The contribution of raised intraneuronal chloride to epileptic network activity

Journal of Neuroscience

Volumn 35, Issue 20, 2015, Pages 7715-7726

  Alfonsa, Hannah ^a   Merricks, Edward M ^a   Codadu, Neela K ^a   Cunningham, Mark O ^a   Deisseroth, Karl ^b,c   Racca, Claudia ^a   Trevelyan, Andrew J ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b Stanford University   (United States)

^c STANFORD UNIVERSITY   (United States)

Author keywords

Chloride; Fast spiking interneuron; High frequency oscillations; Neocortex; Pyramidal neuron; Seizure

Indexed keywords

CHLORIDE ION; HALORHODOPSIN; 4 AMINOBUTYRIC ACID RECEPTOR; CHLORIDE; FAMPRIDINE; POTASSIUM CHANNEL BLOCKING AGENT;

ACTION POTENTIAL; ADULT; AMPLITUDE MODULATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPUTER MODEL; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ELECTROSTIMULATION; EPILEPSY; EXCITATORY POSTSYNAPTIC POTENTIAL; FREQUENCY ANALYSIS; ILLUMINATION; IMMUNOCYTOCHEMISTRY; LATENT PERIOD; MALE; MOUSE; NERVE CELL EXCITABILITY; NERVE CELL NETWORK; NERVE CONDUCTION; NONHUMAN; OPTOGENETICS; PATCH CLAMP TECHNIQUE; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SYNAPTIC TRANSMISSION; WHITE MATTER; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; EXTRACELLULAR SPACE; METABOLISM; NEOCORTEX; PATHOPHYSIOLOGY; PHYSIOLOGY;

4-AMINOPYRIDINE; ACTION POTENTIALS; ANIMALS; CELLS, CULTURED; CHLORIDES; EPILEPSY; EXTRACELLULAR SPACE; GABAERGIC NEURONS; HALORHODOPSINS; MICE; NEOCORTEX; POTASSIUM CHANNEL BLOCKERS; PYRAMIDAL CELLS; RATS;

EID: 84929688858     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4105-14.2015     Document Type: Article

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