Correlation between sperm DNA fragmentation index and CMA3 positive spermatozoa in globozoospermic patients

Andrology

Volumn 3, Issue 3, 2015, Pages 526-531

  Hosseinifar, H ^a   Yazdanikhah, S ^a   Modarresi, T ^a   Totonchi, M ^a   Sadighi Gilani, M A ^a,b   Sabbaghian, Marjan ^a  

^a ROYAN INSTITUTE FOR REPRODUCTIVE BIOMEDICINE   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

ChromomycinA3; DNA damage; Protamines; Round head; Spermatozoa

Indexed keywords

CHROMOMYCIN A3; PROTAMINE; CHROMATIN; DNA;

ADULT; ARTICLE; CHROMATIN CONDENSATION; CHROMATIN STRUCTURE; CLINICAL ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA FRAGMENTATION; FLUORESCENCE MICROSCOPY; GLOBOZOOSPERMIA; HUMAN; MALE; PRIORITY JOURNAL; SEMEN ANALYSIS; SPERM; SPERMATOZOON; SPERMATOZOON ABNORMALITY; SPERMATOZOON COUNT; SPERMATOZOON DENSITY; SPERMATOZOON MOTILITY; ACROSOME; CHROMATIN; CYTOLOGY; GENETICS; MALE INFERTILITY; METABOLISM; PATHOLOGY; PHYSIOLOGY; SPERMATOZOON HEAD;

ACROSOME; CHROMATIN; CHROMOMYCIN A3; DNA; DNA FRAGMENTATION; HUMANS; INFERTILITY, MALE; MALE; PROTAMINES; SEMEN ANALYSIS; SPERM COUNT; SPERM HEAD; SPERM MOTILITY; SPERMATOZOA;

EID: 84929834563     PISSN: 20472919     EISSN: 20472927     Source Type: Journal    
DOI: 10.1111/andr.12030     Document Type: Article

References (58)

1. Agarwal A & Said TM. (2003) Role of sperm chromatin abnormalities and DNA damage in male infertility. Hum Reprod Update 9, 331-345.
2. Aitken RJ, Kerr L, Bolton V & Hargreave T. (1990) Analysis of sperm function in globozoospermia: implications for the mechanism of sperm-zona interaction. Fertil Steril 54, 701-707.
3. Alkhayal A, San Gabriel M, Zeidan K, Alrabeeah K, Noel D, Mcgraw R, Bissonnette F, Kadoch IJ & Zini A. (2013) Sperm DNA and chromatin integrity in semen samples used for intrauterine insemination. J Assist Reprod Genet 30, 1519-1524.
4. Alvarez JG, Sharma RK, Ollero M, Saleh RA, Lopez MC, Thomas AJ, Jr, Evenson DP & Agarwal A. (2002) Increased DNA damage in sperm from leukocytospermic semen samples as determined by the sperm chromatin structure assay. Fertil Steril 78, 319-329.
5. Arnon J, Meirow D, Lewis-Roness H & Ornoy A. (2001) Genetic and teratogenic effects of cancer treatments on gametes and embryos. Hum Reprod Update 7, 394-403.
6. Baccetti B, Collodel G & Piomboni P. (1996) Apoptosis in human ejaculated sperm cells (notulae seminologicae 9). J Submicrosc Cytol Pathol 28, 587-596.
7. Blanchard Y, Lescoat D & Le Lannou D. (1990) Anomalous distribution of nuclear basic proteins in round-headed human spermatozoa. Andrologia 22, 549-555.
8. Boe-Hansen GB, Ersboll AK & Christensen P. (2005) Variability and laboratory factors affecting the sperm chromatin structure assay in human semen. J Androl 26, 360-368.
9. Brahem S, Mehdi M, Elghezal H & Saad A. (2011) Analysis of sperm aneuploidies and DNA fragmentation in patients with globozoospermia or with abnormal acrosomes. Urology 77, 1343-1348.
10. Bungum M, Humaidan P, Spano M, Jepson K, Bungum L & Giwercman A. (2004) The predictive value of sperm chromatin structure assay (SCSA) parameters for the outcome of intrauterine insemination, IVF and ICSI. Hum Reprod 19, 1401-1408.
11. Bungum M, Humaidan P, Axmon A, Spano M, Bungum L, Erenpreiss J & Giwercman A. (2007) Sperm DNA integrity assessment in prediction of assisted reproduction technology outcome. Hum Reprod 22, 174-179.
12. Bungum M, Spano M, Humaidan P, Eleuteri P, Rescia M & Giwercman A. (2008) Sperm chromatin structure assay parameters measured after density gradient centrifugation are not predictive for the outcome of ART. Hum Reprod 23, 4-10.
13. Carrell DT, Emery BR & Liu L. (1999) Characterization of aneuploidy rates, protamine levels, ultrastructure, and functional ability of round-headed sperm from two siblings and implications for intracytoplasmic sperm injection. Fertil Steril 71, 511-516.
14. Chatterjee R, Haines GA, Perera DM, Goldstone A & Morris ID. (2000) Testicular and sperm DNA damage after treatment with fludarabine for chronic lymphocytic leukaemia. Hum Reprod 15, 762-766.
15. Coutton C, Zouari R, Abada F, Ben Khelifa M, Merdassi G, Triki C, Escalier D, Hesters L, Mitchell V, Levy R, Sermondade N, Boitrelle F, Vialard F, Satre V, Hennebicq S, Jouk PS, Arnoult C, Lunardi J & Ray PF. (2012) MLPA and sequence analysis of DPY19L2 reveals point mutations causing globozoospermia. Hum Reprod 27, 2549-2558.
16. Dale B, Iaccarino M, Fortunato A, Gragnaniello G, Kyozuka K & Tosti E. (1994) A morphological and functional study of fusibility in round-headed spermatozoa in the human. Fertil Steril 61, 336-340.
17. Dam AH, Feenstra I, Westphal JR, Ramos L, Van Golde RJ & Kremer JA. (2007) Globozoospermia revisited. Hum Reprod Update 13, 63-75.
18. Egashira A, Murakami M, Haigo K, Horiuchi T & Kuramoto T. (2009) A successful pregnancy and live birth after intracytoplasmic sperm injection with globozoospermic sperm and electrical oocyte activation. Fertil Steril 92, 2037 e5-e9.
19. Elinati E, Kuentz P, Redin C, Jaber S, Vanden Meerschaut F, Makarian J, Koscinski I, Nasr-Esfahani MH, Demirol A, Gurgan T, Louanjli N, Iqbal N, Bisharah M, Pigeon FC, Gourabi H, De Briel D, Brugnon F, Gitlin SA, Grillo JM, Ghaedi K, Deemeh MR, Tanhaei S, Modarres P, Heindryckx B, Nikiforaki D, Oehninger SC, De Sutter P, Muller J & Viville S. (2012) Globozoospermia is mainly due to DPY19L2 deletion via non-allelic homologous recombination involving two recombination hotspots. Hum Mol Genet 21, 3695-3702.
20. Erenpreiss J, Hlevicka S, Zalkalns J & Erenpreisa J. (2002) Effect of leukocytospermia on sperm DNA integrity: a negative effect in abnormal semen samples. J Androl 23, 717-723.
21. Evenson DP, Jost LK, Marshall D, Zinaman MJ, Clegg E, Purvis K, De Angelis P & Claussen OP. (1999) Utility of the sperm chromatin structure assay as a diagnostic and prognostic tool in the human fertility clinic. Hum Reprod 14, 1039-1049.
22. Evenson DP, Larson KL & Jost LK. (2002) Sperm chromatin structure assay: its clinical use for detecting sperm DNA fragmentation in male infertility and comparisons with other techniques. J Androl 23, 25-43.
23. Hamberger L, Lundin K, Sjogren A & Soderlund B. (1998) Indications for intracytoplasmic sperm injection. Hum Reprod 13(Suppl 1), 128-133.
24. Harbuz R, Zouari R, Pierre V, Ben Khelifa M, Kharouf M, Coutton C, Merdassi G, Abada F, Escoffier J, Nikas Y, Vialard F, Koscinski I, Triki C, Sermondade N, Schweitzer T, Zhioua A, Zhioua F, Latrous H, Halouani L, Ouafi M, Makni M, Jouk PS, Sele B, Hennebicq S, Satre V, Viville S, Arnoult C, Lunardi J & Ray PF. (2011) A recurrent deletion of DPY19L2 causes infertility in man by blocking sperm head elongation and acrosome formation. Am J Hum Genet 88, 351-361.
25. Henkel R, Kierspel E, Hajimohammad M, Stalf T, Hoogendijk C, Mehnert C, Menkveld R, Schill WB & Kruger TF. (2003) DNA fragmentation of spermatozoa and assisted reproduction technology. Reprod Biomed Online 7, 477-484.
26. Henkel R, Bastiaan HS, Schuller S, Hoppe I, Starker W & Menkveld R. (2010) Leucocytes and intrinsic ROS production may be factors compromising sperm chromatin condensation status. Andrologia 42, 69-75.
27. Hosseinifar H, Gourabi H, Salekdeh GH, Alikhani M, Mirshahvaladi S, Sabbaghian M, Modarresi T & Gilani MA. (2013a) Study of sperm protein profile in men with and without varicocele using two-dimensional gel electrophoresis. Urology 81, 293-300.
28. Hosseinifar H, Sabbaghian M, Chehrazi M, Modarresi T, Alipour FJ & Sadighi Gilani MA. (2013b) Assessment of deoxyribonucleic acid fragmentation index, testicular volume, semen parameters, and hormone profile in gonadotropin-treated men with hypogonadotropic hypogonadism. Urology 82, 1291-1295.
29. Hosseinifar H, Sabbaghian M, Nasrabadi D, Modarresi T, Dizaj AV, Gourabi H & Gilani MA. (2014) Study of the effect of varicocelectomy on sperm proteins expression in patients with varicocele and poor sperm quality by using two-dimensional gel electrophoresis. J Assist Reprod Genet 31, 725-729.
30. Hughes CM, Lewis SE, Mckelvey-Martin VJ & Thompson W. (1996) A comparison of baseline and induced DNA damage in human spermatozoa from fertile and infertile men, using a modified comet assay. Mol Hum Reprod 2, 613-619.
31. Irvine DS, Twigg JP, Gordon EL, Fulton N, Milne PA & Aitken RJ. (2000) DNA integrity in human spermatozoa: relationships with semen quality. J Androl 21, 33-44.
32. Koscinski I, Elinati E, Fossard C, Redin C, Muller J, Velez De La Calle J, Schmitt F, Ben Khelifa M, Ray PF, Kilani Z, Barratt CL & Viville S. (2011) DPY19L2 deletion as a major cause of globozoospermia. Am J Hum Genet 88, 344-350.
33. Kramer JA & Krawetz SA. (1997) RNA in spermatozoa: implications for the alternative haploid genome. Mol Hum Reprod 3, 473-478.
34. Kruger TF, Acosta AA, Simmons KF, Swanson RJ, Matta JF, Veeck LL, Morshedi M & Brugo S. (1987) New method of evaluating sperm morphology with predictive value for human in vitro fertilization. Urology 30, 248-251.
35. Lachaud C, Tesarik J, Canadas ML & Mendoza C. (2004) Apoptosis and necrosis in human ejaculated spermatozoa. Hum Reprod 19, 607-610.
36. Larson KL, Brannian JD, Singh NP, Burbach JA, Jost LK, Hansen KP, Kreger DO & Evenson DP. (2001) Chromatin structure in globozoospermia: a case report. J Androl 22, 424-431.
37. Menkveld R, Stander SHF, Theunis TJ, Kruger TF & Zyl JA. (1990) The evaluation of morphological characteristics of human spermatozoa according to stricter criteria. Hum Reprod 5, 586-592.
38. Morris ID. (2002) Sperm DNA damage and cancer treatment. Int J Androl 25, 255-261.
39. Palermo G, Joris H, Devroey P & Van Steirteghem AC. (1992) Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte. Lancet 340, 17-18.
40. Perreault SD, Aitken RJ, Baker HW, Evenson DP, Huszar G, Irvine DS, Morris ID, Morris RA, Robbins WA, Sakkas D, Spano M & Wyrobek AJ. (2003) Integrating new tests of sperm genetic integrity into semen analysis: breakout group discussion. Adv Exp Med Biol 518, 253-268.
41. Perrin A, Basinko A, Douet-Guilbert N, Gueganic N, Le Bris MJ, Amice V, De Braekeleer M & Morel F. (2011a) Aneuploidy and DNA fragmentation in sperm of carriers of a constitutional chromosomal abnormality. Cytogenet Genome Res 133, 100-106.
42. Perrin A, Louanjli N, Ziane Y, Louanjli T, Le Roy C, Gueganic N, Amice V, De Braekeleer M & Morel F. (2011b) Study of aneuploidy and DNA fragmentation in gametes of patients with severe teratozoospermia. Reprod Biomed Online 22, 148-154.
43. Perrin A, Coat C, Nguyen MH, Talagas M, Morel F, Amice J & De Braekeleer M. (2013) Molecular cytogenetic and genetic aspects of globozoospermia: a review. Andrologia 45, 1-9.
44. Pierre V, Martinez G, Coutton C, Delaroche J, Yassine S, Novella C, Pernet-Gallay K, Hennebicq S, Ray PF & Arnoult C. (2012) Absence of Dpy19l2, a new inner nuclear membrane protein, causes globozoospermia in mice by preventing the anchoring of the acrosome to the nucleus. Development 139, 2955-2965.
45. Potts RJ, Newbury CJ, Smith G, Notarianni LJ & Jefferies TM. (1999) Sperm chromatin damage associated with male smoking. Mutat Res 423, 103-111.
46. Sakkas D, Manicardi GC, Tomlinson M, Mandrioli M, Bizzaro D, Bianchi PG & Bianchi U. (2000) The use of two density gradient centrifugation techniques and the swim-up method to separate spermatozoa with chromatin and nuclear DNA anomalies. Hum Reprod 15, 1112-1116.
47. Saleh RA, Agarwal A, Nada EA, El-Tonsy MH, Sharma RK, Meyer A, Nelson DR & Thomas AJ. (2003a) Negative effects of increased sperm DNA damage in relation to seminal oxidative stress in men with idiopathic and male factor infertility. Fertil Steril 79(Suppl 3), 1597-1605.
48. Saleh RA, Agarwal A, Sharma RK, Said TM, Sikka SC & Thomas AJ Jr. (2003b) Evaluation of nuclear DNA damage in spermatozoa from infertile men with varicocele. Fertil Steril 80, 1431-1436.
49. Schirren CG, Holstein AF & Schirren C. (1971) Uberdie morphogenese rundkbpfiger spermatozoen des menschen. Androiogle 3, 117-125.
50. Schulte RT, Ohl DA, Sigman M & Smith GD. (2010) Sperm DNA damage in male infertility: etiologies, assays, and outcomes. J Assist Reprod Genet 27, 3-12.
51. Sermondade N, Hafhouf E, Dupont C, Bechoua S, Palacios C, Eustache F, Poncelet C, Benzacken B, Levy R & Sifer C. (2011) Successful childbirth after intracytoplasmic morphologically selected sperm injection without assisted oocyte activation in a patient with globozoospermia. Hum Reprod 26, 2944-2949.
52. Singh G. (1992) Ultrastructural features of round-headed human spermatozoa. Int J Fertil 37, 99-102.
53. Syms AJ, Johnson AR, Lipshultz LI & Smith RG. (1984) Studies on human spermatozoa with round head syndrome. Fertil Steril 42, 431-435.
54. Taylor SL, Yoon SY, Morshedi MS, Lacey DR, Jellerette T, Fissore RA & Oehninger S. (2010) Complete globozoospermia associated with PLCzeta deficiency treated with calcium ionophore and ICSI results in pregnancy. Reprod Biomed Online 20, 559-564.
55. Tejera A, Molla M, Muriel L, Remohi J, Pellicer A & De Pablo JL. (2008) Successful pregnancy and childbirth after intracytoplasmic sperm injection with calcium ionophore oocyte activation in a globozoospermic patient. Fertil Steril 90, 1202 e1-e5.
56. Vicari E, Perdichizzi A, De Palma A, Burrello N, D'agata R & Calogero AE. (2002) Globozoospermia is associated with chromatin structure abnormalities: case report. Hum Reprod 17, 2128-2133.
57. World Health Organization, WHO Laboratory Manual for the Examination of Human Semen and Sperm-cervical Mucus Interaction. (2010) 5th edn. Cambridge University Press, Cambridge.
58. Zhioua A, Merdassi G, Bhouri R, Ferfouri F, Ben Ammar A, Amouri A, Vialard F & Zhioua F. (2011) Apport del'exploration cytoge ′ ne ′ tique et ultrastructurale dans le pronostic de fertilite ′ des sujets globozoospermiques. Andrologie 21, 240-246.