement with polymorphism in the human serotonin transporter gene. Neurosci Lett 463:154-157.