Klebsiella pneumoniae-triggered DC recruit human NK cells in a CCR5-dependent manner leading to increased CCL19-responsiveness and activation of NK cells

European Journal of Immunology

Volumn 40, Issue 11, 2010, Pages 3138-3149

  Van Elssen, Catharina H M J ^a,b   Vanderlocht, Joris ^a   Frings, Peter W H ^a   Senden Gijsbers, Birgit L M G ^a   Schnijderberg, Melanie C A ^a   van Gelder, Michel ^a   Meek, Bob ^a   Libon, Christine ^c   Ferlazzo, Guido ^d   Germeraad, Wilfred T V ^a   Bos, Gerard M J ^a  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b PharmaCell BV   (Netherlands)

^c INSTITUT DE RECHERCHE PIERRE FABRE   (France)

^d UNIVERSITY OF MESSINA   (Italy)

Author keywords

CCR5; CCR7; NK DC interaction; Th1 polarization

Indexed keywords

CD16 ANTIGEN; CD56 ANTIGEN; CHEMOKINE RECEPTOR CCR5; GAMMA INTERFERON; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; CCL19 PROTEIN, HUMAN; CCR7 PROTEIN, HUMAN; CHEMOKINE RECEPTOR CCR7; TLR2 PROTEIN, HUMAN; TLR4 PROTEIN, HUMAN;

ARTICLE; BACTERIAL MEMBRANE; CELL ACTIVATION; CELL MATURATION; CELL MIGRATION; CYTOKINE PRODUCTION; CYTOTOXICITY; DENDRITIC CELL; HUMAN; HUMAN CELL; KLEBSIELLA PNEUMONIAE; LYMPH NODE; NATURAL KILLER CELL; NATURAL KILLER CELL ACTIVATION; NORMAL HUMAN; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; TH1 CELL; CELL CULTURE; CELL MOTION; GENE EXPRESSION REGULATION; IMMUNOLOGY; KLEBSIELLA INFECTION; LYMPHOCYTE ACTIVATION;

CELL MOVEMENT; CELLS, CULTURED; CHEMOKINE CCL19; DENDRITIC CELLS; GENE EXPRESSION REGULATION; HUMANS; INTERFERON-GAMMA; KILLER CELLS, NATURAL; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; LYMPHOCYTE ACTIVATION; RECEPTORS, CCR5; RECEPTORS, CCR7; TH1 CELLS; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

EID: 79952109950     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201040496     Document Type: Article

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