Spatial and non-spatial attention deficits in neurodegenerative diseases: Assessment based on Bundesen's theory of visual attention (TVA)

Restorative Neurology and Neuroscience

Volumn 24, Issue 4-6, 2006, Pages 287-301

  Bublak, Peter ^a,b   Redel, Petra ^b   Finke, Kathrin ^b  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

Alzheimer's disease; Hemispatial neglect; Huntington's disease; Neuropsychological tests; Neuropsychology; Perceptual disorders

Indexed keywords

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; ATTENTION DEFICIT DISORDER; COGNITIVE DEFECT; CONTROLLED STUDY; DEGENERATIVE DISEASE; FEMALE; HUMAN; HUMAN EXPERIMENT; HUNTINGTON CHOREA; MALE; MEMORY CONSOLIDATION; NEUROPSYCHOLOGICAL TEST; PERCEPTION; PERCEPTION DISORDER; PRIORITY JOURNAL; WORKING MEMORY;

AGED; ALZHEIMER DISEASE; ATTENTION; HUMANS; HUNTINGTON DISEASE; NEURODEGENERATIVE DISEASES; NEUROPSYCHOLOGICAL TESTS; PERCEPTUAL DISORDERS; VISUAL PERCEPTION;

EID: 33751103457     PISSN: 09226028     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (79)

1. G.E. Alexander, M.R. De Long and P.L. Strick, Parallel organization of functionally segregated circuits linking basal ganglia and cortex, Annual Review of Neuroscience 9 (1986), 357-381.
2. X.A. Alvarez, R. Mouzo, V. Pichel, P. Perez, M. Laredo, E. Fernandez-Novoa, L. Corzo, R. Zas, M. Alcarez, J.J. Secades, R. Lozano and R. Cacabelos, Double-blind placebo-controlled study with citicoline in APOE genotyped Alzheimer's disease patients. Effects on cognitive performance, brain bioelectrical activity and cerebral perfusion, Methods and Findings in Experimental and Clinical Pharmacology 21 (1999), 633-644.
3. T.C. Andrews and D.J. Brooks, Advances in the understanding of early Huntington's disease using the functional imaging techniques of PET and SPET, Molecular Medicine Today 4 (1998), 532-539.
4. E.H. Aylward, N.B. Anderson, F.W. Bylsma, M.V. Wagster, P.E. Barta, M. Sherr, J. Feeney, A. Davis, A. Rosenblatt, G.D. Pearlson and C.A. Ross, Frontal lobe volume in patients with Huntington's disease, Neurology 50 (1998), 252-258.
5. P. Bartolomeo, G. Dalla Barba, M.F. Boisse, A.C. Bachoud-Levi, J.D. Degos and F. Boller, Right-side neglect in Alzheimer's disease, Neurology 51 (1998), 1207-1209.
6. P. Bublak, K. Finke, J. Krummenacher, R. Preger, S. Kyllingsbæk, H.J. Müller and W.X. Schneider, Usability of a theory of visual attention (TVA) for parameter-based measurement of attention II: evidence from two patients with frontal or parietal damage, Journal of the International Neuropsychological Society 11 (2005), 843-854.
7. P. Bublak, P. Redel, C. Sorg and K. Finke, Top-down-control and spatial attention in mild cognitive impairment and Alzheimer's disease: parametric assessment based on a theory of visual attention (TVA), Joint Meeting of the German Society of Neuropsychology and the International Neuropsychological Society, Zurich, Switzerland, 2006.
8. C. Bundesen, A theory of visual attention, Psychological Review 97 (1990), 523-547.
9. C. Bundesen, A computational theory of visual attention, Philosophical Transactions of the Royal Society London B 353 (1998), 1271-1281.
10. C. Bundesen, A general theory of visual attention, in: Psychology at the turn of the millennium: Vol. 1. Cognitive, biological, and health perspectives, L. Bäckman and C. von Hofsten, eds, Psychology Press, Hove, 2002, pp. 179-200.
11. C. Bundesen, T. Habekost and S. Kyllingsbæk, A neural theory of visual attention: bridging cognition and neurophysiology, Psychological Review 112 (2005), 291-328.
12. T.W. Chow and J.L. Cummings, Frontal-subcortical circuits, in: The human frontal lobes, B.L. Miller and J.L. Cummings, eds, Guilford Press, New York, 1999, pp. 3-26.
13. A.R. Damasio, H. Damasio and H.C. Chui, Neglect following damage to frontal lobe or basal ganglia, Neuropsychologia 18 (1980), 123-132.
14. J. Danckert and S. Ferber, Revisiting unilateral neglect, Neuropsychologia 44 (2006), 987-1006.
15. R. Desimone, Visual attention mediated by biased competition in extrastriate visual cortex, Philosophical Transactions of the Royal Society London B 353 (1998), 1245-1255.
16. R. Desimone and J. Duncan, Neural mechanisms of selective visual attention, Annual Review of Psychology 18 (1995), 193-222.
17. J. Driver and P. Vuilleumier, Perceptual awareness and its loss in unilateral neglect and extinction, Cognition 79 (2001), 39-88.
18. J. Duncan, C. Bundesen, A. Olson, G. Humphreys, S. Chavda and H. Shibuya, Systematic analysis of deficits in visual attention, Journal of Experimental Psychology: General 128 (1999), 450-478.
19. J. Duncan, C. Bundesen, A. Olson, G. Humphreys, R. Ward, S. Kyllingsbæk, M. Van Raamsdonk, C. Rorden and S. Chavda, Attentional functions in dorsal and ventral simultanagnosia, Cognitive Neuropsychology 20 (2003), 675-702.
20. J. Duncan, G. Humphreys and R. Ward, Competitive brain activity in visual attention, Current Opinion in Neurobiology 7 (1997), 255-261.
21. J. Fan, B.D. McCandliss, T. Sommer, A. Raz and M.I. Posner, Testing the efficiency and independence of attentional networks, Journal of Cognitive Neuroscience 14 (2002), 340-347.
22. B. Fimm, R. Zahn, M. Mull, S. Kemeny, F. Buchwald, F. Block and M. Schwarz, Asymmetries of visual attention after circumscribed subcortical vascular lesions, Journal of Neurology Neurosurgery, and Psychiatry 71 (2001), 652-657.
23. K. Finke, P. Bublak, M. Dose, H.J. Müller and W.X. Schneider, Parameter-based assessment of spatial and non-spatial attentional deficits in Huntington's disease, Brain 129 (2006), 1137-1151.
24. K. Finke, P. Bublak, J. Krummenacher, S. Kyllingsbæk, H.J. Müller and W.X. Schneider, Usability of a theory of visual attention (TVA) for parameter-based measurement of attention I: evidence from normal subjects, Journal of the International Neuropsychological Society 11 (2005), 832-842.
25. N.L. Foster, T.N. Chase, L. Mansi, R. Brooks, P. Fedio, N.J. Patronas and G. Di Chiro, Cortical abnormalities in Alzheimer's disease, Brain Research 691 (1984), 83-91.
26. I. Freedman and L.E. Dexter, Visuospatial ability in cortical dementia, Journal of Clinical and Experimental Neuropsychology 13 (1991), 677-690.
27. R.J. Friedrich, R. Egly, R.D. Rafal and D. Beck, Spatial attention deficits in humans: a comparison of superior parietal and temporal-parietal junction lesions, Neuropsychology 12 (1998), 193-207.
28. D. Glocker, P. Bittl and G. Kerkhoff, Construction and psychometric properties of a novel test for body representational neglect (Vest Test), Restorative Neurology and Neuroscience this issue, (2006).
29. T. Habekost and C. Bundesen, Patient assessment based on a theory of visual attention (TVA): subtle deficits after a right frontal-subcortical lesion, Neuropsychologia 41 (2003), 1171-1188.
30. T. Habekost and E. Rostrup, Persisting asymmetries of vision after right side lesions, Neuropsychologia 44 (2006), 876-895.
31. K. Herholz, FDG PET and differential diagnosis of dementia, Alzheimer Disease and Associated Disorders 9 (1995), 6-16.
32. O. Hikosaka, Y. Takikawa and R. Kawagoe, Role of the basal ganglia in the control of purposive saccadic eye movements, Physiological Reviews 80 (2000), 953-978.
33. M. Husain, S. Mannan, T. Hodgson, E. Wojciulik, J. Driver and C. Kennard, Impaired spatial working memory across saccades contributes to abnormal search in parietal neglect, Brain 124 (2001), 941-952.
34. M. Husain and C. Rorden, Non-spatially lateralized mechanisms in hemispatial neglect, Nature Reviews Neuroscience 4 (2003), 26-36.
35. S. Ishiai, K. Seki, Y. Koyama and R. Okiyama, Effects of cueing on visuospatial processing in unilateral spatial neglect, Journal of Neurology 242 (1995), 367-373.
36. W.J. Jagust, J.L. Eberling, B.R. Reed, C.A. Mathis and T.F. Budinger, Clinical studies of cerebral blood flow in Alzheimer's disease, Neurology 50 (1997), 1585-1593.
37. H.-O. Karnath, A.D. Milner and G. Vallar, The cognitive and neural bases of spatial neglect, Oxford University Press, Oxford, 2002.
38. S. Kastner and L. Ungerleider, Mechanisms of visual attention in the human cortex, Annual Review of Neuroscience 23 (2000), 315-341.
39. C.M. Kipps, A.J. Duggins, N. Mahant, L. Gomes, J. Ashburner and E.A. McCusker, Progression of structural neuropathology in preclinical Huntington's disease: a tensor based morphometry study, Journal of Neurology Neurosurgery, and Psychiatry 75 (2005), 650-655.
40. D. Kogure, H. Matsuda, T. Ohnishi, T. Asada, M. Uno, T. Kunihiro, S. Nakano and M. Takasaki, Longitudinal evaluation of early Alzheimer's disease using brain perfusion SPECT, Journal of Nuclear Medicine 41 (2000), 1155-1162.
41. S. Kyllingsbæk, Modeling visual attention, Behavior Research Methods 38 (2006), 123-133.
42. F. Li, E. Iseki, M. Kato, Y. Adachi, M. Akagi and K. Kosaka, An autopsy case of Alzheimer's disease presenting with primary progressive aphasia: a clinicopathological and immunohistochemial study, Neuropathology 20 (2000), 239-245.
43. N.B. Lincoln and A. Bowen, The need for randomised treatment studies in neglect research, Restorative Neurology and Neuroscience, this issue, (2006).
44. P. Malhotra, H.R. Jäger, A. Parton, R. Greenwood, E.D. Playford, M.M. Brown, J. Driver and M. Husain, Spatial working memory capacity in unilateral neglect, Brain 128 (2005), 424-435.
45. T. Manly, Cognitive rehabilitation for unilateral neglect: review, Neuropsychological Rehabilitation 12 (2002), 289-310.
46. C.A. Marzi, M. Girelli, E. Natale and C. Miniussi, What exactly is extinguished in unilateral visual extinction? Neurophysiological evidence, Neuropsychologia 39 (2001), 1354-1366.
47. J.B. Mattingley, N. Berberovic, L. Corben, M.J. Slavin, M.E.R. Nicholls and J.L. Bradshaw, The greyscales task: a perceptual measure of attentional bias following unilateral hemispheric damage, Neuropsychologia 42 (2004), 387-394.
48. M.F. Mendez, M.M. Cherrier and J.S. Cymerman, Hemispatial neglect on visual search tasks in Alzheimer's disease, Neuropsychiatric, Neuropsychological, and Behavioural Neurology 10 (1997), 203-208.
49. M.-M. Mesulam, Spatial attention and neglect: parietal, frontal, and cingulate contributions to the mental representation and attentional targeting of salient extrapersonal events, Philosophical Transactions of the Royal Society London B 354 (1999), 1325-1346.
50. A.D. Milner, Neglect, extinction, and the cortical streams of visual processing, in: Parietal lobe contributions to orientation in 3D space, H.-O. Karnath and P. Thier, eds, Springer, Berlin, 1997, pp. 3-22.
51. A. Parton, P. Malhotra and M. Husain, Hemispatial neglect, Journal of Neurology, Neurosurgery, and Psychiatry 75 (2004), 13-21.
52. J.S. Paulsen, J.L. Zimbelman, S.C. Hinton, D.R. Langbehn, C.L. Leveroni, M.L. Benjamin, N.C. Reynolds and S.M. Rao, fMRI biomarker of early neuronal dysfunction in presymptomatic Huntington's disease, American Journal of Neuroradiology 25 (2004), 1715-1721.
53. P.V. Peers, C.J.H. Ludwig, C. Rorden, R. Cusack, C. Bonfiglioli, C. Bundesen, J. Driver, N. Antoun and J. Duncan, Attentional functions of parietal and frontal cortex, Cerebral Cortex 15 (2005), 1469-1484.
54. R.J. Perry and J.R. Hodges, Attention and executive deficits in Alzheimer's disease: a critical review, Brain 122 (1999), 383-404.
55. P. Redel, P. Bublak, C. Sorg and K. Finke, Perceptual processing speed and visual working memory storage capacity in mild cognitive impairment and Alzheimer's disease: parametric assessment based on a theory of visual attention (TVA), Joint Meeting of the German Society of Neuropsychology and the International Neuropsychological Society, Zurich, Switzerland, 2006.
56. P.A. Reuter-Lorenz and M.I. Posner, Components of neglect from right-hemisphere damage: an analysis of line bisection, Neuropsychologia 28 (1990), 327-333.
57. J.H. Reynolds and R. Desimone, Interacting roles of attention and visual salience in V4, Neuron 37 (2003), 853-863.
58. M.J. Riddoch and G.W. Humphreys, The effect of cueing on unilateral neglect, Neuropsychologia 21 (1983), 589-599.
59. I.H. Robertson, J.B. Mattingley, C. Rorden and J. Driver, Phasic alerting of neglect patients overcomes their spatial deficit in visual awareness, Nature 395 (1998), 169-172.
60. H.D. Rosas, J. Goodman, Y.I. Chen, B.G. Jenkins, D.N. Kennedy, N. Makris, M. Patti, L.J. Seidman, M.F. Beal and W.J. Koroshetz, Striatal volume loss in HD as measured by MRI and the influence of CAG repeat, Neurology 57 (2001), 1025-1028.
61. H.D. Rosas, N.D. Hevelone, A.K. Zaleta, D.N. Greve, D.H. Salat and B. Fischl, Regional cortical thinning in preclinical Huntington disease and its relationship to cognition, Neurology 65 (2005), 745-747.
62. H.D. Rosas, A.K. Liu, S. Hersch, M. Glessner, R.J. Ferrante, D.H. Salat, A. Van der Kouwe, B.G. Jenkins, A.M. Dale and B. Fischl, Regional and progressive thinning of the cortical ribbon in Huntington's disease, Neurology 58 (2002), 695-701.
63. Y. Sakashita, Visual attentional disturbance with unilateral lesions in the basal ganglia and deep white matter, Annals of Neurology 30 (1991), 673-677.
64. W.X. Schneider, VAM: a neuro-cognitive model for visual attention control of segmentation, object recognition, and space based-motor action, Visual Cognition 2 (1995), 331-375.
65. W.X. Schneider, Visual-spatial working memory, attention, and scene representation: a neuro-cognitive theory, Psychological Research 62 (1999), 220-236.
66. H. Shibuya and C. Bundesen, Visual selection from multi-element displays: measuring and modeling effects of exposure duration, Journal of Experimental Psychology: Human Perception and Performance 14 (1988), 591-600.
67. D.J. Simons and D.T. Levin, Change blindness, Trends in Cognitive Sciences 1 (1997), 261-267.
68. G. Sperling, The information available in brief visual presentations, Psychological Monographs 74 (1960), 11.
69. G. Sperling, A model for visual memory tasks, Human Factors 5 (1963), 19-31.
70. M.J. Thieben, A.J. Duggins, C.D. Good, L. Gomes, N. Mahant, F. Richards, E. McCusker and R.S.J. Frackowiack, The distribution of structural neuropathology in pre-clinical Huntington's disease, Brain 125 (2002), 1815-1828.
71. M. Thimm, G.R. Fink, J. Küst, H. Karbe and W. Sturm, Impact of alertness training on spatial neglect: a behavioural and fMRI study, Neuropsychologia 44 (2006), 1230-1246.
72. K. Ueyama, H. Fukuzako, T. Fukuzako, Y. Hokazono, K. Takeuchi, T. Hashiguchi, M. Takigawa, T. Yamanaka and K. Matsumoto, CT study in senile dementia of Alzheimer type, International Journal of Geriatric Psychiatry 9 (1994), 919-924.
73. G. Vallar, Spatial hemineglect in humans, Trends in Cognitive Sciences 2 (1998), 87-97.
74. S.P. Vecera and M. Rizzo, Spatial attention: normal processes and their breakdown, Neurologic Clinics of North America 21 (2003), 575-607.
75. N.D. Volkow, W. Zhu, C.A. Felder, K. Mueller, T.F. Welsh, G.-J. Wang and M.J. de Leon, Changes in brain functional homogeneity in subjects with Alzheimer's disease, Psychiatry Research Neuroimaging 114 (2002), 39-50.
76. S. Weintraub, K.R. Daffner, G.L. Ahern, B.H. Price and M.-M. Mesulam, Right sided hemispatial neglect and bilateral cerebral lesions, Journal Of Neurology, Neurosurgery, and Psychiatry 60 (1996), 342-344.
77. B. Wilson, J.J. Cockburn and P. Halligan, Development of a behavioral test of visuospatial neglect, Archives of Physical Medicine and Rehabilitation 68 (1987), 98-102.
78. E. Wojciulik, M. Husain, K. Clarke and J. Driver, Spatial working memory deficit in unilateral neglect, Neuropsychologia 39 (2001), 390-396.
79. K.K. Zakzanis, The subcortical dementia of Huntington's disease, Journal of Clinical and Experimental Neuropsychology 20 (1998), 565-578.