Endometrial stromal fibroblasts from women with polycystic ovary syndrome have impaired progesterone-mediated decidualization, aberrant cytokine profiles and promote enhanced immune cell migration in vitro

Human Reproduction

Volumn 30, Issue 5, 2015, Pages 1203-1215

  Piltonen, T T ^a,b   Chen, J C ^a   Khatun, M ^b   Kangasniemi, M ^b   Liakka, A ^b   Spitzer, T ^a   Tran, N ^a   Huddleston, H ^a   Irwin, J C ^a   Giudice, L C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF OULU   (Finland)

Author keywords

cytokines; decidualization; endometrium; MMP; PCOS

Indexed keywords

CD14 ANTIGEN; CHEMOKINE; ESTROGEN; FRACTALKINE; GELATINASE A; GELATINASE B; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 11; INTERLEUKIN 6; INTERLEUKIN 8; INTERSTITIAL COLLAGENASE; MACROPHAGE CHEMOATTRACTANT PROTEIN 1; MACROPHAGE CHEMOATTRACTANT PROTEIN 3; MACROPHAGE ELASTASE; MATRILYSIN; PROGESTERONE; RANTES; SOMATOMEDIN BINDING PROTEIN 1; STROMELYSIN; STROMELYSIN 2; UNCLASSIFIED DRUG; CYTOKINE;

ADULT; ANALYSIS OF VARIANCE; ARTICLE; CELL COMPARTMENTALIZATION; CELL CULTURE; CELL MIGRATION; CELL MIGRATION ASSAY; CELL STRUCTURE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DECIDUALIZATION; ENDOMETRIUM CELL; FEMALE; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERANDROGENISM; IMMUNOCOMPETENT CELL; IN VITRO STUDY; LYMPHOCYTE MIGRATION; MIDDLE AGED; MONOCYTE; OVARY POLYCYSTIC DISEASE; PROTEIN EXPRESSION; PROTEIN SECRETION; REAL TIME POLYMERASE CHAIN REACTION; T LYMPHOCYTE; YOUNG ADULT; BIOPSY; CASE CONTROL STUDY; CELL MOTION; CELL PROLIFERATION; CYTOLOGY; DECIDUA; ENDOMETRIUM; ENDOMETRIUM TUMOR; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GLUCOSE TOLERANCE TEST; METABOLISM; NIDATION; PATHOLOGY; POLYCYSTIC OVARY SYNDROME; PREGNANCY; PROSPECTIVE STUDY;

ADULT; BIOPSY; CASE-CONTROL STUDIES; CELL MOVEMENT; CELL PROLIFERATION; CYTOKINES; DECIDUA; EMBRYO IMPLANTATION; ENDOMETRIAL NEOPLASMS; ENDOMETRIUM; ESTROGENS; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; GLUCOSE TOLERANCE TEST; HUMANS; MIDDLE AGED; POLYCYSTIC OVARY SYNDROME; PREGNANCY; PROGESTERONE; PROSPECTIVE STUDIES;

EID: 84929714540     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/dev055     Document Type: Article

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