Oral omega-3 fatty acids treatment in computer vision syndrome related dry eye

Contact Lens and Anterior Eye

Volumn 38, Issue 3, 2015, Pages 206-210

  Bhargava, Rahul ^a   Kumar, Prachi ^b   Phogat, Hemant ^c   Kaur, Avinash ^c   Kumar, Manjushri ^d  

^a Laser Eye Clinic   (India)

^b SANTOSH MEDICAL COLLEGE   (India)

^c Rotary Eye Hospital   (India)

^d Narayan Medical College   (India)

Author keywords

Computer vision syndrome; Dry eye; Goblet cell density; Omega 3 fatty acids (O3FAs); Tear film break up time

Indexed keywords

DOCOSAHEXAENOIC ACID; ICOSAPENTAENOIC ACID; OMEGA 3 FATTY ACID; PLACEBO;

ADULT; ARTICLE; CLINICAL ASSESSMENT TOOL; CLINICAL EVALUATION; COMPUTER VISION SYNDROME RELATED DRY EYE; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG HYPERSENSITIVITY; DRUG WITHDRAWAL; DRY EYE; EYE EXAMINATION; FEMALE; FOLLOW UP; GASTROINTESTINAL SYMPTOM; HUMAN; HUMAN CELL; HUMAN TISSUE; IMPRESSION CYTOLOGY; INTERVENTION STUDY; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NELSON GRADE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SCHIRMER TEST; SCORING SYSTEM; SYMPTOMATOLOGY; TEAR FILM; TEAR FILM BREAK UP TIME; TREATMENT DURATION; VISUAL ACUITY; VISUAL SYSTEM PARAMETERS; CLINICAL TRIAL; COMPUTER; DOSE RESPONSE; DRY EYE SYNDROMES; LACRIMAL FLUID; METABOLISM; ORAL DRUG ADMINISTRATION; PILOT STUDY; PROSPECTIVE STUDY; SYNDROME; TREATMENT OUTCOME; YOUNG ADULT;

ADMINISTRATION, ORAL; COMPUTERS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DRY EYE SYNDROMES; FATTY ACIDS, OMEGA-3; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; PILOT PROJECTS; PROSPECTIVE STUDIES; SYNDROME; TEARS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84929706567     PISSN: 13670484     EISSN: 14765411     Source Type: Journal    
DOI: 10.1016/j.clae.2015.01.007     Document Type: Article

References (27)

1. The definition and classification of dry eye disease: report of the Definition and Classification Subcommittee of the International Dry Eye Workshop (2007). Ocul Surf 2007, 5(2):75-92.
2. The epidemiology of dry eye disease: report of the Epidemiology Subcommittee of the International Dry Eye Workshop (2007). Ocul Surf 2007, 5(2):93-107.
3. Schaumberg D.A., Buring J.E., Sullivan D.A., Dana M.R. Hormone replacement therapy and dry eye syndrome. JAMA 2001, 286(17):2114-2119.
4. Ang R.T., Dartt D.A., Tsubota K. Dry eye after refractive surgery. Curr Opin Ophthalmol 2001, 12(4):318-322.
5. Donnenfeld E.D., Ehrenhaus M., Solomon R., Mazurek J., Rozell J.C., Perry H.D. Effect of hinge width on corneal sensation and dry eye after laser in situ keratomileusis. J Cataract Refract Surg 2004, 30(4):790-797.
6. Cardona G., García C., Serés C., Vilaseca M., Gispets J. Blink rate, blink amplitude, and tear film integrity during dynamic visual display terminal tasks. Curr Eye Res 2011, 36(3):190-197.
7. Schlote T., Kadner G., Freudenthaler N. Marked reduction and distinct patterns of eye blinking in patients with moderately dry eyes during video display terminal use. Graefes Arch Clin Exp Ophthalmol 2004, 242(4):306-312.
8. Lee A.J., Lee J., Saw S.M., Gazzard G., Koh D., Widjaja D., et al. Prevalence and risk factors associated with dry eye symptoms: a population based study in Indonesia. Br J Ophthalmol 2002, 86(12):1347-1351.
9. Perry H.D. Dry eye disease: pathophysiology, classification, and diagnosis. Am J Manag Care 2008, 14:S79-S87.
10. Rosenfield M. Computer vision syndrome: a review of ocular causes and potential treatments. Ophthalmic Physiol Opt 2011, 31(5):502-515.
11. Huang F.C., Tseng S.H., Shih M.H., Chen F.K. Effect of artificial tears on corneal surface regularity, contrast sensitivity, and glare disability in dry eyes. Ophthalmology 2002, 109(10):1934-1940.
12. Management and therapy of dry eye disease: report of the Management and Therapy Subcommittee of the International Dry Eye Work Shop. Ocul Surf 2007, 5(2):163-178.
13. Nelson J.D., Farris R.L. Sodium hyaluronate and polyvinyl alcohol artificial tear preparations. A comparison in patients with keratoconjunctivitis sicca. Arch Ophthalmol 1988, 106(4):484-487.
14. Roncone M., Bartlett H., Eperjesi F. Essential fatty acids for dry eye: a review. Cont Lens Anterior Eye 2010, 33(2):49-54.
15. Wojtowicz J.C., Butovich I., Uchiyama E., Aronowicz J., Agee S., McCulley J.P. Pilot, prospective, randomized, double-masked, placebo-controlled clinical trial of an omega-3 supplement for dry eye. Cornea 2011, 30(3):308-314.
16. Miljanović B., Trivedi K.A., Dana M.R., Gilbard J.P., Buring J.E., Schaumberg D.A. Relation between dietary n-3 and n-6 fatty acids and clinically diagnosed dry eye syndrome in women. Am J Clin Nutr 2005, 82(4):887-893.
17. Kumar P., Bhargava R., Kumar M., Ranjan S., Kumar M., Verma P. The correlation of routine tear function tests and conjunctival impression cytology in dry eye syndrome. Korean J Ophthalmol 2014, 28(2):122-129.
18. Doughty M.J. Sampling area selection for the assessment of goblet cell density from conjunctival impression cytology specimens. Eye Contact Lens 2012, 38:122-129.
19. Nelson J.D., Havener V.R., Cameron J.D. Cellulose acetate impressions of the ocular surface. Dry eye states. Arch Ophthalmol 1983, 101(12):1869-1872.
20. Jakhar K.A., Pal A.K., Reddy D.A., Sahu N.P., Venkateshwarlu G., Vardia H.K. Fatty Acids composition of some selected Indian fishes. Afr J Basic Appl Sci 2012, 4:155-160.
21. Uchino M., Schaumberg D.A., Dogru M., Uchino Y., Fukagawa K., Shimmura S., et al. Prevalence of dry eye disease among Japanese visual display terminal users. Ophthalmology 2008, 115(11):1982-1988.
22. Unlü C., Güney E., Akçay B.I., Akçali G., Erdoğan G., Bayramlar H. Comparison of ocular-surface disease index questionnaire, tear film break-up time, and Schirmer tests for the evaluation of the tear film in computer users with and without dry-eye symptomatology. Clin Ophthalmol 2012, 6:1303-1306.
23. Nichols K.K., Nichols J.J., Mitchell G.L. The lack of association between signs and symptoms in patients with dry eye disease. Cornea 2004, 23(8):762-770.
24. Schaumberg D.A., Sullivan D.A., Buring J.E., Dana M.R. Prevalence of dry eye syndrome among US women. Am J Ophthalmol 2003, 136(2):318-326.
25. Kangari H., Eftekhari M.H., Sardari S., Hashemi H., Salamzadeh J., Ghassemi-Broumand M., et al. Short-term consumption of oral omega-3 and dry eye syndrome. Ophthalmology 2013, 120(11):2191-2196.
26. Bhargava R., Kumar P., Kumar M., Mehra N., Mishra A. A randomized controlled trial of omega-3 fatty acids in dry eye syndrome. Int J Ophthalmol 2013, 6(6):811-816.
27. Brignole-Baudouin F., Baudouin C., Aragona P., Rolando M., Labetoulle M., Pisella P.J., et al. A multicentre, double-masked, randomized, controlled trial assessing the effect of oral supplementation of omega-3 and omega-6 fatty acids on a conjunctival inflammatory marker in dry eye patients. Acta Ophthalmol 2011, 89(7):e591-e597.