Therapeutic envelope vaccination in combination with antiretroviral therapy temporarily rescues SIV-specific CD4+ T-cell-dependent natural killer cell effector responses in chronically infected rhesus macaques

Immunology

Volumn 145, Issue 2, 2015, Pages 288-299

  Vargas Inchaustegui, Diego A ^a   Xiao, Peng ^a,c   Demberg, Thorsten ^a   Pal, Ranajit ^b   Robert Guroff, Marjorie ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b ADVANCED BIOSCIENCE LABORATORIES INC   (United States)

^c EMORY UNIVERSITY   (United States)

Author keywords

Antiretroviral therapy; Envelope immunization; Natural killer cells; T cells

Indexed keywords

ALUMINUM HYDROXIDE; CD56 ANTIGEN; DIDANOSINE; GAMMA INTERFERON; INTERLEUKIN 2; PHOSPHORYL LIPID A; RECOMBINANT GLYCOPROTEIN GP 120; STAVUDINE; TENOFOVIR; TUMOR NECROSIS FACTOR ALPHA; VIRUS ENVELOPE PROTEIN;

ADJUVANT THERAPY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL THERAPY; ARTICLE; CD4+ T LYMPHOCYTE; CELLULAR IMMUNITY; CHRONOTHERAPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFICACY; EFFECTOR CELL; IMMUNE RESPONSE; IMMUNOGENICITY; INFECTION PREVENTION; MONOTHERAPY; MUCOSA; NATURAL KILLER CELL; NONHUMAN; PLASMA; PRIORITY JOURNAL; REBOUND; RHESUS MONKEY; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; SINGLE DRUG DOSE; T LYMPHOCYTE ACTIVATION; VACCINATION; VIRUS ENVELOPE; VIRUS LOAD; ANIMAL; CD4 LYMPHOCYTE COUNT; DRUG EFFECTS; FEMALE; IMMUNOLOGY; MALE; PATHOLOGY; TIME;

ANIMALS; CD4 LYMPHOCYTE COUNT; CD4-POSITIVE T-LYMPHOCYTES; FEMALE; GENE PRODUCTS, ENV; IMMUNITY, CELLULAR; KILLER CELLS, NATURAL; MACACA MULATTA; MALE; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA; VACCINATION;

EID: 84929658069     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12447     Document Type: Article

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