Nervous System Lyme Disease

Infectious Disease Clinics of North America

Volumn 29, Issue 2, 2015, Pages 241-253

  Halperin, John J ^a,b  

^a Overlook Medical Center   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Borrelia burgdorferi; Central nervous system; Garin Bujadoux Bannwarth syndrome; Intrathecal antibody; Lyme disease; Nervous system; Neuroborreliosis; Peripheral nervous system

Indexed keywords

ANTIBODY; BORRELIA BURGDORFERI ANTIBODY; CEFTRIAXONE; DOXYCYCLINE; PENICILLIN DERIVATIVE; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT;

ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ARTICLE; BEHAVIOR CHANGE; BORRELIA AFZELII; BORRELIA BURGDORFERI; BORRELIA GARINII; CENTRAL NERVOUS SYSTEM INFECTION; CEREBROSPINAL FLUID CULTURE; COMPUTER ASSISTED TOMOGRAPHY; CRANIAL NEURITIS; CRANIAL NEUROPATHY; DISEASE ASSOCIATION; DISEASE SEVERITY; DRUG EFFICACY; DRUG MEGADOSE; DRUG RESPONSE; FACIAL NERVE PARALYSIS; HISTORY OF MEDICINE; HUMAN; IXODES; LYME DISEASE; LYME ENCEPHALOPATHY; LYME MENINGITIS; MENINGITIS; NEURITIS; NEUROBORRELIOSIS; NEUROLOGIC DISEASE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PLEOCYTOSIS; POLYRADICULONEUROPATHY; PREVALENCE; SEROLOGY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SUBARACHNOID SPACE; COGNITION DISORDERS; DIFFERENTIAL DIAGNOSIS; ISOLATION AND PURIFICATION; LYME NEUROBORRELIOSIS; MEMORY DISORDERS; MICROBIOLOGY;

ANTI-BACTERIAL AGENTS; BORRELIA BURGDORFERI; COGNITION DISORDERS; DIAGNOSIS, DIFFERENTIAL; HUMANS; LYME NEUROBORRELIOSIS; MEMORY DISORDERS;

EID: 84929610358     PISSN: 08915520     EISSN: 15579824     Source Type: Journal    
DOI: 10.1016/j.idc.2015.02.002     Document Type: Review

References (33)

1. Halperin J.J., Baker P., Wormser G.P. Common misconceptions about Lyme disease. Am J Med 2013, 126:264.e1-264.e7.
2. Halperin J.J. Lyme disease - neurology, neurobiology and behavior. Clin Infect Dis 2014, 58:1267-1272.
3. Steere A.C., Pachner A.R., Malawista S.E. Neurologic abnormalities of Lyme disease: successful treatment with high-dose intravenous penicillin. Ann Intern Med 1983, 99:767-772.
4. Reik L., Steere A.C., Bartenhagen N.H., et al. Neurologic abnormalities of Lyme disease. Medicine 1979, 58:281-294.
5. Garin C., Bujadoux A. Paralysie par les tiques. JMed Lyon 1922, 71:765-767.
6. Hollstrom E. Successful treatment of erythema migrans Afzelius. Acta Derm Venereol 1951, 31:235-243.
7. Halperin J., Logigian E., Finkel M., et al. Practice parameter for the diagnosis of patients with nervous system Lyme borreliosis (Lyme disease). Neurology 1996, 46:619-627.
8. Mygland A., Ljostad U., Fingerle V., et al. EFNS guidelines on the diagnosis and management of European Lyme neuroborreliosis. Eur J Neurol 2010, 17:8-16. e1-4.
9. Ogrinc K., Lotric-Furlan S., Maraspin V., et al. Suspected early Lyme neuroborreliosis in patients with erythema migrans. Clin Infect Dis 2013, 57:501-509.
10. Bacon R.M., Kugeler K.J., Mead P.S. Surveillance for Lyme Disease - United States, 1992-2006. MMWR Morb Mortal Wkly Rep 2008, 57:1-9.
11. Halperin J.J., Golightly M. Lyme borreliosis in Bell's palsy. Long Island Neuroborreliosis Collaborative Study Group. Neurology 1992, 42:1268-1270.
12. Tuerlinckx D., Bodart E., Garrino M.G., et al. Clinical data and cerebrospinal fluid findings in Lyme meningitis versus aseptic meningitis. Eur J Pediatr 2003, 162:150-153.
13. Shah S.S., Zaoutis T.E., Turnquist J., et al. Early differentiation of Lyme from enteroviral meningitis. Pediatr Infect Dis J 2005, 24:542-545.
14. Garro A.C., Rutman M., Simonsen K., et al. Prospective validation of a clinical prediction model for Lyme meningitis in children. Pediatrics 2009, 123:e829-e834.
15. Kan L., Sood S.K., Maytal J. Pseudotumor cerebri in Lyme disease: a case report and literature review. Pediatr Neurol 1998, 18:439-441.
16. Sibony P., Halperin J., Coyle P., et al. Reactive Lyme serology in patients with optic neuritis and papilledema. JNeuroophthalmol 2005, 25:71-82.
17. Blanc F., Ballonzoli L., Marcel C., et al. Lyme optic neuritis. JNeurol Sci 2010, 295:117-119.
18. Halperin J.J. Facial nerve palsy associated with Lyme disease. Muscle Nerve 2003, 28:516-517.
19. Halperin J.J., Luft B.J., Volkman D.J., et al. Lyme neuroborreliosis - peripheral nervous system manifestations. Brain 1990, 113:1207-1221.
20. Muley S.A., Parry G.J. Antibiotic responsive demyelinating neuropathy related to Lyme disease. Neurology 2009, 72:1786-1787.
21. Logigian E.L., Kaplan R.F., Steere A.C. Chronic neurologic manifestations of Lyme disease. NEngl J Med 1990, 323:1438-1444.
22. Halperin J.J., Little B.W., Coyle P.K., et al. Lyme disease - a treatable cause of peripheral neuropathy. Neurology 1987, 37:1700-1706.
23. Ackermann R., Rehse K.B., Gollmer E., et al. Chronic neurologic manifestations of erythema migrans borreliosis. Ann N Y Acad Sci 1988, 539:16-23.
24. Kalina P., Decker A., Kornel E., et al. Lyme disease of the brainstem. Neuroradiology 2005, 47:903-907.
25. Halperin J.J., Luft B.J., Anand A.K., et al. Lyme neuroborreliosis: central nervous system manifestations. Neurology 1989, 39:753-759.
26. Kaplan R.F., Jones-Woodward L. Lyme encephalopathy: a neuropsychological perspective. Semin Neurol 1997, 17:31-37.
27. Halperin J.J., Krupp L.B., Golightly M.G., et al. Lyme borreliosis-associated encephalopathy. Neurology 1990, 40:1340-1343.
28. Hinckley A.F., Connally N.P., Meek J.I., et al. Lyme disease testing by large commercial laboratories in the United States. Clin Infect Dis 2014, 59:676-681.
29. Luo N., Johnson J., Shaw J., et al. Self-reported health status of the general adult U.S. population as assessed by the EQ-5D and Health Utilities Index. Med Care 2005, 43:1078-1086.
30. Hammers Berggren S., Hansen K., Lebech A.M., et al. Borrelia burgdorferi-specific intrathecal antibody production in neuroborreliosis: a follow-up study. Neurology 1993, 43:169-175.
31. Halperin J.J., Shapiro E.D., Logigian E.L., et al. Practice parameter: treatment of nervous system Lyme disease. Neurology 2007, 69:91-102.
32. Ljostad U., Skogvoll E., Eikeland R., et al. Oral doxycycline versus intravenous ceftriaxone for European Lyme neuroborreliosis: a multicentre, non-inferiority, double-blind, randomised trial. Lancet Neurol 2008, 7:690-695.
33. Bremell D., Dotevall L. Oral doxycycline for Lyme neuroborreliosis with symptoms of encephalitis, myelitis, vasculitis or intracranial hypertension. Eur J Neurol 2014, 21:1162-1167.