Immunological, viral, environmental, and individual factors modulating lung immune response to respiratory syncytial virus

BioMed Research International

Volumn 2015, Issue , 2015, Pages

  Vandini, Silvia ^a   Bottau, Paolo ^b   Faldella, Giacomo ^a   Lanari, Marcello ^b  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b Imola Hospital   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

HOST FACTOR;

ARTICLE; ENVIRONMENTAL FACTOR; HIGH RISK INFANT; HUMAN; HUMAN RESPIRATORY SYNCYTIAL VIRUS; IMMUNE RESPONSE; IMMUNOMODULATION; LETHALITY; NONHUMAN; PATHOGENESIS; RESPIRATORY SYNCYTIAL VIRUS INFECTION; RESPIRATORY TRACT INFECTION; RISK FACTOR; IMMUNOLOGY; INNATE IMMUNITY; ISOLATION AND PURIFICATION; LUNG; PATHOGENICITY; PATHOLOGY; VIROLOGY;

ANIMALIA; RESPIRATORY SYNCYTIAL VIRUS;

HUMANS; IMMUNITY, INNATE; LUNG; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUSES; RESPIRATORY TRACT INFECTIONS;

EID: 84929646310     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2015/875723     Document Type: Article

References (75)

1. C. B. Hall, G. A. Weinberg, M. K. Iwane et al., "The Burden of respiratory syncytial virus infection in young children, " The New England Journal of Medicine, vol. 360, no. 6, pp. 588-598, 2009.
2. H. Nair, V. R. Verma, E. Theodoratou et al., "An evaluation of the emerging interventions against Respiratory Syncytial Virus (RSV)-associated acute lower respiratory infections in children, " BMC Public Health, vol. 11, supplement 3, article S30, 2011.
3. W. W. Thompson, D. K. Shay, E. Weintraub et al., "Mortality associated with influenza and respiratory syncytial virus in the United States, " Journal of theAmericanMedical Association, vol. 289, no. 2, pp. 179-186, 2003.
4. B. C. Hall, J. M. Geiman, R. G. Douglas Jr., and M. P. Meagher, "Control of nosocomial respiratory syncytial viral infections, " Pediatrics, vol. 62, no. 5, pp. 728-732, 1978.
5. L. C. Paramore, V. Ciuryla, G. Ciesla, and L. Liu, "Economic impact of respiratory syncytial virus-related illness in the US: an analysis of national databases, " PharmacoEconomics, vol. 22, no. 5, pp. 275-284, 2004.
6. A. R. Falsey, "Respiratory syncytial virus infection in elderly and high-risk adults, " Experimental Lung Research, vol. 31, supplement 1, p. 77, 2005.
7. J. E. Johnson, R. A. Gonzales, S. J. Olson, P. F. Wright, and B. S. Graham, "The histopathology of fatal untreated human respiratory syncytial virus infection, " Modern Pathology, vol. 20, no. 1, pp. 108-119, 2007.
8. T. P. Welliver, J. L. Reed, and R. C. Welliver Jr., "Respiratory syncytial virus and influenza virus infections observations from tissues of fatal infant cases, " Pediatric Infectious Disease Journal, vol. 27, no. 10, supplement, pp. S92-S96, 2008.
9. R. A. Bem, J. B. Domachowske, and H. F. Rosenberg, "Animal models of human respiratory syncytial virus disease, " The American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 301, no. 2, pp. L148-L156, 2011.
10. S. A. Cormier, D. You, and S. Honnegowda, "The use of a neonatal mouse model to study respiratory syncytial virus infections, " Expert Review of Anti-Infective Therapy, vol. 8, no. 12, pp. 1371-1380, 2010.
11. L. Tasker, R. W. B. Lindsay, B. T. Clarke, D. W. R. Cochrane, and S. Hou, "Infection of mice with respiratory syncytial virus during neonatal life primes for enhanced antibody and T cell responses on secondary challenge, " Clinical & Experimental Immunology, vol. 153, no. 2, pp. 277-288, 2008.
12. B. S. Graham, L. A. Bunton, J. Rowland, P. F. Wright, and D. T. Karzon, "Respiratory syncytial virus infection in anti-treated mice, " Journal of Virology, vol. 65, no. 9, pp. 4936-4942, 1991.
13. R. J. Derscheid andM. R. Ackermann, "Perinatal lamb model of respiratory syncytial virus (RSV) infection, " Viruses, vol. 4, no. 10, pp. 2359-2378, 2012.
14. S. van Drunen Littel-van den Hurk and E. R. Watkiss, "Pathogenesis of respiratory syncytial virus, " Current Opinion in Virology, vol. 2, no. 3, pp. 300-305, 2012.
15. F. B. Sow, J. M. Gallup, S. Krishnan, A. C. Patera, J. Suzich, and M. R. Ackermann, "Respiratory syncytial virus infection is associated with an altered innate immunity and a heightened pro-inflammatory response in the lungs of preterm lambs, " Respiratory Research, vol. 12, article 106, 2011.
16. C. J. Clarke, N. J. Watt, A. Meredith, N. McIntyre, and S. M. Burns, "Respiratory syncytial virus-associated bronchopneumonia in a young chimpanzee, " Journal of Comparative Pathology, vol. 110, no. 2, pp. 207-212, 1994.
17. R. B. Belshe, L. S. Richardson, W. T. London et al., "Experimental respiratory syncytial virus infection of four species of primates, " Journal of Medical Virology, vol. 1, no. 3, pp. 157-162, 1977.
18. G. A. Prince, V. G. Hemming, R. L. Horswood, P. A. Baron, and R. M. Chanock, "Effectiveness of topically administered neutralizing antibodies in experimental immunotherapy of respiratory syncytial virus infection in cotton rats, " Journal of Virology, vol. 61, no. 6, pp. 1851-1854, 1987.
19. M. S. Boukhvalova, G. A. Prince, and J. C. G. Blanco, "The cotton ratmodel of respiratory viral infections, " Biologicals, vol. 37, no. 3, pp. 152-159, 2009.
20. S. Niewiesk andG. Prince, "Diversifying animal models: the use of hispid cotton rats (Sigmodon hispidus) in infectious diseases, " Laboratory Animals, vol. 36, no. 4, pp. 357-372, 2002.
21. J. Mestas and C. C. W. Hughes, "Of mice and not men: differences between mouse and human immunology, " Journal of Immunology, vol. 172, no. 5, pp. 2731-2738, 2004.
22. C. G. Irvin and J. H. T. Bates, "Measuring the lung function in the mouse: the challenge of size, " Respiratory Research, vol. 4, article 4, 2003.
23. M. F. Paccaud and C. Jacquier, "A respiratory syncytial virus of bovine origin, " Archiv für die Gesamte Virusforschung, vol. 30, no. 4, pp. 327-342, 1970.
24. C. A. Bonville, N. J. Bennett, M. Koehnlein et al., "Respiratory dysfunction and proinflammatory chemokines in the pneumonia virus of mice (PVM) model of viral bronchiolitis, " Virology, vol. 349, no. 1, pp. 87-95, 2006.
25. P. A. González, S. M. Bueno, L. J. Carreño, C. A. Riedel, and A. M. Kalergis, "Respiratory syncytial virus infection and immunity, " Reviews in Medical Virology, vol. 22, no. 4, pp. 230-244, 2012.
26. R. M. Liesman, U. J. Buchholz, C. L. Luongo et al., "RSVencoded NS2 promotes epithelial cell shedding and distal airway obstruction, " The Journal of Clinical Investigation, vol. 124, no. 5, pp. 2219-2233, 2014.
27. P. L. Collins and J. E. J. Crowe, "Respiratory syncytial virus and metapneumovirus, " in Fields Virology, D. M. Knipe, P. M. Howley, D. E. Griffin et al., Eds., pp. 1601-1646, Lippincott Williams &Wilkins, Philadelphia, Pa, USA, 5th edition, 2007.
28. P. L. Collins and B. S. Graham, "Viral and host factors in human respiratory syncytial virus pathogenesis, " Journal of Virology, vol. 82, no. 5, pp. 2040-2055, 2008.
29. J. A. Melero, B. Garć a-Barreno, I. Martńez, C. R. Pringle, and P. A. Cane, "Antigenic structure, evolution and immunobiology of human respiratory syncytial virus attachment (G) protein, " Journal of General Virology, vol. 78, no. 10, pp. 2411-2418, 1997.
30. A. Bukreyev, L. Yang, J. Fricke et al., "The secreted form of respiratory syncytial virus G glycoprotein helps the virus evade antibody-mediated restriction of replication by acting as an antigen decoy and through effects on Fc receptor-bearing leukocytes, " Journal of Virology, vol. 82, no. 24, pp. 12191-12204, 2008.
31. R. A. Tripp, S. Hou, N. Etchart et al., "CD4+ T cell frequencies and Th1/Th2 cytokine patterns expressed in the acute and memory response to respiratory syncytial virus I-E-restricted peptides, " Cellular Immunology, vol. 207, no. 1, pp. 59-71, 2001.
32. A. M. Cepika, A. Gagro, A. Bace et al., "Expression of chemokine receptor CX3CR1 in infants with respiratory syncytial virus bronchiolitis, " Pediatric Allergy and Immunology, vol. 19, no. 2, pp. 148-156, 2008.
33. F. P. Polack, P. M. Irusta, S. J. Hoffman et al., "The cysteinerich region of respiratory syncytial virus attachment protein inhibits innate immunity elicited by the virus and endotoxin, " Proceedings of the National Academy of Sciences of the United States of America, vol. 102, no. 25, pp. 8996-9001, 2005.
34. J. Figueras-Aloy, X. Carbonell-Estrany, and J. Quero, "Casecontrol study of the risk factors linked to respiratory syncytial virus infection requiring hospitalization in premature infants born at a gestational age of 33-35 weeks in Spain, " Pediatric Infectious Disease Journal, vol. 23, no. 9, pp. 815-820, 2004.
35. E. E. L. Wang, B. J. Law, andD. Stephens, "Pediatric Investigators Collaborative Network on Infections in Canada (PICNIC) prospective study of risk factors and outcomes in patients hospitalized with respiratory syncytial viral lower respiratory tract infection, " The Journal of Pediatrics, vol. 126, no. 2, pp. 212-219, 1995.
36. M. Lanari, F. Prinelli, F. Adorni et al., "Maternal milk protects infants against bronchiolitis during the first year of life: results from an Italian cohort of newborns, " Early Human Development, vol. 89, no. 1, pp. S51-S57, 2013.
37. R. Welliver, "The relationship of meteorological conditions to the epidemic activity of respiratory syncytial virus, " Paediatric Respiratory Reviews, vol. 10, supplement 1, pp. 6-8, 2009.
38. M. Lanari, F. Adorni, M. Silvestri, A. Coscia, and M. Musicco, "The multicenter Italian birth cohort study on incidence and determinants of lower respiratory tract infection hospitalization in infants at 33weeks GA or more: preliminary results, " Early Human Development, vol. 87, no. 1, pp. S43-S46, 2011.
39. M. E. Belderbos, M. L. Houben, B. Wilbrink et al., "Cord blood vitamin D deficiency is associated with respiratory syncytial virus bronchiolitis, " Pediatrics, vol. 127, no. 6, pp. e1513-e1520, 2011.
40. M. Lanari, S. Vandini, M. G. Capretti, T. Lazzarotto, and G. Faldella, "Respiratory syncytial virus infections in infants affected by primary immunodeficiency, " Journal of Immunology Research, vol. 2014, Article ID 850831, 6 pages, 2014.
41. T. L. Noah and S. Becker, "Respiratory syncytial virus-induced cytokine production by a human bronchial epithelial cell line, " The American Journal of Physiology, vol. 265, no. 5, pp. L472-L478, 1993.
42. D. A. Tristram, W. Hicks Jr., and R. Hard, "Respiratory syncytial virus and human bronchial epithelium, " Archives of Otolaryngology: Head & Neck Surgery, vol. 124, no. 7, pp. 777-783, 1998.
43. J. A. Patel, M. Kunimoto, T. C. Sim et al., "Interleukin-1 alpha mediates the enhanced expression of intercellular adhesion molecule-1 in pulmonary epithelial cells infected with respiratory syncytial virus, "The American Journal of Respiratory Cell and Molecular Biology, vol. 13, no. 5, pp. 602-609, 1995.
44. L. Bont and J. L. L. Kimpen, "Immunological mechanisms of severe respiratory syncytial virus bronchiolitis, " Intensive Care Medicine, vol. 28, no. 5, pp. 616-621, 2002.
45. T. H. Kim and H. K. Lee, "Innate immune recognition of respiratory syncytial virus infection, " BMB Reports, vol. 47, no. 4, pp. 184-191, 2014.
46. J. A. Espinoza, K. Bohmwald, P. F. Céspedes, C. A. Riedel, S. M. Bueno, and A. M. Kalergis, "Modulation of host adaptive immunity by hRSV proteins, " Virulence, vol. 5, no. 7, pp. 740-751, 2014.
47. B. R. Murphy, "Mucosal immunity to viruses, " in Mucosal Immunity, J. E. A. Mestecky, Ed., Elsevier Academic Press, Amsterdam, The Netherlands, 2005.
48. G. R. Siber, D. Leombruno, J. Leszczynski et al., "Comparison of antibody concentrations and protective activity of respiratory syncytial virus immune globulin and conventional immune globulin, " Journal of Infectious Diseases, vol. 169, no. 6, pp. 1368-1373, 1994.
49. A. R. Falsey, E. E. Walsh, R. J. Looney et al., "Comparison of respiratory syncytial virus humoral immunity and response to infection in young and elderly adults, " Journal of Medical Virology, vol. 59, no. 2, pp. 221-226, 1999.
50. P. S. McNamara, B. F. Flanagan, C. A. Hart, and R. L. Smyth, "Production of chemokines in the lungs of infants with severe respiratory syncytial virus bronchiolitis, " The Journal of Infectious Diseases, vol. 191, no. 8, pp. 1225-1232, 2005.
51. E. R. Barreira, A. R. Precioso, and A. Bousso, "Pulmonary surfactant in respiratory syncytial virus bronchiolitis: the role in pathogenesis and clinical implications, " Pediatric Pulmonology, vol. 46, no. 5, pp. 415-420, 2011.
52. P. F. Wright, M. R. Ikizler, R. A. Gonzales, K. N. Carroll, J. E. Johnson, and J. A. Werkhaven, "Growth of respiratory syncytial virus in primary epithelial cells from the human respiratory tract, " Journal of Virology, vol. 79, no. 13, pp. 8651-8654, 2005.
53. I. Miyairi and J. P. DeVincenzo, "Human genetic factors and respiratory syncytial virus disease severity, " Clinical Microbiology Reviews, vol. 21, no. 4, pp. 686-703, 2008.
54. S. Vandini, L. Corvaglia, R. Alessandroni et al., "Respiratory syncytial virus infection in infants and correlation with meteorological factors and air pollutants, " Italian Journal of Pediatrics, vol. 39, no. 1, article 1, 2013.
55. M. L. Everard, A. Swarbrick, M. Wrightham et al., "Analysis of cells obtained by bronchial lavage of infants with respiratory syncytial virus infection, " Archives of Disease in Childhood, vol. 71, no. 5, pp. 428-432, 1994.
56. M. Abu-Harb, F. Bell, A. Finn et al., "IL-8 and neutrophil elastase levels in the respiratory tract of infants with RSV bronchiolitis, " European Respiratory Journal, vol. 14, no. 1, pp. 139-143, 1999.
57. W. Aherne, T. Bird, S. D. Court, P. S. Gardner, and J. McQuillin, "Pathological changes in virus infections of the lower respiratory tract in children, " Journal of Clinical Pathology, vol. 23, no. 1, pp. 7-18, 1970.
58. R. Garofalo, J. L. L. Kimpen, R. C. Welliver, and P. L. Ogra, "Eosinophil degranulation in the respiratory tract during naturally acquired respiratory syncytial virus infection, " The Journal of Pediatrics, vol. 120, no. 1, pp. 28-32, 1992.
59. S. M. Varga andT. J. Braciale, "The adaptive immune response to respiratory syncytial virus, " Current Topics in Microbiology and Immunology, vol. 372, pp. 155-171, 2013.
60. D. S. McDermott, K. A. Weiss, C. J. Knudson, and S. M. Varga, "Central role of dendritic cells in shaping the adaptive immune response during respiratory syncytial virus infection, " Future Virology, vol. 6, no. 8, pp. 963-973, 2011.
61. W. deWeerd, W. N. Twilhaar, and J. L. L. Kimpen, "T cell subset analysis in peripheral blood of children with RSV bronchiolitis, " Scandinavian Journal of InfectiousDiseases, vol. 30, no. 1, pp. 77-80, 1998.
62. J. H. Aberle, S. W. Aberle, M. N. Dworzak et al., "Reduced interferon-expression in peripheral blood mononuclear cells of infants with severe respiratory syncytial virus disease, " The American Journal of Respiratory and Critical CareMedicine, vol. 160, no. 4, pp. 1263-1268, 1999.
63. L. Bont, C. J. Heijnen, A. Kavelaars et al., "Peripheral blood cytokine responses and disease severity in respiratory syncytial virus bronchiolitis, " European Respiratory Journal, vol. 14, no. 1, pp. 144-149, 1999.
64. R. B. Fulton, D. K. Meyerholz, and S. M. Varga, "Foxp3+ CD4 regulatory T cells limit pulmonary immunopathology by modulating the CD8 T cell response during respiratory syncytial virus infection, " Journal of Immunology, vol. 185, no. 4, pp. 2382-2392, 2010.
65. S. Munir, P. Hillyer, C. le Nouën et al., "Respiratory syncytial virus interferon antagonist NS1 protein suppresses and skews the human T lymphocyte response, " PLoS Pathogens, vol. 7, no. 4, Article ID e1001336, 2011.
66. C. le Nouën, P. Hillyer, C. C. Winter et al., "Low CCR7-mediated migration of humanmonocyte derived dendritic cells in response to human respiratory syncytial virus and human metapneumovirus, " PLoS Pathogens, vol. 7, no. 6, Article ID e1002105, 2011.
67. F. E.-H. Lee, A. R. Falsey, J. L. Halliley, I. Sanz, and E. E. Walsh, "Circulating antibody-secreting cells during acute respiratory syncytial virus infection in adults, " Journal of InfectiousDiseases, vol. 202, no. 11, pp. 1659-1666, 2010.
68. M. Goritzka, L. R. Durant, C. Pereira, S. Salek-Ardakani, P. J. M. Openshaw, and C. Johansson, "Alpha/beta interferon receptor signaling amplifies early proinflammatory cytokine production in the lung during respiratory syncytial virus infection, " Journal of Virology, vol. 88, no. 11, pp. 6128-6136, 2014.
69. M. A. Schijf, M. V. Lukens, D. Kruijsen et al., "Respiratory syncytial virus induced type I IFN production by pDC is regulated by RSV-infected airway epithelial cells, RSV-exposed monocytes and virus specific antibodies, " PLoS ONE, vol. 8, no. 11, Article ID e81695, 2013.
70. J. Chin, R. L. Magoffin, L. A. Shearer, J. H. Schieble, and E. H. Lennette, "Field evaluation of a respiratory syncytial virus vaccine and a trivalent parainfluenza virus vaccine in a pediatric population, " The American Journal of Epidemiology, vol. 89, no. 4, pp. 449-463, 1969.
71. E. M. Castilow and S. M. Varga, "Overcoming T-cell-mediated immunopathology to achieve safe respiratory syncytial virus vaccination, " Future Virology, vol. 3, no. 5, pp. 445-454, 2008.
72. A. Z. Kapikian, R. H. Mitchell, R. M. Chanock, R. A. Shvedoff, and C. E. Stewart, "An epidemiologic study of altered clinical reactivity to Respiratory Syncytial (RS) virus infection in children previously vaccinated with an inactivated RS virus vaccine, " American Journal of Epidemiology, vol. 89, no. 4, pp. 405-421, 1969.
73. Y. Murata, "Respiratory syncytial virus vaccine development, " Clinics in LaboratoryMedicine, vol. 29, no. 4, pp. 725-739, 2009.
74. P. A. Piedra, A. M. Jewell, S. G. Cron, R. L. Atmar, andW. P. Glezen, "Correlates of immunity to respiratory syncytial virus (RSV) associated-hospitalization: establishment of minimum protective threshold levels of serum neutralizing antibodies, " Vaccine, vol. 21, no. 24, pp. 3479-3482, 2003.
75. F. D. Martinez, "Respiratory syncytial virus bronchiolitis and the pathogenesis of childhood asthma, " Pediatric Infectious Disease Journal, vol. 22, no. 2, supplement, pp. S76-S82, 2003.